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Experiment set3IT034 for
Methanococcus maripaludis JJ
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formate McAA biotin dropout
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS00235
-6.2
-23.2
hypothetical protein
compare
MMJJ
_RS01935
-5.4
-3.7
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS06625
-5.2
-3.2
pyruvate synthase subunit PorB
compare
MMJJ
_RS05995
-5.0
-3.4
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS08330
-5.0
-3.4
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS05450
-4.9
-18.4
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS06860
-4.8
-6.4
hypothetical protein
compare
MMJJ
_RS04485
-4.8
-11.5
riboflavin synthase
compare
MMJJ
_RS06695
-4.5
-4.4
amidohydrolase
compare
MMJJ
_RS00450
-4.5
-2.8
DUF126 domain-containing protein
compare
MMJJ
_RS05930
-4.4
-3.0
cell division protein SepF
compare
MMJJ
_RS01415
-4.3
-4.2
beta-CASP ribonuclease aCPSF1
compare
MMJJ
_RS01750
-4.3
-4.1
ferrous iron transport protein A
compare
MMJJ
_RS03875
-4.3
-5.8
CBS domain-containing protein
compare
MMJJ
_RS04200
-4.2
-7.8
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS00580
-4.1
-2.9
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS05575
-4.0
-6.0
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS05445
-4.0
-3.2
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS06875
-4.0
-3.6
hypothetical protein
compare
MMJJ
_RS03840
-4.0
-4.7
DHH family phosphoesterase
compare
MMJJ
_RS06490
-4.0
-3.9
methanogenesis marker 2 protein
compare
MMJJ
_RS06840
-4.0
-3.9
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS06240
-4.0
-4.3
dihydropteroate synthase-like protein
compare
MMJJ
_RS00560
-3.9
-5.3
homoisocitrate dehydrogenase
compare
MMJJ
_RS05650
-3.9
-4.6
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS02920
-3.9
-3.7
30S ribosomal protein S27ae
compare
MMJJ
_RS03110
-3.9
-5.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS03865
-3.9
-1.9
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS08320
-3.8
-3.6
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS00125
-3.8
-2.6
KEOPS complex subunit Cgi121
compare
MMJJ
_RS03580
-3.8
-5.2
TIGR00303 family protein
compare
MMJJ
_RS01755
-3.8
-2.6
ferrous iron transport protein B
compare
MMJJ
_RS05950
-3.8
-4.5
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS00270
-3.8
-5.1
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS01475
-3.7
-3.2
signal recognition particle-docking protein FtsY
compare
MMJJ
_RS08020
-3.7
-10.8
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS06510
-3.7
-3.3
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS05610
-3.6
-5.9
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS07950
-3.6
-4.1
4Fe-4S binding protein
compare
MMJJ
_RS03785
-3.6
-3.4
hypothetical protein
compare
MMJJ
_RS02090
-3.6
-7.6
tyramine--L-glutamate ligase
compare
MMJJ
_RS07665
-3.5
-20.5
formate dehydrogenase subunit alpha
compare
MMJJ
_RS06040
-3.5
-5.2
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS00570
-3.4
-2.9
ribonuclease P
compare
MMJJ
_RS06725
-3.4
-12.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS05070
-3.4
-3.2
DNA primase catalytic subunit PriS
compare
MMJJ
_RS05620
-3.4
-5.6
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS03760
-3.4
-5.5
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS07380
-3.4
-9.5
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMJJ
_RS08250
-3.4
-8.6
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS03615
-3.4
-4.1
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS07670
-3.3
-17.4
Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
compare
MMJJ
_RS08055
-3.3
-9.8
methanogenesis marker 14 protein
compare
MMJJ
_RS09130
-3.3
-2.5
NFYB/HAP3 family transcription factor subunit
compare
MMJJ
_RS05535
-3.3
-15.3
hypothetical protein
compare
MMJJ
_RS05415
-3.3
-2.2
hypothetical protein
compare
MMJJ
_RS04155
-3.3
-7.9
hypothetical protein
compare
MMJJ
_RS01600
-3.3
-4.2
radical SAM protein
compare
MMJJ
_RS04685
-3.3
-11.7
carbamoyltransferase HypF
compare
MMJJ
_RS03005
-3.3
-4.9
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS03670
-3.3
-5.5
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS07785
-3.2
-4.0
fumarate reductase subunit A
compare
MMJJ
_RS01690
-3.2
-4.4
methanogenesis marker 12 protein
compare
MMJJ
_RS03620
-3.2
-8.2
DUF2097 domain-containing protein
compare
MMJJ
_RS03150
-3.2
-8.7
2-phospho-L-lactate transferase
compare
MMJJ
_RS04970
-3.2
-2.9
DUF655 domain-containing protein
compare
MMJJ
_RS04995
-3.2
-7.9
Tfx family DNA-binding protein
compare
MMJJ
_RS06915
-3.2
-14.7
helix-turn-helix domain-containing protein
compare
MMJJ
_RS08080
-3.2
-9.7
TIGR00300 family protein
compare
MMJJ
_RS07655
-3.2
-15.9
hypothetical protein
compare
MMJJ
_RS08625
-3.2
-7.5
magnesium/cobalt transporter CorA
compare
MMJJ
_RS09375
-3.1
-2.5
hypothetical protein
compare
MMJJ
_RS03060
-3.1
-4.2
methanogenesis marker 7 protein
compare
MMJJ
_RS04800
-3.1
-8.5
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS06910
-3.1
-3.1
energy-converting NiFe hydrogenase A subunit EhaA
compare
MMJJ
_RS03815
-3.0
-3.2
nascent polypeptide-associated complex protein
compare
MMJJ
_RS03095
-3.0
-3.6
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS03270
-3.0
-3.6
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS06255
-3.0
-8.0
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS07705
-3.0
-4.8
GTP-binding protein EngB
compare
MMJJ
_RS01865
-2.9
-7.2
peptidyl-tRNA hydrolase Pth2
compare
MMJJ
_RS08335
-2.9
-3.1
ABC transporter ATP-binding protein
compare
MMJJ
_RS02275
-2.9
-4.8
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS05260
-2.9
-6.1
ATP-grasp domain-containing protein
compare
MMJJ
_RS06855
-2.9
-1.8
DUF2104 domain-containing protein
compare
MMJJ
_RS06485
-2.9
-3.7
phosphoglycerate kinase
compare
MMJJ
_RS04975
-2.9
-3.1
glycosyltransferase family 4 protein
compare
MMJJ
_RS08000
-2.8
-9.8
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS04475
-2.8
-4.4
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS09175
-2.8
-2.0
anthranilate synthase component I
compare
MMJJ
_RS04595
-2.7
-7.8
hypothetical protein
compare
MMJJ
_RS00070
-2.7
-4.8
CooT family nickel-binding protein
compare
MMJJ
_RS04655
-2.7
-7.7
FAD-dependent oxidoreductase
compare
MMJJ
_RS06220
-2.7
-7.4
polyamine aminopropyltransferase
compare
MMJJ
_RS01345
-2.6
-4.0
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS07245
-2.6
-6.4
amidohydrolase family protein
compare
MMJJ
_RS05655
-2.6
-7.1
HisA/HisF family protein
compare
MMJJ
_RS03295
-2.6
-15.5
PHP domain-containing protein
compare
MMJJ
_RS07360
-2.6
-2.2
TIGR00269 family protein
compare
MMJJ
_RS08155
-2.6
-4.1
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS01830
-2.6
-4.3
tRNA(Ile)(2)-agmatinylcytidine synthase
compare
MMJJ
_RS04675
-2.6
-6.3
thiamine pyrophosphate-binding protein
compare
MMJJ
_RS05490
-2.6
-4.0
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS08855
-2.6
-5.0
cyclic pyranopterin monophosphate synthase MoaC
compare
MMJJ
_RS03190
-2.6
-3.7
phosphopyruvate hydratase
compare
MMJJ
_RS03065
-2.6
-12.0
CBS domain-containing protein
compare
MMJJ
_RS07660
-2.5
-12.0
carbonic anhydrase
compare
MMJJ
_RS07725
-2.5
-7.6
DNA primase DnaG
compare
MMJJ
_RS00645
-2.5
-11.1
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS02045
-2.5
-3.7
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS08005
-2.5
-14.4
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMJJ
_RS05330
-2.5
-2.8
DNA polymerase II large subunit
compare
MMJJ
_RS05810
-2.5
-7.0
precorrin-4 C(11)-methyltransferase
compare
MMJJ
_RS03125
-2.5
-4.9
GMC oxidoreductase
compare
MMJJ
_RS03660
-2.5
-4.5
DUF447 family protein
compare
MMJJ
_RS06750
-2.5
-2.4
homoaconitase large subunit
compare
MMJJ
_RS03820
-2.5
-4.1
hydrogenase formation protein HypD
compare
MMJJ
_RS00050
-2.5
-11.9
AAA family ATPase
compare
MMJJ
_RS08660
-2.5
-3.8
acetylornithine transaminase
compare
MMJJ
_RS08620
-2.4
-3.6
DUF373 family protein
compare
MMJJ
_RS06785
-2.4
-7.9
RNA ligase partner protein
compare
MMJJ
_RS00355
-2.4
-4.5
ribonuclease P protein component 4
compare
MMJJ
_RS06180
-2.4
-3.7
tryptophan--tRNA ligase
compare
MMJJ
_RS05065
-2.4
-3.4
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS00275
-2.4
-2.3
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS03830
-2.4
-10.6
CBS domain-containing protein
compare
MMJJ
_RS00040
-2.4
-10.1
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMJJ
_RS00045
-2.4
-15.6
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMJJ
_RS08535
-2.4
-4.2
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS01200
-2.3
-3.7
PRC-barrel domain-containing protein
compare
MMJJ
_RS04615
-2.3
-4.9
methanogenesis marker 3 protein
compare
MMJJ
_RS00055
-2.3
-9.1
CO dehydrogenase/acetyl-CoA synthase subunit delta
compare
MMJJ
_RS04790
-2.3
-3.9
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMJJ
_RS07350
-2.3
-4.4
4Fe-4S binding protein
compare
MMJJ
_RS00075
-2.3
-10.9
AAA family ATPase
compare
MMJJ
_RS03115
-2.3
-8.5
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS07155
-2.3
-9.6
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS04520
-2.3
-4.7
coenzyme F430 synthase
compare
MMJJ
_RS06270
-2.3
-9.6
dethiobiotin synthase
compare
MMJJ
_RS06760
-2.3
-5.2
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS07470
-2.3
-2.7
50S ribosome-binding GTPase
compare
MMJJ
_RS07275
-2.3
-3.7
formate--phosphoribosylaminoimidazolecarboxamide ligase
compare
MMJJ
_RS06110
-2.3
-2.9
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
compare
MMJJ
_RS03630
-2.3
-12.5
AMP phosphorylase
compare
MMJJ
_RS00370
-2.3
-2.6
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS06705
-2.3
-5.8
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS03895
-2.3
-2.7
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS05190
-2.2
-7.4
gamma carbonic anhydrase family protein
compare
MMJJ
_RS03200
-2.2
-3.1
uroporphyrinogen-III synthase
compare
MMJJ
_RS04730
-2.2
-3.8
tyrosine decarboxylase MfnA
compare
MMJJ
_RS00520
-2.2
-4.9
PDGLE domain-containing protein
compare
MMJJ
_RS00530
-2.2
-11.4
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07345
-2.2
-6.4
homocysteine biosynthesis protein
compare
MMJJ
_RS00060
-2.2
-14.9
acetyl-CoA decarbonylase/synthase complex subunit gamma
compare
MMJJ
_RS06185
-2.2
-5.2
cobalamin biosynthesis protein
compare
MMJJ
_RS07410
-2.2
-3.0
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS00035
-2.2
-14.3
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMJJ
_RS06700
-2.2
-4.7
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS04050
-2.2
-1.9
dihydroneopterin aldolase family protein
compare
MMJJ
_RS06835
-2.2
-10.0
4Fe-4S binding protein
compare
MMJJ
_RS08340
-2.2
-5.4
archaeoflavoprotein AfpA
compare
MMJJ
_RS07980
-2.2
-10.0
biotin synthase BioB
compare
MMJJ
_RS07190
-2.2
-4.4
RtcB family protein
compare
MMJJ
_RS07430
-2.1
-4.8
ribonuclease VapC
compare
MMJJ
_RS06865
-2.1
-3.0
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS02055
-2.1
-12.8
GTP 3',8-cyclase MoaA
compare
MMJJ
_RS00080
-2.1
-11.6
DUF166 domain-containing protein
compare
MMJJ
_RS08840
-2.1
-4.4
calcium/sodium antiporter
compare
MMJJ
_RS01565
-2.1
-8.8
TIGR00267 family protein
compare
MMJJ
_RS05360
-2.1
-6.1
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS03800
-2.1
-10.0
aldolase
compare
MMJJ
_RS04875
-2.1
-2.1
tRNA-Lys
compare
MMJJ
_RS05155
-2.1
-5.5
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS01360
-2.1
-2.7
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS07995
-2.1
-7.2
molybdenum cofactor biosynthesis protein MoaE
compare
MMJJ
_RS04985
-2.1
-3.9
glutamyl-tRNA reductase
compare
MMJJ
_RS06930
-2.1
-2.2
type II methionyl aminopeptidase
compare
MMJJ
_RS03055
-2.0
-4.0
hypothetical protein
compare
MMJJ
_RS05375
-2.0
-13.1
radical SAM protein
compare
MMJJ
_RS01410
-2.0
-5.4
archaeal proteasome endopeptidase complex subunit beta
compare
MMJJ
_RS00515
-2.0
-11.0
cobalt transporter CbiM
compare
MMJJ
_RS07355
-2.0
-4.2
MoaD/ThiS family protein
compare
MMJJ
_RS06250
-2.0
-2.5
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS07370
-2.0
-5.0
tRNA 4-thiouridine(8) synthase ThiI
compare
MMJJ
_RS01355
-2.0
-3.5
UDP-N-acetyl-D-mannosamine dehydrogenase
compare
MMJJ
_RS04650
-2.0
-5.9
nitrogenase iron protein
compare
MMJJ
_RS00215
-2.0
-3.3
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS04670
-2.0
-4.6
DUF2117 domain-containing protein
compare
MMJJ
_RS00600
-2.0
-3.1
hydroxymethylbilane synthase
compare
MMJJ
_RS08065
-2.0
-2.6
precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
compare
MMJJ
_RS06730
-2.0
-6.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS06155
-2.0
-5.5
phosphatidylglycerophosphatase A
compare
MMJJ
_RS03845
-1.9
-3.5
translation initiation factor IF-2
compare
MMJJ
_RS06375
-1.9
-5.2
UbiX family flavin prenyltransferase
compare
MMJJ
_RS00065
-1.9
-8.1
4Fe-4S dicluster domain-containing protein
compare
MMJJ
_RS05295
-1.9
-8.8
cobyrinic acid a,c-diamide synthase
compare
MMJJ
_RS08795
-1.9
-3.0
phosphoglucosamine mutase
compare
MMJJ
_RS06805
-1.9
-3.9
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS05935
-1.9
-2.5
Era-like GTP-binding protein
compare
MMJJ
_RS08095
-1.9
-4.3
cobyric acid synthase CobQ
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments