Experiment set3IT019 for Cupriavidus basilensis FW507-4G11

Compare to:

L-Tryptophan nitrogen source

200 most important genes:

  gene name fitness t score description  
RR42_RS01385 -7.3 -5.0 5,10-methylenetetrahydrofolate reductase compare
RR42_RS05860 -6.9 -4.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
RR42_RS19005 -6.4 -4.4 3-dehydroquinate synthase compare
RR42_RS16265 -6.2 -5.0 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
RR42_RS16255 -6.1 -7.2 sulfate adenylyltransferase compare
RR42_RS14390 -6.0 -4.1 3-isopropylmalate dehydratase compare
RR42_RS16250 -5.8 -5.7 sulfate adenylyltransferase compare
RR42_RS30655 -5.8 -5.6 LysR family transcriptional regulator compare
RR42_RS06485 -5.6 -7.7 chorismate synthase compare
RR42_RS14400 -5.6 -3.9 isopropylmalate isomerase compare
RR42_RS14385 -5.6 -5.4 3-isopropylmalate dehydrogenase compare
RR42_RS04535 -5.4 -3.7 cysteine synthase compare
RR42_RS33255 -5.4 -3.4 protein-tyrosine phosphatase compare
RR42_RS16275 -5.1 -3.5 membrane protein compare
RR42_RS21220 -4.9 -3.4 iron transporter FeoB compare
RR42_RS30660 -4.9 -10.4 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase compare
RR42_RS11795 -4.7 -2.6 PEP synthetase regulatory protein compare
RR42_RS16270 -4.7 -10.8 sulfite reductase compare
RR42_RS01160 -4.6 -9.6 homoserine O-acetyltransferase compare
RR42_RS16245 -4.6 -6.2 uroporphyrin-III methyltransferase compare
RR42_RS15890 -4.3 -9.1 heme biosynthesis protein HemY compare
RR42_RS33260 -4.3 -9.1 multidrug MFS transporter compare
RR42_RS14320 -4.3 -6.0 O-succinylhomoserine sulfhydrylase compare
RR42_RS15385 -4.3 -12.8 Kynureninase (EC 3.7.1.3) (from data) conserved
RR42_RS04475 -4.3 -7.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
RR42_RS15905 -4.2 -11.5 phosphoenolpyruvate carboxylase compare
RR42_RS12040 -4.1 -11.8 MFS transporter compare
RR42_RS07605 -4.0 -6.7 poly-beta-hydroxybutyrate polymerase compare
RR42_RS17645 -4.0 -6.1 shikimate dehydrogenase compare
RR42_RS11885 -3.9 -10.7 (protein-PII) uridylyltransferase compare
RR42_RS19010 -3.8 -10.0 shikimate kinase compare
RR42_RS33250 -3.8 -7.6 tyrosine protein kinase compare
RR42_RS18990 -3.8 -17.5 glutamate synthase compare
RR42_RS33210 -3.8 -7.1 teichoic acid biosynthesis protein compare
RR42_RS01845 -3.8 -2.4 glycerol-3-phosphate dehydrogenase compare
RR42_RS33240 -3.8 -15.7 GDP-L-fucose synthase compare
RR42_RS37400 -3.7 -1.6 6-phosphogluconolactonase compare
RR42_RS16280 -3.6 -5.6 transcriptional regulator compare
RR42_RS12980 -3.6 -6.1 chemotaxis protein CheY compare
RR42_RS15375 -3.6 -5.4 AsnC family transcriptional regulator conserved
RR42_RS01290 -3.6 -6.8 thiamine biosynthesis protein ThiC compare
RR42_RS16960 -3.6 -9.7 ABC transporter ATP-binding protein compare
RR42_RS17105 -3.5 -11.9 Clp protease ClpX compare
RR42_RS11790 -3.5 -7.2 phosphoenolpyruvate synthase compare
RR42_RS15390 -3.4 -7.1 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (from data) conserved
RR42_RS13800 -3.3 -7.7 formyltetrahydrofolate deformylase compare
RR42_RS33245 -3.3 -9.9 mannose-1-phosphate guanyltransferase compare
RR42_RS18985 -3.3 -7.1 glutamate synthase compare
RR42_RS16965 -3.1 -7.1 ABC transporter compare
RR42_RS15895 -3.1 -5.6 uroporphyrinogen III methyltransferase compare
RR42_RS33235 -3.0 -8.5 GDP-mannose 4,6-dehydratase compare
RR42_RS03080 -3.0 -3.7 recombinase RecA compare
RR42_RS16980 -3.0 -13.1 branched-chain amino acid ABC transporter substrate-binding protein compare
RR42_RS16975 -3.0 -8.2 ABC transporter permease compare
RR42_RS15380 -2.8 -3.8 kynurenine formamidase compare
RR42_RS04460 -2.8 -4.6 chorismate mutase compare
RR42_RS12985 -2.6 -5.4 histidine kinase compare
RR42_RS16970 -2.5 -10.3 ABC transporter ATP-binding protein compare
RR42_RS02705 -2.5 -3.3 Holliday junction DNA helicase RuvA compare
RR42_RS01775 -2.5 -5.9 glutamate--cysteine ligase compare
RR42_RS18855 -2.5 -5.0 preprotein translocase compare
RR42_RS14790 -2.5 -7.3 cobalamin biosynthesis protein CobD compare
RR42_RS16240 -2.4 -1.3 cobalamin biosynthesis protein CbiX compare
RR42_RS00115 -2.4 -3.2 hypothetical protein compare
RR42_RS02085 -2.3 -7.7 RNA polymerase subunit sigma-54 compare
RR42_RS08575 -2.3 -1.9 tail protein compare
RR42_RS14055 -2.2 -3.9 elongation factor 4 compare
RR42_RS13550 -2.2 -4.9 3-hydroxyacyl-CoA dehydrogenase conserved
RR42_RS13540 -2.2 -4.8 acyl-CoA dehydrogenase compare
RR42_RS21690 -2.2 -1.3 acetyltransferase compare
RR42_RS13620 -2.2 -1.8 ferredoxin compare
RR42_RS33355 -2.2 -3.7 membrane protein compare
RR42_RS04700 -2.2 -1.8 ribonuclease G compare
RR42_RS24605 -2.1 -7.3 TetR family transcriptional regulator compare
RR42_RS04895 -2.1 -12.1 serine/threonine protein phosphatase compare
RR42_RS15640 -2.1 -2.0 hypothetical protein compare
RR42_RS02320 -2.1 -5.3 trehalose phosphatase compare
RR42_RS13530 -2.1 -3.1 4-hydroxybenzoyl-CoA thioesterase compare
RR42_RS12925 -2.1 -3.0 ATPase compare
RR42_RS13555 -2.0 -6.8 anthraniloyl-CoA monooxygenase (EC 1.14.13.40) (from data) compare
RR42_RS04585 -2.0 -8.1 amino acid dehydrogenase compare
RR42_RS01780 -2.0 -7.5 glutathione synthetase compare
RR42_RS15400 -2.0 -6.8 acyl-CoA dehydrogenase compare
RR42_RS18850 -2.0 -3.2 preprotein translocase subunit TatC compare
RR42_RS17720 -2.0 -3.1 sugar kinase compare
RR42_RS19885 -1.9 -1.9 aminoglycoside transporter compare
RR42_RS16220 -1.9 -1.6 DNA polymerase III subunit chi compare
RR42_RS15845 -1.9 -2.6 biotin transporter BioY compare
RR42_RS20205 -1.8 -3.3 chromosome partitioning protein compare
RR42_RS06860 -1.8 -1.4 hypothetical protein compare
RR42_RS26900 -1.7 -3.0 enoyl-CoA hydratase compare
RR42_RS01380 -1.7 -1.7 membrane protein compare
RR42_RS02775 -1.7 -2.4 molecular chaperone SurA compare
RR42_RS03095 -1.7 -2.1 succinyl-CoA synthetase subunit beta compare
RR42_RS12550 -1.7 -3.0 hypothetical protein compare
RR42_RS33215 -1.6 -8.4 transferase compare
RR42_RS14360 -1.6 -1.7 tryptophan synthase subunit alpha compare
RR42_RS19090 -1.6 -1.5 cytochrome C compare
RR42_RS07440 -1.6 -3.3 hypothetical protein compare
RR42_RS04590 -1.6 -7.7 AsnC family transcriptional regulator compare
RR42_RS05920 -1.6 -3.9 HrcA family transcriptional regulator compare
RR42_RS18430 -1.6 -2.9 prevent-host-death protein compare
RR42_RS24790 -1.6 -1.8 LysR family transcriptional regulator compare
RR42_RS03035 -1.6 -1.6 membrane protein compare
RR42_RS15410 -1.6 -4.3 membrane protein compare
RR42_RS00725 -1.6 -5.5 hypothetical protein compare
RR42_RS04015 -1.5 -1.5 RNA polymerase sigma factor compare
RR42_RS17060 -1.5 -10.3 histidine kinase compare
RR42_RS12015 -1.5 -2.3 dihydrolipoamide acyltransferase compare
RR42_RS02045 -1.5 -9.7 GTPase compare
RR42_RS19085 -1.5 -2.1 cytochrome C biogenesis protein ResB compare
RR42_RS23110 -1.5 -1.9 isochorismatase compare
RR42_RS18825 -1.4 -4.1 ubiquinol-cytochrome C reductase compare
RR42_RS07555 -1.4 -1.8 potassium transporter Kup compare
RR42_RS02500 -1.4 -1.5 TetR family transcriptional regulator compare
RR42_RS17390 -1.4 -4.5 ATP-dependent DNA helicase RecG compare
RR42_RS08180 -1.4 -1.5 hypothetical protein compare
RR42_RS24490 -1.4 -1.9 hypothetical protein compare
RR42_RS16335 -1.4 -2.3 hypothetical protein compare
RR42_RS26935 -1.3 -4.4 farnesyl-diphosphate farnesyltransferase compare
RR42_RS05990 -1.3 -5.8 aromatic amino acid aminotransferase compare
RR42_RS02860 -1.3 -2.6 hypothetical protein compare
RR42_RS21435 -1.3 -3.1 hypothetical protein compare
RR42_RS04770 -1.3 -1.5 methylglyoxal synthase compare
RR42_RS00440 -1.3 -1.5 hypothetical protein compare
RR42_RS25510 -1.3 -2.4 short-chain dehydrogenase compare
RR42_RS32590 -1.3 -1.7 cytochrome o ubiquinol oxidase subunit III compare
RR42_RS16460 -1.2 -3.3 cupin compare
RR42_RS01920 -1.2 -2.0 protoheme IX farnesyltransferase compare
RR42_RS17055 -1.2 -5.4 LuxR family transcriptional regulator compare
RR42_RS01880 -1.2 -4.4 cytochrome oxidase subunit I compare
RR42_RS21695 -1.2 -4.3 DNA-binding protein compare
RR42_RS01885 -1.2 -4.5 cytochrome C oxidase assembly protein compare
RR42_RS06430 -1.2 -2.7 hypothetical protein compare
RR42_RS00790 -1.2 -4.6 chemotaxis protein CheY compare
RR42_RS33575 -1.2 -1.9 hypothetical protein compare
RR42_RS20195 -1.2 -1.2 ATPase F0F1 compare
RR42_RS15740 -1.2 -1.7 hypothetical protein compare
RR42_RS35875 -1.2 -6.5 UDP-galactose-4-epimerase compare
RR42_RS13040 -1.2 -3.3 iron transporter compare
RR42_RS13535 -1.2 -8.0 2-aminobenzoate-CoA ligase (EC 6.2.1.32) (from data) compare
RR42_RS31830 -1.2 -1.2 short-chain dehydrogenase compare
RR42_RS01905 -1.1 -3.0 cytochrome C oxidase subunit II compare
RR42_RS12050 -1.1 -5.8 DNA polymerase compare
RR42_RS13025 -1.1 -3.7 hypothetical protein compare
RR42_RS18820 -1.1 -3.8 cytochrome B compare
RR42_RS06095 -1.1 -3.8 hypothetical protein compare
RR42_RS18815 -1.1 -4.6 cytochrome C compare
RR42_RS07140 -1.1 -1.8 hypothetical protein compare
RR42_RS09760 -1.1 -2.4 hypothetical protein compare
RR42_RS26905 -1.1 -4.5 methylcrotonoyl-CoA carboxylase compare
RR42_RS06395 -1.1 -5.1 TetR family transcriptional regulator compare
RR42_RS06015 -1.1 -7.1 recombinase compare
RR42_RS33195 -1.1 -7.6 UDP-sugar lipid carrier transferase compare
RR42_RS19695 -1.1 -1.6 cytochrome C protein compare
RR42_RS13050 -1.1 -5.6 transaldolase compare
RR42_RS15785 -1.1 -5.8 glycosyl transferase family 28 compare
RR42_RS12125 -1.1 -1.8 LuxR family transcriptional regulator compare
RR42_RS15050 -1.0 -4.9 DNA polymerase I compare
RR42_RS06630 -1.0 -1.9 integration host factor subunit alpha compare
RR42_RS32495 -1.0 -2.0 shikimate kinase compare
RR42_RS28615 -1.0 -2.4 ABC transporter substrate-binding protein compare
RR42_RS11770 -1.0 -1.8 cyclase compare
RR42_RS07255 -1.0 -3.0 hypothetical protein compare
RR42_RS01820 -1.0 -3.9 peptidase S41 compare
RR42_RS14965 -1.0 -2.2 hypothetical protein compare
RR42_RS02750 -1.0 -4.4 mannose-1-phosphate guanylyltransferase compare
RR42_RS31530 -1.0 -2.6 histidine kinase compare
RR42_RS34565 -1.0 -2.2 GDP-mannose mannosyl hydrolase compare
RR42_RS34585 -1.0 -1.7 LysR family transcriptional regulator compare
RR42_RS00610 -1.0 -4.5 hypothetical protein compare
RR42_RS01910 -1.0 -3.4 cytochrome C oxidase subunit I compare
RR42_RS18485 -1.0 -0.9 glutaredoxin compare
RR42_RS36660 -1.0 -3.0 GntR family transcriptional regulator compare
RR42_RS01255 -1.0 -4.7 lauroyl acyltransferase compare
RR42_RS03680 -1.0 -2.4 hypothetical protein compare
RR42_RS01915 -1.0 -3.7 cytochrome C oxidase subunit I compare
RR42_RS22570 -1.0 -1.1 SAM-dependent methyltransferase compare
RR42_RS37170 -1.0 -1.8 MazF family transcriptional regulator compare
RR42_RS20210 -1.0 -3.2 16S rRNA methyltransferase compare
RR42_RS29235 -0.9 -3.5 hypothetical protein compare
RR42_RS09015 -0.9 -1.7 trigger factor compare
RR42_RS07565 -0.9 -4.5 transcription accessory protein compare
RR42_RS16360 -0.9 -1.9 transposase compare
RR42_RS32975 -0.9 -1.3 LysR family transcriptional regulator compare
RR42_RS15525 -0.9 -0.7 hypothetical protein compare
RR42_RS12520 -0.9 -3.5 molybdenum cofactor biosynthesis protein MoaE compare
RR42_RS17490 -0.9 -2.3 NADP transhydrogenase subunit alpha compare
RR42_RS31285 -0.9 -1.3 XRE family transcriptional regulator compare
RR42_RS30640 -0.9 -3.8 DNA mismatch repair protein MutT compare
RR42_RS29865 -0.9 -1.8 hypothetical protein compare
RR42_RS17880 -0.9 -0.9 hypothetical protein compare
RR42_RS20775 -0.9 -0.6 hypothetical protein compare
RR42_RS15810 -0.9 -2.9 UDP-N-acetylglucosamine 4,6-dehydratase compare
RR42_RS00380 -0.9 -4.1 GntR family transcriptional regulator compare
RR42_RS03940 -0.9 -1.4 membrane protein compare
RR42_RS03345 -0.9 -3.4 recombinase XerD compare
RR42_RS34525 -0.9 -2.0 type VI secretion protein VasK compare
RR42_RS06875 -0.9 -1.7 hypothetical protein compare
RR42_RS15745 -0.9 -4.4 group1 glycosyl transferase compare


Specific Phenotypes

For 5 genes in this experiment

For nitrogen source L-Tryptophan in Cupriavidus basilensis FW507-4G11

For nitrogen source L-Tryptophan across organisms