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Experiment set3IT038 for
Methanococcus maripaludis JJ
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formate McAA folic acid dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.1
10.4
hypothetical protein
compare
MMJJ
_RS03725
+1.0
2.7
sulfurtransferase TusA family protein
compare
MMJJ
_RS04005
+0.9
6.1
acetate--CoA ligase family protein
compare
MMJJ
_RS08830
+0.8
3.2
hypothetical protein
compare
MMJJ
_RS04545
+0.7
3.3
PadR family transcriptional regulator
compare
MMJJ
_RS03835
+0.7
3.3
DUF504 domain-containing protein
compare
MMJJ
_RS07235
+0.6
5.2
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS07240
+0.6
5.3
MBL fold metallo-hydrolase
compare
MMJJ
_RS07225
+0.6
4.0
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS08935
+0.6
0.9
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS06680
+0.6
3.6
DUF366 family protein
compare
MMJJ
_RS05685
+0.6
3.4
class III signal peptide-containing protein
compare
MMJJ
_RS05280
+0.6
0.8
hypothetical protein
compare
MMJJ
_RS06505
+0.6
2.7
prephenate dehydratase
compare
MMJJ
_RS07220
+0.6
4.2
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS06275
+0.5
2.3
hypothetical protein
compare
MMJJ
_RS07025
+0.5
3.1
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS07185
+0.5
2.3
DUF371 domain-containing protein
compare
MMJJ
_RS03805
+0.5
1.5
hypothetical protein
compare
MMJJ
_RS06500
+0.5
3.6
class I SAM-dependent methyltransferase
compare
MMJJ
_RS04955
+0.5
3.1
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS06460
+0.5
3.2
cytochrome c
compare
MMJJ
_RS05040
+0.5
3.3
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS01855
+0.5
3.5
MBL fold metallo-hydrolase
compare
MMJJ
_RS06675
+0.5
3.7
TIGR01212 family radical SAM protein
compare
MMJJ
_RS06770
+0.5
3.9
hypothetical protein
compare
MMJJ
_RS07680
+0.4
2.9
glucose-6-phosphate isomerase
compare
MMJJ
_RS07920
+0.4
3.2
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS05975
+0.4
3.1
sulfurtransferase TusA family protein
compare
MMJJ
_RS07230
+0.4
2.9
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS06640
+0.4
3.0
YfcE family phosphodiesterase
compare
MMJJ
_RS06190
+0.4
3.1
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS03605
+0.4
2.2
TIGR00297 family protein
compare
MMJJ
_RS06585
+0.4
2.9
alanine racemase
compare
MMJJ
_RS04105
+0.4
3.3
prepilin peptidase
compare
MMJJ
_RS06735
+0.4
2.7
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS02270
+0.4
1.5
HEPN domain-containing protein
compare
MMJJ
_RS06440
+0.4
2.5
DUF4870 domain-containing protein
compare
MMJJ
_RS01670
+0.4
1.9
hypothetical protein
compare
MMJJ
_RS00500
+0.4
1.9
GNAT family N-acetyltransferase
compare
MMJJ
_RS06950
+0.4
2.7
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS07795
+0.4
2.1
cupin domain-containing protein
compare
MMJJ
_RS06535
+0.4
3.1
UPF0104 family protein
compare
MMJJ
_RS09300
+0.4
1.2
hypothetical protein
compare
MMJJ
_RS06800
+0.4
2.0
prefoldin subunit alpha
compare
MMJJ
_RS05525
+0.4
2.2
GTP-binding protein
compare
MMJJ
_RS03395
+0.4
1.3
hypothetical protein
compare
MMJJ
_RS06765
+0.4
3.1
hypothetical protein
compare
MMJJ
_RS06685
+0.4
3.2
S-layer protein
compare
MMJJ
_RS06740
+0.4
1.9
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS05700
+0.4
2.4
metallophosphoesterase
compare
MMJJ
_RS08100
+0.3
2.1
hypothetical protein
compare
MMJJ
_RS06090
+0.3
2.3
hypothetical protein
compare
MMJJ
_RS07010
+0.3
2.2
preprotein translocase subunit Sec61beta
compare
MMJJ
_RS07210
+0.3
2.6
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS08455
+0.3
1.5
tetratricopeptide repeat protein
compare
MMJJ
_RS07260
+0.3
2.3
PspC domain-containing protein
compare
MMJJ
_RS06210
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS01010
+0.3
3.1
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS07215
+0.3
2.7
TIGR00341 family protein
compare
MMJJ
_RS06810
+0.3
2.5
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS00150
+0.3
2.0
DUF2180 family protein
compare
MMJJ
_RS06960
+0.3
2.9
CAP domain-containing protein
compare
MMJJ
_RS07935
+0.3
0.3
protein fwdD
compare
MMJJ
_RS06515
+0.3
2.4
ribonuclease III
compare
MMJJ
_RS03410
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS07825
+0.3
1.7
YciI family protein
compare
MMJJ
_RS06120
+0.3
2.2
DUF4013 domain-containing protein
compare
MMJJ
_RS06085
+0.3
1.4
proteasome assembly chaperone family protein
compare
MMJJ
_RS07765
+0.3
1.5
DMT family protein
compare
MMJJ
_RS08160
+0.3
1.9
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMJJ
_RS07480
+0.3
2.3
FAD-dependent oxidoreductase
compare
MMJJ
_RS08390
+0.3
1.0
carboxymuconolactone decarboxylase family protein
compare
MMJJ
_RS07800
+0.3
2.3
AMP-binding protein
compare
MMJJ
_RS07835
+0.3
2.2
UPF0489 family protein
compare
MMJJ
_RS08525
+0.3
1.5
peptidylprolyl isomerase
compare
MMJJ
_RS08515
+0.3
1.1
secondary thiamine-phosphate synthase enzyme YjbQ
compare
MMJJ
_RS03285
+0.3
1.7
gamma-glutamylcyclotransferase
compare
MMJJ
_RS07915
+0.3
1.6
CBS domain-containing protein
compare
MMJJ
_RS05915
+0.3
1.2
multiprotein bridging factor aMBF1
compare
MMJJ
_RS06580
+0.3
2.1
alanine dehydrogenase
compare
MMJJ
_RS01955
+0.3
2.4
hypothetical protein
compare
MMJJ
_RS06385
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS06495
+0.3
0.6
hypothetical protein
compare
MMJJ
_RS01825
+0.3
1.7
DNA repair and recombination protein RadB
compare
MMJJ
_RS04350
+0.3
1.3
hypothetical protein
compare
MMJJ
_RS07905
+0.3
1.9
DUF89 domain-containing protein
compare
MMJJ
_RS07815
+0.3
1.9
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS05355
+0.3
1.7
DUF2121 domain-containing protein
compare
MMJJ
_RS05980
+0.3
1.9
DUF5400 domain-containing protein
compare
MMJJ
_RS05115
+0.3
1.1
P-II family nitrogen regulator
compare
MMJJ
_RS06455
+0.3
2.0
YeeE/YedE family protein
compare
MMJJ
_RS03575
+0.3
1.2
NUDIX hydrolase
compare
MMJJ
_RS06710
+0.3
2.2
TldD/PmbA family protein
compare
MMJJ
_RS07820
+0.3
1.9
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS06205
+0.2
1.8
EamA family transporter
compare
MMJJ
_RS06550
+0.2
1.9
ABC transporter permease
compare
MMJJ
_RS07200
+0.2
2.0
MFS transporter
compare
MMJJ
_RS05405
+0.2
1.9
DNA cytosine methyltransferase
compare
MMJJ
_RS05520
+0.2
1.9
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS09360
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS06745
+0.2
1.4
energy-coupling factor ABC transporter permease
compare
MMJJ
_RS07595
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS01745
+0.2
1.1
metal-dependent transcriptional regulator
compare
MMJJ
_RS09295
+0.2
0.3
hypothetical protein
compare
MMJJ
_RS05200
+0.2
1.9
TIGR04013 family B12-binding domain/radical SAM domain-containing protein
compare
MMJJ
_RS06790
+0.2
1.9
nucleotidyltransferase family protein
compare
MMJJ
_RS02230
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS08305
+0.2
1.4
peroxiredoxin
compare
MMJJ
_RS07270
+0.2
1.6
ribonuclease HII
compare
MMJJ
_RS04830
+0.2
1.5
zinc dependent phospholipase C family protein
compare
MMJJ
_RS04215
+0.2
1.9
DMT family transporter
compare
MMJJ
_RS00745
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06285
+0.2
1.3
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS05970
+0.2
0.7
MJ0307 family thioredoxin
compare
MMJJ
_RS07810
+0.2
1.5
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS09325
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS03850
+0.2
1.0
nucleoside-diphosphate kinase
compare
MMJJ
_RS03905
+0.2
1.5
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06280
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS08880
+0.2
1.3
IMPACT family protein
compare
MMJJ
_RS01845
+0.2
1.7
acetolactate decarboxylase
compare
MMJJ
_RS06445
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS09365
+0.2
0.6
hypothetical protein
compare
MMJJ
_RS07685
+0.2
1.8
glycogen/starch synthase
compare
MMJJ
_RS00730
+0.2
1.3
peptide-methionine (S)-S-oxide reductase MsrA
compare
MMJJ
_RS09230
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS01790
+0.2
1.5
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS01095
+0.2
1.6
site-specific integrase
compare
MMJJ
_RS09065
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS05335
+0.2
1.3
heavy metal-binding domain-containing protein
compare
MMJJ
_RS04390
+0.2
1.7
rhomboid family intramembrane serine protease
compare
MMJJ
_RS06470
+0.2
1.5
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS07445
+0.2
1.5
RlmF-related methyltransferase
compare
MMJJ
_RS05690
+0.2
1.9
hypothetical protein
compare
MMJJ
_RS07175
+0.2
1.6
DEAD/DEAH box helicase
compare
MMJJ
_RS09205
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS06450
+0.2
1.5
DUF3343 domain-containing protein
compare
MMJJ
_RS03040
+0.2
1.4
lactate utilization protein
compare
MMJJ
_RS01970
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS06540
+0.2
0.8
DUF2120 domain-containing protein
compare
MMJJ
_RS05715
+0.2
1.4
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS07985
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS02340
+0.2
1.0
SAM-dependent methyltransferase
compare
MMJJ
_RS06430
+0.2
1.2
haloacid dehalogenase
compare
MMJJ
_RS07385
+0.2
1.4
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS05960
+0.2
1.3
DUF169 domain-containing protein
compare
MMJJ
_RS00145
+0.2
1.4
aquaporin family protein
compare
MMJJ
_RS05500
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS03370
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS07495
+0.2
1.1
4Fe-4S binding protein
compare
MMJJ
_RS05990
+0.2
1.2
phosphatase PAP2 family protein
compare
MMJJ
_RS02155
+0.2
1.3
DMT family transporter
compare
MMJJ
_RS03735
+0.2
1.3
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS07695
+0.2
1.5
glycoside hydrolase family 15 protein
compare
MMJJ
_RS05350
+0.2
0.9
DUF192 domain-containing protein
compare
MMJJ
_RS05410
+0.2
1.1
RecB-family nuclease
compare
MMJJ
_RS08350
+0.2
1.5
heavy metal translocating P-type ATPase
compare
MMJJ
_RS04825
+0.2
1.4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
compare
MMJJ
_RS05605
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS05340
+0.2
1.4
AAA family ATPase
compare
MMJJ
_RS03375
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS09005
+0.2
1.5
N-6 DNA methylase
compare
MMJJ
_RS02665
+0.2
0.6
methyl-accepting chemotaxis protein
compare
MMJJ
_RS01385
+0.2
1.3
PadR family transcriptional regulator
compare
MMJJ
_RS02290
+0.2
1.2
MarR family transcriptional regulator
compare
MMJJ
_RS06665
+0.2
0.8
DUF3236 domain-containing protein
compare
MMJJ
_RS06100
+0.2
1.2
rubrerythrin
compare
MMJJ
_RS07005
+0.2
0.7
transcription factor S
compare
MMJJ
_RS06590
+0.2
1.3
sodium:alanine symporter family protein
compare
MMJJ
_RS06520
+0.2
1.3
TldD/PmbA family protein
compare
MMJJ
_RS09405
+0.2
0.4
hypothetical protein
compare
MMJJ
_RS07280
+0.2
0.9
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS07830
+0.2
1.1
DUF1786 domain-containing protein
compare
MMJJ
_RS04300
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS06235
+0.2
1.3
IGHMBP2 family helicase
compare
MMJJ
_RS04850
+0.2
1.0
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS07855
+0.2
1.1
YkgJ family cysteine cluster protein
compare
MMJJ
_RS05885
+0.2
1.4
tungstate ABC transporter substrate-binding protein WtpA
compare
MMJJ
_RS07450
+0.2
0.8
hypothetical protein
compare
MMJJ
_RS07910
+0.2
1.0
CBS domain-containing protein
compare
MMJJ
_RS01785
+0.2
0.3
50S ribosomal protein L14e
compare
MMJJ
_RS00155
+0.2
1.3
DUF2193 domain-containing protein
compare
MMJJ
_RS00845
+0.2
1.0
hypothetical protein
compare
MMJJ
_RS08485
+0.1
0.7
Lrp/AsnC family transcriptional regulator
compare
MMJJ
_RS07890
+0.1
0.9
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS09145
+0.1
0.9
exodeoxyribonuclease III
compare
MMJJ
_RS01320
+0.1
1.2
indolepyruvate ferredoxin oxidoreductase subunit alpha
compare
MMJJ
_RS09380
+0.1
0.5
hypothetical protein
compare
MMJJ
_RS02160
+0.1
0.9
amino acid ABC transporter permease
compare
MMJJ
_RS00815
+0.1
1.2
ASKHA domain-containing protein
compare
MMJJ
_RS07255
+0.1
1.2
hypothetical protein
compare
MMJJ
_RS02240
+0.1
0.7
CGGC domain-containing protein
compare
MMJJ
_RS01300
+0.1
1.0
MarR family transcriptional regulator
compare
MMJJ
_RS00400
+0.1
0.4
tautomerase family protein
compare
MMJJ
_RS00705
+0.1
1.0
nitrogenase iron protein
compare
MMJJ
_RS04500
+0.1
1.0
hypothetical protein
compare
MMJJ
_RS04340
+0.1
0.4
hypothetical protein
compare
MMJJ
_RS05585
+0.1
0.9
hypothetical protein
compare
MMJJ
_RS05390
+0.1
1.1
tRNA pseudouridine(13) synthase TruD
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments