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Experiment set3IT039 for
Methanococcus maripaludis JJ
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formate McAA folic acid dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.3
13.4
hypothetical protein
compare
MMJJ
_RS04005
+0.8
6.6
acetate--CoA ligase family protein
compare
MMJJ
_RS08830
+0.7
2.9
hypothetical protein
compare
MMJJ
_RS05685
+0.6
4.3
class III signal peptide-containing protein
compare
MMJJ
_RS05915
+0.6
2.4
multiprotein bridging factor aMBF1
compare
MMJJ
_RS03250
+0.6
1.9
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS07235
+0.6
5.3
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS07920
+0.6
4.4
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS03725
+0.6
2.6
sulfurtransferase TusA family protein
compare
MMJJ
_RS04375
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS07240
+0.5
4.5
MBL fold metallo-hydrolase
compare
MMJJ
_RS09120
+0.5
0.7
aspartate kinase
compare
MMJJ
_RS02270
+0.5
2.4
HEPN domain-containing protein
compare
MMJJ
_RS08225
+0.5
1.7
peptidylprolyl isomerase
compare
MMJJ
_RS06275
+0.5
2.4
hypothetical protein
compare
MMJJ
_RS06190
+0.5
3.5
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS07185
+0.5
1.6
DUF371 domain-containing protein
compare
MMJJ
_RS05040
+0.5
3.2
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS07230
+0.5
3.2
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS07220
+0.4
3.5
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS06210
+0.4
2.3
hypothetical protein
compare
MMJJ
_RS06810
+0.4
3.5
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS06770
+0.4
3.4
hypothetical protein
compare
MMJJ
_RS07680
+0.4
3.0
glucose-6-phosphate isomerase
compare
MMJJ
_RS07225
+0.4
2.7
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS08515
+0.4
1.8
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS06735
+0.4
2.9
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07025
+0.4
2.0
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS06680
+0.4
2.0
DUF366 family protein
compare
MMJJ
_RS06675
+0.4
3.1
TIGR01212 family radical SAM protein
compare
MMJJ
_RS07210
+0.4
3.1
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS06710
+0.4
3.1
TldD/PmbA family protein
compare
MMJJ
_RS05525
+0.4
2.3
GTP-binding protein
compare
MMJJ
_RS06740
+0.4
2.3
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS06745
+0.4
2.4
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS07915
+0.4
1.7
CBS domain-containing protein
compare
MMJJ
_RS08520
+0.4
1.4
peptidylprolyl isomerase
compare
MMJJ
_RS07820
+0.4
2.9
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS06470
+0.4
2.7
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS05350
+0.4
1.7
DUF192 domain-containing protein
compare
MMJJ
_RS04105
+0.4
3.2
prepilin peptidase
compare
MMJJ
_RS07450
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS07795
+0.4
2.4
cupin domain-containing protein
compare
MMJJ
_RS07015
+0.4
0.7
PFL family protein
compare
MMJJ
_RS07445
+0.4
2.8
RlmF-related methyltransferase
compare
MMJJ
_RS06505
+0.4
1.2
prephenate dehydratase
compare
MMJJ
_RS08100
+0.4
2.1
hypothetical protein
compare
MMJJ
_RS06205
+0.4
2.5
EamA family transporter
compare
MMJJ
_RS09360
+0.4
2.5
hypothetical protein
compare
MMJJ
_RS05520
+0.3
2.8
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS03775
+0.3
1.1
50S ribosomal protein L15e
compare
MMJJ
_RS06540
+0.3
1.0
DUF2120 domain-containing protein
compare
MMJJ
_RS06515
+0.3
2.9
ribonuclease III
compare
MMJJ
_RS04955
+0.3
2.2
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS01855
+0.3
2.8
MBL fold metallo-hydrolase
compare
MMJJ
_RS06090
+0.3
2.1
hypothetical protein
compare
MMJJ
_RS03360
+0.3
0.5
hypothetical protein
compare
MMJJ
_RS08390
+0.3
0.9
carboxymuconolactone decarboxylase family protein
compare
MMJJ
_RS06500
+0.3
2.3
class I SAM-dependent methyltransferase
compare
MMJJ
_RS03835
+0.3
1.4
DUF504 domain-containing protein
compare
MMJJ
_RS06790
+0.3
2.7
nucleotidyltransferase family protein
compare
MMJJ
_RS07610
+0.3
2.0
DUF2119 domain-containing protein
compare
MMJJ
_RS05580
+0.3
2.1
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS06440
+0.3
2.0
DUF4870 domain-containing protein
compare
MMJJ
_RS09230
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS07750
+0.3
0.6
class III signal peptide-containing protein
compare
MMJJ
_RS05960
+0.3
2.2
DUF169 domain-containing protein
compare
MMJJ
_RS03605
+0.3
1.2
TIGR00297 family protein
compare
MMJJ
_RS06460
+0.3
2.0
cytochrome c
compare
MMJJ
_RS05400
+0.3
1.7
CoA-binding protein
compare
MMJJ
_RS04545
+0.3
0.9
PadR family transcriptional regulator
compare
MMJJ
_RS07270
+0.3
2.4
ribonuclease HII
compare
MMJJ
_RS01395
+0.3
1.8
DUF1894 domain-containing protein
compare
MMJJ
_RS07280
+0.3
1.7
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS06960
+0.3
2.6
CAP domain-containing protein
compare
MMJJ
_RS08455
+0.3
1.6
tetratricopeptide repeat protein
compare
MMJJ
_RS06535
+0.3
2.4
UPF0104 family protein
compare
MMJJ
_RS01825
+0.3
1.8
DNA repair and recombination protein RadB
compare
MMJJ
_RS06455
+0.3
2.3
YeeE/YedE family protein
compare
MMJJ
_RS07825
+0.3
1.2
YciI family protein
compare
MMJJ
_RS09255
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS07480
+0.3
2.3
FAD-dependent oxidoreductase
compare
MMJJ
_RS06950
+0.3
2.1
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS04850
+0.3
1.7
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS07200
+0.3
2.2
MFS transporter
compare
MMJJ
_RS08375
+0.3
2.1
ferritin
compare
MMJJ
_RS06765
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS03730
+0.3
1.8
SWIM zinc finger family protein
compare
MMJJ
_RS07800
+0.3
2.2
AMP-binding protein
compare
MMJJ
_RS01010
+0.3
2.5
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS00745
+0.3
1.4
hypothetical protein
compare
MMJJ
_RS07760
+0.3
1.6
GNAT family N-acetyltransferase
compare
MMJJ
_RS06585
+0.3
1.8
alanine racemase
compare
MMJJ
_RS06085
+0.3
1.2
proteasome assembly chaperone family protein
compare
MMJJ
_RS08160
+0.3
1.4
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMJJ
_RS07495
+0.3
1.6
4Fe-4S binding protein
compare
MMJJ
_RS03515
+0.3
1.9
GPR1/FUN34/YaaH family transporter
compare
MMJJ
_RS00785
+0.3
0.5
hypothetical protein
compare
MMJJ
_RS04345
+0.3
1.2
DUF2080 family transposase-associated protein
compare
MMJJ
_RS02115
+0.3
1.9
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS07885
+0.2
1.9
NERD domain-containing protein
compare
MMJJ
_RS05975
+0.2
1.8
sulfurtransferase TusA family protein
compare
MMJJ
_RS01100
+0.2
0.7
helix-turn-helix domain-containing protein
compare
MMJJ
_RS06665
+0.2
0.9
DUF3236 domain-containing protein
compare
MMJJ
_RS06580
+0.2
1.9
alanine dehydrogenase
compare
MMJJ
_RS06385
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS08310
+0.2
1.5
ZIP family metal transporter
compare
MMJJ
_RS05090
+0.2
1.2
MGMT family protein
compare
MMJJ
_RS03450
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS07385
+0.2
1.8
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS08485
+0.2
0.9
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS04215
+0.2
2.0
DMT family transporter
compare
MMJJ
_RS07215
+0.2
1.9
TIGR00341 family protein
compare
MMJJ
_RS06045
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS05510
+0.2
1.8
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS05355
+0.2
1.6
DUF2121 domain-containing protein
compare
MMJJ
_RS05500
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS05700
+0.2
1.6
metallophosphoesterase
compare
MMJJ
_RS06800
+0.2
1.5
prefoldin subunit alpha
compare
MMJJ
_RS04340
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS01790
+0.2
1.6
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS07815
+0.2
1.7
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS01530
+0.2
0.6
YwbE family protein
compare
MMJJ
_RS00145
+0.2
1.7
aquaporin family protein
compare
MMJJ
_RS00615
+0.2
1.0
nucleoside deaminase
compare
MMJJ
_RS02165
+0.2
1.6
ABC transporter substrate-binding protein
compare
MMJJ
_RS07175
+0.2
1.7
DEAD/DEAH box helicase
compare
MMJJ
_RS06685
+0.2
1.8
S-layer protein
compare
MMJJ
_RS00150
+0.2
1.2
DUF2180 family protein
compare
MMJJ
_RS07740
+0.2
1.5
DUF2334 domain-containing protein
compare
MMJJ
_RS00555
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS00500
+0.2
0.9
GNAT family N-acetyltransferase
compare
MMJJ
_RS03715
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05660
+0.2
1.3
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS07035
+0.2
0.3
glycosyl transferase
compare
MMJJ
_RS06135
+0.2
1.7
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS05505
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS03905
+0.2
1.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS08350
+0.2
1.8
heavy metal translocating P-type ATPase
compare
MMJJ
_RS06590
+0.2
1.6
sodium:alanine symporter family protein
compare
MMJJ
_RS07890
+0.2
1.2
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS07835
+0.2
1.4
UPF0489 family protein
compare
MMJJ
_RS02230
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS05900
+0.2
1.5
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS09365
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS06430
+0.2
1.2
haloacid dehalogenase
compare
MMJJ
_RS03945
+0.2
1.3
mechanosensitive ion channel family protein
compare
MMJJ
_RS03285
+0.2
1.0
gamma-glutamylcyclotransferase
compare
MMJJ
_RS07985
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS08305
+0.2
1.0
peroxiredoxin
compare
MMJJ
_RS04390
+0.2
1.5
rhomboid family intramembrane serine protease
compare
MMJJ
_RS01380
+0.2
1.1
DUF1890 domain-containing protein
compare
MMJJ
_RS08285
+0.2
1.3
class I SAM-dependent methyltransferase
compare
MMJJ
_RS07010
+0.2
0.9
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS07255
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS04510
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS07260
+0.2
1.2
PspC domain-containing protein
compare
MMJJ
_RS00155
+0.2
1.5
DUF2193 domain-containing protein
compare
MMJJ
_RS09005
+0.2
1.5
N-6 DNA methylase
compare
MMJJ
_RS06105
+0.2
1.3
DUF99 family protein
compare
MMJJ
_RS06280
+0.2
1.4
hypothetical protein
compare
MMJJ
_RS08705
+0.2
1.2
AEC family transporter
compare
MMJJ
_RS06550
+0.2
1.3
ABC transporter permease
compare
MMJJ
_RS00715
+0.2
1.2
DUF1847 domain-containing protein
compare
MMJJ
_RS04120
+0.2
1.3
amino acid ABC transporter ATP-binding protein
compare
MMJJ
_RS07865
+0.2
1.0
zinc ribbon domain-containing protein
compare
MMJJ
_RS03290
+0.2
1.4
amidohydrolase
compare
MMJJ
_RS07855
+0.2
1.2
YkgJ family cysteine cluster protein
compare
MMJJ
_RS03220
+0.2
1.4
inosine/xanthosine triphosphatase
compare
MMJJ
_RS00090
+0.2
1.2
4Fe-4S binding protein
compare
MMJJ
_RS04245
+0.2
1.0
flavoprotein
compare
MMJJ
_RS05750
+0.2
1.4
flagellar accessory protein FlaH
compare
MMJJ
_RS02265
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS08045
+0.2
1.4
transporter substrate-binding domain-containing protein
compare
MMJJ
_RS04580
+0.2
1.3
2-phosphosulfolactate phosphatase
compare
MMJJ
_RS01835
+0.2
1.3
tRNA pseudouridine(13) synthase TruD
compare
MMJJ
_RS07440
+0.2
1.3
metallophosphoesterase
compare
MMJJ
_RS07910
+0.2
1.2
CBS domain-containing protein
compare
MMJJ
_RS09065
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS00790
+0.2
1.0
ribonuclease H family protein
compare
MMJJ
_RS03040
+0.2
1.0
lactate utilization protein
compare
MMJJ
_RS02340
+0.2
1.1
SAM-dependent methyltransferase
compare
MMJJ
_RS05890
+0.2
1.2
molybdate ABC transporter substrate-binding protein
compare
MMJJ
_RS06080
+0.2
1.1
serine/threonine protein kinase
compare
MMJJ
_RS01955
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS06285
+0.2
1.0
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS04815
+0.2
0.6
TIM barrel protein
compare
MMJJ
_RS07695
+0.2
1.3
glycoside hydrolase family 15 protein
compare
MMJJ
_RS04625
+0.2
1.2
SLC13 family permease
compare
MMJJ
_RS06520
+0.2
1.1
TldD/PmbA family protein
compare
MMJJ
_RS06115
+0.2
1.1
pyruvate kinase
compare
MMJJ
_RS04825
+0.1
1.3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS04585
+0.1
1.0
phenylacetate--CoA ligase
compare
MMJJ
_RS06640
+0.1
1.0
YfcE family phosphodiesterase
compare
MMJJ
_RS06120
+0.1
1.1
DUF4013 domain-containing protein
compare
MMJJ
_RS04135
+0.1
0.6
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS02280
+0.1
1.1
sulfate permease
compare
MMJJ
_RS02965
+0.1
0.9
RimK-like ATPgrasp N-terminal domain-containing protein
compare
MMJJ
_RS09145
+0.1
0.9
exodeoxyribonuclease III
compare
MMJJ
_RS08370
+0.1
0.6
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments