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Experiment set3IT033 for
Methanococcus maripaludis S2
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H2 McCas, 5g/L bicarb, 40 psi H2CO2
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS07645
-10.1
-4.8
aldehyde dehydrogenase family protein
compare
MMP
_RS07845
-9.8
-3.4
LL-diaminopimelate aminotransferase
compare
MMP
_RS06395
-9.1
-3.6
ThiF family adenylyltransferase
compare
MMP
_RS06350
-9.1
-6.2
HesA/MoeB/ThiF family protein
compare
MMP
_RS08440
-8.3
-3.6
cell division protein SepF
compare
MMP
_RS01225
-8.2
-4.8
DUF5379 domain-containing protein
compare
MMP
_RS00735
-7.8
-3.5
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS08820
-7.8
-6.4
hypothetical protein
compare
MMP
_RS00915
-7.6
-8.5
DUF116 domain-containing protein
compare
MMP
_RS00730
-7.6
-6.0
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
compare
MMP
_RS01175
-7.5
-5.5
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS08435
-7.5
-2.9
Era-like GTP-binding protein
compare
MMP
_RS06625
-7.5
-2.9
DNA primase
compare
MMP
_RS04850
-7.4
-25.1
UPF0254 family protein
compare
MMP
_RS07390
-7.2
-3.5
cell division protein FtsZ
compare
MMP
_RS08100
-7.2
-8.1
8-amino-7-oxononanoate synthase
compare
MMP
_RS03015
-7.1
-11.3
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06355
-7.1
-3.0
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS00810
-7.1
-9.9
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS00520
-7.1
-2.4
RNA polymerase Rpb4 family protein
compare
MMP
_RS05930
-7.1
-3.1
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS00725
-7.1
-9.0
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS04710
-7.0
-2.4
hypothetical protein
compare
MMP
_RS04500
-7.0
-18.6
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS08210
-7.0
-2.7
phosphatidylglycerophosphatase A
compare
MMP
_RS07635
-6.9
-8.2
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS05515
-6.9
-6.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS01795
-6.8
-2.3
methanogenesis marker 6 protein
compare
MMP
_RS07695
-6.8
-7.2
DUF3236 domain-containing protein
compare
MMP
_RS06105
-6.7
-13.2
hydrogenase maturation peptidase HycI
compare
MMP
_RS08095
-6.7
-8.1
dethiobiotin synthase
compare
MMP
_RS07195
-6.6
-8.7
M20 family metallo-hydrolase
compare
MMP
_RS06400
-6.6
-2.2
4Fe-4S binding protein
compare
MMP
_RS06370
-6.4
-5.2
biotin synthase BioB
compare
MMP
_RS02875
-6.4
-11.3
chorismate pyruvate-lyase family protein
compare
MMP
_RS04685
-6.4
-4.5
DUF126 domain-containing protein
compare
MMP
_RS05845
-6.2
-2.4
tRNA-intron lyase
compare
MMP
_RS08195
-6.2
-12.0
hypothetical protein
compare
MMP
_RS07820
-6.1
-6.0
UPF0104 family protein
compare
MMP
_RS08650
-6.1
-3.6
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS01020
-6.1
-1.2
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS00315
-6.1
-7.6
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS00110
-6.0
-3.8
hypothetical protein
compare
MMP
_RS08320
-6.0
-7.9
molybdopterin molybdotransferase MoeA
compare
MMP
_RS08745
-6.0
-5.9
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS06885
-6.0
-3.9
50S ribosome-binding GTPase
compare
MMP
_RS08105
-6.0
-7.5
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS03400
-6.0
-4.1
archease
compare
MMP
_RS09020
-5.9
-2.8
hypothetical protein
compare
MMP
_RS03315
-5.9
-2.0
ferrous iron transport protein A
compare
MMP
_RS07700
-5.9
-12.6
DUF1188 domain-containing protein
compare
MMP
_RS03025
-5.8
-8.4
molybdenum cofactor guanylyltransferase
compare
MMP
_RS01380
-5.8
-4.8
PHP domain-containing protein
compare
MMP
_RS05265
-5.8
-2.8
2-isopropylmalate synthase
compare
MMP
_RS06120
-5.8
-2.9
UPF0147 family protein
compare
MMP
_RS06925
-5.8
-3.4
ribonuclease VapC4
compare
MMP
_RS07380
-5.7
-3.5
transcription elongation factor Spt5
compare
MMP
_RS06020
-5.7
-6.8
archaeoflavoprotein AfpA
compare
MMP
_RS07200
-5.7
-9.0
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS07750
-5.7
-7.2
DUF357 domain-containing protein
compare
MMP
_RS05640
-5.7
-9.1
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS03435
-5.6
-2.7
ketol-acid reductoisomerase
compare
MMP
_RS07630
-5.6
-1.9
ATP-binding cassette domain-containing protein
compare
MMP
_RS04780
-5.6
-3.1
ribonuclease P
compare
MMP
_RS02240
-5.5
-4.3
methanogenesis marker 7 protein
compare
MMP
_RS01830
-5.5
-1.5
tRNA-Val
compare
MMP
_RS00895
-5.5
-5.6
hypothetical protein
compare
MMP
_RS03580
-5.5
-4.5
signal recognition particle-docking protein FtsY
compare
MMP
_RS03600
-5.4
-3.2
triose-phosphate isomerase
compare
MMP
_RS06270
-5.4
-7.7
TIGR00300 family protein
compare
MMP
_RS02280
-5.4
-1.1
DUF211 domain-containing protein
compare
MMP
_RS01005
-5.4
-1.5
riboflavin synthase
compare
MMP
_RS00300
-5.3
-1.0
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS05425
-5.3
-6.4
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS00685
-5.2
-6.2
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS08715
-5.2
-2.8
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS03700
-5.2
-14.1
sodium:proton antiporter
compare
MMP
_RS05440
-5.2
-10.0
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS08720
-5.1
-2.0
4Fe-4S binding protein
compare
MMP
_RS06980
-5.1
-10.8
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS07755
-5.1
-1.4
DUF555 domain-containing protein
compare
MMP
_RS08460
-5.1
-3.2
proteasome-activating nucleotidase
compare
MMP
_RS03960
-5.1
-1.4
hypothetical protein
compare
MMP
_RS00305
-5.1
-3.0
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS08635
-5.0
-2.4
UbiA family prenyltransferase
compare
MMP
_RS08300
-5.0
-1.7
metal-sulfur cluster assembly factor
compare
MMP
_RS03475
-5.0
-1.0
hypothetical protein
compare
MMP
_RS00115
-5.0
-11.0
radical SAM protein
compare
MMP
_RS05550
-5.0
-1.0
cation:proton antiporter
compare
MMP
_RS01325
-4.9
-3.0
dihydroneopterin aldolase family protein
compare
MMP
_RS01220
-4.9
-10.9
hypothetical protein
compare
MMP
_RS03110
-4.9
-9.2
glycosyltransferase family 2 protein
compare
MMP
_RS03640
-4.9
-5.2
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS07555
-4.9
-1.0
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS02900
-4.9
-0.9
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS01500
-4.8
-3.4
CBS domain-containing protein
compare
MMP
_RS07005
-4.8
-0.9
4Fe-4S binding protein
compare
MMP
_RS06895
-4.8
-2.4
selenocysteine-specific translation elongation factor
compare
MMP
_RS04775
-4.8
-4.7
adenosylhomocysteinase
compare
MMP
_RS07600
-4.8
-3.2
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS06295
-4.8
-8.9
methanogenesis marker 14 protein
compare
MMP
_RS01725
-4.7
-5.0
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS08790
-4.7
-3.3
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS02010
-4.7
-14.0
PHP domain-containing protein
compare
MMP
_RS02345
-4.7
-5.4
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS06630
-4.7
-1.3
UPF0058 family protein
compare
MMP
_RS04615
-4.7
-4.0
PDGLE domain-containing protein
compare
MMP
_RS07730
-4.7
-2.8
pyruvate synthase subunit beta
compare
MMP
_RS06670
-4.7
-7.0
glucose-6-phosphate isomerase
compare
MMP
_RS02800
-4.6
-7.2
nucleotidyltransferase domain-containing protein
compare
MMP
_RS00515
-4.6
-1.3
DUF655 domain-containing protein
compare
MMP
_RS01800
-4.6
-5.4
TIGR00303 family protein
compare
MMP
_RS06900
-4.5
-3.8
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS06285
-4.5
-3.0
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS03035
-4.5
-5.5
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS08350
-4.5
-1.2
hypothetical protein
compare
MMP
_RS03445
-4.4
-1.5
methanogenesis marker 17 protein
compare
MMP
_RS06230
-4.4
-3.8
helix-turn-helix domain-containing protein
compare
MMP
_RS07075
-4.4
-5.1
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS01755
-4.4
-1.7
DUF2097 domain-containing protein
compare
MMP
_RS08365
-4.4
-5.4
energy conserving hydrogenase EhbF
compare
MMP
_RS06110
-4.3
-3.6
ATP-dependent protease LonB
compare
MMP
_RS07580
-4.3
-3.7
DUF356 domain-containing protein
compare
MMP
_RS03390
-4.3
-8.9
malate dehydrogenase
compare
MMP
_RS01915
-4.3
-16.7
DUF354 domain-containing protein
compare
MMP
_RS01865
-4.3
-2.1
GPR1/FUN34/YaaH family transporter
compare
MMP
_RS08355
-4.3
-7.8
Na(+)/H(+) antiporter subunit B
compare
MMP
_RS01700
-4.3
-1.2
dihydroxy-acid dehydratase
compare
MMP
_RS04720
-4.3
-4.6
DedA family protein
compare
MMP
_RS05250
-4.3
-3.2
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS08445
-4.2
-4.5
DUF2099 family protein
compare
MMP
_RS05555
-4.2
-1.6
DUF4040 domain-containing protein
compare
MMP
_RS08360
-4.2
-4.7
hypothetical protein
compare
MMP
_RS06685
-4.1
-13.4
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS01955
-4.1
-2.9
hypothetical protein
compare
MMP
_RS05815
-4.1
-3.5
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS04890
-4.0
-1.1
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS07525
-4.0
-6.8
4Fe-4S binding protein
compare
MMP
_RS01495
-4.0
-10.8
TraB/GumN family protein
compare
MMP
_RS01265
-3.9
-2.8
hypothetical protein
compare
MMP
_RS01335
-3.9
-1.9
prefoldin subunit beta
compare
MMP
_RS02885
-3.8
-19.8
molybdopterin biosynthesis protein
compare
MMP
_RS01650
-3.8
-1.0
sulfurtransferase TusA family protein
compare
MMP
_RS03205
-3.8
-2.1
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS01905
-3.8
-15.5
glycosyltransferase
compare
MMP
_RS04620
-3.7
-15.3
cobalt transporter CbiM
compare
MMP
_RS01900
-3.6
-18.7
hypothetical protein
compare
MMP
_RS02135
-3.6
-5.4
DUF5612 domain-containing protein
compare
MMP
_RS07330
-3.6
-17.4
membrane protein
compare
MMP
_RS05635
-3.6
-13.6
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS05925
-3.6
-5.4
small nuclear ribonucleoprotein
compare
MMP
_RS05500
-3.5
-10.4
2-isopropylmalate synthase
compare
MMP
_RS01910
-3.5
-12.4
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS01385
-3.5
-1.0
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS06315
-3.5
-1.3
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS07875
-3.5
-8.2
hypothetical protein
compare
MMP
_RS01895
-3.4
-13.1
flippase
compare
MMP
_RS03095
-3.4
-7.6
diphthine synthase
compare
MMP
_RS06730
-3.4
-2.5
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS01840
-3.4
-8.1
TIGR00289 family protein
compare
MMP
_RS02195
-3.4
-3.7
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS01925
-3.4
-8.9
DUF1616 domain-containing protein
compare
MMP
_RS04605
-3.3
-7.0
cobalt ECF transporter T component CbiQ
compare
MMP
_RS04870
-3.3
-5.7
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS01545
-3.3
-1.5
CBS domain-containing protein
compare
MMP
_RS07445
-3.3
-4.5
helix-turn-helix domain-containing protein
compare
MMP
_RS02110
-3.2
-2.3
hypothetical protein
compare
MMP
_RS01890
-3.2
-4.9
nucleotide sugar dehydrogenase
compare
MMP
_RS04875
-3.2
-5.0
energy-converting hydrogenase B subunit P
compare
MMP
_RS03155
-3.2
-8.5
precorrin-6A reductase
compare
MMP
_RS06130
-3.2
-4.7
peptidylprolyl isomerase
compare
MMP
_RS00695
-3.1
-1.2
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS07355
-3.1
-1.2
transcription factor S
compare
MMP
_RS02145
-3.1
-7.9
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05345
-3.1
-7.6
hypothetical protein
compare
MMP
_RS06725
-3.1
-12.3
hypothetical protein
compare
MMP
_RS02355
-3.0
-4.3
30S ribosomal protein S27ae
compare
MMP
_RS01880
-3.0
-8.3
DegT/DnrJ/EryC1/StrS family aminotransferase
compare
MMP
_RS07605
-3.0
-4.5
diadenylate cyclase
compare
MMP
_RS08330
-2.9
-4.3
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS05920
-2.9
-1.0
50S ribosomal protein L37e
compare
MMP
_RS07420
-2.9
-4.2
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS06475
-2.9
-5.9
FAD-dependent oxidoreductase
compare
MMP
_RS07425
-2.8
-5.3
GTP-binding protein
compare
MMP
_RS01610
-2.8
-5.1
hypothetical protein
compare
MMP
_RS00985
-2.7
-6.6
CDC48 family AAA ATPase
compare
MMP
_RS08370
-2.7
-0.9
cation:proton antiporter subunit C
compare
MMP
_RS07545
-2.7
-1.3
HTH domain-containing protein
compare
MMP
_RS01920
-2.7
-12.2
glycosyltransferase family 2 protein
compare
MMP
_RS03485
-2.7
-5.3
TIGR00267 family protein
compare
MMP
_RS01365
-2.7
-3.0
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS06340
-2.7
-8.5
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS07795
-2.7
-10.6
site-2 protease family protein
compare
MMP
_RS01875
-2.7
-10.5
N-acetyltransferase
compare
MMP
_RS01775
-2.6
-3.1
TIGR00297 family protein
compare
MMP
_RS01960
-2.6
-0.7
hypothetical protein
compare
MMP
_RS04585
-2.6
-12.7
AIR synthase related protein
compare
MMP
_RS01445
-2.6
-5.2
hypothetical protein
compare
MMP
_RS07735
-2.6
-1.0
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01885
-2.6
-7.9
Gfo/Idh/MocA family oxidoreductase
compare
Specific Phenotypes
For 9 genes in this experiment