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Experiment set3IT040 for
Methanococcus maripaludis JJ
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formate McAA pyroxidine HCl dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-5.8
-17.3
hypothetical protein
compare
MMJJ
_RS06625
-5.3
-3.1
pyruvate synthase subunit PorB
compare
MMJJ
_RS02045
-5.3
-4.7
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS04200
-5.2
-7.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06860
-5.1
-5.2
hypothetical protein
compare
MMJJ
_RS03270
-4.9
-3.8
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS05450
-4.9
-18.1
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS05650
-4.8
-3.3
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS03055
-4.8
-4.0
hypothetical protein
compare
MMJJ
_RS04970
-4.7
-2.7
DUF655 domain-containing protein
compare
MMJJ
_RS06240
-4.7
-4.4
dihydropteroate synthase-like protein
compare
MMJJ
_RS00275
-4.7
-3.8
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03110
-4.5
-5.3
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS04485
-4.5
-10.0
riboflavin synthase
compare
MMJJ
_RS01600
-4.4
-4.2
radical SAM protein
compare
MMJJ
_RS06695
-4.4
-4.4
amidohydrolase
compare
MMJJ
_RS08250
-4.3
-8.6
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS01935
-4.3
-5.8
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS06040
-4.2
-5.6
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS03190
-4.2
-2.9
phosphopyruvate hydratase
compare
MMJJ
_RS00270
-4.1
-5.2
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS05590
-4.1
-3.2
homoserine dehydrogenase
compare
MMJJ
_RS03895
-4.1
-4.2
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS03095
-4.0
-3.5
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS06390
-4.0
-2.8
NADPH-dependent F420 reductase
compare
MMJJ
_RS02090
-4.0
-7.9
tyramine--L-glutamate ligase
compare
MMJJ
_RS01755
-3.9
-2.7
ferrous iron transport protein B
compare
MMJJ
_RS05575
-3.9
-6.8
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS07670
-3.9
-18.3
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS06490
-3.8
-4.5
methanogenesis marker 2 protein
compare
MMJJ
_RS04995
-3.8
-8.0
Tfx family DNA-binding protein
compare
MMJJ
_RS07665
-3.8
-22.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS05535
-3.8
-15.0
hypothetical protein
compare
MMJJ
_RS06750
-3.8
-3.2
homoaconitase large subunit
compare
MMJJ
_RS05950
-3.8
-4.5
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS06155
-3.8
-7.5
phosphatidylglycerophosphatase A
compare
MMJJ
_RS03670
-3.7
-6.7
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS05445
-3.7
-3.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS07655
-3.7
-15.8
hypothetical protein
compare
MMJJ
_RS07000
-3.7
-2.8
TrkH family potassium uptake protein
compare
MMJJ
_RS07720
-3.7
-3.4
UPF0058 family protein
compare
MMJJ
_RS08020
-3.7
-9.4
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS08625
-3.6
-8.6
magnesium/cobalt transporter CorA
compare
MMJJ
_RS04475
-3.6
-6.2
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS06875
-3.6
-4.1
hypothetical protein
compare
MMJJ
_RS04685
-3.5
-11.8
carbamoyltransferase HypF
compare
MMJJ
_RS00370
-3.5
-2.8
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS05260
-3.5
-9.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS09175
-3.5
-2.0
anthranilate synthase component I
compare
MMJJ
_RS06840
-3.5
-5.3
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS06375
-3.5
-6.5
UbiX family flavin prenyltransferase
compare
MMJJ
_RS03840
-3.5
-5.7
DHH family phosphoesterase
compare
MMJJ
_RS08080
-3.5
-12.8
TIGR00300 family protein
compare
MMJJ
_RS05225
-3.4
-1.9
Gar1/Naf1 family protein
compare
MMJJ
_RS00210
-3.4
-3.5
DUF530 family protein
compare
MMJJ
_RS04730
-3.4
-4.0
tyrosine decarboxylase MfnA
compare
MMJJ
_RS05620
-3.4
-6.4
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS03760
-3.4
-4.9
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS01870
-3.4
-2.9
methanogenesis marker 15 protein
compare
MMJJ
_RS03875
-3.4
-5.1
CBS domain-containing protein
compare
MMJJ
_RS03200
-3.4
-3.2
uroporphyrinogen-III synthase
compare
MMJJ
_RS06255
-3.4
-8.3
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS05490
-3.3
-3.9
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS03615
-3.3
-3.1
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS00560
-3.3
-4.4
homoisocitrate dehydrogenase
compare
MMJJ
_RS03125
-3.3
-6.5
GMC oxidoreductase
compare
MMJJ
_RS07360
-3.3
-2.2
TIGR00269 family protein
compare
MMJJ
_RS04050
-3.3
-2.8
dihydroneopterin aldolase family protein
compare
MMJJ
_RS03660
-3.3
-5.3
DUF447 family protein
compare
MMJJ
_RS05935
-3.2
-3.4
Era-like GTP-binding protein
compare
MMJJ
_RS08320
-3.2
-4.2
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS00355
-3.2
-5.0
ribonuclease P protein component 4
compare
MMJJ
_RS04675
-3.2
-9.6
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS08330
-3.2
-4.8
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS01345
-3.2
-5.4
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS07190
-3.2
-6.0
RtcB family protein
compare
MMJJ
_RS06180
-3.1
-4.2
tryptophan--tRNA ligase
compare
MMJJ
_RS03820
-3.1
-5.9
hydrogenase formation protein HypD
compare
MMJJ
_RS01360
-3.1
-3.5
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS06725
-3.1
-12.6
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS03580
-3.1
-3.8
TIGR00303 family protein
compare
MMJJ
_RS04155
-3.1
-8.1
hypothetical protein
compare
MMJJ
_RS05720
-3.1
-4.0
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS06785
-3.1
-8.0
RNA ligase partner protein
compare
MMJJ
_RS07380
-3.1
-11.2
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS02920
-3.1
-2.9
30S ribosomal protein S27ae
compare
MMJJ
_RS00520
-3.0
-8.0
PDGLE domain-containing protein
compare
MMJJ
_RS06910
-3.0
-4.7
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS08000
-3.0
-8.7
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS07950
-3.0
-3.7
4Fe-4S binding protein
compare
MMJJ
_RS04800
-3.0
-7.5
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS03620
-3.0
-5.8
DUF2097 domain-containing protein
compare
MMJJ
_RS04975
-3.0
-2.8
glycosyltransferase family 4 protein
compare
MMJJ
_RS06485
-3.0
-4.1
phosphoglycerate kinase
compare
MMJJ
_RS05610
-2.9
-6.4
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS04565
-2.9
-4.4
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS01475
-2.9
-3.2
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS03150
-2.9
-7.8
2-phospho-L-lactate transferase
compare
MMJJ
_RS06510
-2.8
-4.3
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS03065
-2.8
-11.4
CBS domain-containing protein
compare
MMJJ
_RS05930
-2.8
-2.9
cell division protein SepF
compare
MMJJ
_RS05190
-2.8
-9.0
gamma carbonic anhydrase family protein
compare
MMJJ
_RS03830
-2.8
-12.1
CBS domain-containing protein
compare
MMJJ
_RS07275
-2.7
-4.0
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS07660
-2.7
-11.1
carbonic anhydrase
compare
MMJJ
_RS06915
-2.7
-12.6
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08005
-2.7
-16.0
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07995
-2.7
-7.6
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS04790
-2.7
-4.7
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS06185
-2.7
-6.5
cobalamin biosynthesis protein
compare
MMJJ
_RS00580
-2.7
-2.2
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS03865
-2.7
-2.5
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS05810
-2.6
-6.5
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS07410
-2.6
-5.7
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS08855
-2.6
-6.1
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS05995
-2.6
-2.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS00450
-2.6
-2.3
DUF126 domain-containing protein
compare
MMJJ
_RS00195
-2.6
-5.4
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS08055
-2.6
-5.8
methanogenesis marker 14 protein
compare
MMJJ
_RS08660
-2.6
-3.9
acetylornithine transaminase
compare
MMJJ
_RS04875
-2.6
-2.2
tRNA-Lys
compare
MMJJ
_RS08095
-2.6
-5.6
cobyric acid synthase CobQ
compare
MMJJ
_RS08840
-2.6
-6.2
calcium/sodium antiporter
compare
MMJJ
_RS00045
-2.6
-16.4
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS03295
-2.6
-16.1
PHP domain-containing protein
compare
MMJJ
_RS07945
-2.5
-4.4
4Fe-4S binding protein
compare
MMJJ
_RS03800
-2.5
-11.8
aldolase
compare
MMJJ
_RS01865
-2.5
-7.2
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS06930
-2.5
-3.4
type II methionyl aminopeptidase
compare
MMJJ
_RS01200
-2.5
-3.2
PRC-barrel domain-containing protein
compare
MMJJ
_RS03005
-2.5
-4.4
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS06835
-2.5
-13.5
4Fe-4S binding protein
compare
MMJJ
_RS02275
-2.5
-5.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS05330
-2.5
-2.7
DNA polymerase II large subunit
compare
MMJJ
_RS03785
-2.5
-3.0
hypothetical protein
compare
MMJJ
_RS00050
-2.4
-10.6
AAA family ATPase
compare
MMJJ
_RS07345
-2.4
-6.3
homocysteine biosynthesis protein
compare
MMJJ
_RS00530
-2.4
-12.3
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS01565
-2.4
-8.7
TIGR00267 family protein
compare
MMJJ
_RS00475
-2.4
-1.8
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS01750
-2.4
-2.4
ferrous iron transport protein A
compare
MMJJ
_RS05770
-2.4
-2.3
flagellar protein D
compare
MMJJ
_RS00425
-2.4
-4.8
hypothetical protein
compare
MMJJ
_RS01880
-2.4
-3.3
RlmE family RNA methyltransferase
compare
MMJJ
_RS05360
-2.4
-7.0
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS09375
-2.3
-2.2
hypothetical protein
compare
MMJJ
_RS00040
-2.3
-11.8
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS05655
-2.3
-6.6
HisA/HisF family protein
compare
MMJJ
_RS06805
-2.3
-3.1
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS01690
-2.3
-3.2
methanogenesis marker 12 protein
compare
MMJJ
_RS05375
-2.3
-15.1
radical SAM protein
compare
MMJJ
_RS00570
-2.3
-2.0
ribonuclease P
compare
MMJJ
_RS00215
-2.3
-2.6
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS00055
-2.3
-9.1
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS06215
-2.2
-5.1
agmatinase
compare
MMJJ
_RS02055
-2.2
-12.0
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS07635
-2.2
-15.0
response regulator transcription factor
compare
MMJJ
_RS06855
-2.2
-1.2
DUF2104 domain-containing protein
compare
MMJJ
_RS00205
-2.2
-5.5
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS06110
-2.2
-2.6
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS07640
-2.2
-16.8
cache domain-containing protein
compare
MMJJ
_RS00515
-2.2
-10.7
cobalt transporter CbiM
compare
MMJJ
_RS07370
-2.2
-3.8
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS00065
-2.2
-10.0
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS00070
-2.2
-4.5
CooT family nickel-binding protein
compare
MMJJ
_RS00600
-2.2
-2.7
hydroxymethylbilane synthase
compare
MMJJ
_RS03630
-2.2
-10.5
AMP phosphorylase
compare
MMJJ
_RS04010
-2.2
-8.4
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS00060
-2.2
-15.3
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS08620
-2.1
-3.5
DUF373 family protein
compare
MMJJ
_RS05295
-2.1
-9.3
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS00035
-2.1
-14.3
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS00075
-2.1
-11.4
AAA family ATPase
compare
MMJJ
_RS08535
-2.1
-3.3
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS04985
-2.1
-4.5
glutamyl-tRNA reductase
compare
MMJJ
_RS00360
-2.1
-3.3
adenosylhomocysteinase
compare
MMJJ
_RS00080
-2.1
-12.3
DUF166 domain-containing protein
compare
MMJJ
_RS03160
-2.1
-12.1
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS07155
-2.1
-8.1
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS06730
-2.1
-6.1
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS04595
-2.0
-6.0
hypothetical protein
compare
MMJJ
_RS07350
-2.0
-3.4
4Fe-4S binding protein
compare
MMJJ
_RS09135
-2.0
-8.8
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS07785
-2.0
-2.8
fumarate reductase subunit A
compare
MMJJ
_RS09190
-2.0
-2.3
tryptophan synthase subunit beta
compare
MMJJ
_RS01810
-2.0
-2.5
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS07415
-2.0
-3.4
polyprenyl diphosphate synthase
compare
MMJJ
_RS04110
-2.0
-5.2
hypothetical protein
compare
MMJJ
_RS04615
-2.0
-5.2
methanogenesis marker 3 protein
compare
MMJJ
_RS08340
-2.0
-4.2
archaeoflavoprotein AfpA
compare
MMJJ
_RS04520
-1.9
-5.0
coenzyme F430 synthase
compare
MMJJ
_RS03060
-1.9
-2.3
methanogenesis marker 7 protein
compare
MMJJ
_RS07705
-1.9
-3.7
GTP-binding protein EngB
compare
MMJJ
_RS05380
-1.9
-1.8
hypothetical protein
compare
MMJJ
_RS03115
-1.9
-6.2
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS02935
-1.9
-2.6
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS06700
-1.9
-3.6
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS08325
-1.9
-2.4
glycosyltransferase family 2 protein
compare
MMJJ
_RS04670
-1.9
-4.2
DUF2117 domain-containing protein
compare
MMJJ
_RS01785
-1.9
-1.7
50S ribosomal protein L14e
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments