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Experiment set3IT014 for
Methanococcus maripaludis S2
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H2 McCas, 5g/L bicarb, 40 psi H2CO2
200 most detrimental genes:
gene
name
fitness
t score
description
MMP
_RS01295
+1.4
11.2
hypothetical protein
compare
MMP
_RS08855
+1.4
10.2
hypothetical protein
compare
MMP
_RS01290
+1.3
11.0
class III signal peptide-containing protein
compare
MMP
_RS01285
+1.3
10.8
hypothetical protein
compare
MMP
_RS01310
+1.3
10.8
hypothetical protein
compare
MMP
_RS01305
+1.3
11.9
hypothetical protein
compare
MMP
_RS08860
+1.3
7.9
MinD/ParA family protein
compare
MMP
_RS01315
+1.3
11.7
DUF2341 domain-containing protein
compare
MMP
_RS01270
+1.2
10.6
prepilin peptidase
compare
MMP
_RS00240
+1.2
10.1
type II secretion system F family protein
compare
MMP
_RS01280
+1.2
9.6
DUF515 domain-containing protein
compare
MMP
_RS09055
+1.2
2.1
CAP domain-containing protein
compare
MMP
_RS00245
+1.2
10.6
type II secretion system F family protein
compare
MMP
_RS05635
+1.2
8.7
NAD-dependent epimerase/dehydratase family protein
compare
MMP
_RS01195
+1.1
2.3
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS07330
+1.1
10.3
membrane protein
compare
MMP
_RS01275
+1.1
6.5
class III signal peptide-containing protein
compare
MMP
_RS00250
+1.1
9.7
Flp pilus assembly complex ATPase component TadA
compare
MMP
_RS03125
+1.1
6.8
cell division ATPase MinD
compare
MMP
_RS08940
+1.0
2.2
MetS family NSS transporter small subunit
compare
MMP
_RS08675
+1.0
3.8
class III signal peptide-containing protein
compare
MMP
_RS01085
+1.0
2.9
hypothetical protein
compare
MMP
_RS02605
+1.0
1.2
MotA/TolQ/ExbB proton channel family protein
compare
MMP
_RS06035
+1.0
6.6
glycosyltransferase family 2 protein
compare
MMP
_RS06600
+0.9
2.0
class III signal peptide-containing protein
compare
MMP
_RS03320
+0.9
2.1
metal-dependent transcriptional regulator
compare
MMP
_RS00570
+0.9
2.0
protein-L-isoaspartate O-methyltransferase
compare
MMP
_RS08615
+0.8
1.3
flagellar protein G
compare
MMP
_RS06840
+0.8
1.0
DNA-directed RNA polymerase subunit N
compare
MMP
_RS05865
+0.8
1.9
hypothetical protein
compare
MMP
_RS05985
+0.7
2.0
hypothetical protein
compare
MMP
_RS08580
+0.7
2.9
flagellin
compare
MMP
_RS08750
+0.7
1.4
hypothetical protein
compare
MMP
_RS06760
+0.7
1.8
hypothetical protein
compare
MMP
_RS00140
+0.6
3.2
DUF192 domain-containing protein
compare
MMP
_RS09045
+0.6
4.5
class III signal peptide-containing protein
compare
MMP
_RS07840
+0.6
2.3
ribonuclease III
compare
MMP
_RS08315
+0.6
2.4
S-methyl-5-thioribose-1-phosphate isomerase
compare
MMP
_RS01075
+0.6
1.5
hypothetical protein
compare
MMP
_RS07890
+0.6
1.9
OB-fold nucleic acid binding domain-containing protein
compare
MMP
_RS06090
+0.6
2.5
iron ABC transporter permease
compare
MMP
_RS07900
+0.6
1.5
YeeE/YedE family protein
compare
MMP
_RS04630
+0.6
2.2
3'-5' exonuclease
compare
MMP
_RS07775
+0.6
2.0
alanine dehydrogenase
compare
MMP
_RS05580
+0.6
4.8
glycosyltransferase
compare
MMP
_RS03490
+0.5
1.5
DUF2115 domain-containing protein
compare
MMP
_RS08275
+0.5
3.6
hypothetical protein
compare
MMP
_RS06095
+0.5
3.3
ABC transporter ATP-binding protein
compare
MMP
_RS03300
+0.5
0.6
TOBE domain-containing protein
compare
MMP
_RS01125
+0.5
2.3
thioredoxin family protein
compare
MMP
_RS04410
+0.5
1.7
hypothetical protein
compare
MMP
_RS01660
+0.5
1.9
hypothetical protein
compare
MMP
_RS02545
+0.5
1.4
hypothetical protein
compare
MMP
_RS00965
+0.5
1.4
hypothetical protein
compare
MMP
_RS01790
+0.5
2.0
restriction endonuclease
compare
MMP
_RS07815
+0.5
0.9
DUF2120 domain-containing protein
compare
MMP
_RS01300
+0.5
4.0
hypothetical protein
compare
MMP
_RS08455
+0.5
1.8
multiprotein bridging factor aMBF1
compare
MMP
_RS07770
+0.5
3.0
alanine racemase
compare
MMP
_RS08640
+0.5
3.6
TIM barrel protein
compare
MMP
_RS07880
+0.5
2.0
AAA family ATPase
compare
MMP
_RS05095
+0.5
2.2
CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
compare
MMP
_RS01870
+0.5
2.2
acyl-CoA dehydratase activase
compare
MMP
_RS03625
+0.5
2.2
cell wall-binding protein
compare
MMP
_RS04145
+0.4
1.1
hypothetical protein
compare
MMP
_RS06525
+0.4
0.7
YciI family protein
compare
MMP
_RS06990
+0.4
2.0
CatB-related O-acetyltransferase
compare
MMP
_RS04610
+0.4
1.7
Dabb family protein
compare
MMP
_RS07095
+0.4
2.1
PspC domain-containing protein
compare
MMP
_RS00395
+0.4
1.0
MGMT family protein
compare
MMP
_RS01135
+0.4
2.9
molybdate ABC transporter substrate-binding protein
compare
MMP
_RS03080
+0.4
1.0
universal stress protein
compare
MMP
_RS08080
+0.4
2.4
YchF/TatD family DNA exonuclease
compare
MMP
_RS05085
+0.4
2.2
AAA family ATPase
compare
MMP
_RS01255
+0.4
1.4
amino acid ABC transporter ATP-binding protein
compare
MMP
_RS03840
+0.4
1.9
hypothetical protein
compare
MMP
_RS01320
+0.4
1.5
hypothetical protein
compare
MMP
_RS07800
+0.4
2.0
ATP-binding cassette domain-containing protein
compare
MMP
_RS08845
+0.4
2.1
archaellum operon transcriptional activator EarA family protein
compare
MMP
_RS08410
+0.4
1.9
DUF169 domain-containing protein
compare
MMP
_RS06115
+0.4
2.8
class II aldolase/adducin family protein
compare
MMP
_RS07905
+0.4
2.2
DUF3343 domain-containing protein
compare
MMP
_RS06735
+0.4
1.6
class I SAM-dependent rRNA methyltransferase
compare
MMP
_RS01490
+0.4
2.1
tetratricopeptide repeat protein
compare
MMP
_RS03965
+0.4
1.3
hypothetical protein
compare
MMP
_RS07895
+0.4
1.7
cytochrome c
compare
MMP
_RS03220
+0.4
1.4
RNA 2' 3'-cyclic phosphodiesterase
compare
MMP
_RS08830
+0.4
1.5
GTP-binding protein
compare
MMP
_RS00450
+0.4
0.8
4Fe-4S binding protein
compare
MMP
_RS06935
+0.4
1.9
protease complex subunit PrcB family protein
compare
MMP
_RS01440
+0.4
1.6
NAAT family transporter
compare
MMP
_RS00090
+0.4
1.5
CoA-binding protein
compare
MMP
_RS03065
+0.4
1.2
AzlC family ABC transporter permease
compare
MMP
_RS06065
+0.4
3.0
iron ABC transporter substrate-binding protein
compare
MMP
_RS02625
+0.4
2.0
ribonuclease H-like domain-containing protein
compare
MMP
_RS08775
+0.4
1.7
methanogenesis marker 9 domain-containing protein
compare
MMP
_RS01010
+0.3
2.3
DUF4352 domain-containing protein
compare
MMP
_RS02830
+0.3
2.1
DUF432 domain-containing protein
compare
MMP
_RS07590
+0.3
2.6
hypothetical protein
compare
MMP
_RS00295
+0.3
1.1
gamma carbonic anhydrase family protein
compare
MMP
_RS08285
+0.3
2.0
serine/threonine protein kinase
compare
MMP
_RS06100
+0.3
2.2
GNAT family N-acetyltransferase
compare
MMP
_RS07550
+0.3
1.9
L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
compare
MMP
_RS07910
+0.3
2.0
NAD(P)H-hydrate dehydratase
compare
MMP
_RS09035
+0.3
1.7
hypothetical protein
compare
MMP
_RS07805
+0.3
1.7
ABC transporter permease
compare
MMP
_RS00480
+0.3
1.6
hypothetical protein
compare
MMP
_RS06910
+0.3
2.2
RlmF-related methyltransferase
compare
MMP
_RS07685
+0.3
1.6
TIGR01212 family radical SAM protein
compare
MMP
_RS02530
+0.3
1.4
type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family
compare
MMP
_RS05965
+0.3
1.2
carboxymuconolactone decarboxylase family protein
compare
MMP
_RS02635
+0.3
2.1
class I SAM-dependent methyltransferase
compare
MMP
_RS03550
+0.3
0.5
DUF2124 domain-containing protein
compare
MMP
_RS00865
+0.3
1.4
SLC13 family permease
compare
MMP
_RS06605
+0.3
2.1
DUF5814 domain-containing protein
compare
MMP
_RS05785
+0.3
2.3
ATP-binding protein
compare
MMP
_RS02700
+0.3
1.7
formylmethanofuran dehydrogenase subunit C
compare
MMP
_RS00990
+0.3
1.1
hypothetical protein
compare
MMP
_RS06545
+0.3
1.6
ferredoxin family protein
compare
MMP
_RS06335
+0.3
1.3
HAD family hydrolase
compare
MMP
_RS01980
+0.3
2.5
trimeric intracellular cation channel family protein
compare
MMP
_RS05090
+0.3
1.9
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
compare
MMP
_RS00795
+0.3
1.6
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS08130
+0.3
2.3
IGHMBP2 family helicase
compare
MMP
_RS08235
+0.3
1.1
hypothetical protein
compare
MMP
_RS06320
+0.3
1.5
hypothetical protein
compare
MMP
_RS06385
+0.3
1.0
hypothetical protein
compare
MMP
_RS01185
+0.3
1.4
hypothetical protein
compare
MMP
_RS08400
+0.3
0.8
MJ0307 family thioredoxin
compare
MMP
_RS04125
+0.3
0.9
TetR/AcrR family transcriptional regulator
compare
MMP
_RS05720
+0.3
1.2
signal recognition particle subunit SRP19/SEC65 family protein
compare
MMP
_RS01055
+0.3
1.4
hypothetical protein
compare
MMP
_RS01155
+0.3
1.9
XRE family transcriptional regulator
compare
MMP
_RS08250
+0.3
1.5
pyruvate kinase
compare
MMP
_RS06175
+0.3
1.5
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS09025
+0.3
0.4
hypothetical protein
compare
MMP
_RS00710
+0.3
1.0
hypothetical protein
compare
MMP
_RS06555
+0.3
1.1
cupin domain-containing protein
compare
MMP
_RS06140
+0.3
0.9
radical SAM protein
compare
MMP
_RS06300
+0.3
1.3
ABC transporter substrate-binding protein
compare
MMP
_RS08490
+0.3
2.2
hypothetical protein
compare
MMP
_RS03900
+0.3
1.4
minichromosome maintenance protein MCM
compare
MMP
_RS06560
+0.3
1.9
hypothetical protein
compare
MMP
_RS05325
+0.3
1.6
hypothetical protein
compare
MMP
_RS01095
+0.3
1.0
iron ABC transporter permease
compare
MMP
_RS06680
+0.3
1.9
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS01645
+0.3
1.2
SWIM zinc finger family protein
compare
MMP
_RS03070
+0.3
1.2
AzlD domain-containing protein
compare
MMP
_RS06050
+0.3
1.2
ZIP family metal transporter
compare
MMP
_RS06720
+0.3
1.0
response regulator transcription factor
compare
MMP
_RS02025
+0.3
1.8
DNA-directed DNA polymerase
compare
MMP
_RS02385
+0.3
1.6
ATP-binding protein
compare
MMP
_RS04945
+0.3
1.6
hypothetical protein
compare
MMP
_RS00670
+0.3
0.8
TIM barrel protein
compare
MMP
_RS05100
+0.3
2.1
CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
compare
MMP
_RS06540
+0.3
0.9
3-methyl-2-oxobutanoate dehydrogenase subunit VorB
compare
MMP
_RS08535
+0.2
1.6
bis-aminopropyl spermidine synthase family protein
compare
MMP
_RS05435
+0.2
1.3
5'/3'-nucleotidase SurE
compare
MMP
_RS01100
+0.2
0.5
ABC transporter ATP-binding protein
compare
MMP
_RS08850
+0.2
2.1
hypothetical protein
compare
MMP
_RS02710
+0.2
1.5
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS00660
+0.2
1.7
alkaline phosphatase family protein
compare
MMP
_RS02740
+0.2
1.4
hypothetical protein
compare
MMP
_RS08930
+0.2
0.6
hypothetical protein
compare
MMP
_RS02295
+0.2
1.6
TatD family hydrolase
compare
MMP
_RS08760
+0.2
0.7
hypothetical protein
compare
MMP
_RS03570
+0.2
1.5
uracil-xanthine permease family protein
compare
MMP
_RS01080
+0.2
1.2
DUF2202 domain-containing protein
compare
MMP
_RS02455
+0.2
1.2
hypothetical protein
compare
MMP
_RS07115
+0.2
1.2
MBL fold metallo-hydrolase
compare
MMP
_RS08575
+0.2
2.0
hypothetical protein
compare
MMP
_RS04055
+0.2
0.5
hypothetical protein
compare
MMP
_RS01130
+0.2
1.6
flavoprotein
compare
MMP
_RS02825
+0.2
1.4
mechanosensitive ion channel family protein
compare
MMP
_RS01190
+0.2
1.5
cadmium-translocating P-type ATPase
compare
MMP
_RS07915
+0.2
1.5
DUF4870 domain-containing protein
compare
MMP
_RS08665
+0.2
1.8
hypothetical protein
compare
MMP
_RS07640
+0.2
1.3
mechanosensitive ion channel family protein
compare
MMP
_RS03525
+0.2
1.4
ketopantoate reductase family protein
compare
MMP
_RS05910
+0.2
0.7
cell division ATPase MinD
compare
MMP
_RS05115
+0.2
1.6
50S ribosomal protein L11 methyltransferase
compare
MMP
_RS07885
+0.2
0.9
tripartite tricarboxylate transporter permease
compare
MMP
_RS02770
+0.2
1.0
hypothetical protein
compare
MMP
_RS08610
+0.2
1.5
flagellar protein F
compare
MMP
_RS02670
+0.2
1.4
ATP-binding cassette domain-containing protein
compare
MMP
_RS05125
+0.2
1.5
D-aminoacyl-tRNA deacylase
compare
MMP
_RS07100
+0.2
1.5
hypothetical protein
compare
MMP
_RS02540
+0.2
0.9
DUF2283 domain-containing protein
compare
MMP
_RS06465
+0.2
1.6
NERD domain-containing protein
compare
MMP
_RS05130
+0.2
1.9
DUF2226 domain-containing protein
compare
MMP
_RS02305
+0.2
1.6
DUF378 domain-containing protein
compare
MMP
_RS06715
+0.2
1.6
cache domain-containing protein
compare
MMP
_RS01685
+0.2
0.7
indolepyruvate oxidoreductase subunit beta
compare
MMP
_RS03745
+0.2
1.3
phenylacetate--CoA ligase
compare
MMP
_RS08385
+0.2
0.9
ABC transporter substrate-binding protein
compare
MMP
_RS01515
+0.2
1.5
PINc/VapC family ATPase
compare
MMP
_RS02815
+0.2
0.5
hypothetical protein
compare
MMP
_RS03430
+0.2
1.4
bile acid:sodium symporter family protein
compare
MMP
_RS02765
+0.2
0.9
ABC transporter ATP-binding protein
compare
MMP
_RS01145
+0.2
1.2
ABC transporter ATP-binding protein
compare
Specific Phenotypes
For 1 genes in this experiment