Experiment set3IT014 for Sinorhizobium meliloti 1021

Compare to:

L-Leucine nitrogen source

200 most important genes:

  gene name fitness t score description  
SMc00236 -8.8 -3.9 Indole-3-glycerol phosphate synthase compare
SMc01726 -7.8 -3.3 acetylglutamate kinase compare
SMc01801 -7.2 -2.5 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02572 -7.0 -3.0 imidazole glycerol phosphate synthase subunit HisH compare
SMc00495 -7.0 -3.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc01494 -6.9 -10.6 phosphoserine phosphatase compare
SMc00963 -6.7 -2.9 hypothetical protein compare
SMc01004 -6.6 -9.0 phosphoribosyl-AMP cyclohydrolase compare
SMc02725 -6.5 -12.5 anthranilate synthase compare
SMc03981 -6.3 -3.8 phosphoglycerate kinase compare
SMc00235 -6.2 -9.1 anthranilate phosphoribosyltransferase compare
SMc00412 -6.1 -5.1 orotidine 5'-phosphate decarboxylase compare
SMa1635 -6.0 -1.2 hypothetical protein compare
SMc02753 -6.0 -1.2 PTS system transporter subunit IIA compare
SMc00993 -6.0 -9.7 phosphoribosylamine--glycine ligase compare
SMc03777 -6.0 -8.1 gamma-glutamyl phosphate reductase compare
SMc01361 -5.7 -5.4 dihydroorotase compare
SMc03229 -5.7 -1.9 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc04045 -5.6 -8.9 dihydroxy-acid dehydratase compare
SMc04005 -5.6 -6.7 pyruvate kinase compare
SMc02569 -5.6 -3.4 imidazole glycerol phosphate synthase subunit HisF compare
SMc02138 -5.5 -7.9 acetylornithine transaminase compare
SMc00815 -5.5 -1.9 inosine 5'-monophosphate dehydrogenase compare
SMc01431 -5.5 -16.6 acetolactate synthase 3 catalytic subunit compare
SMc00493 -5.5 -6.4 phosphoribosylformylglycinamidine synthase I compare
SMc00918 -5.4 -7.2 ATP phosphoribosyltransferase regulatory subunit compare
SMc03979 -5.4 -2.1 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00488 -5.4 -13.6 phosphoribosylformylglycinamidine synthase II compare
SMc01447 -5.3 -1.1 hypothetical protein compare
SMc00640 -5.2 -9.4 phosphoserine aminotransferase compare
SM_b21174 -5.2 -4.6 phosphate uptake ABC transporter permease compare
SMc00641 -5.2 -7.8 D-3-phosphoglycerate dehydrogenase compare
SM_b21176 -5.2 -5.0 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00917 -5.1 -4.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02307 -5.1 -8.6 histidinol dehydrogenase compare
SMc03776 -5.0 -2.2 gamma-glutamyl kinase compare
SMc00614 -5.0 -6.0 phosphoribosylglycinamide formyltransferase compare
SMc02766 -4.9 -16.3 tryptophan synthase subunit beta compare
SMc00615 -4.9 -12.4 phosphoribosylaminoimidazole synthetase compare
SMc02767 -4.8 -6.3 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00554 -4.7 -8.2 amidophosphoribosyltransferase compare
SMc02899 -4.7 -8.8 prephenate dehydratase compare
SMc03763 -4.7 -2.8 cytosine-specific methyltransferase compare
SMc01360 -4.7 -2.9 aspartate carbamoyltransferase catalytic subunit compare
SMc02510 -4.7 -0.9 ferric uptake regulation protein compare
SMc02165 -4.7 -11.5 orotate phosphoribosyltransferase compare
SMc02909 -4.7 -1.8 transglycosylase transmembrane protein compare
SMc01881 -4.6 -3.3 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc03100 -4.6 -1.6 hypothetical protein compare
SMa0753 -4.6 -0.9 hypothetical protein compare
SMc01569 -4.6 -1.3 carbamoyl phosphate synthase small subunit compare
SMc02140 -4.6 -1.8 phosphate regulon transcriptional regulatory protein compare
SMc02765 -4.6 -10.3 tryptophan synthase subunit alpha compare
SMc02141 -4.5 -4.9 phosphate transporter PhoU compare
SMc00726 -4.5 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc03849 -4.4 -1.5 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc00494 -4.4 -1.5 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc02147 -4.3 -8.4 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02245 -4.2 -3.9 dihydroorotate dehydrogenase 2 compare
SMc00928 -4.2 -1.2 signal peptide protein compare
SMc03895 -4.2 -12.8 pyruvate carboxylase compare
SMc03978 -4.2 -3.8 transketolase compare
SMa1002 -4.2 -1.9 hypothetical protein compare
SMc02137 -4.1 -2.3 ornithine carbamoyltransferase compare
SMc04001 -4.1 -0.8 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc00588 -4.1 -2.1 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
SMc02570 -4.0 -4.9 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00293 -4.0 -8.2 homoserine dehydrogenase compare
SMc02407 -4.0 -8.8 hypothetical protein compare
SMc04346 -4.0 -5.0 ketol-acid reductoisomerase compare
SMc04389 -3.9 -2.6 hydroxypyruvate reductase compare
SMc02166 -3.9 -7.6 dihydroorotase compare
SMc01215 -3.9 -5.3 carbamoyl phosphate synthase large subunit compare
SMc02246 -3.9 -0.8 hypothetical protein compare
SMc02901 -3.9 -0.8 hypothetical protein compare
SMa0789 -3.9 -2.9 GntR family transcriptional regulator compare
SMc00711 -3.8 -2.7 cyclohexadienyl dehydrogenase compare
SMc04002 -3.8 -5.0 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc01880 -3.8 -3.1 pantoate--beta-alanine ligase compare
SMc04088 -3.8 -5.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc03797 -3.6 -6.3 homoserine O-succinyltransferase compare
SMc01042 -3.6 -5.5 nitrogen regulation protein compare
SMc01948 -3.5 -5.8 high-affinity branched-chain amino acid ABC transporter ATP-binding protein conserved
SMc01770 -3.5 -1.2 serine hydroxymethyltransferase compare
SMc00017 -3.5 -1.0 homoserine kinase compare
SMc02694 -3.5 -1.0 ATP-dependent Clp protease adaptor compare
SMc03836 -3.5 -0.9 acyl-CoA thioesterase i protein compare
SMc02145 -3.4 -0.9 signal peptide protein compare
SMc00143 -3.3 -1.3 molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
SM_b20948 -3.3 -1.6 glucosyltransferase compare
SMc01850 -3.3 -3.3 hypothetical protein compare
SMa0674 -3.2 -1.3 hypothetical protein compare
SM_b21175 -3.2 -2.4 phosphate uptake ABC transporter permease compare
SMc01124 -3.2 -7.3 PII uridylyl-transferase compare
SMc01043 -3.2 -7.4 nitrogen assimilation regulatory protein compare
SMc01843 -3.1 -9.0 5,10-methylenetetrahydrofolate reductase compare
SM_b21177 -3.1 -5.6 phosphate uptake ABC transporter ATP-binding protein compare
SMc01187 -3.0 -1.7 rare lipoprotein A compare
SMc03070 -3.0 -7.0 glucose-6-phosphate 1-dehydrogenase compare
SMc02451 -3.0 -1.1 hypothetical protein compare
SMc02240 -3.0 -5.8 hypothetical protein conserved
SMc03112 -3.0 -9.6 B12-dependent methionine synthase compare
SMc02707 -2.9 -3.2 hypothetical protein compare
SMc02227 -2.9 -3.8 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc00013 -2.9 -1.8 cytochrome C oxidase subunit III transmembrane protein compare
SMc01430 -2.9 -3.8 acetolactate synthase 3 regulatory subunit compare
SMc01578 -2.9 -7.5 aspartate aminotransferase compare
SMc02228 -2.8 -5.6 acetyl-CoA acetyltransferase compare
SMc01595 -2.8 -3.0 sensor histidine kinase transmembrane protein compare
SMc03068 -2.8 -5.7 phosphogluconate dehydratase compare
SMc01438 -2.8 -4.7 protease precursor signal peptide protein compare
SMc02217 -2.7 -4.5 O-succinylhomoserine sulfhydrylase compare
SMc02058 -2.7 -2.4 YAJC protein compare
SMc02983 -2.7 -5.0 ornithine, DAP, or arginine decarboxylase compare
SMc04404 -2.7 -1.0 amino acid efflux transmembrane protein compare
SM_b21347 -2.7 -1.8 pectin degradation protein compare
SMc02229 -2.6 -6.5 acyl-CoA dehydrogenase compare
SMc00876 -2.6 -4.9 ATP-binding MRP protein compare
SMc00450 -2.6 -1.3 protoheme IX farnesyltransferase compare
SM_b22023 -2.6 -1.7 molecular chaperone GroES compare
SMc00295 -2.5 -0.7 hypothetical protein compare
SMc03826 -2.5 -2.6 argininosuccinate synthase compare
SM_b21125 -2.5 -4.9 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) (from data) compare
SMc01147 -2.5 -4.0 coproporphyrinogen III oxidase compare
SMc00296 -2.5 -5.5 POLY3-hydroxybutyrate polymerase compare
SMc02641 -2.5 -3.8 UDP-glucose 6-dehydrogenase compare
SMc02373 -2.5 -1.4 hypothetical protein compare
SMc00414 -2.4 -6.4 hypothetical protein compare
SMa1174 -2.4 -1.6 hypothetical protein compare
SMc02102 -2.4 -3.6 hypothetical protein compare
SM_b21126 -2.3 -1.9 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) compare
SM_b21476 -2.3 -3.4 hypothetical protein compare
SMc02640 -2.3 -5.0 UDP-glucuronic acid epimerase compare
SMc02833 -2.3 -1.9 penicillin-insensitive murein endopeptidase compare
SMc03878 -2.3 -2.6 acetoacetyl-CoA reductase compare
SMc00709 -2.2 -2.0 hypothetical protein compare
SM_b20452 -2.2 -2.5 hypothetical protein compare
SMc02232 -2.2 -2.4 hypothetical protein compare
SMa1413 -2.2 -2.0 hypothetical protein compare
SM_b20302 -2.2 -1.9 hypothetical protein compare
SMc03967 -2.2 -1.6 Holliday junction resolvase compare
SMc01949 -2.2 -3.6 high-affinity branched-chain amino acid ABC transporter ATP-binding protein compare
SMc04224 -2.1 -1.1 hypothetical protein compare
SMc02755 -2.0 -3.8 S-adenosyl-L-homocysteine hydrolase compare
SMc02234 -2.0 -1.8 hypothetical protein compare
SMc01950 -2.0 -7.6 high-affinity branched-chain amino acid ABC transporter permease compare
SMc04028 -2.0 -9.3 glutamate synthase compare
SM_b20904 -2.0 -1.9 sugar uptake ABC transporter ATP-binding protein compare
SMc01368 -2.0 -3.1 transport transmembrane protein compare
SMc00987 -2.0 -1.8 hypothetical protein compare
SMc00131 -2.0 -8.1 transcriptional regulator compare
SMc02425 -2.0 -3.2 transcriptional regulator compare
SM_b20540 -2.0 -1.0 hypothetical protein compare
SMc02142 -1.9 -3.1 phosphate transporter ATP-binding protein compare
SMc02574 -1.9 -2.6 imidazoleglycerol-phosphate dehydratase compare
SMc02071 -1.9 -3.0 hydrolase glycosidase compare
SMc04243 -1.9 -4.9 high-affinity zinc uptake system membrane ABC transporter protein compare
SMc04391 -1.9 -1.0 3-ketoacyl-ACP reductase compare
SMa1240 -1.9 -0.9 NapF ferredoxin component of periplasmic nitrate reductase compare
SMc02115 -1.8 -1.1 hypothetical protein compare
SM_b20897 -1.8 -1.7 hypothetical protein compare
SMc03850 -1.8 -1.1 heme exporter D (cytochrome C-type biogenesis protein) transmembrane compare
SMc02693 -1.8 -1.0 peptidyl-tRNA hydrolase compare
SMc02724 -1.8 -1.7 hypothetical protein compare
SMc04330 -1.8 -1.5 trimethylamine methyltransferase compare
SM_b21454 -1.8 -1.4 hypothetical protein compare
SMc02544 -1.8 -0.7 hypothetical protein compare
SM_b20413 -1.8 -0.7 hypothetical protein compare
SM_b21524 -1.7 -1.7 septum formation inhibitor compare
SMc04026 -1.7 -3.9 glutamate synthase compare
SMc01404 -1.7 -2.5 aspartate racemase compare
SM_b20184 -1.7 -1.6 ABC transporter ATP-binding protein compare
SMc01701 -1.7 -1.5 hypothetical protein compare
SMc01842 -1.7 -1.8 methyltransferase transcription regulator protein compare
SMc01613 -1.7 -2.7 ribose-5-phosphate isomerase B compare
SMc02144 -1.7 -3.7 phosphate ABC transporter permease compare
SMc01951 -1.7 -3.4 high-affinity branched-chain amino acid ABC transporter permease compare
SMc00025 -1.7 -3.7 pyruvate phosphate dikinase compare
SM_b21114 -1.7 -5.4 nitrate transport protein compare
SMc01342 -1.6 -3.7 hypothetical protein compare
SMa2299 -1.6 -1.9 hypothetical protein compare
SMc04182 -1.6 -1.6 hypothetical protein compare
SMc01440 -1.6 -3.2 hydrolase serine protease transmembrane protein compare
SMc00698 -1.6 -2.2 transcriptional regulator compare
SMc02149 -1.6 -1.3 hypothetical protein compare
SMc01206 -1.6 -1.2 queuine tRNA-ribosyltransferase compare
SM_b20414 -1.6 -1.2 hypothetical protein compare
SMc04462 -1.5 -2.0 glycerate dehydrogenase compare
SM_b20921 -1.5 -1.7 hypothetical protein compare
SMc01208 -1.5 -1.6 peptidyl-prolyl cis-trans isomerase B protein compare
SMc00067 -1.5 -7.6 outer-membranne lipoprotein compare
SMc00166 -1.5 -1.3 oxidoreductase NAD protein compare
SMa5018 -1.5 -1.0 hypothetical protein compare
SMc02434 -1.5 -1.3 hypothetical protein compare
SMc02515 -1.5 -2.1 hypothetical protein compare
SMc02787 -1.5 -1.6 hypothetical protein compare
SMc00302 -1.5 -1.2 hypothetical protein compare
SMc02856 -1.5 -4.7 penicillin-binding protein compare
SMc03153 -1.5 -1.8 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SMc02124 -1.5 -6.1 nitrite reductase compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source L-Leucine in Sinorhizobium meliloti 1021

For nitrogen source L-Leucine across organisms