Experiment set3IT013 for Rhodospirillum rubrum S1H

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Succinic Acid 31.25 mM; anaerobic

200 most important genes:

  gene name fitness t score description  
Rru_A2989 -6.1 -4.9 Precorrin-3B C17-methyltransferase region (NCBI) compare
Rru_A2990 -5.5 -10.7 precorrin-2 C20-methyltransferase (NCBI) compare
Rru_A0394 -5.5 -4.3 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A2987 -5.4 -4.7 hypothetical protein (NCBI) compare
Rru_A0668 -5.0 -2.9 Cobalamin-5-phosphate synthase CobS (NCBI) compare
Rru_A0574 -4.9 -1.8 Carboxylyase-related protein (NCBI) compare
Rru_A0334 -4.9 -4.7 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A0670 -4.8 -2.5 Cobalbumin biosynthesis enzyme (NCBI) compare
Rru_A1775 -4.7 -2.6 chromosome segregation and condensation protein ScpA (NCBI) compare
Rru_A1894 -4.6 -5.7 heavy metal translocating P-type ATPase (NCBI) compare
Rru_A1895 -4.6 -1.7 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A1190 -4.6 -1.5 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A1191 -4.4 -12.5 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A0232 -4.4 -6.2 hypothetical protein (NCBI) compare
Rru_A3190 -4.3 -2.8 Aspartate carbamoyltransferase (NCBI) compare
Rru_A2981 -4.3 -5.9 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide (NCBI) compare
Rru_A1105 -4.2 -7.0 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A2421 -4.2 -7.6 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A2983 -4.2 -0.9 Polyprenyl synthetase (NCBI) compare
Rru_A2988 -4.0 -2.9 Precorrin-6X reductase (NCBI) compare
Rru_A1837 -4.0 -4.5 Porphobilinogen synthase (NCBI) compare
Rru_A0291 -3.9 -2.5 hypothetical protein (NCBI) compare
Rru_A3558 -3.9 -1.7 Protein of unknown function UPF0005 (NCBI) compare
Rru_A0493 -3.9 -10.4 Phytoene desaturase (NCBI) compare
Rru_A3162 -3.8 -12.9 Prephenate dehydratase (NCBI) compare
Rru_A0617 -3.7 -4.1 Photosynthetic reaction center, H-chain (NCBI) compare
Rru_A0486 -3.7 -7.1 von Willebrand factor, type A (NCBI) compare
Rru_A1189 -3.7 -12.3 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A1928 -3.6 -12.2 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A2100 -3.6 -5.6 Protein of unknown function DUF81 (NCBI) compare
Rru_A1691 -3.6 -7.7 Spermine synthase (NCBI) compare
Rru_A3751 -3.6 -11.6 Argininosuccinate synthase (NCBI) compare
Rru_A0686 -3.6 -1.4 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A0627 -3.6 -9.6 Bacteriochlorophyll/chlorophyll synthetase (NCBI) compare
Rru_A3384 -3.6 -5.0 Precorrin-4 C11-methyltransferase region (NCBI) compare
Rru_A3191 -3.6 -10.6 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2886 -3.5 -22.4 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A0155 -3.5 -3.8 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A0494 -3.4 -5.5 Squalene/phytoene synthase (NCBI) compare
Rru_A3341 -3.3 -2.1 Acetylglutamate kinase (NCBI) compare
Rru_A3382 -3.3 -7.2 Cobalamin biosynthesis protein CbiB (NCBI) compare
Rru_A1085 -3.3 -1.9 Metallophosphoesterase (NCBI) compare
Rru_A0620 -3.2 -6.0 Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein (NCBI) compare
Rru_A0596 -3.2 -4.4 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A3359 -3.2 -7.1 Cobyrinic acid a,c-diamide synthase CbiA (NCBI) compare
Rru_A0514 -3.2 -9.8 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A3214 -3.1 -10.9 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A3533 -3.1 -6.6 hypothetical protein (NCBI) compare
Rru_A2978 -3.1 -8.5 Chlorophyllide reductase subunit Z (NCBI) compare
Rru_A0397 -3.1 -3.8 Argininosuccinate lyase (NCBI) compare
Rru_A1620 -3.0 -0.8 hypothetical protein (NCBI) compare
Rru_A1021 -3.0 -1.4 Sigma 32 (RpoH) (NCBI) compare
Rru_A3502 -3.0 -0.7 hypothetical protein (NCBI) compare
Rru_A2902 -3.0 -0.8 hypothetical protein (NCBI) compare
Rru_A2936 -2.9 -10.3 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2507 -2.9 -13.0 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A0622 -2.9 -9.5 Light-independent protochlorophyllide reductase, B subunit (NCBI) compare
Rru_A1890 -2.8 -2.1 hypothetical protein (NCBI) compare
Rru_A0485 -2.8 -5.1 Magnesium chelatase ATPase subunit I (NCBI) compare
Rru_A3550 -2.8 -6.0 Cobyric acid synthase CobQ (NCBI) compare
Rru_A2400 -2.7 -10.3 Ribulose-bisphosphate carboxylase, form II (NCBI) compare
Rru_A2510 -2.7 -2.0 hypothetical protein (NCBI) compare
Rru_A0621 -2.7 -12.4 Magnesium-chelatase, subunit H (NCBI) compare
Rru_A3594 -2.7 -2.6 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A2975 -2.6 -11.6 Photosynthetic reaction centre protein L subunit (NCBI) compare
Rru_A2986 -2.6 -5.7 Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI) compare
Rru_A3549 -2.6 -6.0 Cobyric acid synthase CobQ (NCBI) compare
Rru_A0100 -2.6 -0.8 hypothetical protein (NCBI) compare
Rru_A0613 -2.6 -4.1 Bacteriochlorophyll 4-vinyl reductase (NCBI) compare
Rru_A0469 -2.6 -9.5 Ketol-acid reductoisomerase (NCBI) compare
Rru_A2403 -2.6 -10.8 Inositol phosphatase/fructose-1,6-bisphosphatase (NCBI) compare
Rru_A3277 -2.6 -3.2 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A2974 -2.6 -7.1 Photosynthetic reaction centre M subunit (NCBI) compare
Rru_A1239 -2.5 -1.0 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A0752 -2.5 -1.5 hypothetical protein (NCBI) compare
Rru_A3276 -2.5 -4.0 Ornithine carbamoyltransferase (NCBI) compare
Rru_A2404 -2.5 -10.0 Phosphoribulokinase (NCBI) compare
Rru_A3227 -2.5 -6.9 conserved hypothetical protein, potential methyltransferase (NCBI) compare
Rru_A2979 -2.5 -5.6 Chlorophyllide reductase subunit Y (NCBI) compare
Rru_A3428 -2.5 -10.0 Tryptophan synthase (NCBI) compare
Rru_A3266 -2.5 -8.9 Homoserine O-acetyltransferase (NCBI) compare
Rru_A3548 -2.5 -7.7 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A1786 -2.4 -14.0 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A1218 -2.4 -1.9 phage shock protein A, PspA (NCBI) compare
Rru_A0876 -2.4 -0.9 hypothetical protein (NCBI) compare
Rru_A1552 -2.4 -2.4 Peptidase S16, ATP-dependent protease La (NCBI) compare
Rru_A0619 -2.4 -1.4 Magnesium protoporphyrin O-methyltransferase (NCBI) compare
Rru_A3427 -2.4 -13.8 Tryptophan synthase, beta chain (NCBI) compare
Rru_A2847 -2.4 -0.9 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A2952 -2.4 -2.2 Methyltransferase small (NCBI) compare
Rru_A1051 -2.3 -2.6 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A1841 -2.3 -1.6 Flavin reductase-like, FMN-binding (NCBI) compare
Rru_A2885 -2.3 -8.4 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A2992 -2.3 -2.4 Precorrin-6Y C5,15-methyltransferase (decarboxylating) (NCBI) compare
Rru_A1675 -2.3 -7.8 Cytochrome c assembly protein (NCBI) compare
Rru_A0700 -2.3 -0.9 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A0341 -2.2 -2.1 hypothetical protein (NCBI) compare
Rru_A2057 -2.2 -1.2 Molybdopterin-guanine dinucleotide biosynthesis MobB region (NCBI) compare
Rru_A3425 -2.2 -6.0 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A1112 -2.2 -0.9 hypothetical protein (NCBI) compare
Rru_A0137 -2.2 -4.9 TRAP transporter solute receptor, TAXI family (NCBI) compare
Rru_A3626 -2.2 -1.7 Glucose inhibited division protein (NCBI) compare
Rru_A2980 -2.1 -6.5 Chlorophyllide reductase iron protein subunit X (NCBI) compare
Rru_A2935 -2.1 -3.7 PAS/PAC Sensor Hybrid Histidine Kinase (NCBI) compare
Rru_A0624 -2.1 -7.4 2-vinyl bacteriochlorophyllide hydratase (NCBI) compare
Rru_A2772 -2.1 -1.7 ATP phosphoribosyltransferase (NCBI) compare
Rru_A2525 -2.1 -9.3 Peptidase U32 (NCBI) compare
Rru_A1897 -2.1 -4.1 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A0404 -2.1 -15.2 Amidophosphoribosyl transferase (NCBI) compare
Rru_A3537 -2.1 -1.2 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A3267 -2.0 -5.0 Methionine biosynthesis MetW (NCBI) compare
Rru_A0654 -2.0 -3.1 Multiple antibiotic resistance (MarC)-related proteins (NCBI) compare
Rru_A1530 -2.0 -10.3 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A0618 -2.0 -7.9 PUCC protein (NCBI) compare
Rru_A2167 -1.9 -3.8 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A0467 -1.9 -9.8 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A2524 -1.9 -8.0 Peptidase U32 (NCBI) compare
Rru_A2760 -1.9 -0.5 hypothetical protein (NCBI) compare
Rru_A1827 -1.9 -8.1 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A1692 -1.8 -3.4 S-adenosylmethionine decarboxylase related (NCBI) compare
Rru_A0644 -1.8 -1.2 hypothetical protein (NCBI) compare
Rru_A2182 -1.8 -1.5 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A2894 -1.8 -2.3 ABC transporter component (NCBI) compare
Rru_A3369 -1.8 -1.6 hypothetical protein (NCBI) compare
Rru_A3599 -1.8 -1.4 20S proteasome, A and B subunits (NCBI) compare
Rru_A3424 -1.8 -2.1 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A2512 -1.8 -4.4 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A2363 -1.8 -5.0 Endonuclease/exonuclease/phosphatase (NCBI) compare
Rru_A1896 -1.7 -5.7 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A3285 -1.7 -1.8 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A3397 -1.7 -1.9 hypothetical protein (NCBI) compare
Rru_A2181 -1.7 -8.3 NAD(P) transhydrogenase, beta subunit (NCBI) compare
Rru_A3393 -1.7 -2.1 Penicillin-binding protein 1A (NCBI) compare
Rru_A3264 -1.7 -5.7 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A1015 -1.6 -1.8 Binding-protein-dependent transport systems inner membrane component (NCBI) compare
Rru_A0671 -1.5 -3.4 cobalamin synthesis CobW protein (NCBI) compare
Rru_A0159 -1.5 -1.4 Exodeoxyribonuclease VII (NCBI) compare
Rru_A1417 -1.5 -3.3 thioredoxin-disulfide reductase (NCBI) compare
Rru_A0468 -1.5 -3.5 Acetolactate synthase, small subunit (NCBI) compare
Rru_A2656 -1.5 -1.0 ATP12 ATPase (NCBI) compare
Rru_A3705 -1.5 -1.1 Cell divisionFtsK/SpoIIIE (NCBI) compare
Rru_A3476 -1.5 -1.9 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A1179 -1.5 -0.9 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A0683 -1.5 -0.4 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A1327 -1.5 -2.7 hypothetical protein (NCBI) compare
Rru_A1804 -1.4 -3.3 N-acetyltransferase (NCBI) compare
Rru_A1683 -1.4 -4.0 HAD-superfamily hydrolase, subfamily IA, variant 1 (NCBI) compare
Rru_A3783 -1.4 -4.2 tRNA pseudouridine synthase B (NCBI) compare
Rru_A1543 -1.4 -2.1 Putative molybdenum utilization protein ModD (NCBI) compare
Rru_A1999 -1.4 -1.7 hypothetical protein (NCBI) compare
Rru_A2399 -1.4 -3.6 conserved hypothetical protein VC1941 (NCBI) compare
Rru_A2500 -1.4 -1.9 Rhodanese-like (NCBI) compare
Rru_A2183 -1.4 -4.0 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A0643 -1.4 -2.8 Protein of unknown function DUF152 (NCBI) compare
Rru_A1432 -1.4 -6.0 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A2482 -1.4 -1.7 transcription regulator containing helix turn helix domain (NCBI) compare
Rru_A3329 -1.4 -2.7 hypothetical protein (NCBI) compare
Rru_A0454 -1.3 -1.8 Leucyl aminopeptidase (NCBI) compare
Rru_A2401 -1.3 -3.4 RuBisCO transcriptional regulator cbbR, LysR family (NCBI) compare
Rru_A3380 -1.3 -1.4 hypothetical protein (NCBI) compare
Rru_B0050 -1.3 -2.3 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A2257 -1.3 -4.5 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A0399 -1.3 -0.5 Phosphoesterase, PA-phosphatase related (NCBI) compare
Rru_A2268 -1.3 -1.8 Nitrogen fixation protein NifW (NCBI) compare
Rru_A3009 -1.3 -1.9 Aminotransferase class-III (NCBI) compare
Rru_A3165 -1.3 -3.6 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A1677 -1.2 -2.7 Signal transduction histidine kinase, nitrogen specific, NtrB (NCBI) compare
Rru_A0525 -1.2 -3.2 Two component Transcriptional regulator, Winged helix family (NCBI) compare
Rru_A3221 -1.2 -0.8 hypothetical protein (NCBI) compare
Rru_A1308 -1.2 -6.9 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A0075 -1.2 -1.6 RNA-binding S4 (NCBI) compare
Rru_A1319 -1.2 -1.3 Triphosphoribosyl-dephospho-CoA synthase (NCBI) compare
Rru_A3322 -1.2 -2.0 Transcriptional Regulator, Crp/Fnr family (NCBI) compare
Rru_A0371 -1.2 -2.9 Double-transmembrane region-like (NCBI) compare
Rru_A2771 -1.2 -2.4 Histidinol dehydrogenase (NCBI) compare
Rru_A1286 -1.2 -0.5 hypothetical protein (NCBI) compare
Rru_B0049 -1.2 -1.2 dTDP-4-dehydrorhamnose reductase (NCBI) compare
Rru_A3752 -1.1 -1.3 Protein of unknown function DUF302 (NCBI) compare
Rru_A3208 -1.1 -2.5 Protein of unknown function DUF29 (NCBI) compare
Rru_A2031 -1.1 -3.6 Protein of unknown function UPF0075 (NCBI) compare
Rru_A3399 -1.1 -2.3 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A1366 -1.1 -0.8 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A0337 -1.1 -2.0 Predicted transcriptional regulator (NCBI) compare
Rru_A0625 -1.1 -1.7 hypothetical protein (NCBI) compare
Rru_A2260 -1.1 -1.4 hypothetical protein (NCBI) compare
Rru_A0421 -1.1 -2.1 hypothetical protein (NCBI) compare
Rru_A3770 -1.1 -2.6 tRNA-i(6)A37 modification enzyme MiaB (NCBI) compare
Rru_A1433 -1.1 -2.7 L-aspartate oxidase (NCBI) compare
Rru_A3800 -1.1 -0.9 hypothetical protein (NCBI) compare
Rru_A2651 -1.1 -2.6 Aminotransferase, class I and II (NCBI) compare
Rru_A2164 -1.1 -3.2 Protein of unknown function UPF0118 (NCBI) compare
Rru_A2416 -1.0 -0.8 hypothetical protein (NCBI) compare
Rru_A2001 -1.0 -4.7 hypothetical protein (NCBI) compare
Rru_A1798 -1.0 -3.6 Type I secretion outer membrane protein, TolC (NCBI) compare
Rru_A3547 -1.0 -2.4 hypothetical protein (NCBI) compare
Rru_A3614 -1.0 -2.5 Maf-like protein (NCBI) compare
Rru_A0753 -1.0 -3.7 Chaperone clpB (NCBI) compare
Rru_A0637 -1.0 -1.3 hypothetical protein (NCBI) compare
Rru_A1849 -1.0 -1.3 Recombination protein O, RecO (NCBI) compare
Rru_A1572 -1.0 -1.3 Glyoxalase/bleomycin resistance protein/dioxygenase (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Succinic Acid across organisms