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Experiment set3IT034 for
Methanococcus maripaludis S2
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H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS01175
-8.8
-3.7
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS07645
-8.2
-4.5
aldehyde dehydrogenase family protein
compare
MMP
_RS00895
-7.3
-3.0
hypothetical protein
compare
MMP
_RS07845
-7.3
-2.9
LL-diaminopimelate aminotransferase
compare
MMP
_RS06120
-6.7
-2.3
UPF0147 family protein
compare
MMP
_RS08440
-6.5
-3.5
cell division protein SepF
compare
MMP
_RS03400
-6.5
-2.5
archease
compare
MMP
_RS06355
-6.5
-2.6
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS08210
-6.4
-2.2
phosphatidylglycerophosphatase A
compare
MMP
_RS08820
-6.2
-5.7
hypothetical protein
compare
MMP
_RS06370
-6.2
-4.3
biotin synthase BioB
compare
MMP
_RS03435
-6.0
-2.1
ketol-acid reductoisomerase
compare
MMP
_RS01725
-5.9
-4.1
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS06400
-5.8
-1.7
4Fe-4S binding protein
compare
MMP
_RS02195
-5.8
-4.1
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS06730
-5.7
-2.0
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS03035
-5.7
-3.8
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS08105
-5.6
-7.4
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS01955
-5.6
-2.1
hypothetical protein
compare
MMP
_RS04500
-5.6
-18.5
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS06900
-5.5
-3.1
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS07750
-5.5
-5.2
DUF357 domain-containing protein
compare
MMP
_RS08650
-5.5
-2.8
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS00305
-5.4
-2.1
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS06285
-5.4
-2.4
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS04720
-5.3
-3.0
DedA family protein
compare
MMP
_RS01500
-5.3
-2.7
CBS domain-containing protein
compare
MMP
_RS06925
-5.2
-2.7
ribonuclease VapC4
compare
MMP
_RS08460
-5.2
-2.2
proteasome-activating nucleotidase
compare
MMP
_RS01830
-5.1
-1.2
tRNA-Val
compare
MMP
_RS03315
-5.1
-1.5
ferrous iron transport protein A
compare
MMP
_RS00300
-5.1
-0.9
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS09020
-5.0
-1.9
hypothetical protein
compare
MMP
_RS05265
-5.0
-2.1
2-isopropylmalate synthase
compare
MMP
_RS06895
-4.9
-2.0
selenocysteine-specific translation elongation factor
compare
MMP
_RS08435
-4.9
-2.8
Era-like GTP-binding protein
compare
MMP
_RS03015
-4.9
-11.3
GTP 3' 8-cyclase MoaA
compare
MMP
_RS01940
-4.9
-4.4
MoxR family ATPase
compare
MMP
_RS01910
-4.9
-10.4
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS02135
-4.8
-5.9
DUF5612 domain-containing protein
compare
MMP
_RS06270
-4.8
-6.2
TIGR00300 family protein
compare
MMP
_RS06475
-4.8
-5.7
FAD-dependent oxidoreductase
compare
MMP
_RS01225
-4.8
-6.2
DUF5379 domain-containing protein
compare
MMP
_RS07730
-4.8
-1.8
pyruvate synthase subunit beta
compare
MMP
_RS00520
-4.8
-2.0
RNA polymerase Rpb4 family protein
compare
MMP
_RS02355
-4.8
-3.1
30S ribosomal protein S27ae
compare
MMP
_RS07755
-4.8
-1.2
DUF555 domain-containing protein
compare
MMP
_RS01220
-4.8
-8.6
hypothetical protein
compare
MMP
_RS01325
-4.7
-2.4
dihydroneopterin aldolase family protein
compare
MMP
_RS07635
-4.7
-8.4
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS04775
-4.7
-3.3
adenosylhomocysteinase
compare
MMP
_RS05515
-4.7
-7.2
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS02010
-4.7
-10.6
PHP domain-containing protein
compare
MMP
_RS03700
-4.7
-9.8
sodium:proton antiporter
compare
MMP
_RS03025
-4.6
-5.7
molybdenum cofactor guanylyltransferase
compare
MMP
_RS01385
-4.6
-0.8
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS07195
-4.5
-9.1
M20 family metallo-hydrolase
compare
MMP
_RS08100
-4.5
-6.5
8-amino-7-oxononanoate synthase
compare
MMP
_RS05920
-4.5
-0.8
50S ribosomal protein L37e
compare
MMP
_RS08095
-4.5
-8.0
dethiobiotin synthase
compare
MMP
_RS06670
-4.5
-6.4
glucose-6-phosphate isomerase
compare
MMP
_RS00685
-4.5
-5.3
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS08720
-4.5
-1.5
4Fe-4S binding protein
compare
MMP
_RS03475
-4.5
-0.8
hypothetical protein
compare
MMP
_RS01020
-4.5
-1.1
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS07005
-4.4
-0.8
4Fe-4S binding protein
compare
MMP
_RS01005
-4.4
-1.5
riboflavin synthase
compare
MMP
_RS03640
-4.4
-4.2
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS08635
-4.4
-1.8
UbiA family prenyltransferase
compare
MMP
_RS08300
-4.4
-1.3
metal-sulfur cluster assembly factor
compare
MMP
_RS06020
-4.4
-5.3
archaeoflavoprotein AfpA
compare
MMP
_RS07600
-4.4
-2.7
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS02240
-4.3
-3.8
methanogenesis marker 7 protein
compare
MMP
_RS00515
-4.3
-1.1
DUF655 domain-containing protein
compare
MMP
_RS05930
-4.3
-2.9
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS04685
-4.3
-3.5
DUF126 domain-containing protein
compare
MMP
_RS06350
-4.3
-6.5
HesA/MoeB/ThiF family protein
compare
MMP
_RS01905
-4.2
-12.1
glycosyltransferase
compare
MMP
_RS05845
-4.2
-2.0
tRNA-intron lyase
compare
MMP
_RS02875
-4.2
-9.2
chorismate pyruvate-lyase family protein
compare
MMP
_RS07435
-4.2
-2.3
GMP synthase subunit A
compare
MMP
_RS01915
-4.1
-13.4
DUF354 domain-containing protein
compare
MMP
_RS03600
-4.1
-2.5
triose-phosphate isomerase
compare
MMP
_RS07200
-4.1
-6.9
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS06625
-4.1
-2.4
DNA primase
compare
MMP
_RS01880
-4.1
-5.8
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS07605
-4.1
-3.0
diadenylate cyclase
compare
MMP
_RS08715
-4.1
-2.0
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS00040
-4.1
-5.0
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS07390
-4.0
-3.4
cell division protein FtsZ
compare
MMP
_RS08790
-4.0
-2.7
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS05815
-4.0
-4.1
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS06315
-4.0
-1.0
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS06885
-4.0
-3.1
50S ribosome-binding GTPase
compare
MMP
_RS01920
-3.9
-10.7
glycosyltransferase family 2 protein
compare
MMP
_RS01925
-3.9
-8.0
DUF1616 domain-containing protein
compare
MMP
_RS01700
-3.9
-1.0
dihydroxy-acid dehydratase
compare
MMP
_RS02190
-3.9
-2.9
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS01335
-3.9
-2.5
prefoldin subunit beta
compare
MMP
_RS06215
-3.8
-2.7
30S ribosomal protein S6e
compare
MMP
_RS00695
-3.8
-0.9
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS03960
-3.8
-1.1
hypothetical protein
compare
MMP
_RS01800
-3.8
-4.3
TIGR00303 family protein
compare
MMP
_RS06295
-3.8
-9.1
methanogenesis marker 14 protein
compare
MMP
_RS07380
-3.7
-2.5
transcription elongation factor Spt5
compare
MMP
_RS00110
-3.7
-2.8
hypothetical protein
compare
MMP
_RS01885
-3.7
-8.0
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS04780
-3.7
-2.8
ribonuclease P
compare
MMP
_RS08745
-3.6
-7.6
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS02280
-3.5
-0.9
DUF211 domain-containing protein
compare
MMP
_RS01610
-3.5
-3.5
hypothetical protein
compare
MMP
_RS02345
-3.5
-4.3
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS06630
-3.5
-1.2
UPF0058 family protein
compare
MMP
_RS06980
-3.5
-8.5
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS03140
-3.5
-15.9
hypothetical protein
compare
MMP
_RS01755
-3.5
-1.4
DUF2097 domain-containing protein
compare
MMP
_RS04890
-3.5
-0.8
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS00115
-3.4
-12.2
radical SAM protein
compare
MMP
_RS03445
-3.4
-1.2
methanogenesis marker 17 protein
compare
MMP
_RS04710
-3.3
-1.8
hypothetical protein
compare
MMP
_RS05640
-3.3
-6.6
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS02145
-3.3
-4.5
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS01895
-3.3
-8.6
flippase
compare
MMP
_RS00050
-3.2
-7.9
AarF/UbiB family protein
compare
MMP
_RS01900
-3.2
-17.4
hypothetical protein
compare
MMP
_RS06340
-3.2
-6.4
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS02245
-3.2
-2.5
hypothetical protein
compare
MMP
_RS01875
-3.2
-7.9
N-acetyltransferase
compare
MMP
_RS06230
-3.1
-2.7
helix-turn-helix domain-containing protein
compare
MMP
_RS07555
-3.1
-0.7
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS03580
-3.1
-2.8
signal recognition particle-docking protein FtsY
compare
MMP
_RS03155
-3.1
-7.6
precorrin-6A reductase
compare
MMP
_RS07580
-3.0
-3.4
DUF356 domain-containing protein
compare
MMP
_RS00325
-3.0
-1.9
RNA-binding protein
compare
MMP
_RS03145
-3.0
-7.1
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS02800
-3.0
-5.4
nucleotidyltransferase domain-containing protein
compare
MMP
_RS02900
-3.0
-0.7
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS00810
-2.9
-9.7
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS05345
-2.9
-7.9
hypothetical protein
compare
MMP
_RS01890
-2.8
-4.6
nucleotide sugar dehydrogenase
compare
MMP
_RS07545
-2.8
-1.0
HTH domain-containing protein
compare
MMP
_RS03095
-2.8
-8.9
diphthine synthase
compare
MMP
_RS06865
-2.8
-1.7
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS05440
-2.8
-8.0
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS01970
-2.8
-6.0
TIGR04279 domain-containing protein
compare
MMP
_RS01945
-2.8
-5.0
DUF4350 domain-containing protein
compare
MMP
_RS01365
-2.7
-3.0
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS04850
-2.7
-16.1
UPF0254 family protein
compare
MMP
_RS01930
-2.7
-11.2
hypothetical protein
compare
MMP
_RS05250
-2.7
-1.9
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS00735
-2.7
-3.5
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS05525
-2.6
-7.3
calcium/sodium antiporter
compare
MMP
_RS06940
-2.6
-4.0
polyprenyl diphosphate synthase
compare
MMP
_RS04585
-2.6
-9.5
AIR synthase related protein
compare
MMP
_RS07695
-2.6
-9.2
DUF3236 domain-containing protein
compare
MMP
_RS07425
-2.6
-5.6
GTP-binding protein
compare
MMP
_RS07075
-2.6
-3.6
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS01935
-2.5
-6.3
DUF58 domain-containing protein
compare
MMP
_RS01795
-2.5
-1.8
methanogenesis marker 6 protein
compare
MMP
_RS00450
-2.4
-2.3
4Fe-4S binding protein
compare
MMP
_RS06105
-2.4
-9.0
hydrogenase maturation peptidase HycI
compare
MMP
_RS00315
-2.4
-8.2
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS08785
-2.4
-1.3
RNA-protein complex protein Nop10
compare
MMP
_RS07355
-2.4
-0.9
transcription factor S
compare
MMP
_RS06130
-2.4
-4.4
peptidylprolyl isomerase
compare
MMP
_RS06310
-2.4
-2.6
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS07955
-2.3
-5.8
FumA C-terminus/TtdB family hydratase beta subunit
compare
MMP
_RS04955
-2.3
-5.9
DNA topoisomerase I
compare
MMP
_RS01665
-2.3
-3.1
DUF2111 domain-containing protein
compare
MMP
_RS05555
-2.3
-1.3
DUF4040 domain-containing protein
compare
MMP
_RS06725
-2.3
-11.8
hypothetical protein
compare
MMP
_RS02340
-2.3
-2.1
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS03205
-2.3
-1.5
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS00725
-2.2
-6.5
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS01840
-2.2
-7.0
TIGR00289 family protein
compare
MMP
_RS06395
-2.2
-3.4
ThiF family adenylyltransferase
compare
MMP
_RS07735
-2.2
-0.8
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01380
-2.2
-2.6
PHP domain-containing protein
compare
MMP
_RS00320
-2.2
-1.8
class I SAM-dependent methyltransferase
compare
MMP
_RS08445
-2.2
-4.2
DUF2099 family protein
compare
MMP
_RS01960
-2.2
-0.5
hypothetical protein
compare
MMP
_RS00985
-2.2
-4.5
CDC48 family AAA ATPase
compare
MMP
_RS07090
-2.2
-8.1
tRNA (adenine-N1)-methyltransferase
compare
MMP
_RS01975
-2.1
-9.0
hypothetical protein
compare
MMP
_RS01950
-2.1
-6.4
hypothetical protein
compare
MMP
_RS05425
-2.1
-5.4
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS07525
-2.1
-9.4
4Fe-4S binding protein
compare
MMP
_RS00900
-2.1
-2.3
50S ribosomal protein L39e
compare
MMP
_RS01475
-2.0
-9.3
phosphosulfolactate synthase
compare
MMP
_RS08330
-2.0
-2.5
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS01030
-2.0
-2.4
MTAP family purine nucleoside phosphorylase
compare
MMP
_RS07875
-1.9
-4.7
hypothetical protein
compare
MMP
_RS05445
-1.9
-7.2
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS07700
-1.9
-10.6
DUF1188 domain-containing protein
compare
MMP
_RS07420
-1.9
-4.0
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS00720
-1.9
-5.0
metal-dependent hydrolase
compare
MMP
_RS00130
-1.9
-1.1
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS00730
-1.8
-3.3
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS07540
-1.8
-3.5
CBS domain-containing protein
compare
MMP
_RS06110
-1.8
-2.3
ATP-dependent protease LonB
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in rich t2 experiments