Experiment set3IT019 for Cupriavidus basilensis FW507-4G11

Compare to:

L-Tryptophan nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
RR42_RS18140 +1.7 4.0 MarR family transcriptional regulator compare
RR42_RS05085 +1.5 6.1 2-aminomuconate deaminase compare
RR42_RS24760 +1.5 2.0 hypothetical protein compare
RR42_RS18385 +1.3 3.5 hypothetical protein compare
RR42_RS32960 +1.3 3.0 2-dehydropantoate 2-reductase compare
RR42_RS16510 +1.2 2.5 hypothetical protein compare
RR42_RS05075 +1.1 3.1 aminocarboxymuconate-semialdehyde decarboxylase compare
RR42_RS35220 +1.1 2.4 peptide ABC transporter ATP-binding protein compare
RR42_RS29610 +1.1 1.8 cytochrome C2 compare
RR42_RS19860 +1.0 1.7 tartronate semialdehyde reductase compare
RR42_RS28695 +1.0 1.9 hypothetical protein compare
RR42_RS05425 +1.0 6.0 membrane protein compare
RR42_RS29280 +1.0 1.4 hypothetical protein compare
RR42_RS22180 +1.0 3.2 hypothetical protein compare
RR42_RS21755 +1.0 1.8 shikimate dehydrogenase compare
RR42_RS15000 +1.0 3.1 GTP cyclohydrolase compare
RR42_RS30735 +1.0 2.2 tRNA-Met compare
RR42_RS37045 +0.9 2.0 thiamine biosynthesis protein ApbE compare
RR42_RS08210 +0.9 1.1 hypothetical protein compare
RR42_RS13305 +0.9 1.4 hypothetical protein compare
RR42_RS22295 +0.9 1.8 methionine sulfoxide reductase B compare
RR42_RS21075 +0.9 1.1 phosphoribosyltransferase compare
RR42_RS24395 +0.9 2.4 hypothetical protein compare
RR42_RS05385 +0.9 1.9 LOG family protein compare
RR42_RS15225 +0.9 1.4 RNA-binding protein compare
RR42_RS03185 +0.9 2.9 branched-chain amino acid permease compare
RR42_RS27320 +0.8 2.0 ferredoxin compare
RR42_RS20370 +0.8 1.5 pterin-4-alpha-carbinolamine dehydratase compare
RR42_RS28400 +0.8 1.8 CoA-transferase compare
RR42_RS33175 +0.8 4.6 membrane protein compare
RR42_RS05975 +0.8 3.9 ferredoxin compare
RR42_RS35250 +0.8 1.4 alpha/beta hydrolase compare
RR42_RS24520 +0.8 3.1 hypothetical protein compare
RR42_RS07225 +0.8 1.5 hypothetical protein compare
RR42_RS34570 +0.8 1.6 hypothetical protein compare
RR42_RS28005 +0.8 1.3 phosphonate/organophosphate ester transporter subunit compare
RR42_RS09580 +0.8 1.1 hypothetical protein compare
RR42_RS31790 +0.8 1.4 nitrite reductase compare
RR42_RS23765 +0.8 3.0 tRNA-Gly compare
RR42_RS33910 +0.8 2.2 LysR family transcriptional regulator compare
RR42_RS08590 +0.7 1.3 baseplate assembly protein compare
RR42_RS34680 +0.7 1.0 short-chain dehydrogenase compare
RR42_RS15060 +0.7 2.2 membrane protein compare
RR42_RS27290 +0.7 2.1 hypothetical protein compare
RR42_RS07940 +0.7 1.5 ABC transporter permease compare
RR42_RS00600 +0.7 0.3 DeoR family transcriptional regulator compare
RR42_RS02470 +0.7 1.2 dihydroneopterin triphosphate pyrophosphatase compare
RR42_RS13130 +0.7 1.3 membrane protein compare
RR42_RS33500 +0.7 5.3 4-hydroxyphenylpyruvate dioxygenase compare
RR42_RS33595 +0.7 2.6 hypothetical protein compare
RR42_RS29790 +0.7 2.7 hypothetical protein compare
RR42_RS23955 +0.7 2.8 hypothetical protein compare
RR42_RS08000 +0.7 0.9 hypothetical protein compare
RR42_RS25965 +0.7 1.8 LuxR family transcriptional regulator compare
RR42_RS05935 +0.7 3.1 membrane protein compare
RR42_RS05965 +0.7 1.5 malonic semialdehyde reductase compare
RR42_RS06020 +0.7 0.8 Fe-S cluster assembly transcriptional regulator IscR compare
RR42_RS05080 +0.7 3.2 3-hydroxyanthranilate 3,4-dioxygenase compare
RR42_RS19465 +0.7 4.9 AsnC family transcriptional regulator compare
RR42_RS23595 +0.7 2.2 dTDP-4-dehydrorhamnose 3,5-epimerase compare
RR42_RS34060 +0.7 1.2 alpha/beta hydrolase compare
RR42_RS31435 +0.7 1.0 hypothetical protein compare
RR42_RS05700 +0.7 2.9 hypothetical protein compare
RR42_RS31715 +0.7 2.7 hypothetical protein compare
RR42_RS16925 +0.7 2.5 histidine utilization repressor compare
RR42_RS23220 +0.7 1.8 MarR family transcriptional regulator compare
RR42_RS14520 +0.7 1.4 mobilization protein compare
RR42_RS08320 +0.7 1.6 hypothetical protein compare
RR42_RS15795 +0.7 2.6 spore coat protein compare
RR42_RS13740 +0.7 3.3 isochorismatase compare
RR42_RS35995 +0.6 1.3 membrane protein compare
RR42_RS27115 +0.6 2.4 amino acid ABC transporter ATP-binding protein compare
RR42_RS33040 +0.6 1.4 hypothetical protein compare
RR42_RS20855 +0.6 3.3 cold-shock protein compare
RR42_RS03530 +0.6 0.8 hypothetical protein compare
RR42_RS33270 +0.6 1.6 hypothetical protein compare
RR42_RS32720 +0.6 2.4 glyoxalase compare
RR42_RS16620 +0.6 1.1 hypothetical protein compare
RR42_RS33495 +0.6 5.3 L-phenylalanine:H+ symporter AroP (from data) compare
RR42_RS25600 +0.6 1.4 AraC family transcriptional regulator compare
RR42_RS14905 +0.6 1.4 hypothetical protein compare
RR42_RS15790 +0.6 2.8 aminotransferase class III compare
RR42_RS22765 +0.6 2.3 carboxyvinyl-carboxyphosphonate phosphorylmutase compare
RR42_RS15800 +0.6 1.8 aldo/keto reductase compare
RR42_RS02030 +0.6 1.9 membrane protein compare
RR42_RS33690 +0.6 1.5 phosphate acetyltransferase compare
RR42_RS23550 +0.6 2.3 flagellar export protein FliJ compare
RR42_RS12085 +0.6 1.2 glyoxalase compare
RR42_RS14930 +0.6 2.4 biopolymer transporter ExbD compare
RR42_RS32460 +0.6 1.7 LysR family transcriptional regulator compare
RR42_RS18350 +0.6 1.9 NADPH:quinone dehydrogenase compare
RR42_RS30965 +0.6 2.3 hypothetical protein compare
RR42_RS04060 +0.6 1.1 hypothetical protein compare
RR42_RS30285 +0.6 1.7 amidohydrolase compare
RR42_RS07115 +0.6 0.7 hypothetical protein compare
RR42_RS27060 +0.6 0.9 cation transporter compare
RR42_RS21180 +0.6 1.8 GNAT family acetyltransferase compare
RR42_RS06505 +0.6 2.6 hypothetical protein compare
RR42_RS31695 +0.6 2.1 hypothetical protein compare
RR42_RS32735 +0.6 1.6 3-methylcrotonyl-CoA carboxylase compare
RR42_RS06865 +0.6 1.7 hypothetical protein compare
RR42_RS11260 +0.6 3.0 Methylisocitrate lyase (EC 4.1.3.30) (from data) compare
RR42_RS05005 +0.6 3.0 NAD(FAD)-utilizing dehydrogenase compare
RR42_RS23870 +0.6 1.7 hypothetical protein compare
RR42_RS33695 +0.6 1.8 membrane protein compare
RR42_RS13365 +0.6 1.4 peptidase P60 compare
RR42_RS02840 +0.6 2.2 cation transporter compare
RR42_RS11475 +0.6 3.0 pyrroloquinoline quinone biosynthesis protein PqqE compare
RR42_RS23405 +0.6 2.9 hypothetical protein compare
RR42_RS12130 +0.6 0.9 hypothetical protein compare
RR42_RS27395 +0.6 1.9 GntR family transcriptional regulator compare
RR42_RS07815 +0.6 2.2 glutamine ABC transporter ATP-binding protein compare
RR42_RS35190 +0.6 3.3 LacI family transcriptional regulator compare
RR42_RS33070 +0.6 1.1 oxidoreductase compare
RR42_RS35100 +0.5 2.6 TetR family transcriptional regulator compare
RR42_RS07245 +0.5 1.1 hypothetical protein compare
RR42_RS23300 +0.5 2.8 hypothetical protein compare
RR42_RS05810 +0.5 1.1 RNA polymerase sigma factor compare
RR42_RS34935 +0.5 0.9 cytochrome C oxidase subunit IV compare
RR42_RS34690 +0.5 1.4 permease compare
RR42_RS09830 +0.5 1.9 DNA-binding protein compare
RR42_RS31975 +0.5 1.7 fatty acid--CoA ligase compare
RR42_RS07455 +0.5 3.0 ABC transporter substrate-binding protein compare
RR42_RS25840 +0.5 2.4 ArsR family transcriptional regulator compare
RR42_RS35600 +0.5 1.0 hypothetical protein compare
RR42_RS26555 +0.5 0.9 tRNA-Met compare
RR42_RS29490 +0.5 1.2 toxin HipA compare
RR42_RS27675 +0.5 2.8 esterase compare
RR42_RS27855 +0.5 1.5 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase compare
RR42_RS02540 +0.5 2.1 taurine ABC transporter permease compare
RR42_RS24080 +0.5 2.2 hypothetical protein compare
RR42_RS24480 +0.5 2.6 hypothetical protein compare
RR42_RS09240 +0.5 0.6 MFS transporter compare
RR42_RS37455 +0.5 1.1 hypothetical protein compare
RR42_RS01970 +0.5 2.5 maleylacetoacetate isomerase compare
RR42_RS03945 +0.5 2.4 chloride channel protein compare
RR42_RS22230 +0.5 1.0 hypothetical protein compare
RR42_RS08770 +0.5 0.9 2-nitropropane dioxygenase compare
RR42_RS24190 +0.5 1.6 LysR family transcriptional regulator compare
RR42_RS05780 +0.5 1.8 hypothetical protein compare
RR42_RS20825 +0.5 2.1 addiction module antitoxin compare
RR42_RS07265 +0.5 1.0 hypothetical protein compare
RR42_RS09780 +0.5 1.4 hypothetical protein compare
RR42_RS23140 +0.5 0.6 peptidylprolyl isomerase compare
RR42_RS36370 +0.5 1.9 dihydrodipicolinate synthase compare
RR42_RS15495 +0.5 1.8 hypothetical protein compare
RR42_RS04380 +0.5 2.1 LysR family transcriptional regulator compare
RR42_RS10005 +0.5 1.8 3-oxoadipate CoA-transferase compare
RR42_RS00975 +0.5 2.1 MBL fold metallo-hydrolase compare
RR42_RS03415 +0.5 2.9 N-acetylmuramoyl-L-alanine amidase compare
RR42_RS26925 +0.5 1.4 membrane protein compare
RR42_RS14880 +0.5 1.1 hypothetical protein compare
RR42_RS09255 +0.5 1.7 copper resistance protein CopQ compare
RR42_RS08795 +0.5 1.3 molybdopterin-guanine dinucleotide biosynthesis protein B compare
RR42_RS31245 +0.5 1.0 membrane protein compare
RR42_RS24235 +0.5 1.9 hypothetical protein compare
RR42_RS15610 +0.5 2.3 cupin compare
RR42_RS35900 +0.5 3.3 hypothetical protein compare
RR42_RS00425 +0.5 2.5 ABC transporter substrate-binding protein compare
RR42_RS00020 +0.5 2.3 hypothetical protein compare
RR42_RS22535 +0.5 1.0 ArsR family transcriptional regulator compare
RR42_RS06745 +0.5 2.0 hypothetical protein compare
RR42_RS23350 +0.5 1.6 flagellar biosynthesis protein FliR compare
RR42_RS36560 +0.5 1.2 ABC transporter substrate-binding protein compare
RR42_RS05095 +0.5 2.1 4-hyroxy-2-oxovalerate aldolase compare
RR42_RS07190 +0.5 2.1 hypothetical protein compare
RR42_RS23355 +0.5 0.6 flagellar biosynthetic protein FliQ compare
RR42_RS22745 +0.5 1.2 phosphoribosylglycinamide formyltransferase compare
RR42_RS01485 +0.5 1.5 phosphonate transporter compare
RR42_RS31915 +0.5 1.9 short-chain dehydrogenase compare
RR42_RS27480 +0.5 1.2 AraC family transcriptional regulator compare
RR42_RS36115 +0.5 1.8 hypothetical protein compare
RR42_RS04270 +0.5 2.7 MFS transporter compare
RR42_RS21685 +0.5 1.2 hypothetical protein compare
RR42_RS18610 +0.5 2.0 hypothetical protein compare
RR42_RS35980 +0.5 1.7 membrane protein compare
RR42_RS28270 +0.5 1.4 TetR family transcriptional regulator compare
RR42_RS00900 +0.5 1.6 2-hydroxychromene-2-carboxylate isomerase compare
RR42_RS35725 +0.5 0.9 flagellar biosynthesis protein FlgB compare
RR42_RS12080 +0.5 1.1 lipase compare
RR42_RS01750 +0.5 3.8 hypothetical protein compare
RR42_RS24500 +0.5 2.0 hypothetical protein compare
RR42_RS18310 +0.5 0.9 indole-3-glycerol-phosphate synthase compare
RR42_RS31885 +0.5 1.1 sialidase compare
RR42_RS30295 +0.5 1.6 ABC transporter substrate-binding protein compare
RR42_RS09365 +0.5 2.3 multidrug DMT transporter permease compare
RR42_RS20880 +0.5 1.1 hypothetical protein compare
RR42_RS36045 +0.5 2.2 hypothetical protein compare
RR42_RS12715 +0.5 1.5 peptidylprolyl isomerase compare
RR42_RS33450 +0.5 2.2 alanine racemase compare
RR42_RS24820 +0.5 1.2 hypothetical protein compare
RR42_RS01510 +0.5 1.9 N-acetylglutamate synthase compare
RR42_RS05420 +0.5 1.5 membrane protein compare
RR42_RS37420 +0.5 1.3 AraC family transcriptional regulator compare
RR42_RS08790 +0.5 0.9 zinc-binding protein compare
RR42_RS30675 +0.5 1.6 hypothetical protein compare
RR42_RS36445 +0.5 1.5 acetyl-CoA acetyltransferase compare
RR42_RS10620 +0.5 1.8 amidohydrolase compare
RR42_RS25120 +0.5 1.8 IclR family transcriptional regulator compare
RR42_RS35440 +0.5 2.3 MBL fold metallo-hydrolase compare


Specific Phenotypes

For 5 genes in this experiment

For nitrogen source L-Tryptophan in Cupriavidus basilensis FW507-4G11

For nitrogen source L-Tryptophan across organisms