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Experiment set3IT037 for
Methanococcus maripaludis JJ
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formate McAA folic acid dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.2
-23.5
hypothetical protein
compare
MMJJ
_RS00570
-6.1
-2.9
ribonuclease P
compare
MMJJ
_RS04050
-6.0
-2.8
dihydroneopterin aldolase family protein
compare
MMJJ
_RS00275
-5.6
-3.4
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS04485
-5.4
-12.1
riboflavin synthase
compare
MMJJ
_RS04200
-5.2
-8.9
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS03895
-5.0
-5.4
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS06240
-4.9
-4.4
dihydropteroate synthase-like protein
compare
MMJJ
_RS06860
-4.7
-5.6
hypothetical protein
compare
MMJJ
_RS00270
-4.6
-5.4
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS03875
-4.6
-5.7
CBS domain-containing protein
compare
MMJJ
_RS05490
-4.5
-3.1
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS04475
-4.3
-6.4
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS00210
-4.3
-3.4
DUF530 family protein
compare
MMJJ
_RS08660
-4.3
-4.1
acetylornithine transaminase
compare
MMJJ
_RS03760
-4.3
-5.8
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS00355
-4.2
-3.9
ribonuclease P protein component 4
compare
MMJJ
_RS05450
-4.2
-16.8
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS01935
-4.2
-5.6
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS05995
-4.2
-3.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03865
-4.1
-1.8
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS03840
-4.1
-6.1
DHH family phosphoesterase
compare
MMJJ
_RS06490
-4.1
-4.5
methanogenesis marker 2 protein
compare
MMJJ
_RS06840
-4.1
-4.8
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS06625
-4.1
-3.3
pyruvate synthase subunit PorB
compare
MMJJ
_RS08020
-4.0
-9.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS05650
-4.0
-4.4
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS01870
-4.0
-3.3
methanogenesis marker 15 protein
compare
MMJJ
_RS00215
-3.9
-3.5
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS01360
-3.9
-3.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS07950
-3.9
-5.3
4Fe-4S binding protein
compare
MMJJ
_RS07000
-3.9
-2.9
TrkH family potassium uptake protein
compare
MMJJ
_RS04800
-3.8
-8.6
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS03580
-3.8
-5.0
TIGR00303 family protein
compare
MMJJ
_RS08250
-3.8
-9.7
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS00580
-3.8
-2.7
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS07380
-3.8
-11.5
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS07665
-3.8
-23.0
formate dehydrogenase subunit alpha
compare
MMJJ
_RS06390
-3.8
-3.2
NADPH-dependent F420 reductase
compare
MMJJ
_RS05535
-3.8
-14.8
hypothetical protein
compare
MMJJ
_RS01755
-3.7
-3.4
ferrous iron transport protein B
compare
MMJJ
_RS06695
-3.7
-4.9
amidohydrolase
compare
MMJJ
_RS02045
-3.7
-3.6
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS03110
-3.7
-5.2
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS05930
-3.7
-3.1
cell division protein SepF
compare
MMJJ
_RS05575
-3.7
-4.9
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS02935
-3.6
-5.0
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS03615
-3.6
-4.5
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS04685
-3.6
-11.0
carbamoyltransferase HypF
compare
MMJJ
_RS03200
-3.6
-3.7
uroporphyrinogen-III synthase
compare
MMJJ
_RS03055
-3.6
-4.4
hypothetical protein
compare
MMJJ
_RS03670
-3.6
-6.7
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS06915
-3.6
-15.3
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08320
-3.6
-3.9
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS08625
-3.6
-9.3
magnesium/cobalt transporter CorA
compare
MMJJ
_RS05260
-3.6
-8.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS07470
-3.6
-2.9
50S ribosome-binding GTPase
compare
MMJJ
_RS07655
-3.5
-16.1
hypothetical protein
compare
MMJJ
_RS07670
-3.5
-19.2
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS03820
-3.5
-5.7
hydrogenase formation protein HypD
compare
MMJJ
_RS05330
-3.4
-3.9
DNA polymerase II large subunit
compare
MMJJ
_RS06930
-3.4
-4.3
type II methionyl aminopeptidase
compare
MMJJ
_RS05070
-3.4
-3.7
DNA primase catalytic subunit PriS
compare
MMJJ
_RS06180
-3.4
-4.5
tryptophan--tRNA ligase
compare
MMJJ
_RS03005
-3.3
-5.5
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03125
-3.3
-7.0
GMC oxidoreductase
compare
MMJJ
_RS01750
-3.3
-3.7
ferrous iron transport protein A
compare
MMJJ
_RS06255
-3.3
-9.6
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS08080
-3.3
-13.5
TIGR00300 family protein
compare
MMJJ
_RS02090
-3.3
-6.4
tyramine--L-glutamate ligase
compare
MMJJ
_RS06725
-3.3
-14.5
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS06040
-3.3
-6.3
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS04155
-3.3
-7.5
hypothetical protein
compare
MMJJ
_RS06175
-3.3
-3.9
DUF1743 domain-containing protein
compare
MMJJ
_RS07785
-3.2
-3.7
fumarate reductase subunit A
compare
MMJJ
_RS03785
-3.2
-4.3
hypothetical protein
compare
MMJJ
_RS02275
-3.2
-5.4
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03150
-3.2
-8.0
2-phospho-L-lactate transferase
compare
MMJJ
_RS06110
-3.2
-3.3
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS07350
-3.2
-5.3
4Fe-4S binding protein
compare
MMJJ
_RS06785
-3.2
-9.0
RNA ligase partner protein
compare
MMJJ
_RS05620
-3.2
-6.0
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS08000
-3.2
-10.1
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS05065
-3.1
-5.6
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS06875
-3.1
-3.9
hypothetical protein
compare
MMJJ
_RS04790
-3.1
-5.1
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS07360
-3.1
-2.1
TIGR00269 family protein
compare
MMJJ
_RS07410
-3.1
-4.7
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS08055
-3.1
-7.0
methanogenesis marker 14 protein
compare
MMJJ
_RS03295
-3.0
-15.5
PHP domain-containing protein
compare
MMJJ
_RS05225
-3.0
-2.2
Gar1/Naf1 family protein
compare
MMJJ
_RS08005
-3.0
-18.6
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS06250
-3.0
-3.6
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS03115
-3.0
-10.0
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS08330
-3.0
-3.9
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS05935
-3.0
-2.8
Era-like GTP-binding protein
compare
MMJJ
_RS00560
-3.0
-6.0
homoisocitrate dehydrogenase
compare
MMJJ
_RS06835
-3.0
-14.4
4Fe-4S binding protein
compare
MMJJ
_RS01600
-2.9
-3.7
radical SAM protein
compare
MMJJ
_RS06155
-2.9
-5.4
phosphatidylglycerophosphatase A
compare
MMJJ
_RS08535
-2.9
-4.1
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS07660
-2.9
-11.6
carbonic anhydrase
compare
MMJJ
_RS06485
-2.9
-4.1
phosphoglycerate kinase
compare
MMJJ
_RS04970
-2.9
-2.2
DUF655 domain-containing protein
compare
MMJJ
_RS09175
-2.9
-2.1
anthranilate synthase component I
compare
MMJJ
_RS01865
-2.8
-6.3
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS00070
-2.8
-5.0
CooT family nickel-binding protein
compare
MMJJ
_RS03095
-2.8
-3.8
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS02920
-2.8
-2.6
30S ribosomal protein S27ae
compare
MMJJ
_RS00040
-2.8
-12.2
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS01565
-2.8
-7.9
TIGR00267 family protein
compare
MMJJ
_RS05810
-2.8
-6.9
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS05190
-2.8
-9.2
gamma carbonic anhydrase family protein
compare
MMJJ
_RS05610
-2.7
-4.9
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS03065
-2.7
-12.2
CBS domain-containing protein
compare
MMJJ
_RS00050
-2.7
-12.3
AAA family ATPase
compare
MMJJ
_RS07725
-2.7
-7.0
DNA primase DnaG
compare
MMJJ
_RS08340
-2.7
-5.3
archaeoflavoprotein AfpA
compare
MMJJ
_RS03270
-2.7
-2.6
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS04675
-2.7
-8.6
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS04995
-2.7
-5.7
Tfx family DNA-binding protein
compare
MMJJ
_RS03620
-2.6
-5.6
DUF2097 domain-containing protein
compare
MMJJ
_RS05445
-2.6
-2.0
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS01355
-2.6
-4.3
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS00125
-2.6
-3.3
KEOPS complex subunit Cgi121
compare
MMJJ
_RS00600
-2.6
-3.3
hydroxymethylbilane synthase
compare
MMJJ
_RS08095
-2.6
-6.1
cobyric acid synthase CobQ
compare
MMJJ
_RS06750
-2.6
-3.7
homoaconitase large subunit
compare
MMJJ
_RS00060
-2.6
-16.3
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS06220
-2.6
-6.8
polyamine aminopropyltransferase
compare
MMJJ
_RS00065
-2.5
-15.6
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS05765
-2.5
-1.8
flagellar protein E
compare
MMJJ
_RS03830
-2.5
-8.2
CBS domain-containing protein
compare
MMJJ
_RS06905
-2.5
-3.0
hypothetical protein
compare
MMJJ
_RS06910
-2.5
-2.4
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS00035
-2.5
-16.3
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS05360
-2.5
-6.4
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS03660
-2.5
-4.2
DUF447 family protein
compare
MMJJ
_RS06215
-2.5
-5.1
agmatinase
compare
MMJJ
_RS04975
-2.4
-2.6
glycosyltransferase family 4 protein
compare
MMJJ
_RS04520
-2.4
-6.3
coenzyme F430 synthase
compare
MMJJ
_RS01345
-2.4
-5.8
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS05655
-2.4
-6.8
HisA/HisF family protein
compare
MMJJ
_RS03800
-2.4
-11.5
aldolase
compare
MMJJ
_RS07370
-2.4
-5.0
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS01690
-2.4
-4.5
methanogenesis marker 12 protein
compare
MMJJ
_RS07245
-2.4
-3.8
amidohydrolase family protein
compare
MMJJ
_RS00045
-2.4
-14.6
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS03190
-2.4
-2.8
phosphopyruvate hydratase
compare
MMJJ
_RS07345
-2.4
-5.6
homocysteine biosynthesis protein
compare
MMJJ
_RS00075
-2.4
-11.4
AAA family ATPase
compare
MMJJ
_RS01200
-2.4
-3.7
PRC-barrel domain-containing protein
compare
MMJJ
_RS06510
-2.4
-3.3
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS05295
-2.4
-9.7
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS03630
-2.3
-12.1
AMP phosphorylase
compare
MMJJ
_RS06185
-2.3
-6.0
cobalamin biosynthesis protein
compare
MMJJ
_RS07275
-2.3
-4.0
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS08840
-2.3
-5.0
calcium/sodium antiporter
compare
MMJJ
_RS00205
-2.3
-5.8
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS05950
-2.3
-3.7
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS00520
-2.3
-5.6
PDGLE domain-containing protein
compare
MMJJ
_RS05375
-2.3
-14.6
radical SAM protein
compare
MMJJ
_RS06225
-2.3
-3.0
adenosylmethionine decarboxylase
compare
MMJJ
_RS06375
-2.3
-5.1
UbiX family flavin prenyltransferase
compare
MMJJ
_RS03765
-2.3
-7.2
hypothetical protein
compare
MMJJ
_RS00055
-2.2
-9.8
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS04655
-2.2
-6.2
FAD-dependent oxidoreductase
compare
MMJJ
_RS07995
-2.2
-6.5
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS07840
-2.2
-2.2
Glu-tRNA(Gln) amidotransferase subunit GatD
compare
MMJJ
_RS00360
-2.2
-3.1
adenosylhomocysteinase
compare
MMJJ
_RS00530
-2.2
-10.5
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS08325
-2.2
-2.7
glycosyltransferase family 2 protein
compare
MMJJ
_RS00080
-2.2
-13.1
DUF166 domain-containing protein
compare
MMJJ
_RS08620
-2.2
-3.5
DUF373 family protein
compare
MMJJ
_RS04700
-2.2
-5.8
deoxyhypusine synthase
compare
MMJJ
_RS07155
-2.1
-7.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS05155
-2.1
-6.5
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS09055
-2.1
-8.7
NFACT family protein
compare
MMJJ
_RS02040
-2.1
-2.1
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS07640
-2.1
-16.0
cache domain-containing protein
compare
MMJJ
_RS00425
-2.1
-3.7
hypothetical protein
compare
MMJJ
_RS06805
-2.1
-3.4
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS03845
-2.1
-4.1
translation initiation factor IF-2
compare
MMJJ
_RS02055
-2.1
-11.5
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS03225
-2.1
-3.9
4Fe-4S binding protein
compare
MMJJ
_RS07720
-2.1
-3.0
UPF0058 family protein
compare
MMJJ
_RS00195
-2.1
-4.0
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS07635
-2.0
-11.4
response regulator transcription factor
compare
MMJJ
_RS06050
-2.0
-9.3
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS00265
-2.0
-6.9
TIGR02253 family HAD-type hydrolase
compare
MMJJ
_RS07980
-2.0
-11.2
biotin synthase BioB
compare
MMJJ
_RS07875
-2.0
-2.0
FAD-dependent oxidoreductase
compare
MMJJ
_RS04110
-2.0
-4.6
hypothetical protein
compare
MMJJ
_RS04145
-2.0
-10.3
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS03815
-2.0
-2.8
nascent polypeptide-associated complex protein
compare
MMJJ
_RS04595
-2.0
-4.0
hypothetical protein
compare
MMJJ
_RS04985
-2.0
-3.5
glutamyl-tRNA reductase
compare
MMJJ
_RS04730
-1.9
-2.8
tyrosine decarboxylase MfnA
compare
MMJJ
_RS07945
-1.9
-2.3
4Fe-4S binding protein
compare
MMJJ
_RS08795
-1.9
-2.4
phosphoglucosamine mutase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments