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Experiment set3IT022 for
Methanococcus maripaludis S2
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H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS06355
-9.1
-3.5
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS05280
-8.0
-13.4
COG1361 S-layer family protein
compare
MMP
_RS06120
-7.5
-3.2
UPF0147 family protein
compare
MMP
_RS07845
-7.1
-3.5
LL-diaminopimelate aminotransferase
compare
MMP
_RS04710
-6.8
-2.6
hypothetical protein
compare
MMP
_RS01500
-6.6
-3.3
CBS domain-containing protein
compare
MMP
_RS06400
-6.6
-2.5
4Fe-4S binding protein
compare
MMP
_RS06730
-6.5
-2.9
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS07600
-6.4
-3.6
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS05285
-6.3
-8.9
MMPL family transporter
compare
MMP
_RS05515
-6.3
-7.6
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS04720
-6.3
-4.6
DedA family protein
compare
MMP
_RS06350
-6.3
-7.8
HesA/MoeB/ThiF family protein
compare
MMP
_RS03400
-6.2
-3.9
archease
compare
MMP
_RS08820
-6.2
-8.3
hypothetical protein
compare
MMP
_RS06900
-6.1
-4.1
coenzyme F420-reducing hydrogenase FrhD protein
compare
MMP
_RS06285
-6.0
-3.5
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS03025
-6.0
-8.2
molybdenum cofactor guanylyltransferase
compare
MMP
_RS08460
-6.0
-3.2
proteasome-activating nucleotidase
compare
MMP
_RS03015
-5.9
-11.3
GTP 3' 8-cyclase MoaA
compare
MMP
_RS09020
-5.9
-3.1
hypothetical protein
compare
MMP
_RS02875
-5.8
-10.8
chorismate pyruvate-lyase family protein
compare
MMP
_RS04500
-5.8
-17.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS01175
-5.8
-5.5
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS03315
-5.8
-2.2
ferrous iron transport protein A
compare
MMP
_RS06895
-5.6
-2.8
selenocysteine-specific translation elongation factor
compare
MMP
_RS01005
-5.6
-1.7
riboflavin synthase
compare
MMP
_RS07730
-5.6
-2.7
pyruvate synthase subunit beta
compare
MMP
_RS01225
-5.5
-7.0
DUF5379 domain-containing protein
compare
MMP
_RS00300
-5.5
-1.2
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS03700
-5.4
-14.4
sodium:proton antiporter
compare
MMP
_RS01380
-5.4
-5.6
PHP domain-containing protein
compare
MMP
_RS08435
-5.4
-3.8
Era-like GTP-binding protein
compare
MMP
_RS08715
-5.4
-3.2
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS00110
-5.4
-4.8
hypothetical protein
compare
MMP
_RS03600
-5.3
-3.6
triose-phosphate isomerase
compare
MMP
_RS00305
-5.3
-3.6
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS08720
-5.3
-2.3
4Fe-4S binding protein
compare
MMP
_RS02240
-5.3
-4.8
methanogenesis marker 7 protein
compare
MMP
_RS07755
-5.2
-1.6
DUF555 domain-containing protein
compare
MMP
_RS08635
-5.2
-2.8
UbiA family prenyltransferase
compare
MMP
_RS01745
-5.1
-7.7
AMP phosphorylase
compare
MMP
_RS06670
-5.1
-8.4
glucose-6-phosphate isomerase
compare
MMP
_RS07750
-5.1
-6.5
DUF357 domain-containing protein
compare
MMP
_RS08210
-5.1
-3.7
phosphatidylglycerophosphatase A
compare
MMP
_RS08790
-5.0
-3.6
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS04775
-5.0
-5.1
adenosylhomocysteinase
compare
MMP
_RS01830
-5.0
-2.2
tRNA-Val
compare
MMP
_RS07005
-5.0
-1.1
4Fe-4S binding protein
compare
MMP
_RS08100
-4.9
-9.1
8-amino-7-oxononanoate synthase
compare
MMP
_RS00895
-4.9
-6.4
hypothetical protein
compare
MMP
_RS02195
-4.8
-5.6
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS06630
-4.8
-1.5
UPF0058 family protein
compare
MMP
_RS02345
-4.8
-5.7
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS08095
-4.8
-8.0
dethiobiotin synthase
compare
MMP
_RS00515
-4.8
-1.5
DUF655 domain-containing protein
compare
MMP
_RS01955
-4.7
-3.7
hypothetical protein
compare
MMP
_RS01800
-4.7
-7.2
TIGR00303 family protein
compare
MMP
_RS00325
-4.7
-2.5
RNA-binding protein
compare
MMP
_RS05250
-4.6
-3.1
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS01220
-4.6
-10.2
hypothetical protein
compare
MMP
_RS05290
-4.6
-9.8
TetR/AcrR family transcriptional regulator
compare
MMP
_RS01325
-4.6
-3.3
dihydroneopterin aldolase family protein
compare
MMP
_RS06270
-4.5
-8.4
TIGR00300 family protein
compare
MMP
_RS07075
-4.5
-5.9
phosphomannomutase/phosphoglucomutase
compare
MMP
_RS06315
-4.5
-1.4
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS03435
-4.5
-3.0
ketol-acid reductoisomerase
compare
MMP
_RS02010
-4.5
-12.2
PHP domain-containing protein
compare
MMP
_RS08105
-4.5
-8.5
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS07645
-4.4
-8.0
aldehyde dehydrogenase family protein
compare
MMP
_RS07195
-4.4
-11.2
M20 family metallo-hydrolase
compare
MMP
_RS02135
-4.4
-6.1
DUF5612 domain-containing protein
compare
MMP
_RS07390
-4.4
-4.0
cell division protein FtsZ
compare
MMP
_RS01700
-4.4
-1.4
dihydroxy-acid dehydratase
compare
MMP
_RS06295
-4.4
-9.4
methanogenesis marker 14 protein
compare
MMP
_RS06230
-4.3
-3.8
helix-turn-helix domain-containing protein
compare
MMP
_RS06370
-4.3
-5.3
biotin synthase BioB
compare
MMP
_RS01725
-4.3
-6.7
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS03155
-4.3
-8.7
precorrin-6A reductase
compare
MMP
_RS00685
-4.3
-6.5
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS04685
-4.2
-5.2
DUF126 domain-containing protein
compare
MMP
_RS01020
-4.2
-1.6
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS01335
-4.1
-3.6
prefoldin subunit beta
compare
MMP
_RS05640
-4.1
-8.4
UTP--glucose-1-phosphate uridylyltransferase GalU
compare
MMP
_RS08745
-4.1
-8.3
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS07635
-4.1
-7.9
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS07545
-4.1
-1.3
HTH domain-containing protein
compare
MMP
_RS03035
-4.1
-5.3
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS05440
-4.1
-10.3
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS00040
-4.0
-6.0
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS04780
-4.0
-4.7
ribonuclease P
compare
MMP
_RS02280
-4.0
-1.2
DUF211 domain-containing protein
compare
MMP
_RS02355
-4.0
-4.8
30S ribosomal protein S27ae
compare
MMP
_RS08440
-4.0
-5.2
cell division protein SepF
compare
MMP
_RS06020
-4.0
-6.4
archaeoflavoprotein AfpA
compare
MMP
_RS06475
-4.0
-6.5
FAD-dependent oxidoreductase
compare
MMP
_RS06885
-3.9
-2.7
50S ribosome-binding GTPase
compare
MMP
_RS07200
-3.9
-10.7
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS05815
-3.9
-3.3
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS06340
-3.9
-11.6
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS06925
-3.8
-4.1
ribonuclease VapC4
compare
MMP
_RS03640
-3.8
-6.1
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS07605
-3.8
-4.8
diadenylate cyclase
compare
MMP
_RS06625
-3.8
-3.6
DNA primase
compare
MMP
_RS05555
-3.7
-2.0
DUF4040 domain-containing protein
compare
MMP
_RS05930
-3.7
-3.8
3-isopropylmalate dehydratase large subunit
compare
MMP
_RS00810
-3.6
-12.9
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS05920
-3.6
-1.1
50S ribosomal protein L37e
compare
MMP
_RS05845
-3.6
-2.9
tRNA-intron lyase
compare
MMP
_RS00450
-3.5
-3.3
4Fe-4S binding protein
compare
MMP
_RS02190
-3.5
-5.1
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS05265
-3.5
-3.8
2-isopropylmalate synthase
compare
MMP
_RS03475
-3.5
-1.1
hypothetical protein
compare
MMP
_RS01755
-3.5
-2.0
DUF2097 domain-containing protein
compare
MMP
_RS03445
-3.5
-1.7
methanogenesis marker 17 protein
compare
MMP
_RS07580
-3.5
-3.2
DUF356 domain-containing protein
compare
MMP
_RS01900
-3.4
-18.6
hypothetical protein
compare
MMP
_RS06980
-3.4
-10.1
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS02145
-3.4
-7.2
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS00750
-3.4
-3.4
fumarate hydratase
compare
MMP
_RS07735
-3.4
-1.0
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS02900
-3.4
-1.0
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS06110
-3.4
-4.5
ATP-dependent protease LonB
compare
MMP
_RS03960
-3.4
-1.6
hypothetical protein
compare
MMP
_RS01910
-3.3
-10.5
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMP
_RS06105
-3.3
-13.8
hydrogenase maturation peptidase HycI
compare
MMP
_RS08300
-3.3
-2.1
metal-sulfur cluster assembly factor
compare
MMP
_RS01905
-3.3
-15.8
glycosyltransferase
compare
MMP
_RS00050
-3.3
-11.8
AarF/UbiB family protein
compare
MMP
_RS01925
-3.2
-9.6
DUF1616 domain-containing protein
compare
MMP
_RS05425
-3.2
-6.9
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS07380
-3.2
-3.3
transcription elongation factor Spt5
compare
MMP
_RS01610
-3.1
-4.3
hypothetical protein
compare
MMP
_RS01365
-3.1
-4.3
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS01915
-3.1
-13.2
DUF354 domain-containing protein
compare
MMP
_RS01795
-3.0
-2.3
methanogenesis marker 6 protein
compare
MMP
_RS03140
-3.0
-16.0
hypothetical protein
compare
MMP
_RS08650
-3.0
-4.9
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS04890
-3.0
-1.3
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS03145
-3.0
-11.3
fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
compare
MMP
_RS02800
-3.0
-6.1
nucleotidyltransferase domain-containing protein
compare
MMP
_RS06840
-3.0
-1.3
DNA-directed RNA polymerase subunit N
compare
MMP
_RS01385
-2.9
-1.1
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS00115
-2.9
-12.7
radical SAM protein
compare
MMP
_RS06215
-2.9
-3.4
30S ribosomal protein S6e
compare
MMP
_RS01575
-2.9
-7.8
aldolase
compare
MMP
_RS00985
-2.9
-7.8
CDC48 family AAA ATPase
compare
MMP
_RS01920
-2.8
-13.0
glycosyltransferase family 2 protein
compare
MMP
_RS00320
-2.8
-3.3
class I SAM-dependent methyltransferase
compare
MMP
_RS05525
-2.8
-9.2
calcium/sodium antiporter
compare
MMP
_RS00695
-2.7
-1.4
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS02245
-2.7
-5.9
hypothetical protein
compare
MMP
_RS07630
-2.7
-2.2
ATP-binding cassette domain-containing protein
compare
MMP
_RS07435
-2.6
-3.1
GMP synthase subunit A
compare
MMP
_RS06725
-2.6
-13.2
hypothetical protein
compare
MMP
_RS03580
-2.6
-4.2
signal recognition particle-docking protein FtsY
compare
MMP
_RS04605
-2.6
-4.7
cobalt ECF transporter T component CbiQ
compare
MMP
_RS06940
-2.6
-3.4
polyprenyl diphosphate synthase
compare
MMP
_RS04850
-2.6
-19.2
UPF0254 family protein
compare
MMP
_RS03095
-2.5
-9.1
diphthine synthase
compare
MMP
_RS07695
-2.5
-7.9
DUF3236 domain-containing protein
compare
MMP
_RS00720
-2.5
-10.1
metal-dependent hydrolase
compare
MMP
_RS01970
-2.5
-9.9
TIGR04279 domain-containing protein
compare
MMP
_RS01895
-2.5
-11.1
flippase
compare
MMP
_RS02290
-2.5
-11.1
MBL fold metallo-hydrolase
compare
MMP
_RS00315
-2.5
-10.8
Nif3-like dinuclear metal center hexameric protein
compare
MMP
_RS06310
-2.4
-4.0
NAD(P)/FAD-dependent oxidoreductase
compare
MMP
_RS04900
-2.4
-18.9
hypothetical protein
compare
MMP
_RS03270
-2.4
-11.7
ADP-ribosylglycohydrolase family protein
compare
MMP
_RS00520
-2.4
-2.7
RNA polymerase Rpb4 family protein
compare
MMP
_RS05345
-2.4
-8.7
hypothetical protein
compare
MMP
_RS06175
-2.4
-8.7
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS05925
-2.3
-4.2
small nuclear ribonucleoprotein
compare
MMP
_RS00725
-2.3
-9.9
5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
compare
MMP
_RS02235
-2.3
-11.4
CBS domain-containing protein
compare
MMP
_RS07420
-2.3
-3.6
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS06395
-2.3
-5.5
ThiF family adenylyltransferase
compare
MMP
_RS04615
-2.2
-3.2
PDGLE domain-containing protein
compare
MMP
_RS03110
-2.2
-7.0
glycosyltransferase family 2 protein
compare
MMP
_RS05500
-2.2
-8.7
2-isopropylmalate synthase
compare
MMP
_RS01415
-2.2
-5.2
DUF2067 domain-containing protein
compare
MMP
_RS07355
-2.2
-1.3
transcription factor S
compare
MMP
_RS07425
-2.1
-6.1
GTP-binding protein
compare
MMP
_RS06865
-2.1
-2.2
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS07525
-2.1
-9.7
4Fe-4S binding protein
compare
MMP
_RS07350
-2.1
-1.6
preprotein translocase subunit Sec61beta
compare
MMP
_RS08330
-2.1
-4.0
NADH-quinone oxidoreductase subunit H
compare
MMP
_RS07555
-2.1
-1.0
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS04870
-2.1
-4.5
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS01265
-2.1
-2.3
hypothetical protein
compare
MMP
_RS01885
-2.1
-7.3
Gfo/Idh/MocA family oxidoreductase
compare
MMP
_RS08445
-2.1
-5.4
DUF2099 family protein
compare
MMP
_RS08785
-2.1
-1.8
RNA-protein complex protein Nop10
compare
MMP
_RS00900
-2.1
-3.5
50S ribosomal protein L39e
compare
MMP
_RS00735
-2.0
-4.3
5 10-methenyltetrahydromethanopterin hydrogenase
compare
MMP
_RS07090
-2.0
-9.6
tRNA (adenine-N1)-methyltransferase
compare
MMP
_RS05445
-2.0
-8.1
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS05875
-2.0
-7.1
hydroxyethylthiazole kinase
compare
MMP
_RS00130
-2.0
-1.7
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS01975
-2.0
-13.1
hypothetical protein
compare
Specific Phenotypes
For 3 genes in this experiment