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Experiment set3IT022 for
Methanococcus maripaludis S2
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H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS08860
+1.7
8.7
MinD/ParA family protein
compare
MMP
_RS08855
+1.7
13.6
hypothetical protein
compare
MMP
_RS01290
+1.6
14.4
class III signal peptide-containing protein
compare
MMP
_RS01280
+1.6
13.8
DUF515 domain-containing protein
compare
MMP
_RS01305
+1.5
14.2
hypothetical protein
compare
MMP
_RS00240
+1.5
13.7
type II secretion system F family protein
compare
MMP
_RS00245
+1.5
13.9
type II secretion system F family protein
compare
MMP
_RS08675
+1.5
6.4
class III signal peptide-containing protein
compare
MMP
_RS01285
+1.5
13.2
hypothetical protein
compare
MMP
_RS00250
+1.5
13.4
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS01310
+1.5
12.8
hypothetical protein
compare
MMP
_RS01315
+1.4
13.7
DUF2341 domain-containing protein
compare
MMP
_RS01270
+1.4
12.7
prepilin peptidase
compare
MMP
_RS01295
+1.4
11.4
hypothetical protein
compare
MMP
_RS08615
+1.3
2.6
flagellar protein G
compare
MMP
_RS01275
+1.3
8.8
class III signal peptide-containing protein
compare
MMP
_RS03125
+1.3
8.1
cell division ATPase MinD
compare
MMP
_RS06720
+1.2
5.5
response regulator transcription factor
compare
MMP
_RS01085
+1.2
3.6
hypothetical protein
compare
MMP
_RS08940
+1.2
2.6
MetS family NSS transporter small subunit
compare
MMP
_RS09055
+1.2
2.0
CAP domain-containing protein
compare
MMP
_RS06715
+1.2
9.5
cache domain-containing protein
compare
MMP
_RS05985
+1.0
2.9
hypothetical protein
compare
MMP
_RS01195
+1.0
2.0
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS05635
+1.0
6.9
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS08580
+1.0
6.9
flagellin
compare
MMP
_RS08845
+0.9
5.3
archaellum operon transcriptional activator EarA family protein
compare
MMP
_RS08750
+0.8
1.6
hypothetical protein
compare
MMP
_RS00140
+0.8
5.1
DUF192 domain-containing protein
compare
MMP
_RS00345
+0.8
4.3
DUF2666 domain-containing protein
compare
MMP
_RS09045
+0.8
5.3
class III signal peptide-containing protein
compare
MMP
_RS08400
+0.7
1.9
MJ0307 family thioredoxin
compare
MMP
_RS08850
+0.7
6.4
hypothetical protein
compare
MMP
_RS05865
+0.7
1.1
hypothetical protein
compare
MMP
_RS06600
+0.7
0.5
class III signal peptide-containing protein
compare
MMP
_RS05580
+0.7
6.1
glycosyltransferase
compare
MMP
_RS07900
+0.7
1.5
YeeE/YedE family protein
compare
MMP
_RS06035
+0.7
3.1
glycosyltransferase family 2 protein
compare
MMP
_RS04410
+0.6
2.2
hypothetical protein
compare
MMP
_RS02545
+0.6
2.2
hypothetical protein
compare
MMP
_RS08410
+0.6
2.2
DUF169 domain-containing protein
compare
MMP
_RS01790
+0.6
2.2
restriction endonuclease
compare
MMP
_RS00570
+0.6
0.8
protein-L-isoaspartate O-methyltransferase
compare
MMP
_RS03340
+0.6
0.7
ABC transporter ATP-binding protein
compare
MMP
_RS08830
+0.6
3.3
GTP-binding protein
compare
MMP
_RS07345
+0.6
2.6
glycine synthesis protein GlyXL
(from data)
compare
MMP
_RS00535
+0.6
1.7
TIGR00375 family protein
compare
MMP
_RS07330
+0.6
5.2
membrane protein
compare
MMP
_RS08310
+0.6
1.6
TMEM165/GDT1 family protein
compare
MMP
_RS08395
+0.6
2.3
DsrE family protein
compare
MMP
_RS02295
+0.6
4.5
TatD family hydrolase
compare
MMP
_RS03625
+0.6
2.7
cell wall-binding protein
compare
MMP
_RS03535
+0.5
1.3
helix-turn-helix transcriptional regulator
compare
MMP
_RS04125
+0.5
1.9
TetR/AcrR family transcriptional regulator
compare
MMP
_RS08290
+0.5
3.3
DNA-binding protein Alba
compare
MMP
_RS08285
+0.5
2.6
serine/threonine protein kinase
compare
MMP
_RS00710
+0.5
2.4
hypothetical protein
compare
MMP
_RS05785
+0.5
3.8
ATP-binding protein
compare
MMP
_RS01075
+0.5
0.7
hypothetical protein
compare
MMP
_RS01255
+0.5
1.7
amino acid ABC transporter ATP-binding protein
compare
MMP
_RS08700
+0.5
3.7
hypothetical protein
compare
MMP
_RS08280
+0.5
1.6
proteasome assembly chaperone family protein
compare
MMP
_RS05975
+0.5
1.0
hypothetical protein
compare
MMP
_RS03965
+0.5
1.5
hypothetical protein
compare
MMP
_RS08610
+0.5
3.1
flagellar protein F
compare
MMP
_RS01655
+0.5
1.3
DsrE family protein
compare
MMP
_RS08980
+0.5
1.9
hypothetical protein
compare
MMP
_RS01570
+0.4
0.9
hypothetical protein
compare
MMP
_RS06935
+0.4
2.0
protease complex subunit PrcB family protein
compare
MMP
_RS01630
+0.4
3.1
N-glycosylase/DNA lyase
compare
MMP
_RS01660
+0.4
1.5
hypothetical protein
compare
MMP
_RS00655
+0.4
1.8
hypothetical protein
compare
MMP
_RS01125
+0.4
1.9
thioredoxin family protein
compare
MMP
_RS08775
+0.4
2.5
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS02530
+0.4
1.6
type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family
compare
MMP
_RS05965
+0.4
1.0
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS08665
+0.4
3.6
hypothetical protein
compare
MMP
_RS01110
+0.4
0.9
FmdE family protein
compare
MMP
_RS07985
+0.4
3.1
nitroreductase family protein
compare
MMP
_RS07550
+0.4
2.2
L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
compare
MMP
_RS01870
+0.4
1.7
acyl-CoA dehydratase activase
compare
MMP
_RS07800
+0.4
1.7
ATP-binding cassette domain-containing protein
compare
MMP
_RS08265
+0.4
2.1
rubrerythrin
compare
MMP
_RS01135
+0.4
2.5
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS01300
+0.4
3.3
hypothetical protein
compare
MMP
_RS07640
+0.4
1.8
mechanosensitive ion channel family protein
compare
MMP
_RS02425
+0.4
1.8
hypothetical protein
compare
MMP
_RS02260
+0.4
2.3
lactate utilization protein
compare
MMP
_RS07775
+0.4
1.1
alanine dehydrogenase
compare
MMP
_RS08475
+0.4
1.7
ABC transporter permease
compare
MMP
_RS00690
+0.4
1.6
MBL fold metallo-hydrolase
compare
MMP
_RS08640
+0.4
2.9
TIM barrel protein
compare
MMP
_RS08160
+0.4
2.2
EamA family transporter
compare
MMP
_RS08205
+0.4
2.5
stage II sporulation protein M
compare
MMP
_RS09025
+0.4
0.6
hypothetical protein
compare
MMP
_RS08485
+0.4
2.0
tungstate ABC transporter substrate-binding protein WtpA
compare
MMP
_RS02255
+0.4
1.7
hypothetical protein
compare
MMP
_RS03550
+0.3
0.7
DUF2124 domain-containing protein
compare
MMP
_RS03120
+0.3
1.0
hypothetical protein
compare
MMP
_RS02370
+0.3
1.8
NifB/NifX family molybdenum-iron cluster-binding protein
compare
MMP
_RS06050
+0.3
2.2
ZIP family metal transporter
compare
MMP
_RS02540
+0.3
1.4
DUF2283 domain-containing protein
compare
MMP
_RS00540
+0.3
1.9
PLP-dependent aminotransferase family protein
compare
MMP
_RS00480
+0.3
1.3
hypothetical protein
compare
MMP
_RS08080
+0.3
1.6
YchF/TatD family DNA exonuclease
compare
MMP
_RS08770
+0.3
1.7
hypothetical protein
compare
MMP
_RS05365
+0.3
1.2
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
compare
MMP
_RS03220
+0.3
1.2
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS04610
+0.3
1.3
Dabb family protein
compare
MMP
_RS03520
+0.3
0.7
YwbE family protein
compare
MMP
_RS01490
+0.3
1.6
tetratricopeptide repeat protein
compare
MMP
_RS02730
+0.3
1.8
ModD protein
compare
MMP
_RS00660
+0.3
2.0
alkaline phosphatase family protein
compare
MMP
_RS00675
+0.3
0.3
nitroreductase family protein
compare
MMP
_RS08250
+0.3
1.7
pyruvate kinase
compare
MMP
_RS07915
+0.3
1.7
DUF4870 domain-containing protein
compare
MMP
_RS02735
+0.3
1.7
MBL fold metallo-hydrolase
compare
MMP
_RS08405
+0.3
2.0
MFS transporter
compare
MMP
_RS03845
+0.3
1.5
DNA adenine methylase
compare
MMP
_RS08480
+0.3
2.3
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS02020
+0.3
1.1
gamma-glutamylcyclotransferase
compare
MMP
_RS08620
+0.3
1.8
flagellar accessory protein FlaH
compare
MMP
_RS08235
+0.3
1.8
hypothetical protein
compare
MMP
_RS08835
+0.3
1.4
H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
compare
MMP
_RS08385
+0.3
1.1
ABC transporter substrate-binding protein
compare
MMP
_RS03060
+0.3
1.5
MBL fold metallo-hydrolase
compare
MMP
_RS08260
+0.3
1.8
DUF99 family protein
compare
MMP
_RS08490
+0.3
2.2
hypothetical protein
compare
MMP
_RS02700
+0.3
1.4
formylmethanofuran dehydrogenase subunit C
compare
MMP
_RS07910
+0.3
1.7
NAD(P)H-hydrate dehydratase
compare
MMP
_RS01185
+0.3
1.7
hypothetical protein
compare
MMP
_RS00865
+0.3
1.3
SLC13 family permease
compare
MMP
_RS00965
+0.3
0.7
hypothetical protein
compare
MMP
_RS01150
+0.3
1.8
aldo/keto reductase
compare
MMP
_RS02805
+0.3
0.5
HEPN domain-containing protein
compare
MMP
_RS06250
+0.3
1.6
hypothetical protein
compare
MMP
_RS06905
+0.3
0.9
hypothetical protein
compare
MMP
_RS01635
+0.3
1.1
thiamine pyrophosphate-dependent enzyme
compare
MMP
_RS06965
+0.3
1.5
TIGR04014 family B12-binding domain/radical SAM domain-containing protein
compare
MMP
_RS04595
+0.3
1.2
hypothetical protein
compare
MMP
_RS06560
+0.3
1.6
hypothetical protein
compare
MMP
_RS02625
+0.3
1.4
ribonuclease H-like domain-containing protein
compare
MMP
_RS08930
+0.3
0.7
hypothetical protein
compare
MMP
_RS08130
+0.3
2.1
IGHMBP2 family helicase
compare
MMP
_RS07715
+0.3
2.0
YfcE family phosphodiesterase
compare
MMP
_RS07805
+0.3
1.4
ABC transporter permease
compare
MMP
_RS02455
+0.3
1.4
hypothetical protein
compare
MMP
_RS06115
+0.3
1.6
class II aldolase/adducin family protein
compare
MMP
_RS04255
+0.3
1.1
coenzyme F420 hydrogenase subunit beta
compare
MMP
_RS04060
+0.3
1.1
hypothetical protein
compare
MMP
_RS00640
+0.3
1.1
ABC transporter substrate-binding protein
compare
MMP
_RS03530
+0.3
1.7
tetratricopeptide repeat protein
compare
MMP
_RS01090
+0.3
1.4
ABC transporter substrate-binding protein
compare
MMP
_RS07590
+0.2
1.9
hypothetical protein
compare
MMP
_RS05095
+0.2
1.2
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS08380
+0.2
1.3
phosphatase PAP2 family protein
compare
MMP
_RS04030
+0.2
1.0
hypothetical protein
compare
MMP
_RS06930
+0.2
1.8
MBL fold metallo-hydrolase
compare
MMP
_RS02850
+0.2
1.5
hypothetical protein
compare
MMP
_RS07155
+0.2
1.4
MFS transporter
compare
MMP
_RS07765
+0.2
1.3
sodium:alanine symporter family protein
compare
MMP
_RS06910
+0.2
1.4
RlmF-related methyltransferase
compare
MMP
_RS01260
+0.2
1.2
HDIG domain-containing protein
compare
MMP
_RS02790
+0.2
0.4
class III signal peptide-containing protein
compare
MMP
_RS04600
+0.2
2.0
tetratricopeptide repeat protein
compare
MMP
_RS08245
+0.2
1.2
DUF4013 domain-containing protein
compare
MMP
_RS04995
+0.2
1.5
hypothetical protein
compare
MMP
_RS00390
+0.2
1.3
ammonium transporter
compare
MMP
_RS04290
+0.2
0.9
4Fe-4S binding protein
compare
MMP
_RS05355
+0.2
0.3
hypothetical protein
compare
MMP
_RS03000
+0.2
1.6
cupin domain-containing protein
compare
MMP
_RS03755
+0.2
1.5
MarR family transcriptional regulator
compare
MMP
_RS09060
+0.2
1.8
hypothetical protein
compare
MMP
_RS01675
+0.2
0.5
hypothetical protein
compare
MMP
_RS02575
+0.2
1.4
CAAX prenyl protease Rce1
compare
MMP
_RS00435
+0.2
1.7
CPBP family intramembrane metalloprotease
compare
MMP
_RS05780
+0.2
1.3
multidrug resistance efflux transporter family protein
compare
MMP
_RS02630
+0.2
1.3
rubredoxin
compare
MMP
_RS02215
+0.2
1.3
ECF transporter S component
compare
MMP
_RS02225
+0.2
1.1
carbohydrate kinase family protein
compare
MMP
_RS06990
+0.2
1.3
CatB-related O-acetyltransferase
compare
MMP
_RS02695
+0.2
1.2
formylmethanofuran dehydrogenase subunit A
compare
MMP
_RS02385
+0.2
1.2
ATP-binding protein
compare
MMP
_RS00905
+0.2
1.0
phenylacetate--CoA ligase
compare
MMP
_RS00395
+0.2
0.5
MGMT family protein
compare
MMP
_RS07100
+0.2
1.4
hypothetical protein
compare
MMP
_RS01690
+0.2
1.4
indolepyruvate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS01440
+0.2
0.8
NAAT family transporter
compare
MMP
_RS03900
+0.2
1.1
minichromosome maintenance protein MCM
compare
MMP
_RS09065
+0.2
1.6
hypothetical protein
compare
MMP
_RS03230
+0.2
1.2
flavodoxin family protein
compare
MMP
_RS01070
+0.2
1.5
hypothetical protein
compare
MMP
_RS01980
+0.2
1.7
trimeric intracellular cation channel family protein
compare
MMP
_RS02825
+0.2
1.3
mechanosensitive ion channel family protein
compare
MMP
_RS02610
+0.2
0.6
DUF2162 domain-containing protein
compare
MMP
_RS06710
+0.2
1.0
selenium-binding protein
compare
MMP
_RS02670
+0.2
1.3
ATP-binding cassette domain-containing protein
compare
MMP
_RS00085
+0.2
1.6
DNA cytosine methyltransferase
compare
MMP
_RS06305
+0.2
1.5
transporter substrate-binding domain-containing protein
compare
MMP
_RS00235
+0.2
1.1
HDIG domain-containing protein
compare
Specific Phenotypes
For 3 genes in this experiment