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Experiment set3IT038 for
Methanococcus maripaludis JJ
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formate McAA folic acid dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS06860
-6.4
-4.4
hypothetical protein
compare
MMJJ
_RS00235
-6.2
-22.0
hypothetical protein
compare
MMJJ
_RS06695
-5.4
-3.7
amidohydrolase
compare
MMJJ
_RS02090
-5.2
-6.2
tyramine--L-glutamate ligase
compare
MMJJ
_RS07360
-5.1
-2.8
TIGR00269 family protein
compare
MMJJ
_RS05070
-4.8
-3.3
DNA primase catalytic subunit PriS
compare
MMJJ
_RS00570
-4.7
-3.2
ribonuclease P
compare
MMJJ
_RS04200
-4.7
-9.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06225
-4.7
-3.2
adenosylmethionine decarboxylase
compare
MMJJ
_RS06855
-4.6
-2.4
DUF2104 domain-containing protein
compare
MMJJ
_RS01870
-4.6
-3.1
methanogenesis marker 15 protein
compare
MMJJ
_RS06910
-4.5
-4.3
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS06625
-4.5
-3.7
pyruvate synthase subunit PorB
compare
MMJJ
_RS05450
-4.4
-16.8
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS00580
-4.4
-3.1
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS03200
-4.4
-3.0
uroporphyrinogen-III synthase
compare
MMJJ
_RS02045
-4.4
-4.1
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS05445
-4.2
-3.4
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS03270
-4.2
-4.1
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS03840
-4.2
-4.9
DHH family phosphoesterase
compare
MMJJ
_RS09375
-4.1
-2.8
hypothetical protein
compare
MMJJ
_RS03820
-4.1
-5.5
hydrogenase formation protein HypD
compare
MMJJ
_RS03865
-4.0
-2.0
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS08020
-4.0
-10.1
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03580
-4.0
-5.3
TIGR00303 family protein
compare
MMJJ
_RS06875
-4.0
-5.2
hypothetical protein
compare
MMJJ
_RS05650
-3.9
-4.6
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS05225
-3.9
-1.6
Gar1/Naf1 family protein
compare
MMJJ
_RS05535
-3.9
-17.5
hypothetical protein
compare
MMJJ
_RS07665
-3.9
-23.4
formate dehydrogenase subunit alpha
compare
MMJJ
_RS03785
-3.8
-3.7
hypothetical protein
compare
MMJJ
_RS06510
-3.8
-4.6
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS06040
-3.8
-6.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08250
-3.8
-9.5
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS06725
-3.8
-16.1
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS06390
-3.8
-2.6
NADPH-dependent F420 reductase
compare
MMJJ
_RS05575
-3.8
-7.1
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS01750
-3.7
-4.1
ferrous iron transport protein A
compare
MMJJ
_RS06490
-3.7
-4.6
methanogenesis marker 2 protein
compare
MMJJ
_RS04685
-3.7
-12.9
carbamoyltransferase HypF
compare
MMJJ
_RS05260
-3.7
-8.4
ATP-grasp domain-containing protein
compare
MMJJ
_RS00270
-3.6
-4.4
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS05935
-3.6
-3.3
Era-like GTP-binding protein
compare
MMJJ
_RS04155
-3.6
-9.0
hypothetical protein
compare
MMJJ
_RS08625
-3.6
-9.4
magnesium/cobalt transporter CorA
compare
MMJJ
_RS06840
-3.6
-5.4
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS05930
-3.6
-3.1
cell division protein SepF
compare
MMJJ
_RS08330
-3.5
-5.3
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS03110
-3.5
-6.2
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS07670
-3.5
-18.2
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS07655
-3.5
-14.6
hypothetical protein
compare
MMJJ
_RS04995
-3.5
-8.2
Tfx family DNA-binding protein
compare
MMJJ
_RS07380
-3.5
-13.3
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS01935
-3.5
-6.0
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS04485
-3.4
-13.1
riboflavin synthase
compare
MMJJ
_RS07410
-3.4
-6.5
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS05380
-3.4
-2.1
hypothetical protein
compare
MMJJ
_RS03670
-3.4
-6.4
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS06915
-3.3
-15.8
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08005
-3.3
-18.0
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS02935
-3.3
-3.8
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS00355
-3.3
-4.8
ribonuclease P protein component 4
compare
MMJJ
_RS04800
-3.3
-8.5
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS06255
-3.2
-7.4
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS04730
-3.2
-4.2
tyrosine decarboxylase MfnA
compare
MMJJ
_RS00520
-3.2
-7.7
PDGLE domain-containing protein
compare
MMJJ
_RS08080
-3.2
-9.2
TIGR00300 family protein
compare
MMJJ
_RS04790
-3.1
-4.9
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS06485
-3.1
-4.1
phosphoglycerate kinase
compare
MMJJ
_RS06155
-3.1
-5.9
phosphatidylglycerophosphatase A
compare
MMJJ
_RS01880
-3.1
-4.3
RlmE family RNA methyltransferase
compare
MMJJ
_RS00475
-3.1
-3.4
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS03875
-3.1
-6.7
CBS domain-containing protein
compare
MMJJ
_RS03055
-3.1
-4.9
hypothetical protein
compare
MMJJ
_RS03615
-3.1
-4.7
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS08000
-3.1
-10.2
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS04675
-3.0
-7.4
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS08055
-3.0
-7.7
methanogenesis marker 14 protein
compare
MMJJ
_RS00450
-3.0
-2.8
DUF126 domain-containing protein
compare
MMJJ
_RS03125
-3.0
-6.8
GMC oxidoreductase
compare
MMJJ
_RS01565
-3.0
-9.6
TIGR00267 family protein
compare
MMJJ
_RS03295
-3.0
-15.3
PHP domain-containing protein
compare
MMJJ
_RS01600
-3.0
-3.8
radical SAM protein
compare
MMJJ
_RS07430
-3.0
-4.5
ribonuclease VapC
compare
MMJJ
_RS01755
-3.0
-3.7
ferrous iron transport protein B
compare
MMJJ
_RS06375
-2.9
-5.3
UbiX family flavin prenyltransferase
compare
MMJJ
_RS02275
-2.9
-5.7
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03620
-2.9
-5.3
DUF2097 domain-containing protein
compare
MMJJ
_RS07945
-2.9
-5.3
4Fe-4S binding protein
compare
MMJJ
_RS07660
-2.9
-13.6
carbonic anhydrase
compare
MMJJ
_RS07785
-2.9
-3.9
fumarate reductase subunit A
compare
MMJJ
_RS05490
-2.9
-3.2
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS04655
-2.8
-7.9
FAD-dependent oxidoreductase
compare
MMJJ
_RS03115
-2.8
-5.4
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS03095
-2.8
-3.5
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS08095
-2.8
-6.5
cobyric acid synthase CobQ
compare
MMJJ
_RS00600
-2.8
-4.1
hydroxymethylbilane synthase
compare
MMJJ
_RS05065
-2.7
-5.3
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS04985
-2.7
-5.4
glutamyl-tRNA reductase
compare
MMJJ
_RS04520
-2.7
-7.3
coenzyme F430 synthase
compare
MMJJ
_RS02920
-2.7
-3.7
30S ribosomal protein S27ae
compare
MMJJ
_RS02040
-2.7
-1.9
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS01690
-2.7
-4.5
methanogenesis marker 12 protein
compare
MMJJ
_RS07350
-2.7
-4.7
4Fe-4S binding protein
compare
MMJJ
_RS08660
-2.7
-4.7
acetylornithine transaminase
compare
MMJJ
_RS08320
-2.7
-2.6
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS06215
-2.7
-5.3
agmatinase
compare
MMJJ
_RS07705
-2.6
-5.0
GTP-binding protein EngB
compare
MMJJ
_RS03660
-2.6
-5.4
DUF447 family protein
compare
MMJJ
_RS09130
-2.6
-2.3
NFYB/HAP3 family transcription factor subunit
compare
MMJJ
_RS05995
-2.6
-2.7
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06785
-2.6
-6.9
RNA ligase partner protein
compare
MMJJ
_RS00050
-2.6
-13.5
AAA family ATPase
compare
MMJJ
_RS03065
-2.6
-12.4
CBS domain-containing protein
compare
MMJJ
_RS00045
-2.6
-15.8
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS03830
-2.5
-10.3
CBS domain-containing protein
compare
MMJJ
_RS01345
-2.5
-5.2
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS05655
-2.5
-6.9
HisA/HisF family protein
compare
MMJJ
_RS08335
-2.5
-2.7
ABC transporter ATP-binding protein
compare
MMJJ
_RS00205
-2.5
-6.4
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS05810
-2.5
-6.9
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS03895
-2.5
-3.7
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS03190
-2.5
-3.9
phosphopyruvate hydratase
compare
MMJJ
_RS07720
-2.5
-2.9
UPF0058 family protein
compare
MMJJ
_RS01355
-2.5
-4.0
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS08340
-2.5
-4.7
archaeoflavoprotein AfpA
compare
MMJJ
_RS08855
-2.5
-7.1
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS05620
-2.5
-6.3
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS00560
-2.4
-3.5
homoisocitrate dehydrogenase
compare
MMJJ
_RS00065
-2.4
-11.6
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS07345
-2.4
-7.1
homocysteine biosynthesis protein
compare
MMJJ
_RS06250
-2.4
-3.2
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS06705
-2.4
-5.7
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS07155
-2.4
-9.8
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS00215
-2.4
-3.5
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS01200
-2.4
-3.4
PRC-barrel domain-containing protein
compare
MMJJ
_RS08795
-2.4
-3.2
phosphoglucosamine mutase
compare
MMJJ
_RS00060
-2.4
-18.2
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS00040
-2.4
-9.6
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS05190
-2.4
-6.8
gamma carbonic anhydrase family protein
compare
MMJJ
_RS06220
-2.3
-5.3
polyamine aminopropyltransferase
compare
MMJJ
_RS07995
-2.3
-6.5
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS03150
-2.3
-7.2
2-phospho-L-lactate transferase
compare
MMJJ
_RS06835
-2.3
-11.9
4Fe-4S binding protein
compare
MMJJ
_RS00035
-2.3
-15.7
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS02055
-2.3
-12.1
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS05295
-2.3
-10.6
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS00070
-2.3
-3.6
CooT family nickel-binding protein
compare
MMJJ
_RS05155
-2.3
-8.0
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS00075
-2.3
-10.6
AAA family ATPase
compare
MMJJ
_RS07470
-2.3
-2.9
50S ribosome-binding GTPase
compare
MMJJ
_RS07640
-2.3
-17.9
cache domain-containing protein
compare
MMJJ
_RS06180
-2.3
-2.8
tryptophan--tRNA ligase
compare
MMJJ
_RS04110
-2.2
-5.4
hypothetical protein
compare
MMJJ
_RS07950
-2.2
-3.7
4Fe-4S binding protein
compare
MMJJ
_RS03815
-2.2
-2.8
nascent polypeptide-associated complex protein
compare
MMJJ
_RS07635
-2.2
-11.8
response regulator transcription factor
compare
MMJJ
_RS08535
-2.2
-3.7
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS00275
-2.2
-2.9
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03845
-2.2
-3.7
translation initiation factor IF-2
compare
MMJJ
_RS01865
-2.2
-8.7
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS01475
-2.2
-2.7
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS00055
-2.2
-10.3
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS03630
-2.2
-11.8
AMP phosphorylase
compare
MMJJ
_RS04670
-2.2
-5.8
DUF2117 domain-containing protein
compare
MMJJ
_RS01415
-2.2
-3.3
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS00080
-2.2
-11.8
DUF166 domain-containing protein
compare
MMJJ
_RS06015
-2.1
-11.7
Na(+)/H(+) antiporter subunit B
compare
MMJJ
_RS09055
-2.1
-11.5
NFACT family protein
compare
MMJJ
_RS06185
-2.1
-5.0
cobalamin biosynthesis protein
compare
MMJJ
_RS06730
-2.1
-6.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07415
-2.1
-3.7
polyprenyl diphosphate synthase
compare
MMJJ
_RS04980
-2.1
-5.7
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS08065
-2.1
-3.4
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS08155
-2.1
-4.1
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS06750
-2.1
-3.2
homoaconitase large subunit
compare
MMJJ
_RS03060
-2.1
-2.7
methanogenesis marker 7 protein
compare
MMJJ
_RS05610
-2.1
-3.5
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS06380
-2.1
-4.7
signal recognition particle protein Srp54
compare
MMJJ
_RS07650
-2.1
-15.2
formate/nitrite transporter family protein
compare
MMJJ
_RS07370
-2.1
-3.8
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS06805
-2.1
-3.4
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS05360
-2.0
-6.8
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS07725
-2.0
-7.1
DNA primase DnaG
compare
MMJJ
_RS00530
-2.0
-12.2
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS03800
-2.0
-9.3
aldolase
compare
MMJJ
_RS05375
-2.0
-14.1
radical SAM protein
compare
MMJJ
_RS03995
-2.0
-5.8
PHP domain-containing protein
compare
MMJJ
_RS08480
-2.0
-8.2
hydroxyethylthiazole kinase
compare
MMJJ
_RS05590
-2.0
-2.0
homoserine dehydrogenase
compare
MMJJ
_RS03005
-2.0
-3.9
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS09175
-2.0
-2.2
anthranilate synthase component I
compare
MMJJ
_RS01830
-2.0
-3.1
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS06175
-2.0
-3.4
DUF1743 domain-containing protein
compare
MMJJ
_RS03160
-2.0
-13.8
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS00265
-2.0
-6.7
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS06865
-1.9
-2.4
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS08585
-1.9
-9.2
M42 family metallopeptidase
compare
MMJJ
_RS07000
-1.9
-1.9
TrkH family potassium uptake protein
compare
MMJJ
_RS01810
-1.9
-3.1
methyl coenzyme M reductase system, component A2
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments