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Experiment set3IT033 for
Methanococcus maripaludis S2
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H2 McCas, 5g/L bicarb, 40 psi H2CO2
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS01280
+1.9
15.5
DUF515 domain-containing protein
compare
MMP
_RS01290
+1.7
13.3
class III signal peptide-containing protein
compare
MMP
_RS01285
+1.7
12.1
hypothetical protein
compare
MMP
_RS01305
+1.6
14.1
hypothetical protein
compare
MMP
_RS01315
+1.6
14.6
DUF2341 domain-containing protein
compare
MMP
_RS01310
+1.6
12.6
hypothetical protein
compare
MMP
_RS00240
+1.6
13.4
type II secretion system F family protein
compare
MMP
_RS01295
+1.5
10.8
hypothetical protein
compare
MMP
_RS08860
+1.5
9.2
MinD/ParA family protein
compare
MMP
_RS08855
+1.4
8.9
hypothetical protein
compare
MMP
_RS00245
+1.4
11.2
type II secretion system F family protein
compare
MMP
_RS01275
+1.4
7.7
class III signal peptide-containing protein
compare
MMP
_RS06485
+1.4
2.2
zinc ribbon domain-containing protein
compare
MMP
_RS07815
+1.3
2.5
DUF2120 domain-containing protein
compare
MMP
_RS01270
+1.3
8.8
prepilin peptidase
compare
MMP
_RS00250
+1.1
9.0
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS03125
+1.1
6.4
cell division ATPase MinD
compare
MMP
_RS09045
+0.9
6.0
class III signal peptide-containing protein
compare
MMP
_RS08675
+0.9
1.4
class III signal peptide-containing protein
compare
MMP
_RS08845
+0.8
6.0
archaellum operon transcriptional activator EarA family protein
compare
MMP
_RS06540
+0.8
1.3
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS09055
+0.8
1.1
CAP domain-containing protein
compare
MMP
_RS01195
+0.8
1.3
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS08615
+0.8
1.3
flagellar protein G
compare
MMP
_RS07415
+0.8
3.5
molybdopterin-guanine dinucleotide biosynthesis protein MobB
compare
MMP
_RS00140
+0.7
2.8
DUF192 domain-containing protein
compare
MMP
_RS06860
+0.7
1.8
4Fe-4S binding protein
compare
MMP
_RS06935
+0.7
3.6
protease complex subunit PrcB family protein
compare
MMP
_RS01300
+0.7
6.2
hypothetical protein
compare
MMP
_RS08850
+0.7
5.8
hypothetical protein
compare
MMP
_RS05985
+0.7
2.2
hypothetical protein
compare
MMP
_RS06555
+0.7
2.1
cupin domain-containing protein
compare
MMP
_RS05905
+0.7
3.6
undecaprenyl-diphosphate phosphatase
compare
MMP
_RS05865
+0.6
2.3
hypothetical protein
compare
MMP
_RS08380
+0.6
2.6
phosphatase PAP2 family protein
compare
MMP
_RS08750
+0.6
1.6
hypothetical protein
compare
MMP
_RS07345
+0.6
3.2
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS06710
+0.6
3.0
selenium-binding protein
compare
MMP
_RS02170
+0.6
2.6
CBS domain-containing protein
compare
MMP
_RS08415
+0.6
1.9
radical SAM protein
compare
MMP
_RS01675
+0.6
1.3
hypothetical protein
compare
MMP
_RS01085
+0.6
1.3
hypothetical protein
compare
MMP
_RS08290
+0.6
4.0
DNA-binding protein Alba
compare
MMP
_RS06115
+0.6
3.8
class II aldolase/adducin family protein
compare
MMP
_RS03320
+0.6
1.8
metal-dependent transcriptional regulator
compare
MMP
_RS08455
+0.6
2.5
multiprotein bridging factor aMBF1
compare
MMP
_RS02550
+0.6
1.9
helix-turn-helix transcriptional regulator
compare
MMP
_RS07905
+0.5
1.9
DUF3343 domain-containing protein
compare
MMP
_RS08830
+0.5
2.7
GTP-binding protein
compare
MMP
_RS04610
+0.5
1.6
Dabb family protein
compare
MMP
_RS02415
+0.5
1.4
site-specific integrase
compare
MMP
_RS07895
+0.5
1.8
cytochrome c
compare
MMP
_RS08580
+0.5
1.6
flagellin
compare
MMP
_RS08265
+0.5
2.7
rubrerythrin
compare
MMP
_RS01110
+0.5
1.7
FmdE family protein
compare
MMP
_RS05785
+0.5
4.5
ATP-binding protein
compare
MMP
_RS04410
+0.5
1.9
hypothetical protein
compare
MMP
_RS04055
+0.5
1.0
hypothetical protein
compare
MMP
_RS08225
+0.5
2.2
RimK family alpha-L-glutamate ligase
compare
MMP
_RS01075
+0.5
1.2
hypothetical protein
compare
MMP
_RS08660
+0.5
2.5
DHH family phosphoesterase
compare
MMP
_RS08485
+0.5
3.6
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS06930
+0.5
2.7
MBL fold metallo-hydrolase
compare
MMP
_RS07835
+0.5
1.1
TldD/PmbA family protein
compare
MMP
_RS03215
+0.5
3.0
MBL fold metallo-hydrolase
compare
MMP
_RS08090
+0.5
1.6
hypothetical protein
compare
MMP
_RS06905
+0.5
1.0
hypothetical protein
compare
MMP
_RS03795
+0.5
2.9
YqhA family protein
compare
MMP
_RS05660
+0.5
1.9
phosphate ABC transporter substrate-binding protein
compare
MMP
_RS08500
+0.5
2.4
pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
compare
MMP
_RS05715
+0.5
2.8
hypothetical protein
compare
MMP
_RS06520
+0.5
1.7
DUF1786 domain-containing protein
compare
MMP
_RS08130
+0.4
3.1
IGHMBP2 family helicase
compare
MMP
_RS08285
+0.4
2.8
serine/threonine protein kinase
compare
MMP
_RS08070
+0.4
2.5
DUF2096 domain-containing protein
compare
MMP
_RS02045
+0.4
0.8
tRNA-Met
compare
MMP
_RS01125
+0.4
2.6
thioredoxin family protein
compare
MMP
_RS05975
+0.4
0.8
hypothetical protein
compare
MMP
_RS01570
+0.4
0.8
hypothetical protein
compare
MMP
_RS07805
+0.4
2.5
ABC transporter permease
compare
MMP
_RS06100
+0.4
2.8
GNAT family N-acetyltransferase
compare
MMP
_RS06305
+0.4
3.0
transporter substrate-binding domain-containing protein
compare
MMP
_RS07840
+0.4
1.3
ribonuclease III
compare
MMP
_RS08075
+0.4
2.1
DUF749 domain-containing protein
compare
MMP
_RS09030
+0.4
2.3
hypothetical protein
compare
MMP
_RS06585
+0.4
0.9
DMT family protein
compare
MMP
_RS00655
+0.4
1.5
hypothetical protein
compare
MMP
_RS00690
+0.4
2.2
MBL fold metallo-hydrolase
compare
MMP
_RS07590
+0.4
3.1
hypothetical protein
compare
MMP
_RS06190
+0.4
2.6
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
compare
MMP
_RS07115
+0.4
1.8
MBL fold metallo-hydrolase
compare
MMP
_RS08280
+0.4
1.2
proteasome assembly chaperone family protein
compare
MMP
_RS01685
+0.4
1.3
indolepyruvate oxidoreductase subunit beta
compare
MMP
_RS05990
+0.4
1.8
DsrE family protein
compare
MMP
_RS08310
+0.4
0.9
TMEM165/GDT1 family protein
compare
MMP
_RS07800
+0.4
1.8
ATP-binding cassette domain-containing protein
compare
MMP
_RS05235
+0.4
2.5
exodeoxyribonuclease III
compare
MMP
_RS02745
+0.4
1.1
hypothetical protein
compare
MMP
_RS03755
+0.4
2.8
MarR family transcriptional regulator
compare
MMP
_RS01450
+0.4
2.2
tRNA pseudouridine(38-40) synthase TruA
compare
MMP
_RS00535
+0.4
1.3
TIGR00375 family protein
compare
MMP
_RS01630
+0.4
1.9
N-glycosylase/DNA lyase
compare
MMP
_RS05130
+0.4
3.1
DUF2226 domain-containing protein
compare
MMP
_RS08570
+0.3
2.1
coenzyme F420-0:L-glutamate ligase
compare
MMP
_RS06700
+0.3
2.2
hypothetical protein
compare
MMP
_RS08160
+0.3
2.3
EamA family transporter
compare
MMP
_RS07855
+0.3
2.3
class I SAM-dependent methyltransferase
compare
MMP
_RS06660
+0.3
1.8
glycosyltransferase family 4 protein
compare
MMP
_RS08260
+0.3
2.4
DUF99 family protein
compare
MMP
_RS06250
+0.3
2.2
hypothetical protein
compare
MMP
_RS05780
+0.3
2.5
multidrug resistance efflux transporter family protein
compare
MMP
_RS05970
+0.3
1.5
class II SORL domain-containing protein
compare
MMP
_RS06655
+0.3
2.5
glycoside hydrolase family 15 protein
compare
MMP
_RS04145
+0.3
0.7
hypothetical protein
compare
MMP
_RS06545
+0.3
1.1
ferredoxin family protein
compare
MMP
_RS00120
+0.3
1.2
LysR family transcriptional regulator
compare
MMP
_RS01320
+0.3
2.2
hypothetical protein
compare
MMP
_RS04125
+0.3
1.9
TetR/AcrR family transcriptional regulator
compare
MMP
_RS07985
+0.3
2.3
nitroreductase family protein
compare
MMP
_RS06050
+0.3
2.0
ZIP family metal transporter
compare
MMP
_RS04100
+0.3
1.3
hypothetical protein
compare
MMP
_RS00400
+0.3
2.0
tributyrin esterase
compare
MMP
_RS00530
+0.3
2.1
tRNA pseudouridine(54/55) synthase Pus10
compare
MMP
_RS03220
+0.3
1.0
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS01790
+0.3
2.2
restriction endonuclease
compare
MMP
_RS06990
+0.3
1.8
CatB-related O-acetyltransferase
compare
MMP
_RS03625
+0.3
2.0
cell wall-binding protein
compare
MMP
_RS06465
+0.3
2.7
NERD domain-containing protein
compare
MMP
_RS06440
+0.3
1.2
CBS domain-containing protein
compare
MMP
_RS00540
+0.3
2.0
PLP-dependent aminotransferase family protein
compare
MMP
_RS06490
+0.3
1.5
hypothetical protein
compare
MMP
_RS02295
+0.3
2.0
TatD family hydrolase
compare
MMP
_RS01255
+0.3
1.6
amino acid ABC transporter ATP-binding protein
compare
MMP
_RS07715
+0.3
2.4
YfcE family phosphodiesterase
compare
MMP
_RS05140
+0.3
1.2
helix-turn-helix transcriptional regulator
compare
MMP
_RS03300
+0.3
0.3
TOBE domain-containing protein
compare
MMP
_RS07150
+0.3
1.3
MTH895/ArsE family thioredoxin-like protein
compare
MMP
_RS08395
+0.3
1.4
DsrE family protein
compare
MMP
_RS06005
+0.3
1.4
heavy-metal-associated domain-containing protein
compare
MMP
_RS06185
+0.3
1.4
thermonuclease family protein
compare
MMP
_RS03490
+0.3
0.7
DUF2115 domain-containing protein
compare
MMP
_RS07640
+0.3
1.5
mechanosensitive ion channel family protein
compare
MMP
_RS02425
+0.3
1.9
hypothetical protein
compare
MMP
_RS08980
+0.3
1.2
hypothetical protein
compare
MMP
_RS06705
+0.3
1.8
formate/nitrite transporter family protein
compare
MMP
_RS09060
+0.3
2.4
hypothetical protein
compare
MMP
_RS02530
+0.3
1.7
type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family
compare
MMP
_RS06225
+0.3
1.3
DNA double-strand break repair nuclease NurA
compare
MMP
_RS08080
+0.3
1.6
YchF/TatD family DNA exonuclease
compare
MMP
_RS06445
+0.3
1.7
DUF89 domain-containing protein
compare
MMP
_RS01635
+0.3
2.0
thiamine pyrophosphate-dependent enzyme
compare
MMP
_RS05645
+0.3
1.8
AEC family transporter
compare
MMP
_RS05995
+0.3
2.2
FprA family A-type flavoprotein
compare
MMP
_RS01135
+0.3
2.0
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS05315
+0.3
0.6
hypothetical protein
compare
MMP
_RS02260
+0.3
1.8
lactate utilization protein
compare
MMP
_RS03685
+0.3
1.8
Mrp/NBP35 family ATP-binding protein
compare
MMP
_RS08480
+0.3
1.8
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS08315
+0.3
0.8
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS08385
+0.3
1.4
ABC transporter substrate-binding protein
compare
MMP
_RS04735
+0.3
1.6
tautomerase family protein
compare
MMP
_RS08835
+0.3
1.1
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS05435
+0.3
1.5
5'/3'-nucleotidase SurE
compare
MMP
_RS06145
+0.3
2.4
hypothetical protein
compare
MMP
_RS05125
+0.3
1.8
D-aminoacyl-tRNA deacylase
compare
MMP
_RS04190
+0.3
1.5
hypothetical protein
compare
MMP
_RS08405
+0.3
1.4
MFS transporter
compare
MMP
_RS06045
+0.3
2.0
DNA polymerase
compare
MMP
_RS06085
+0.3
2.2
iron ABC transporter substrate-binding protein
compare
MMP
_RS00085
+0.3
2.1
DNA cytosine methyltransferase
compare
MMP
_RS06300
+0.3
1.6
ABC transporter substrate-binding protein
compare
MMP
_RS01260
+0.3
0.9
HDIG domain-containing protein
compare
MMP
_RS08665
+0.3
2.2
hypothetical protein
compare
MMP
_RS06280
+0.3
1.3
alpha-glucan family phosphorylase
compare
MMP
_RS06735
+0.3
1.1
class I SAM-dependent rRNA methyltransferase
compare
MMP
_RS06910
+0.3
1.4
RlmF-related methyltransferase
compare
MMP
_RS07595
+0.3
2.0
hypothetical protein
compare
MMP
_RS06560
+0.3
2.0
hypothetical protein
compare
MMP
_RS08245
+0.3
1.3
DUF4013 domain-containing protein
compare
MMP
_RS08390
+0.2
1.2
DUF5400 domain-containing protein
compare
MMP
_RS08610
+0.2
1.8
flagellar protein F
compare
MMP
_RS00395
+0.2
0.5
MGMT family protein
compare
MMP
_RS01680
+0.2
1.7
phenylacetate--CoA ligase
compare
MMP
_RS02645
+0.2
1.2
ArsR family transcriptional regulator
compare
MMP
_RS00625
+0.2
0.9
hypothetical protein
compare
MMP
_RS08685
+0.2
2.0
hypothetical protein
compare
MMP
_RS08250
+0.2
1.3
pyruvate kinase
compare
MMP
_RS08325
+0.2
1.6
hypothetical protein
compare
MMP
_RS08640
+0.2
1.5
TIM barrel protein
compare
MMP
_RS05155
+0.2
1.2
hypothetical protein
compare
MMP
_RS03820
+0.2
1.3
EamA family transporter
compare
MMP
_RS02320
+0.2
1.4
glutamate-cysteine ligase family protein
compare
MMP
_RS02500
+0.2
1.5
minichromosome maintenance protein MCM
compare
MMP
_RS03875
+0.2
0.7
hypothetical protein
compare
MMP
_RS06965
+0.2
1.1
TIGR04014 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS07085
+0.2
1.3
ribonuclease HII
compare
MMP
_RS01055
+0.2
0.9
hypothetical protein
compare
MMP
_RS02255
+0.2
1.4
hypothetical protein
compare
MMP
_RS02810
+0.2
1.5
hypothetical protein
compare
MMP
_RS05020
+0.2
0.7
hypothetical protein
compare
Specific Phenotypes
For 9 genes in this experiment