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Experiment set3IT034 for
Methanococcus maripaludis JJ
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formate McAA biotin dropout
200 most detrimental genes:
gene
name
fitness
t score
description
MMJJ
_RS04415
+2.6
11.7
hypothetical protein
compare
MMJJ
_RS07185
+1.0
2.0
DUF371 domain-containing protein
compare
MMJJ
_RS03725
+0.8
3.0
sulfurtransferase TusA family protein
compare
MMJJ
_RS04005
+0.7
5.4
acetate--CoA ligase family protein
compare
MMJJ
_RS08520
+0.7
2.1
peptidylprolyl isomerase
compare
MMJJ
_RS05685
+0.7
3.9
class III signal peptide-containing protein
compare
MMJJ
_RS07240
+0.7
5.8
MBL fold metallo-hydrolase
compare
MMJJ
_RS06680
+0.6
4.2
DUF366 family protein
compare
MMJJ
_RS08830
+0.6
2.8
hypothetical protein
compare
MMJJ
_RS04955
+0.6
4.1
tRNA pseudouridine(54/55) synthase Pus10
compare
MMJJ
_RS07005
+0.6
2.2
transcription factor S
compare
MMJJ
_RS08390
+0.6
1.4
carboxymuconolactone decarboxylase family protein
compare
MMJJ
_RS07765
+0.6
2.3
DMT family protein
compare
MMJJ
_RS06505
+0.6
2.0
prephenate dehydratase
compare
MMJJ
_RS07225
+0.5
3.8
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS07750
+0.5
1.4
class III signal peptide-containing protein
compare
MMJJ
_RS06675
+0.5
3.8
TIGR01212 family radical SAM protein
compare
MMJJ
_RS05915
+0.5
1.7
multiprotein bridging factor aMBF1
compare
MMJJ
_RS07235
+0.5
4.1
coenzyme F420 hydrogenase subunit alpha
compare
MMJJ
_RS07280
+0.5
3.0
phosphomannomutase/phosphoglucomutase
compare
MMJJ
_RS06460
+0.5
2.8
cytochrome c
compare
MMJJ
_RS01590
+0.5
1.3
adenine phosphoribosyltransferase
compare
MMJJ
_RS06275
+0.5
1.9
hypothetical protein
compare
MMJJ
_RS06190
+0.5
3.8
7-cyano-7-deazaguanine synthase
compare
MMJJ
_RS06535
+0.5
3.7
UPF0104 family protein
compare
MMJJ
_RS07220
+0.5
3.5
coenzyme F420 hydrogenase subunit beta
compare
MMJJ
_RS07025
+0.5
2.5
tRNA (cytidine(56)-2'-O)-methyltransferase
compare
MMJJ
_RS07920
+0.5
2.9
6-carboxytetrahydropterin synthase QueD
compare
MMJJ
_RS04545
+0.5
1.6
PadR family transcriptional regulator
compare
MMJJ
_RS07215
+0.4
3.5
TIGR00341 family protein
compare
MMJJ
_RS07450
+0.4
2.7
hypothetical protein
compare
MMJJ
_RS03835
+0.4
1.8
DUF504 domain-containing protein
compare
MMJJ
_RS05040
+0.4
3.4
7-carboxy-7-deazaguanine synthase QueE
compare
MMJJ
_RS06280
+0.4
3.2
hypothetical protein
compare
MMJJ
_RS05975
+0.4
2.7
sulfurtransferase TusA family protein
compare
MMJJ
_RS07210
+0.4
3.4
AmmeMemoRadiSam system protein B
compare
MMJJ
_RS06950
+0.4
3.2
4-demethylwyosine synthase TYW1
compare
MMJJ
_RS07365
+0.4
3.2
CatB-related O-acetyltransferase
compare
MMJJ
_RS03375
+0.4
2.4
hypothetical protein
compare
MMJJ
_RS06810
+0.4
3.3
L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
compare
MMJJ
_RS07230
+0.4
2.4
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS03350
+0.4
1.0
hypothetical protein
compare
MMJJ
_RS07270
+0.4
2.7
ribonuclease HII
compare
MMJJ
_RS01670
+0.4
1.4
hypothetical protein
compare
MMJJ
_RS04850
+0.4
2.1
energy-coupling factor transporter transmembrane protein EcfT
compare
MMJJ
_RS08100
+0.4
2.4
hypothetical protein
compare
MMJJ
_RS06975
+0.4
1.5
protein translocase SEC61 complex subunit gamma
compare
MMJJ
_RS06540
+0.4
1.1
DUF2120 domain-containing protein
compare
MMJJ
_RS08130
+0.4
0.4
translation initiation factor IF-2 subunit gamma
compare
MMJJ
_RS04340
+0.4
1.0
hypothetical protein
compare
MMJJ
_RS05520
+0.4
3.0
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMJJ
_RS05960
+0.4
2.4
DUF169 domain-containing protein
compare
MMJJ
_RS06960
+0.4
3.4
CAP domain-containing protein
compare
MMJJ
_RS06740
+0.4
2.1
energy-coupling factor ABC transporter substrate-binding protein
compare
MMJJ
_RS06500
+0.4
2.4
class I SAM-dependent methyltransferase
compare
MMJJ
_RS06515
+0.4
2.7
ribonuclease III
compare
MMJJ
_RS06210
+0.4
2.2
hypothetical protein
compare
MMJJ
_RS07480
+0.4
2.8
FAD-dependent oxidoreductase
compare
MMJJ
_RS06440
+0.4
2.4
DUF4870 domain-containing protein
compare
MMJJ
_RS06735
+0.3
2.6
cobalt ECF transporter T component CbiQ
compare
MMJJ
_RS07760
+0.3
1.8
GNAT family N-acetyltransferase
compare
MMJJ
_RS09300
+0.3
1.0
hypothetical protein
compare
MMJJ
_RS06770
+0.3
2.8
hypothetical protein
compare
MMJJ
_RS01825
+0.3
1.3
DNA repair and recombination protein RadB
compare
MMJJ
_RS07610
+0.3
1.9
DUF2119 domain-containing protein
compare
MMJJ
_RS06470
+0.3
2.3
tripartite tricarboxylate transporter permease
compare
MMJJ
_RS04965
+0.3
0.8
RNA polymerase Rpb4 family protein
compare
MMJJ
_RS01855
+0.3
2.5
MBL fold metallo-hydrolase
compare
MMJJ
_RS01010
+0.3
3.1
right-handed parallel beta-helix repeat-containing protein
compare
MMJJ
_RS07595
+0.3
1.6
hypothetical protein
compare
MMJJ
_RS07740
+0.3
2.1
DUF2334 domain-containing protein
compare
MMJJ
_RS06090
+0.3
1.8
hypothetical protein
compare
MMJJ
_RS04815
+0.3
1.3
TIM barrel protein
compare
MMJJ
_RS06585
+0.3
1.9
alanine racemase
compare
MMJJ
_RS04105
+0.3
2.7
prepilin peptidase
compare
MMJJ
_RS07200
+0.3
2.5
MFS transporter
compare
MMJJ
_RS05580
+0.3
2.0
methanogenesis marker 9 domain-containing protein
compare
MMJJ
_RS07495
+0.3
2.0
4Fe-4S binding protein
compare
MMJJ
_RS01395
+0.3
1.5
DUF1894 domain-containing protein
compare
MMJJ
_RS06430
+0.3
2.1
haloacid dehalogenase
compare
MMJJ
_RS06580
+0.3
2.3
alanine dehydrogenase
compare
MMJJ
_RS06640
+0.3
2.2
YfcE family phosphodiesterase
compare
MMJJ
_RS05530
+0.3
1.3
roadblock/LC7 domain-containing protein
compare
MMJJ
_RS06520
+0.3
2.0
TldD/PmbA family protein
compare
MMJJ
_RS06685
+0.3
2.6
S-layer protein
compare
MMJJ
_RS06285
+0.3
2.0
YchF/TatD family DNA exonuclease
compare
MMJJ
_RS07820
+0.3
2.3
bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
compare
MMJJ
_RS04135
+0.3
1.1
7-cyano-7-deazaguanine synthase QueC
compare
MMJJ
_RS00150
+0.3
1.8
DUF2180 family protein
compare
MMJJ
_RS02125
+0.3
0.9
hypothetical protein
compare
MMJJ
_RS04215
+0.3
2.3
DMT family transporter
compare
MMJJ
_RS09330
+0.3
1.5
hypothetical protein
compare
MMJJ
_RS06120
+0.3
1.9
DUF4013 domain-containing protein
compare
MMJJ
_RS06590
+0.3
2.2
sodium:alanine symporter family protein
compare
MMJJ
_RS06550
+0.3
2.1
ABC transporter permease
compare
MMJJ
_RS07205
+0.3
1.4
MTH895/ArsE family thioredoxin-like protein
compare
MMJJ
_RS05365
+0.3
1.5
DUF2798 domain-containing protein
compare
MMJJ
_RS05980
+0.3
1.7
DUF5400 domain-containing protein
compare
MMJJ
_RS02000
+0.3
1.4
AzlD domain-containing protein
compare
MMJJ
_RS08305
+0.3
1.5
peroxiredoxin
compare
MMJJ
_RS05400
+0.3
1.3
CoA-binding protein
compare
MMJJ
_RS06205
+0.3
1.9
EamA family transporter
compare
MMJJ
_RS03775
+0.3
0.9
50S ribosomal protein L15e
compare
MMJJ
_RS06290
+0.3
1.4
DUF749 domain-containing protein
compare
MMJJ
_RS07795
+0.3
1.7
cupin domain-containing protein
compare
MMJJ
_RS07915
+0.3
1.3
CBS domain-containing protein
compare
MMJJ
_RS00395
+0.3
1.2
DUF473 domain-containing protein
compare
MMJJ
_RS07825
+0.3
1.5
YciI family protein
compare
MMJJ
_RS08455
+0.3
1.4
tetratricopeptide repeat protein
compare
MMJJ
_RS00745
+0.3
1.2
hypothetical protein
compare
MMJJ
_RS09360
+0.3
1.7
hypothetical protein
compare
MMJJ
_RS05660
+0.3
1.4
sulfopyruvate decarboxylase subunit beta
compare
MMJJ
_RS05335
+0.3
1.2
heavy metal-binding domain-containing protein
compare
MMJJ
_RS07800
+0.3
2.2
AMP-binding protein
compare
MMJJ
_RS05245
+0.3
1.8
type II secretion system F family protein
compare
MMJJ
_RS07445
+0.3
1.8
RlmF-related methyltransferase
compare
MMJJ
_RS05700
+0.3
1.5
metallophosphoesterase
compare
MMJJ
_RS05355
+0.3
1.6
DUF2121 domain-containing protein
compare
MMJJ
_RS08015
+0.2
1.4
HAD family hydrolase
compare
MMJJ
_RS08935
+0.2
0.3
TIGR00288 family NYN domain-containing protein
compare
MMJJ
_RS01970
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS08285
+0.2
1.9
class I SAM-dependent methyltransferase
compare
MMJJ
_RS05510
+0.2
1.8
archaellum operon transcriptional activator EarA family protein
compare
MMJJ
_RS06765
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS08225
+0.2
0.8
peptidylprolyl isomerase
compare
MMJJ
_RS06085
+0.2
1.0
proteasome assembly chaperone family protein
compare
MMJJ
_RS07835
+0.2
1.6
UPF0489 family protein
compare
MMJJ
_RS05405
+0.2
1.9
DNA cytosine methyltransferase
compare
MMJJ
_RS07905
+0.2
1.8
DUF89 domain-containing protein
compare
MMJJ
_RS06455
+0.2
1.8
YeeE/YedE family protein
compare
MMJJ
_RS07890
+0.2
1.6
pyrimidine dimer DNA glycosylase/endonuclease V
compare
MMJJ
_RS05835
+0.2
1.9
bis-aminopropyl spermidine synthase family protein
compare
MMJJ
_RS09325
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS00890
+0.2
1.4
coenzyme F420 hydrogenase subunit gamma
compare
MMJJ
_RS06135
+0.2
1.8
50S ribosomal protein L11 methyltransferase
compare
MMJJ
_RS08370
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS07695
+0.2
1.9
glycoside hydrolase family 15 protein
compare
MMJJ
_RS06445
+0.2
2.0
hypothetical protein
compare
MMJJ
_RS05500
+0.2
2.1
hypothetical protein
compare
MMJJ
_RS08410
+0.2
0.8
CBS domain-containing protein
compare
MMJJ
_RS08675
+0.2
1.3
phosphate ABC transporter ATP-binding protein PstB
compare
MMJJ
_RS07260
+0.2
1.4
PspC domain-containing protein
compare
MMJJ
_RS04350
+0.2
0.7
hypothetical protein
compare
MMJJ
_RS06560
+0.2
1.7
site-2 protease family protein
compare
MMJJ
_RS06130
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS07685
+0.2
1.9
glycogen/starch synthase
compare
MMJJ
_RS05525
+0.2
1.3
GTP-binding protein
compare
MMJJ
_RS01530
+0.2
0.9
YwbE family protein
compare
MMJJ
_RS06710
+0.2
1.7
TldD/PmbA family protein
compare
MMJJ
_RS05085
+0.2
1.6
hypothetical protein
compare
MMJJ
_RS07860
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS02230
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS01955
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS03040
+0.2
1.4
lactate utilization protein
compare
MMJJ
_RS08630
+0.2
1.5
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMJJ
_RS00785
+0.2
0.5
hypothetical protein
compare
MMJJ
_RS01790
+0.2
1.4
pyridoxamine 5'-phosphate oxidase family protein
compare
MMJJ
_RS03720
+0.2
1.3
DsrE family protein
compare
MMJJ
_RS01405
+0.2
0.2
proline--tRNA ligase
compare
MMJJ
_RS05985
+0.2
1.3
ABC transporter substrate-binding protein
compare
MMJJ
_RS07790
+0.2
1.5
hypothetical protein
compare
MMJJ
_RS07985
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS06235
+0.2
1.6
IGHMBP2 family helicase
compare
MMJJ
_RS03395
+0.2
0.4
hypothetical protein
compare
MMJJ
_RS08375
+0.2
1.6
ferritin
compare
MMJJ
_RS05690
+0.2
1.8
hypothetical protein
compare
MMJJ
_RS07255
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS09005
+0.2
1.7
N-6 DNA methylase
compare
MMJJ
_RS06790
+0.2
1.6
nucleotidyltransferase family protein
compare
MMJJ
_RS03450
+0.2
0.9
hypothetical protein
compare
MMJJ
_RS03905
+0.2
1.2
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS09065
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS03025
+0.2
1.6
Ig-like domain-containing protein
compare
MMJJ
_RS03250
+0.2
0.5
DUF2116 family Zn-ribbon domain-containing protein
compare
MMJJ
_RS05340
+0.2
1.4
AAA family ATPase
compare
MMJJ
_RS07810
+0.2
1.2
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMJJ
_RS06045
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS02280
+0.2
1.3
sulfate permease
compare
MMJJ
_RS05990
+0.2
1.1
phosphatase PAP2 family protein
compare
MMJJ
_RS02310
+0.2
1.2
ABC transporter ATP-binding protein
compare
MMJJ
_RS01505
+0.2
0.8
DUF2124 domain-containing protein
compare
MMJJ
_RS00145
+0.2
1.3
aquaporin family protein
compare
MMJJ
_RS00635
+0.2
1.3
ABC transporter permease subunit
compare
MMJJ
_RS06465
+0.2
1.1
hypothetical protein
compare
MMJJ
_RS07815
+0.2
1.2
2-oxoacid:acceptor oxidoreductase family protein
compare
MMJJ
_RS03715
+0.2
1.3
hypothetical protein
compare
MMJJ
_RS08210
+0.2
1.7
hypothetical protein
compare
MMJJ
_RS00100
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS02160
+0.2
1.3
amino acid ABC transporter permease
compare
MMJJ
_RS00155
+0.2
1.4
DUF2193 domain-containing protein
compare
MMJJ
_RS05965
+0.2
1.4
MFS transporter
compare
MMJJ
_RS05410
+0.2
1.0
RecB-family nuclease
compare
MMJJ
_RS07385
+0.2
1.3
ribosomal protein S18-alanine N-acetyltransferase
compare
MMJJ
_RS08165
+0.2
0.9
thermonuclease family protein
compare
MMJJ
_RS05885
+0.2
1.4
tungstate ABC transporter substrate-binding protein WtpA
compare
MMJJ
_RS07830
+0.2
1.2
DUF1786 domain-containing protein
compare
MMJJ
_RS03355
+0.2
1.2
hypothetical protein
compare
MMJJ
_RS07855
+0.2
1.3
YkgJ family cysteine cluster protein
compare
MMJJ
_RS00790
+0.2
0.8
ribonuclease H family protein
compare
MMJJ
_RS07745
+0.2
1.4
DUF5814 domain-containing protein
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis JJ in nutrient t1 experiments