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Experiment set3IT035 for
Methanococcus maripaludis JJ
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formate McAA biotin dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.2
-22.0
hypothetical protein
compare
MMJJ
_RS00570
-5.8
-3.1
ribonuclease P
compare
MMJJ
_RS03270
-5.7
-3.5
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS06695
-5.3
-3.7
amidohydrolase
compare
MMJJ
_RS04200
-5.0
-8.3
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS07360
-5.0
-2.7
TIGR00269 family protein
compare
MMJJ
_RS06910
-4.7
-3.2
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS05450
-4.6
-18.9
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS02045
-4.6
-4.4
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS05950
-4.6
-3.1
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS00275
-4.5
-3.9
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS00450
-4.5
-2.8
DUF126 domain-containing protein
compare
MMJJ
_RS05930
-4.5
-3.1
cell division protein SepF
compare
MMJJ
_RS01870
-4.4
-3.0
methanogenesis marker 15 protein
compare
MMJJ
_RS05575
-4.4
-6.0
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS08250
-4.4
-8.4
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS03615
-4.4
-4.7
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS06625
-4.3
-3.3
pyruvate synthase subunit PorB
compare
MMJJ
_RS06240
-4.2
-5.0
dihydropteroate synthase-like protein
compare
MMJJ
_RS05650
-4.2
-4.0
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS07720
-4.1
-3.4
UPF0058 family protein
compare
MMJJ
_RS06510
-4.1
-4.8
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS06110
-4.0
-2.8
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS04790
-4.0
-6.1
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS06860
-4.0
-4.9
hypothetical protein
compare
MMJJ
_RS07350
-4.0
-3.9
4Fe-4S binding protein
compare
MMJJ
_RS05995
-3.9
-3.1
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03820
-3.9
-5.3
hydrogenase formation protein HypD
compare
MMJJ
_RS07665
-3.9
-24.2
formate dehydrogenase subunit alpha
compare
MMJJ
_RS04730
-3.9
-3.7
tyrosine decarboxylase MfnA
compare
MMJJ
_RS04155
-3.8
-8.8
hypothetical protein
compare
MMJJ
_RS06180
-3.8
-3.7
tryptophan--tRNA ligase
compare
MMJJ
_RS05610
-3.8
-5.7
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS06750
-3.8
-3.3
homoaconitase large subunit
compare
MMJJ
_RS04970
-3.7
-3.1
DUF655 domain-containing protein
compare
MMJJ
_RS06485
-3.7
-4.3
phosphoglycerate kinase
compare
MMJJ
_RS05535
-3.7
-16.2
hypothetical protein
compare
MMJJ
_RS06490
-3.7
-4.3
methanogenesis marker 2 protein
compare
MMJJ
_RS06840
-3.7
-5.0
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS07950
-3.7
-4.2
4Fe-4S binding protein
compare
MMJJ
_RS08020
-3.7
-10.7
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS00270
-3.6
-4.9
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS04800
-3.6
-8.0
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS07000
-3.6
-3.0
TrkH family potassium uptake protein
compare
MMJJ
_RS04975
-3.6
-3.0
glycosyltransferase family 4 protein
compare
MMJJ
_RS04475
-3.6
-5.8
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS08320
-3.6
-3.0
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS03840
-3.6
-5.8
DHH family phosphoesterase
compare
MMJJ
_RS07670
-3.5
-17.9
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS01750
-3.5
-3.4
ferrous iron transport protein A
compare
MMJJ
_RS07705
-3.5
-4.7
GTP-binding protein EngB
compare
MMJJ
_RS05935
-3.5
-3.8
Era-like GTP-binding protein
compare
MMJJ
_RS02090
-3.5
-8.0
tyramine--L-glutamate ligase
compare
MMJJ
_RS06725
-3.5
-13.7
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS07380
-3.5
-9.4
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS06040
-3.4
-6.1
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS02920
-3.3
-2.5
30S ribosomal protein S27ae
compare
MMJJ
_RS05330
-3.3
-3.2
DNA polymerase II large subunit
compare
MMJJ
_RS04485
-3.3
-9.9
riboflavin synthase
compare
MMJJ
_RS06915
-3.3
-15.2
helix-turn-helix domain-containing protein
compare
MMJJ
_RS07655
-3.3
-15.9
hypothetical protein
compare
MMJJ
_RS01935
-3.3
-6.6
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS03125
-3.3
-5.7
GMC oxidoreductase
compare
MMJJ
_RS01600
-3.3
-4.2
radical SAM protein
compare
MMJJ
_RS06375
-3.3
-5.0
UbiX family flavin prenyltransferase
compare
MMJJ
_RS05260
-3.3
-7.2
ATP-grasp domain-containing protein
compare
MMJJ
_RS06785
-3.3
-11.0
RNA ligase partner protein
compare
MMJJ
_RS04685
-3.2
-12.6
carbamoyltransferase HypF
compare
MMJJ
_RS08660
-3.2
-4.5
acetylornithine transaminase
compare
MMJJ
_RS09375
-3.2
-2.8
hypothetical protein
compare
MMJJ
_RS06255
-3.2
-8.7
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS06905
-3.1
-3.4
hypothetical protein
compare
MMJJ
_RS03055
-3.1
-3.8
hypothetical protein
compare
MMJJ
_RS08625
-3.1
-8.7
magnesium/cobalt transporter CorA
compare
MMJJ
_RS08840
-3.1
-6.1
calcium/sodium antiporter
compare
MMJJ
_RS05070
-3.1
-3.6
DNA primase catalytic subunit PriS
compare
MMJJ
_RS08000
-3.0
-9.9
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS00475
-3.0
-3.6
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS08005
-3.0
-18.2
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS07945
-3.0
-4.2
4Fe-4S binding protein
compare
MMJJ
_RS06155
-3.0
-6.8
phosphatidylglycerophosphatase A
compare
MMJJ
_RS06875
-3.0
-4.6
hypothetical protein
compare
MMJJ
_RS03875
-3.0
-4.6
CBS domain-containing protein
compare
MMJJ
_RS01565
-3.0
-9.0
TIGR00267 family protein
compare
MMJJ
_RS08335
-3.0
-3.1
ABC transporter ATP-binding protein
compare
MMJJ
_RS06855
-2.9
-2.9
DUF2104 domain-containing protein
compare
MMJJ
_RS00560
-2.9
-5.3
homoisocitrate dehydrogenase
compare
MMJJ
_RS08080
-2.9
-11.4
TIGR00300 family protein
compare
MMJJ
_RS00195
-2.9
-5.0
precorrin-3B C(17)-methyltransferase
compare
MMJJ
_RS00580
-2.9
-2.4
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS06390
-2.8
-2.8
NADPH-dependent F420 reductase
compare
MMJJ
_RS03670
-2.8
-5.3
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS02275
-2.8
-6.2
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03760
-2.8
-3.8
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS05810
-2.8
-8.7
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS07410
-2.8
-4.9
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS08330
-2.8
-4.6
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS03965
-2.8
-2.7
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS01755
-2.8
-3.2
ferrous iron transport protein B
compare
MMJJ
_RS03115
-2.8
-7.5
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS08055
-2.8
-7.9
methanogenesis marker 14 protein
compare
MMJJ
_RS00600
-2.8
-4.0
hydroxymethylbilane synthase
compare
MMJJ
_RS04995
-2.7
-6.2
Tfx family DNA-binding protein
compare
MMJJ
_RS03815
-2.7
-3.0
nascent polypeptide-associated complex protein
compare
MMJJ
_RS01345
-2.7
-5.2
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS01360
-2.7
-3.4
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS03005
-2.7
-5.0
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS04050
-2.7
-2.2
dihydroneopterin aldolase family protein
compare
MMJJ
_RS05225
-2.7
-2.3
Gar1/Naf1 family protein
compare
MMJJ
_RS03110
-2.7
-4.7
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS01690
-2.7
-3.6
methanogenesis marker 12 protein
compare
MMJJ
_RS00355
-2.7
-3.1
ribonuclease P protein component 4
compare
MMJJ
_RS04520
-2.6
-6.0
coenzyme F430 synthase
compare
MMJJ
_RS07980
-2.6
-11.7
biotin synthase BioB
compare
MMJJ
_RS06270
-2.6
-10.5
dethiobiotin synthase
compare
MMJJ
_RS03660
-2.6
-5.3
DUF447 family protein
compare
MMJJ
_RS07660
-2.6
-13.2
carbonic anhydrase
compare
MMJJ
_RS03580
-2.6
-4.1
TIGR00303 family protein
compare
MMJJ
_RS06175
-2.6
-3.8
DUF1743 domain-containing protein
compare
MMJJ
_RS03785
-2.6
-2.9
hypothetical protein
compare
MMJJ
_RS07995
-2.6
-9.6
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS08155
-2.5
-5.7
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS05065
-2.5
-6.0
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS05655
-2.5
-6.6
HisA/HisF family protein
compare
MMJJ
_RS00645
-2.5
-12.8
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS03800
-2.5
-11.6
aldolase
compare
MMJJ
_RS04675
-2.5
-7.9
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS06835
-2.5
-12.0
4Fe-4S binding protein
compare
MMJJ
_RS03150
-2.5
-6.1
2-phospho-L-lactate transferase
compare
MMJJ
_RS03295
-2.5
-15.7
PHP domain-containing protein
compare
MMJJ
_RS08095
-2.5
-4.6
cobyric acid synthase CobQ
compare
MMJJ
_RS05620
-2.5
-5.6
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS04615
-2.5
-3.6
methanogenesis marker 3 protein
compare
MMJJ
_RS03830
-2.5
-10.4
CBS domain-containing protein
compare
MMJJ
_RS01475
-2.5
-2.9
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS00520
-2.5
-7.2
PDGLE domain-containing protein
compare
MMJJ
_RS04875
-2.4
-2.2
tRNA-Lys
compare
MMJJ
_RS05490
-2.4
-3.7
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS06730
-2.4
-6.6
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS03060
-2.4
-4.2
methanogenesis marker 7 protein
compare
MMJJ
_RS06220
-2.4
-6.0
polyamine aminopropyltransferase
compare
MMJJ
_RS09190
-2.4
-2.6
tryptophan synthase subunit beta
compare
MMJJ
_RS00075
-2.4
-11.3
AAA family ATPase
compare
MMJJ
_RS08535
-2.4
-4.7
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS00515
-2.3
-12.4
cobalt transporter CbiM
compare
MMJJ
_RS01415
-2.3
-3.3
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS03895
-2.3
-2.4
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS00045
-2.3
-12.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS06705
-2.3
-5.6
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS03620
-2.3
-4.5
DUF2097 domain-containing protein
compare
MMJJ
_RS04595
-2.3
-5.8
hypothetical protein
compare
MMJJ
_RS04650
-2.3
-6.5
nitrogenase iron protein
compare
MMJJ
_RS07275
-2.3
-3.5
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS07245
-2.3
-5.4
amidohydrolase family protein
compare
MMJJ
_RS00370
-2.3
-2.5
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS06250
-2.3
-3.6
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS03190
-2.3
-3.2
phosphopyruvate hydratase
compare
MMJJ
_RS00210
-2.3
-2.7
DUF530 family protein
compare
MMJJ
_RS07840
-2.3
-2.5
Glu-tRNA(Gln) amidotransferase subunit GatD
compare
MMJJ
_RS02935
-2.3
-3.8
DNA-directed RNA polymerase subunit E''
compare
MMJJ
_RS05360
-2.3
-7.2
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS03065
-2.3
-11.6
CBS domain-containing protein
compare
MMJJ
_RS00040
-2.2
-11.1
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS07345
-2.2
-6.1
homocysteine biosynthesis protein
compare
MMJJ
_RS05295
-2.2
-10.9
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS07370
-2.2
-3.7
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS00060
-2.2
-13.7
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS03630
-2.2
-10.8
AMP phosphorylase
compare
MMJJ
_RS03200
-2.2
-2.8
uroporphyrinogen-III synthase
compare
MMJJ
_RS08340
-2.2
-4.2
archaeoflavoprotein AfpA
compare
MMJJ
_RS00065
-2.2
-11.1
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS00035
-2.2
-16.3
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS03865
-2.2
-2.4
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS00530
-2.2
-12.0
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS08065
-2.2
-3.3
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS07155
-2.2
-8.6
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS05445
-2.2
-2.5
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS01865
-2.2
-5.0
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS05190
-2.2
-6.9
gamma carbonic anhydrase family protein
compare
MMJJ
_RS01355
-2.2
-3.2
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS06930
-2.2
-3.8
type II methionyl aminopeptidase
compare
MMJJ
_RS07190
-2.2
-5.2
RtcB family protein
compare
MMJJ
_RS01880
-2.1
-3.1
RlmE family RNA methyltransferase
compare
MMJJ
_RS06260
-2.1
-8.0
6-carboxyhexanoate--CoA ligase
compare
MMJJ
_RS00050
-2.1
-9.3
AAA family ATPase
compare
MMJJ
_RS06225
-2.1
-2.7
adenosylmethionine decarboxylase
compare
MMJJ
_RS02055
-2.1
-13.6
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS08855
-2.1
-5.0
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS08620
-2.1
-3.4
DUF373 family protein
compare
MMJJ
_RS06185
-2.1
-5.2
cobalamin biosynthesis protein
compare
MMJJ
_RS00080
-2.1
-12.8
DUF166 domain-containing protein
compare
MMJJ
_RS04670
-2.0
-4.6
DUF2117 domain-containing protein
compare
MMJJ
_RS00055
-2.0
-10.9
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS07725
-2.0
-6.2
DNA primase DnaG
compare
MMJJ
_RS00070
-2.0
-4.2
CooT family nickel-binding protein
compare
MMJJ
_RS05375
-2.0
-13.9
radical SAM protein
compare
MMJJ
_RS05590
-2.0
-2.2
homoserine dehydrogenase
compare
MMJJ
_RS09175
-2.0
-1.8
anthranilate synthase component I
compare
MMJJ
_RS08850
-2.0
-2.6
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS06215
-2.0
-3.2
agmatinase
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments