Experiment set3IT040 for Caulobacter crescentus NA1000

Compare to:

PYE with Polymyxin B sulfate 0.005 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
CCNA_01968 +5.0 9.8 pentapeptide repeats containing protein compare
CCNA_01220 +5.0 14.4 7-keto-8-aminopelargonate synthetase compare
CCNA_01730 +4.9 22.1 amidophosphoribosyltransferase compare
CCNA_03281 +4.8 37.6 AsnC-family transcriptional regulator compare
CCNA_02026 +4.8 26.7 hypothetical protein compare
CCNA_03280 +4.6 36.3 pyruvate ferredoxin/flavodoxin oxidoreductase family protein compare
CCNA_02030 +4.6 23.0 hypothetical protein compare
CCNA_03030 +4.6 28.4 cytochrome c2 compare
CCNA_03498 +4.5 36.5 MarR-family transcriptional regulator compare
CCNA_01964 +4.5 24.3 NADH dehydrogenase compare
CCNA_01712 +4.4 40.0 CopY/TcrY family transcriptional repressor compare
CCNA_02416 +4.4 20.6 DNA-binding protein HU compare
CCNA_02315 +4.3 20.9 Cro/CI-family transcriptional regulator compare
CCNA_03043 +4.3 13.5 type IV pilin protein pilA compare
CCNA_01722 +4.3 5.9 hypothetical protein compare
CCNA_03519 +4.3 13.8 PadR-family transcriptional regulator compare
CCNA_02028 +4.2 7.1 NTF2 superfamily protein compare
CCNA_02103 +4.2 21.7 hypothetical protein compare
CCNA_03064 +4.1 29.5 PadR-family transcriptional regulator compare
CCNA_00518 +4.1 17.0 LSU ribosomal protein L25P compare
CCNA_00699 +4.1 23.9 LSU ribosomal protein L28P compare
CCNA_03252 +4.1 24.6 CopY/TcrY-family transcriptional regulator compare
CCNA_01815 +4.0 27.3 nitrogen assimilation regulatory protein NtrC compare
CCNA_03287 +4.0 17.1 PadR-family transcriptional regulator compare
CCNA_02980 +3.9 24.4 tryptophan 2,3-dioxygenase compare
CCNA_01814 +3.9 24.7 nitrogen regulation protein ntrB compare
CCNA_02289 +3.9 31.6 MarR/EmrR family transcriptional regulator compare
CCNA_03271 +3.9 26.2 methionine gamma-lyase compare
CCNA_01780 +3.9 22.3 exopolyphosphatase compare
CCNA_02157 +3.9 20.0 HipB-family transcriptional regulator compare
CCNA_02328 +3.9 2.7 cell cycle regulatory protein GcrA compare
CCNA_02156 +3.8 22.4 hypothetical protein compare
CCNA_01790 +3.8 15.9 protein translocase subunit secG compare
CCNA_03681 +3.8 17.9 ABC transporter ATP-binding protein compare
CCNA_00924 +3.8 26.3 MarR/EmrR family transcriptional regulator compare
CCNA_02025 +3.8 10.7 hypothetical protein compare
CCNA_03289 +3.8 32.7 HicB-family RNA-binding protein compare
CCNA_02957 +3.7 10.8 ArsR-family transcriptional regulator compare
CCNA_03612 +3.7 15.6 HTH XRE-family transcriptional regulator compare
CCNA_03961 +3.7 17.1 hypothetical protein compare
CCNA_02646 +3.7 6.4 cell division protein MraZ compare
CCNA_00521 +3.7 11.5 antitoxin protein compare
CCNA_01223 +3.7 19.8 acyl-CoA synthetase compare
CCNA_02448 +3.7 13.5 hypothetical protein compare
CCNA_01979 +3.7 20.4 LexA repressor compare
CCNA_03680 +3.7 29.2 aminopeptidase N compare
CCNA_02316 +3.7 13.4 hypothetical protein compare
CCNA_00846 +3.6 29.3 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase compare
CCNA_01851 +3.6 24.7 quinol cytochrome oxidase polypeptide II compare
CCNA_00769 +3.6 16.0 TetR family transcriptional regulator compare
CCNA_00162 +3.6 14.0 hypothetical protein compare
CCNA_02663 +3.6 7.0 DnaK suppressor protein DksA compare
CCNA_01775 +3.6 16.4 phosphoribosylformylglycinamidine cyclo-ligase compare
CCNA_02447 +3.5 15.2 PspA/IM30 family regulatory protein compare
CCNA_03325 +3.5 14.3 hypothetical protein compare
CCNA_00684 +3.5 16.1 anti-sigma factor, ChrR-family compare
CCNA_01094 +3.5 7.7 hypothetical protein compare
CCNA_00161 +3.5 27.7 hypothetical protein compare
CCNA_01242 +3.5 19.5 amino acid permease compare
CCNA_00756 +3.5 5.0 hypothetical protein compare
CCNA_01573 +3.5 15.3 ArsR-family transcriptional regulator compare
CCNA_03989 +3.5 26.1 MarR-family HTH transcriptional regulator / N-acyltransferase compare
CCNA_01221 +3.4 4.8 acyl carrier protein compare
CCNA_01217 +3.4 22.8 phosphatidylglycerophosphate synthase compare
CCNA_03479 +3.4 19.3 MarR-family transcriptional regulator compare
CCNA_00292 +3.4 8.2 phosphate transport system permease protein pstC compare
CCNA_01453 +3.4 10.5 electron transport complex I subunit, NADH-ubiquinone oxidoreductase compare
CCNA_03949 +3.4 13.4 hypothetical protein compare
CCNA_01931 +3.4 20.0 TetR-family transcriptional regulator compare
CCNA_01684 +3.4 17.8 phenylalanine-4-hydroxylase compare
CCNA_00939 +3.4 13.6 MarR-family transcriptional regulator compare
CCNA_01008 +3.3 23.9 urocanate hydratase compare
CCNA_01445 +3.3 14.4 hypothetical protein compare
CCNA_01624 +3.3 6.4 orotate phosphoribosyltransferase compare
CCNA_02000 +3.3 6.2 SSU ribosomal protein S2P compare
CCNA_01186 +3.3 13.2 hypothetical protein compare
CCNA_01840 +3.3 24.8 MerR-family transcriptional regulator compare
CCNA_03938 +3.3 10.2 hypothetical protein compare
CCNA_02910 +3.3 26.6 TonB-dependent receptor compare
CCNA_03893 +3.3 8.6 hypothetical protein compare
CCNA_01739 +3.3 16.2 LSU ribosomal protein L9P compare
CCNA_02225 +3.3 15.2 ArsR family/SAM-dependent transcriptional regulator compare
CCNA_02021 +3.3 11.5 hypothetical protein compare
CCNA_02133 +3.3 13.5 glucokinase compare
CCNA_02866 +3.2 9.5 hypothetical protein compare
CCNA_01059 +3.2 10.7 S-layer protein rsaA compare
CCNA_03951 +3.2 12.1 hypothetical protein compare
CCNA_01526 +3.2 13.0 flagellar biosynthesis regulatory protein flaF compare
CCNA_02591 +3.2 18.1 glutaredoxin compare
CCNA_01058 +3.2 16.7 helix-turn-helix transcriptional regulator compare
CCNA_00962 +3.2 17.4 MarR-family transcriptional regulator compare
CCNA_00920 +3.2 10.3 hypothetical protein compare
CCNA_03689 +3.2 22.4 alanine dehydrogenase compare
CCNA_02576 +3.2 21.9 phosphoribosylamidoimidazole-succinocarboxamide synthase compare
CCNA_03379 +3.2 7.1 Cro/CI family transcriptional regulator compare
CCNA_03464 +3.2 14.3 glycine cleavage system H protein compare
CCNA_00210 +3.1 23.7 TonB-dependent receptor compare
CCNA_03123 +3.1 17.5 ArsR-family transcriptional regulator compare
CCNA_01218 +3.1 9.5 sphingosine kinase/diacylglycerol kinase-related protein compare
CCNA_01583 +3.1 7.4 phosphate-binding protein compare
CCNA_02617 +3.1 23.3 histidinol-phosphate aminotransferase compare
CCNA_01942 +3.1 13.9 Rrf2 family protein compare
CCNA_02836 +3.1 21.1 hypothetical protein compare
CCNA_00505 +3.1 13.9 ubiquinol-cytochrome c reductase iron-sulfur subunit compare
CCNA_02616 +3.1 20.2 4-hydroxyphenylpyruvate dioxygenase compare
CCNA_01848 +3.1 19.3 quinol cytochrome oxidase polypeptide IV compare
CCNA_00954 +3.1 20.3 AAA-family response regulator flbD compare
CCNA_01420 +3.0 13.5 NrdR family transcriptional regulator compare
CCNA_03391 +3.0 15.3 Cro/CI family transcriptional regulator compare
CCNA_00781 +3.0 18.4 two-component receiver protein CpdR compare
CCNA_01593 +3.0 15.1 Xaa-pro aminopeptidase compare
CCNA_03062 +3.0 16.6 cell wall hydrolase family protein compare
CCNA_01763 +3.0 16.4 multifunctional aminopeptidase compare
CCNA_00031 +3.0 14.5 toxin protein VapC compare
CCNA_01212 +3.0 17.3 dATP pyrophosphohydrolase compare
CCNA_01913 +3.0 19.0 MarR-family transcriptional regulator compare
CCNA_03072 +3.0 11.5 TetR-family transcriptional regulator compare
CCNA_01802 +2.9 7.0 hypothetical protein compare
CCNA_02878 +2.9 3.6 hypothetical protein compare
CCNA_03420 +2.9 12.1 hypothetical protein compare
CCNA_01063 +2.9 13.6 UDP-perosamine 4-acetyl transferase compare
CCNA_03089 +2.9 15.4 hypothetical protein compare
CCNA_01801 +2.9 11.2 hypothetical protein compare
CCNA_00149 +2.9 5.5 Cro/CI-family transcriptional regulator compare
CCNA_01849 +2.9 17.0 quinol cytochrome oxidase polypeptide III compare
CCNA_03215 +2.9 17.3 ARO8 family aminotransferase/HTH DNA-binding protein compare
CCNA_02553 +2.9 18.1 ATP-dependent clp protease ATP-binding subunit ClpA compare
CCNA_01804 +2.9 17.3 glutathione peroxidase compare
CCNA_02419 +2.8 10.7 TonB1 protein compare
CCNA_00032 +2.8 9.9 antitoxin protein VapB compare
CCNA_02073 +2.8 8.6 cupin domain transcriptional regulator compare
CCNA_00944 +2.8 14.8 flagellar hook length determination protein compare
CCNA_01222 +2.8 10.1 NADH-ubiquinone oxidoreductase compare
CCNA_01361 +2.8 7.5 PepSY superfamily protein compare
CCNA_00441 +2.8 13.5 chemotaxis receiver domain protein cheYI compare
CCNA_02339 +2.8 15.8 methyltransferase compare
CCNA_01279 +2.8 12.3 inorganic polyphosphate/ATP-NAD kinase compare
CCNA_01850 +2.8 19.2 quinol cytochrome oxidase polypeptide I compare
CCNA_00375 +2.8 9.1 hypothetical protein compare
CCNA_00945 +2.7 14.2 chemotaxis protein MotD compare
CCNA_00447 +2.7 11.9 chemotaxis protein cheD compare
CCNA_02063 +2.7 8.8 beta-barrel assembly machine (BAM) protein BamD compare
CCNA_03129 +2.7 15.2 peptidoglycan-specific endopeptidase, M23 family compare
CCNA_02341 +2.7 12.3 small heat shock protein compare
CCNA_00299 +2.7 15.7 phosphoribosylamine--glycine ligase compare
CCNA_00947 +2.7 19.2 flagellar hook protein FlgE compare
CCNA_00803 +2.7 10.0 chemotaxis protein cheW compare
CCNA_R0037 +2.7 7.0 tRNA-Glu compare
CCNA_01525 +2.7 15.5 flagellar biosynthesis repressor flbT compare
CCNA_01655 +2.7 12.7 cyclophilin-type peptidylprolyl cis-trans isomerase compare
CCNA_03688 +2.7 14.9 AsnC-family transcriptional regulator compare
CCNA_03936 +2.7 9.0 hypothetical protein compare
CCNA_00834 +2.7 10.4 flagellin FljM compare
CCNA_02728 +2.7 12.6 hypothetical protein compare
CCNA_02287 +2.7 12.3 TetR-family transcriptional regulator compare
CCNA_01742 +2.7 12.8 hypothetical protein compare
CCNA_02467 +2.6 14.1 polyisoprenylphosphate hexose-1-phosphotransferase pssZ compare
CCNA_00215 +2.6 13.5 SapC surface layer protein compare
CCNA_02567 +2.6 17.3 sensory transduction histidine kinase pleC compare
CCNA_01678 +2.6 12.9 arginine N-succinyltransferase, beta chain compare
CCNA_00163 +2.6 16.3 exopolysaccharide transport family protein compare
CCNA_03400 +2.6 7.4 hypothetical protein compare
CCNA_02367 +2.6 15.9 CelR-family transcriptional regulator compare
CCNA_03622 +2.6 15.0 beta-lactamase repressor compare
CCNA_02575 +2.6 6.8 hypothetical protein compare
CCNA_02180 +2.6 5.5 iron-sulfur cluster assembly/repair protein ApbC compare
CCNA_02132 +2.6 9.2 LacI-family transcriptional regulator compare
CCNA_03372 +2.6 8.2 bacterioferritin-associated ferredoxin compare
CCNA_02242 +2.6 12.4 PHB granule-associated protein, phasin2 compare
CCNA_03805 +2.6 16.9 PadR-family transcriptional regulator compare
CCNA_02619 +2.6 16.0 stomatin/prohibitin-related protein compare
CCNA_01679 +2.6 13.2 succinylglutamic semialdehyde dehydrogenase compare
CCNA_02835 +2.6 9.1 CpxP-related protein compare
CCNA_01528 +2.6 12.5 flagellin fljK compare
CCNA_02846 +2.5 16.7 DegP/HtrA-family serine protease compare
CCNA_02586 +2.5 14.9 phosphoribosylformylglycinamidine synthase II compare
CCNA_00148 +2.5 9.1 hypothetical protein compare
CCNA_00368 +2.5 14.6 phosphonates transport system permease protein phnE compare
CCNA_02644 +2.5 6.7 cell division protein FtsL compare
CCNA_03808 +2.5 16.9 organic solvent resistance transport system Ttg2C protein compare
CCNA_00352 +2.5 12.6 integral membrane protein compare
CCNA_01393 +2.5 15.3 soluble lytic murein transglycosylase compare
CCNA_01226 +2.5 7.2 hypothetical protein compare
CCNA_00998 +2.5 11.9 ROS/MUCR transcriptional regulator compare
CCNA_00950 +2.5 17.1 flagellar M-ring protein FliF compare
CCNA_01009 +2.5 14.2 N-formylglutamate deformylase compare
CCNA_01235 +2.5 11.6 AcrR-family transcriptional regulator compare
CCNA_01020 +2.5 12.6 LacI-family transcriptional regulator compare
CCNA_00027 +2.5 4.4 2OG-Fe(II) oxygenase compare
CCNA_01813 +2.5 11.0 tRNA-dihydrouridine synthase compare
CCNA_02042 +2.5 15.7 trigger factor chaperone compare
CCNA_00440 +2.5 7.2 STAS domain protein compare
CCNA_03012 +2.5 17.0 peroxiredoxin compare
CCNA_01057 +2.5 15.1 hypothetical protein compare
CCNA_00028 +2.5 9.2 TonB-dependent receptor compare
CCNA_00919 +2.5 11.4 hypothetical protein compare
CCNA_01959 +2.5 4.0 3-dehydroquinate dehydratase compare
CCNA_03619 +2.5 14.6 zinc metalloprotease compare
CCNA_03807 +2.5 11.0 organic solvent resistance transport system Ttg2D protein compare
CCNA_02805 +2.5 11.2 hypothetical protein compare


Specific Phenotypes

For 10 genes in this experiment

For stress Polymyxin B sulfate in Caulobacter crescentus NA1000

For stress Polymyxin B sulfate across organisms