Experiment set3IT015 for Rhodospirillum rubrum S1H

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Succinic Acid 31.25 mM; anaerobic

200 most important genes:

  gene name fitness t score description  
Rru_A0619 -7.4 -2.1 Magnesium protoporphyrin O-methyltransferase (NCBI) compare
Rru_A0574 -5.0 -1.8 Carboxylyase-related protein (NCBI) compare
Rru_A0021 -4.5 -1.8 Transcriptional Regulator, MarR family (NCBI) compare
Rru_A2510 -4.3 -2.2 hypothetical protein (NCBI) compare
Rru_A3380 -4.3 -2.8 hypothetical protein (NCBI) compare
Rru_A1894 -3.8 -5.5 heavy metal translocating P-type ATPase (NCBI) compare
Rru_A0670 -3.7 -2.5 Cobalbumin biosynthesis enzyme (NCBI) compare
Rru_A2992 -3.6 -4.4 Precorrin-6Y C5,15-methyltransferase (decarboxylating) (NCBI) compare
Rru_A0058 -3.5 -0.8 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A1837 -3.5 -4.2 Porphobilinogen synthase (NCBI) compare
Rru_A0596 -3.4 -4.0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A3558 -3.2 -1.7 Protein of unknown function UPF0005 (NCBI) compare
Rru_A2507 -3.1 -10.1 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A1620 -3.0 -0.8 hypothetical protein (NCBI) compare
Rru_A3191 -3.0 -9.3 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1021 -3.0 -1.4 Sigma 32 (RpoH) (NCBI) compare
Rru_A0397 -3.0 -5.6 Argininosuccinate lyase (NCBI) compare
Rru_A1827 -2.9 -10.1 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A2902 -2.9 -0.8 hypothetical protein (NCBI) compare
Rru_A3642 -2.8 -0.8 Negative regulator of class I heat shock protein (NCBI) compare
Rru_A2936 -2.7 -8.9 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A0514 -2.7 -6.4 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A1190 -2.7 -1.0 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A3393 -2.6 -2.8 Penicillin-binding protein 1A (NCBI) compare
Rru_A1849 -2.6 -1.8 Recombination protein O, RecO (NCBI) compare
Rru_A2370 -2.6 -1.4 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A3190 -2.5 -2.0 Aspartate carbamoyltransferase (NCBI) compare
Rru_A3800 -2.5 -1.5 hypothetical protein (NCBI) compare
Rru_A3276 -2.5 -4.8 Ornithine carbamoyltransferase (NCBI) compare
Rru_A0683 -2.3 -0.5 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A1786 -2.3 -12.1 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A1928 -2.2 -8.5 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A1051 -2.2 -2.4 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A2981 -2.2 -3.7 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide (NCBI) compare
Rru_A1648 -2.2 -1.4 Helix-turn-helix protein, CopG (NCBI) compare
Rru_A2988 -2.1 -2.0 Precorrin-6X reductase (NCBI) compare
Rru_A3547 -2.1 -3.0 hypothetical protein (NCBI) compare
Rru_A0394 -2.1 -2.1 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A2404 -2.1 -7.1 Phosphoribulokinase (NCBI) compare
Rru_A1890 -2.1 -1.9 hypothetical protein (NCBI) compare
Rru_A0404 -2.1 -14.6 Amidophosphoribosyl transferase (NCBI) compare
Rru_A2421 -2.1 -4.3 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A2403 -2.1 -9.4 Inositol phosphatase/fructose-1,6-bisphosphatase (NCBI) compare
Rru_A0613 -2.0 -3.2 Bacteriochlorophyll 4-vinyl reductase (NCBI) compare
Rru_A0469 -2.0 -8.0 Ketol-acid reductoisomerase (NCBI) compare
Rru_A1691 -2.0 -6.5 Spermine synthase (NCBI) compare
Rru_A2886 -2.0 -13.0 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A2524 -2.0 -7.6 Peptidase U32 (NCBI) compare
Rru_A3264 -2.0 -5.5 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A2525 -2.0 -6.9 Peptidase U32 (NCBI) compare
Rru_A3594 -1.9 -1.7 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A1189 -1.9 -9.3 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A1895 -1.9 -1.6 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A3214 -1.9 -6.1 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A2400 -1.8 -7.1 Ribulose-bisphosphate carboxylase, form II (NCBI) compare
Rru_A3266 -1.8 -6.5 Homoserine O-acetyltransferase (NCBI) compare
Rru_A3165 -1.8 -3.4 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A2847 -1.7 -0.8 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A1530 -1.7 -9.6 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A3162 -1.7 -7.2 Prephenate dehydratase (NCBI) compare
Rru_A3173 -1.7 -5.0 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A3548 -1.7 -5.9 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A0580 -1.7 -2.2 OsmC-like protein (NCBI) compare
Rru_A2100 -1.7 -2.7 Protein of unknown function DUF81 (NCBI) compare
Rru_A3382 -1.7 -4.6 Cobalamin biosynthesis protein CbiB (NCBI) compare
Rru_A2937 -1.7 -1.8 Asparagine synthase, glutamine-hydrolyzing (NCBI) compare
Rru_A3267 -1.7 -5.2 Methionine biosynthesis MetW (NCBI) compare
Rru_A2990 -1.7 -5.2 precorrin-2 C20-methyltransferase (NCBI) compare
Rru_A1552 -1.6 -1.5 Peptidase S16, ATP-dependent protease La (NCBI) compare
Rru_A3468 -1.6 -1.6 Transcriptional Regulator, AsnC family (NCBI) compare
Rru_A2167 -1.6 -4.9 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A3424 -1.6 -2.4 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A0622 -1.6 -5.6 Light-independent protochlorophyllide reductase, B subunit (NCBI) compare
Rru_A3751 -1.6 -7.8 Argininosuccinate synthase (NCBI) compare
Rru_A0485 -1.6 -3.4 Magnesium chelatase ATPase subunit I (NCBI) compare
Rru_A3168 -1.6 -3.7 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3427 -1.6 -9.8 Tryptophan synthase, beta chain (NCBI) compare
Rru_A0624 -1.6 -5.4 2-vinyl bacteriochlorophyllide hydratase (NCBI) compare
Rru_B0049 -1.6 -1.4 dTDP-4-dehydrorhamnose reductase (NCBI) compare
Rru_A2772 -1.6 -1.6 ATP phosphoribosyltransferase (NCBI) compare
Rru_A2363 -1.6 -4.9 Endonuclease/exonuclease/phosphatase (NCBI) compare
Rru_A3341 -1.6 -1.2 Acetylglutamate kinase (NCBI) compare
Rru_A0652 -1.6 -1.2 Pseudouridine synthase, Rsu (NCBI) compare
Rru_A2974 -1.6 -6.1 Photosynthetic reaction centre M subunit (NCBI) compare
Rru_A0486 -1.6 -5.0 von Willebrand factor, type A (NCBI) compare
Rru_A3801 -1.6 -1.7 Enoyl-CoA hydratase/isomerase (NCBI) compare
Rru_A1191 -1.5 -6.8 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A0621 -1.5 -8.4 Magnesium-chelatase, subunit H (NCBI) compare
Rru_A3428 -1.5 -6.3 Tryptophan synthase (NCBI) compare
Rru_A0627 -1.5 -4.7 Bacteriochlorophyll/chlorophyll synthetase (NCBI) compare
Rru_A2885 -1.5 -4.9 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A1608 -1.5 -6.5 MscS Mechanosensitive ion channel (NCBI) compare
Rru_A0654 -1.5 -2.6 Multiple antibiotic resistance (MarC)-related proteins (NCBI) compare
Rru_A2975 -1.5 -5.8 Photosynthetic reaction centre protein L subunit (NCBI) compare
Rru_A0671 -1.4 -3.4 cobalamin synthesis CobW protein (NCBI) compare
Rru_A0700 -1.4 -0.7 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A1678 -1.4 -2.1 Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) compare
Rru_A0155 -1.4 -1.7 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A0625 -1.4 -1.8 hypothetical protein (NCBI) compare
Rru_A1432 -1.4 -6.7 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A3533 -1.4 -3.8 hypothetical protein (NCBI) compare
Rru_A0159 -1.3 -1.4 Exodeoxyribonuclease VII (NCBI) compare
Rru_A3227 -1.3 -5.0 conserved hypothetical protein, potential methyltransferase (NCBI) compare
Rru_A2416 -1.3 -1.6 hypothetical protein (NCBI) compare
Rru_A2987 -1.3 -1.9 hypothetical protein (NCBI) compare
Rru_A1286 -1.3 -0.5 hypothetical protein (NCBI) compare
Rru_A1627 -1.3 -1.0 hypothetical protein (NCBI) compare
Rru_A3268 -1.3 -1.4 hypothetical protein (NCBI) compare
Rru_A3397 -1.3 -1.6 hypothetical protein (NCBI) compare
Rru_A1611 -1.3 -1.1 Cobalamin synthesis protein/P47K (NCBI) compare
Rru_A0515 -1.3 -2.1 HAD-superfamily subfamily IIA hydrolase (NCBI) compare
Rru_A0618 -1.3 -5.7 PUCC protein (NCBI) compare
Rru_B0038 -1.2 -1.1 dTDP-4-dehydrorhamnose 3,5-epimerase (NCBI) compare
Rru_A2549 -1.2 -4.4 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A2798 -1.2 -2.3 hypothetical protein (NCBI) compare
Rru_A1572 -1.2 -2.2 Glyoxalase/bleomycin resistance protein/dioxygenase (NCBI) compare
Rru_A2978 -1.2 -4.2 Chlorophyllide reductase subunit Z (NCBI) compare
Rru_A1532 -1.2 -3.0 TPR repeat (NCBI) compare
Rru_A3206 -1.2 -2.0 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A1677 -1.2 -2.1 Signal transduction histidine kinase, nitrogen specific, NtrB (NCBI) compare
Rru_A0672 -1.2 -1.1 hypothetical protein (NCBI) compare
Rru_A3627 -1.2 -2.7 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A0668 -1.2 -1.4 Cobalamin-5-phosphate synthase CobS (NCBI) compare
Rru_A2181 -1.2 -5.0 NAD(P) transhydrogenase, beta subunit (NCBI) compare
Rru_A2308 -1.1 -2.1 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A3640 -1.1 -1.2 Ham1-like protein (NCBI) compare
Rru_A2445 -1.1 -2.1 Protein of unknown function DUF140 (NCBI) compare
Rru_A1896 -1.1 -4.3 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A2163 -1.1 -1.0 conserved hypothetical protein RP631 (NCBI) compare
Rru_A0137 -1.1 -4.4 TRAP transporter solute receptor, TAXI family (NCBI) compare
Rru_A0467 -1.1 -6.1 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_B0050 -1.1 -2.0 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A3384 -1.1 -2.9 Precorrin-4 C11-methyltransferase region (NCBI) compare
Rru_A2795 -1.1 -1.9 hypothetical protein (NCBI) compare
Rru_A1537 -1.1 -1.2 hypothetical protein (NCBI) compare
Rru_A2085 -1.1 -1.2 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) compare
Rru_A1937 -1.1 -0.8 hypothetical protein (NCBI) compare
Rru_A1916 -1.1 -1.6 Ferredoxin (NCBI) compare
Rru_A3425 -1.1 -3.0 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A2399 -1.0 -2.4 conserved hypothetical protein VC1941 (NCBI) compare
Rru_A2183 -1.0 -3.0 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A1391 -1.0 -1.6 hypothetical protein (NCBI) compare
Rru_A3136 -1.0 -2.3 putative partition-related protein (NCBI) compare
Rru_A1105 -1.0 -2.1 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A3169 -1.0 -1.8 ABC transporter component (NCBI) compare
Rru_A2377 -1.0 -1.2 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A2980 -1.0 -3.6 Chlorophyllide reductase iron protein subunit X (NCBI) compare
Rru_A0603 -1.0 -1.8 Two component Transcriptional regulator, Winged helix family (NCBI) compare
Rru_A0180 -1.0 -1.0 hypothetical protein (NCBI) compare
Rru_A2907 -1.0 -0.8 Anti-Sigma-factor antagonist (STAS) domain protein (NCBI) compare
Rru_A3549 -1.0 -3.0 Cobyric acid synthase CobQ (NCBI) compare
Rru_A2731 -1.0 -1.0 Exopolysaccharide synthesis, ExoD (NCBI) compare
Rru_A0644 -1.0 -0.9 hypothetical protein (NCBI) compare
Rru_A2545 -1.0 -1.4 hypothetical protein (NCBI) compare
Rru_A1239 -1.0 -0.8 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A0164 -0.9 -4.1 Sulfate transporter/antisigma-factor antagonist (NCBI) compare
Rru_A1804 -0.9 -2.3 N-acetyltransferase (NCBI) compare
Rru_A1692 -0.9 -3.3 S-adenosylmethionine decarboxylase related (NCBI) compare
Rru_A0617 -0.9 -2.5 Photosynthetic reaction center, H-chain (NCBI) compare
Rru_A1839 -0.9 -1.3 TRAP-type C4-dicarboxylate transport system periplasmic component-like (NCBI) compare
Rru_A2479 -0.9 -4.1 Methylmalonyl-CoA mutase-like (NCBI) compare
Rru_A2539 -0.9 -0.9 hypothetical protein (NCBI) compare
Rru_A3158 -0.9 -1.9 hypothetical protein (NCBI) compare
Rru_A3773 -0.9 -1.1 CBS domain protein (NCBI) compare
Rru_A2480 -0.9 -1.2 Methylmalonyl-CoA mutase (NCBI) compare
Rru_A3450 -0.9 -2.5 Ribonuclease T2 (NCBI) compare
Rru_A3167 -0.9 -1.6 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A3502 -0.9 -0.4 hypothetical protein (NCBI) compare
Rru_A0075 -0.9 -2.1 RNA-binding S4 (NCBI) compare
Rru_A1265 -0.9 -1.8 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A1470 -0.9 -1.5 hypothetical protein (NCBI) compare
Rru_A3550 -0.9 -2.3 Cobyric acid synthase CobQ (NCBI) compare
Rru_A1734 -0.9 -1.9 hypothetical protein (NCBI) compare
Rru_A3156 -0.8 -1.5 von Willebrand factor, type A (NCBI) compare
Rru_A1985 -0.8 -3.1 hypothetical protein (NCBI) compare
Rru_A0620 -0.8 -2.6 Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein (NCBI) compare
Rru_A0703 -0.8 -1.5 Molybdate ABC transporter, permease protein (NCBI) compare
Rru_A0801 -0.8 -1.4 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A1327 -0.8 -1.7 hypothetical protein (NCBI) compare
Rru_A0851 -0.8 -1.7 HPr kinase (NCBI) compare
Rru_A0024 -0.8 -1.9 peptidase (NCBI) compare
Rru_A1868 -0.8 -3.4 Peptidase M23B (NCBI) compare
Rru_A3054 -0.8 -0.6 Ribonuclease H (NCBI) compare
Rru_A1798 -0.8 -3.2 Type I secretion outer membrane protein, TolC (NCBI) compare
Rru_A3195 -0.8 -0.8 Helix-turn-helix protein, CopG (NCBI) compare
Rru_A3587 -0.8 -1.5 hypothetical protein (NCBI) compare
Rru_A2038 -0.8 -3.6 Glutamate-ammonia-ligase adenylyltransferase (NCBI) compare
Rru_A3139 -0.8 -2.7 Transcriptional Regulator, GntR family (NCBI) compare
Rru_A1206 -0.8 -0.5 hypothetical protein (NCBI) compare
Rru_A2446 -0.8 -1.8 ABC transporter component (NCBI) compare
Rru_A0969 -0.8 -1.9 VWA containing CoxE-like (NCBI) compare
Rru_A0206 -0.8 -1.1 Cobalt chelatase, pCobS small subunit (NCBI) compare
Rru_A1867 -0.8 -0.6 Protein of unknown function DUF583 (NCBI) compare
Rru_A2472 -0.8 -2.9 hypothetical protein (NCBI) compare
Rru_A2410 -0.8 -1.3 Homoserine dehydrogenase (NCBI) compare
Rru_A2983 -0.8 -0.5 Polyprenyl synthetase (NCBI) compare
Rru_A3164 -0.7 -0.8 hypothetical protein (NCBI) compare
Rru_A2098 -0.7 -2.5 Protein of unknown function DUF490 (NCBI) compare
Rru_A2753 -0.7 -2.2 Transglutaminase-like (NCBI) compare
Rru_A1321 -0.7 -1.0 Biotin--acetyl-CoA-carboxylase ligase (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Succinic Acid across organisms