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Experiment set3IT036 for
Methanococcus maripaludis JJ
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formate McAA biotin dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.4
-22.4
hypothetical protein
compare
MMJJ
_RS06695
-5.3
-3.6
amidohydrolase
compare
MMJJ
_RS02920
-5.2
-3.0
30S ribosomal protein S27ae
compare
MMJJ
_RS06860
-5.1
-5.8
hypothetical protein
compare
MMJJ
_RS00270
-5.1
-3.5
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS03580
-4.9
-3.4
TIGR00303 family protein
compare
MMJJ
_RS07360
-4.9
-2.5
TIGR00269 family protein
compare
MMJJ
_RS03895
-4.8
-5.1
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS00210
-4.8
-3.1
DUF530 family protein
compare
MMJJ
_RS05450
-4.8
-20.2
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS01935
-4.5
-6.1
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS00570
-4.5
-2.8
ribonuclease P
compare
MMJJ
_RS00215
-4.4
-3.0
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS00450
-4.4
-2.6
DUF126 domain-containing protein
compare
MMJJ
_RS01870
-4.4
-2.8
methanogenesis marker 15 protein
compare
MMJJ
_RS04200
-4.3
-7.7
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS06625
-4.2
-3.3
pyruvate synthase subunit PorB
compare
MMJJ
_RS03615
-4.2
-4.7
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS05610
-4.2
-4.1
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS04800
-4.2
-8.0
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS05490
-4.2
-2.9
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS05950
-4.1
-4.0
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS02090
-4.1
-7.0
tyramine--L-glutamate ligase
compare
MMJJ
_RS00580
-4.1
-2.7
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS05650
-4.1
-3.9
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS03815
-4.1
-3.0
nascent polypeptide-associated complex protein
compare
MMJJ
_RS08020
-4.0
-9.5
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03840
-3.9
-4.6
DHH family phosphoesterase
compare
MMJJ
_RS06910
-3.9
-3.4
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS00355
-3.9
-3.7
ribonuclease P protein component 4
compare
MMJJ
_RS01750
-3.8
-4.3
ferrous iron transport protein A
compare
MMJJ
_RS07670
-3.8
-16.6
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS00600
-3.8
-4.0
hydroxymethylbilane synthase
compare
MMJJ
_RS07665
-3.8
-22.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS05535
-3.7
-14.8
hypothetical protein
compare
MMJJ
_RS06255
-3.7
-7.5
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS06725
-3.7
-13.5
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS03110
-3.7
-5.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS08250
-3.7
-8.5
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS02275
-3.7
-5.1
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03200
-3.6
-3.2
uroporphyrinogen-III synthase
compare
MMJJ
_RS03005
-3.6
-4.8
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS02045
-3.6
-4.6
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS04995
-3.5
-7.5
Tfx family DNA-binding protein
compare
MMJJ
_RS03670
-3.5
-6.6
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS03270
-3.5
-3.4
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS01810
-3.4
-2.0
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS04730
-3.4
-3.9
tyrosine decarboxylase MfnA
compare
MMJJ
_RS00275
-3.4
-3.8
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03660
-3.4
-5.4
DUF447 family protein
compare
MMJJ
_RS04155
-3.4
-8.6
hypothetical protein
compare
MMJJ
_RS04685
-3.4
-11.6
carbamoyltransferase HypF
compare
MMJJ
_RS05575
-3.3
-4.3
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS01755
-3.3
-3.2
ferrous iron transport protein B
compare
MMJJ
_RS03820
-3.3
-5.3
hydrogenase formation protein HypD
compare
MMJJ
_RS07660
-3.3
-12.3
carbonic anhydrase
compare
MMJJ
_RS07380
-3.3
-9.5
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS07350
-3.3
-4.5
4Fe-4S binding protein
compare
MMJJ
_RS05330
-3.3
-3.1
DNA polymerase II large subunit
compare
MMJJ
_RS01415
-3.3
-3.6
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS05445
-3.2
-2.7
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS07945
-3.2
-4.2
4Fe-4S binding protein
compare
MMJJ
_RS08000
-3.2
-10.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS07655
-3.2
-15.2
hypothetical protein
compare
MMJJ
_RS07000
-3.2
-2.2
TrkH family potassium uptake protein
compare
MMJJ
_RS06155
-3.1
-7.1
phosphatidylglycerophosphatase A
compare
MMJJ
_RS08005
-3.1
-17.3
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS09190
-3.1
-2.9
tryptophan synthase subunit beta
compare
MMJJ
_RS04790
-3.1
-5.6
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS08625
-3.1
-8.6
magnesium/cobalt transporter CorA
compare
MMJJ
_RS08055
-3.1
-6.6
methanogenesis marker 14 protein
compare
MMJJ
_RS03190
-3.1
-3.5
phosphopyruvate hydratase
compare
MMJJ
_RS08330
-3.0
-4.8
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS04985
-3.0
-5.3
glutamyl-tRNA reductase
compare
MMJJ
_RS02040
-3.0
-2.0
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS08095
-3.0
-5.0
cobyric acid synthase CobQ
compare
MMJJ
_RS03785
-3.0
-3.1
hypothetical protein
compare
MMJJ
_RS06485
-3.0
-4.3
phosphoglycerate kinase
compare
MMJJ
_RS03150
-2.9
-8.1
2-phospho-L-lactate transferase
compare
MMJJ
_RS08080
-2.9
-10.1
TIGR00300 family protein
compare
MMJJ
_RS06915
-2.9
-13.6
helix-turn-helix domain-containing protein
compare
MMJJ
_RS01475
-2.9
-2.9
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS08320
-2.9
-2.9
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS01360
-2.9
-3.3
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS06175
-2.9
-3.7
DUF1743 domain-containing protein
compare
MMJJ
_RS05260
-2.9
-6.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS06490
-2.8
-4.1
methanogenesis marker 2 protein
compare
MMJJ
_RS00360
-2.8
-3.6
adenosylhomocysteinase
compare
MMJJ
_RS01565
-2.8
-7.3
TIGR00267 family protein
compare
MMJJ
_RS05065
-2.8
-4.1
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS06270
-2.8
-8.9
dethiobiotin synthase
compare
MMJJ
_RS00520
-2.8
-5.8
PDGLE domain-containing protein
compare
MMJJ
_RS04970
-2.8
-2.5
DUF655 domain-containing protein
compare
MMJJ
_RS00205
-2.8
-6.2
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS08340
-2.8
-5.3
archaeoflavoprotein AfpA
compare
MMJJ
_RS03125
-2.7
-4.9
GMC oxidoreductase
compare
MMJJ
_RS06185
-2.7
-7.3
cobalamin biosynthesis protein
compare
MMJJ
_RS05415
-2.7
-2.4
hypothetical protein
compare
MMJJ
_RS03620
-2.7
-5.6
DUF2097 domain-containing protein
compare
MMJJ
_RS00125
-2.7
-3.5
KEOPS complex subunit Cgi121
compare
MMJJ
_RS03295
-2.7
-15.2
PHP domain-containing protein
compare
MMJJ
_RS08850
-2.6
-3.0
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS06785
-2.6
-7.5
RNA ligase partner protein
compare
MMJJ
_RS08855
-2.6
-4.5
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS01600
-2.6
-4.0
radical SAM protein
compare
MMJJ
_RS06705
-2.6
-6.3
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS09375
-2.6
-2.0
hypothetical protein
compare
MMJJ
_RS05655
-2.6
-6.3
HisA/HisF family protein
compare
MMJJ
_RS05380
-2.6
-1.8
hypothetical protein
compare
MMJJ
_RS05225
-2.6
-2.1
Gar1/Naf1 family protein
compare
MMJJ
_RS06110
-2.6
-3.0
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS03065
-2.6
-12.4
CBS domain-containing protein
compare
MMJJ
_RS07410
-2.5
-3.9
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS03830
-2.5
-10.6
CBS domain-containing protein
compare
MMJJ
_RS06040
-2.5
-4.1
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS06840
-2.5
-4.4
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS06220
-2.5
-6.5
polyamine aminopropyltransferase
compare
MMJJ
_RS00050
-2.4
-12.2
AAA family ATPase
compare
MMJJ
_RS00645
-2.4
-10.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS04670
-2.4
-4.6
DUF2117 domain-containing protein
compare
MMJJ
_RS07785
-2.4
-3.0
fumarate reductase subunit A
compare
MMJJ
_RS07980
-2.4
-10.4
biotin synthase BioB
compare
MMJJ
_RS03865
-2.4
-2.3
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS06855
-2.4
-2.2
DUF2104 domain-containing protein
compare
MMJJ
_RS04050
-2.4
-2.5
dihydroneopterin aldolase family protein
compare
MMJJ
_RS06250
-2.4
-3.0
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS06510
-2.3
-3.6
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS07245
-2.3
-5.4
amidohydrolase family protein
compare
MMJJ
_RS07635
-2.3
-11.6
response regulator transcription factor
compare
MMJJ
_RS05360
-2.3
-5.8
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS04615
-2.3
-6.1
methanogenesis marker 3 protein
compare
MMJJ
_RS06375
-2.3
-4.8
UbiX family flavin prenyltransferase
compare
MMJJ
_RS00475
-2.3
-3.1
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS03875
-2.3
-4.4
CBS domain-containing protein
compare
MMJJ
_RS04475
-2.3
-4.6
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS04520
-2.3
-4.9
coenzyme F430 synthase
compare
MMJJ
_RS05190
-2.3
-10.0
gamma carbonic anhydrase family protein
compare
MMJJ
_RS05590
-2.3
-2.1
homoserine dehydrogenase
compare
MMJJ
_RS05620
-2.3
-5.0
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS07950
-2.3
-2.9
4Fe-4S binding protein
compare
MMJJ
_RS00195
-2.2
-3.5
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS07995
-2.2
-6.6
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS06835
-2.2
-9.9
4Fe-4S binding protein
compare
MMJJ
_RS01865
-2.2
-5.1
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS04675
-2.2
-5.5
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS02055
-2.2
-11.4
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS05595
-2.2
-2.9
hypothetical protein
compare
MMJJ
_RS06730
-2.2
-6.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03630
-2.2
-10.5
AMP phosphorylase
compare
MMJJ
_RS03800
-2.2
-10.5
aldolase
compare
MMJJ
_RS05930
-2.2
-2.5
cell division protein SepF
compare
MMJJ
_RS06180
-2.2
-3.6
tryptophan--tRNA ligase
compare
MMJJ
_RS07155
-2.2
-8.4
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS07190
-2.2
-4.8
RtcB family protein
compare
MMJJ
_RS06225
-2.2
-2.5
adenosylmethionine decarboxylase
compare
MMJJ
_RS03055
-2.2
-2.5
hypothetical protein
compare
MMJJ
_RS05810
-2.1
-7.0
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS05935
-2.1
-3.0
Era-like GTP-binding protein
compare
MMJJ
_RS00070
-2.1
-4.6
CooT family nickel-binding protein
compare
MMJJ
_RS00045
-2.1
-12.5
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS06875
-2.1
-3.2
hypothetical protein
compare
MMJJ
_RS04655
-2.1
-6.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS08840
-2.1
-4.2
calcium/sodium antiporter
compare
MMJJ
_RS03095
-2.1
-2.6
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS04010
-2.1
-7.9
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS06865
-2.1
-2.6
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS00035
-2.1
-14.2
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS04485
-2.1
-6.6
riboflavin synthase
compare
MMJJ
_RS06390
-2.1
-2.0
NADPH-dependent F420 reductase
compare
MMJJ
_RS00055
-2.1
-9.9
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS07640
-2.1
-16.6
cache domain-containing protein
compare
MMJJ
_RS01880
-2.1
-2.5
RlmE family RNA methyltransferase
compare
MMJJ
_RS05375
-2.0
-13.4
radical SAM protein
compare
MMJJ
_RS05070
-2.0
-1.8
DNA primase catalytic subunit PriS
compare
MMJJ
_RS07650
-2.0
-13.4
formate/nitrite transporter family protein
compare
MMJJ
_RS03115
-2.0
-5.5
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS00040
-2.0
-7.5
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS03160
-2.0
-13.2
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS06050
-2.0
-9.8
molybdopterin molybdotransferase MoeA
compare
MMJJ
_RS06240
-2.0
-2.8
dihydropteroate synthase-like protein
compare
MMJJ
_RS00515
-2.0
-11.1
cobalt transporter CbiM
compare
MMJJ
_RS02935
-2.0
-3.3
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS05995
-2.0
-2.1
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS07720
-2.0
-2.4
UPF0058 family protein
compare
MMJJ
_RS07430
-2.0
-3.4
ribonuclease VapC
compare
MMJJ
_RS08795
-2.0
-3.0
phosphoglucosamine mutase
compare
MMJJ
_RS06215
-2.0
-5.0
agmatinase
compare
MMJJ
_RS00065
-1.9
-10.1
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS07415
-1.9
-2.7
polyprenyl diphosphate synthase
compare
MMJJ
_RS05295
-1.9
-8.9
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS07705
-1.9
-3.8
GTP-binding protein EngB
compare
MMJJ
_RS00080
-1.9
-11.9
DUF166 domain-containing protein
compare
MMJJ
_RS03060
-1.9
-2.0
methanogenesis marker 7 protein
compare
MMJJ
_RS06265
-1.9
-11.3
8-amino-7-oxononanoate synthase
compare
MMJJ
_RS08155
-1.9
-2.6
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS00530
-1.9
-10.6
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS08660
-1.9
-3.9
acetylornithine transaminase
compare
MMJJ
_RS03965
-1.9
-1.8
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS07725
-1.9
-6.9
DNA primase DnaG
compare
MMJJ
_RS01345
-1.9
-3.9
(5-formylfuran-3-yl)methyl phosphate synthase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments