Experiment set3IT012 for Rhodospirillum rubrum S1H

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Succinic Acid 31.25 mM; anaerobic

200 most important genes:

  gene name fitness t score description  
Rru_A3341 -6.4 -3.1 Acetylglutamate kinase (NCBI) compare
Rru_A2772 -6.1 -3.0 ATP phosphoribosyltransferase (NCBI) compare
Rru_A0619 -4.5 -2.6 Magnesium protoporphyrin O-methyltransferase (NCBI) compare
Rru_A3190 -4.3 -3.3 Aspartate carbamoyltransferase (NCBI) compare
Rru_A0370 -4.2 -2.9 Protein of unknown function DUF58 (NCBI) compare
Rru_A2983 -4.1 -1.3 Polyprenyl synthetase (NCBI) compare
Rru_A3162 -4.0 -14.8 Prephenate dehydratase (NCBI) compare
Rru_A1239 -4.0 -1.7 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A0394 -3.9 -5.4 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A0574 -3.8 -2.4 Carboxylyase-related protein (NCBI) compare
Rru_A2847 -3.7 -1.2 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A0397 -3.7 -7.8 Argininosuccinate lyase (NCBI) compare
Rru_A1928 -3.7 -13.8 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A1894 -3.7 -6.5 heavy metal translocating P-type ATPase (NCBI) compare
Rru_A0486 -3.6 -8.9 von Willebrand factor, type A (NCBI) compare
Rru_B0049 -3.5 -1.5 dTDP-4-dehydrorhamnose reductase (NCBI) compare
Rru_A0596 -3.5 -4.5 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A1895 -3.4 -2.3 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A2989 -3.4 -5.5 Precorrin-3B C17-methyltransferase region (NCBI) compare
Rru_A3384 -3.4 -4.5 Precorrin-4 C11-methyltransferase region (NCBI) compare
Rru_A0621 -3.3 -15.0 Magnesium-chelatase, subunit H (NCBI) compare
Rru_A2986 -3.3 -6.2 Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI) compare
Rru_A2886 -3.3 -19.4 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A3751 -3.3 -11.0 Argininosuccinate synthase (NCBI) compare
Rru_A3214 -3.3 -8.7 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A3191 -3.2 -12.3 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A1890 -3.2 -2.8 hypothetical protein (NCBI) compare
Rru_A0620 -3.2 -6.4 Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein (NCBI) compare
Rru_A1827 -3.2 -10.7 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A1189 -3.2 -10.7 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A0514 -3.2 -8.9 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A2981 -3.1 -5.3 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide (NCBI) compare
Rru_A3558 -3.1 -2.2 Protein of unknown function UPF0005 (NCBI) compare
Rru_A2979 -3.1 -4.9 Chlorophyllide reductase subunit Y (NCBI) compare
Rru_A2988 -3.0 -2.6 Precorrin-6X reductase (NCBI) compare
Rru_A2507 -3.0 -12.9 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A0622 -3.0 -8.7 Light-independent protochlorophyllide reductase, B subunit (NCBI) compare
Rru_A0493 -3.0 -10.3 Phytoene desaturase (NCBI) compare
Rru_A2974 -2.8 -10.8 Photosynthetic reaction centre M subunit (NCBI) compare
Rru_A2510 -2.8 -1.7 hypothetical protein (NCBI) compare
Rru_A0613 -2.8 -6.4 Bacteriochlorophyll 4-vinyl reductase (NCBI) compare
Rru_A1896 -2.7 -10.5 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A0627 -2.7 -7.0 Bacteriochlorophyll/chlorophyll synthetase (NCBI) compare
Rru_A2512 -2.7 -4.9 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A2936 -2.7 -10.3 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A3266 -2.7 -9.0 Homoserine O-acetyltransferase (NCBI) compare
Rru_A2100 -2.7 -6.3 Protein of unknown function DUF81 (NCBI) compare
Rru_A3428 -2.7 -10.7 Tryptophan synthase (NCBI) compare
Rru_A0624 -2.7 -6.4 2-vinyl bacteriochlorophyllide hydratase (NCBI) compare
Rru_A2421 -2.7 -6.6 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A1786 -2.6 -15.0 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A1837 -2.6 -3.2 Porphobilinogen synthase (NCBI) compare
Rru_A3264 -2.6 -7.4 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A1191 -2.6 -11.5 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A3276 -2.6 -4.4 Ornithine carbamoyltransferase (NCBI) compare
Rru_A2403 -2.5 -12.5 Inositol phosphatase/fructose-1,6-bisphosphatase (NCBI) compare
Rru_A0485 -2.5 -5.3 Magnesium chelatase ATPase subunit I (NCBI) compare
Rru_A2975 -2.5 -11.2 Photosynthetic reaction centre protein L subunit (NCBI) compare
Rru_A2370 -2.5 -2.3 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A3285 -2.5 -2.5 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A2987 -2.5 -3.8 hypothetical protein (NCBI) compare
Rru_A2182 -2.5 -2.3 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A0404 -2.5 -18.7 Amidophosphoribosyl transferase (NCBI) compare
Rru_A3267 -2.5 -6.2 Methionine biosynthesis MetW (NCBI) compare
Rru_A3548 -2.4 -10.8 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A2885 -2.4 -8.5 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A2167 -2.4 -6.3 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A3594 -2.4 -3.7 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A3227 -2.3 -8.7 conserved hypothetical protein, potential methyltransferase (NCBI) compare
Rru_A1530 -2.3 -11.6 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A0469 -2.3 -9.8 Ketol-acid reductoisomerase (NCBI) compare
Rru_A2978 -2.3 -5.9 Chlorophyllide reductase subunit Z (NCBI) compare
Rru_A0668 -2.3 -3.2 Cobalamin-5-phosphate synthase CobS (NCBI) compare
Rru_A2980 -2.3 -8.7 Chlorophyllide reductase iron protein subunit X (NCBI) compare
Rru_A0467 -2.3 -10.8 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A0296 -2.2 -1.9 hypothetical protein (NCBI) compare
Rru_A2990 -2.2 -5.4 precorrin-2 C20-methyltransferase (NCBI) compare
Rru_A1897 -2.2 -4.4 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A3382 -2.2 -5.6 Cobalamin biosynthesis protein CbiB (NCBI) compare
Rru_A1105 -2.2 -4.6 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A3359 -2.2 -6.6 Cobyrinic acid a,c-diamide synthase CbiA (NCBI) compare
Rru_A1552 -2.2 -2.3 Peptidase S16, ATP-dependent protease La (NCBI) compare
Rru_A3425 -2.2 -6.0 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A3427 -2.2 -12.1 Tryptophan synthase, beta chain (NCBI) compare
Rru_A1021 -2.2 -2.3 Sigma 32 (RpoH) (NCBI) compare
Rru_A2400 -2.1 -10.1 Ribulose-bisphosphate carboxylase, form II (NCBI) compare
Rru_A0670 -2.1 -1.3 Cobalbumin biosynthesis enzyme (NCBI) compare
Rru_A2992 -2.0 -2.2 Precorrin-6Y C5,15-methyltransferase (decarboxylating) (NCBI) compare
Rru_A0291 -2.0 -2.8 hypothetical protein (NCBI) compare
Rru_A0468 -2.0 -4.6 Acetolactate synthase, small subunit (NCBI) compare
Rru_A2524 -2.0 -8.3 Peptidase U32 (NCBI) compare
Rru_A2404 -2.0 -6.7 Phosphoribulokinase (NCBI) compare
Rru_A1691 -2.0 -5.8 Spermine synthase (NCBI) compare
Rru_A0494 -2.0 -3.9 Squalene/phytoene synthase (NCBI) compare
Rru_A0625 -1.9 -2.4 hypothetical protein (NCBI) compare
Rru_A3550 -1.9 -4.8 Cobyric acid synthase CobQ (NCBI) compare
Rru_A3397 -1.9 -2.2 hypothetical protein (NCBI) compare
Rru_A2181 -1.9 -8.6 NAD(P) transhydrogenase, beta subunit (NCBI) compare
Rru_A1286 -1.8 -0.8 hypothetical protein (NCBI) compare
Rru_A1190 -1.8 -1.2 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A3549 -1.8 -7.1 Cobyric acid synthase CobQ (NCBI) compare
Rru_A3165 -1.8 -4.3 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A2525 -1.7 -7.5 Peptidase U32 (NCBI) compare
Rru_A3277 -1.7 -2.8 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A1620 -1.7 -1.1 hypothetical protein (NCBI) compare
Rru_A2004 -1.7 -1.9 Transcriptional Regulator, LysR family (NCBI) compare
Rru_A2363 -1.7 -5.8 Endonuclease/exonuclease/phosphatase (NCBI) compare
Rru_A0159 -1.7 -1.7 Exodeoxyribonuclease VII (NCBI) compare
Rru_A0644 -1.7 -1.6 hypothetical protein (NCBI) compare
Rru_A1675 -1.7 -7.1 Cytochrome c assembly protein (NCBI) compare
Rru_A1804 -1.6 -4.3 N-acetyltransferase (NCBI) compare
Rru_A0021 -1.6 -1.5 Transcriptional Regulator, MarR family (NCBI) compare
Rru_A0372 -1.6 -5.4 hypothetical protein (NCBI) compare
Rru_A2549 -1.6 -3.8 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A0637 -1.6 -1.5 hypothetical protein (NCBI) compare
Rru_A3533 -1.5 -4.2 hypothetical protein (NCBI) compare
Rru_A2268 -1.5 -2.4 Nitrogen fixation protein NifW (NCBI) compare
Rru_A1775 -1.5 -1.3 chromosome segregation and condensation protein ScpA (NCBI) compare
Rru_A0617 -1.5 -2.6 Photosynthetic reaction center, H-chain (NCBI) compare
Rru_A0618 -1.4 -5.6 PUCC protein (NCBI) compare
Rru_A3424 -1.4 -1.6 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A1937 -1.4 -1.2 hypothetical protein (NCBI) compare
Rru_A3599 -1.4 -1.5 20S proteasome, A and B subunits (NCBI) compare
Rru_A2183 -1.4 -6.8 NAD(P)(+) transhydrogenase (AB-specific) (NCBI) compare
Rru_A2574 -1.4 -1.2 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A1051 -1.4 -2.0 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A3581 -1.4 -2.6 Transcriptional coactivator/pterin dehydratase (NCBI) compare
Rru_A0148 -1.3 -3.0 GTP-binding protein TypA (NCBI) compare
Rru_A0399 -1.3 -0.7 Phosphoesterase, PA-phosphatase related (NCBI) compare
Rru_A2038 -1.3 -4.9 Glutamate-ammonia-ligase adenylyltransferase (NCBI) compare
Rru_A0155 -1.3 -2.0 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A3398 -1.2 -2.0 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A0412 -1.2 -2.2 hypothetical protein (NCBI) compare
Rru_A0671 -1.2 -4.0 cobalamin synthesis CobW protein (NCBI) compare
Rru_A2346 -1.2 -1.1 hypothetical protein (NCBI) compare
Rru_A2771 -1.2 -1.9 Histidinol dehydrogenase (NCBI) compare
Rru_A1432 -1.2 -5.2 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A0740 -1.1 -3.1 Protein of unknown function DUF1178 (NCBI) compare
Rru_A3547 -1.1 -2.2 hypothetical protein (NCBI) compare
Rru_A3773 -1.1 -1.6 CBS domain protein (NCBI) compare
Rru_B0013 -1.1 -1.3 hypothetical protein (NCBI) compare
Rru_A3537 -1.1 -1.1 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A2140 -1.1 -3.3 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A3748 -1.0 -2.1 hypothetical protein (NCBI) compare
Rru_A1019 -1.0 -2.3 FAD dependent oxidoreductase (NCBI) compare
Rru_A0206 -1.0 -1.1 Cobalt chelatase, pCobS small subunit (NCBI) compare
Rru_A1055 -1.0 -1.7 Protein of unknown function DUF1013 (NCBI) compare
Rru_A2308 -1.0 -3.1 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A2401 -1.0 -2.8 RuBisCO transcriptional regulator cbbR, LysR family (NCBI) compare
Rru_A0561 -1.0 -4.3 Cytochrome bd ubiquinol oxidase, subunit II (NCBI) compare
Rru_A2500 -1.0 -1.9 Rhodanese-like (NCBI) compare
Rru_A3755 -1.0 -3.3 Heat shock protein Hsp20 (NCBI) compare
Rru_A1366 -1.0 -1.9 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A3627 -1.0 -3.0 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A0654 -1.0 -3.0 Multiple antibiotic resistance (MarC)-related proteins (NCBI) compare
Rru_A3385 -1.0 -1.5 OmpA/MotB (NCBI) compare
Rru_A3399 -1.0 -3.9 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A0599 -1.0 -0.8 Phosphate ABC transporter, permease protein PstC (NCBI) compare
Rru_A1617 -1.0 -1.8 Protein of unknown function DUF1289 (NCBI) compare
Rru_A1529 -1.0 -4.1 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A0643 -1.0 -2.7 Protein of unknown function DUF152 (NCBI) compare
Rru_A3052 -1.0 -1.7 hypothetical protein (NCBI) compare
Rru_A0560 -1.0 -3.7 Cytochrome bd ubiquinol oxidase, subunit I (NCBI) compare
Rru_A1434 -1.0 -5.6 Quinolinate synthetase A (NCBI) compare
Rru_A3603 -1.0 -1.9 Protein of unknown function DUF162 (NCBI) compare
Rru_B0007 -0.9 -2.1 Glycosyl transferase, group 1 (NCBI) compare
Rru_A3164 -0.9 -1.3 hypothetical protein (NCBI) compare
Rru_A2035 -0.9 -5.3 phosphate binding protein, putative (NCBI) compare
Rru_A2062 -0.9 -2.1 hypothetical protein (NCBI) compare
Rru_A1518 -0.9 -0.9 hypothetical protein (NCBI) compare
Rru_A1433 -0.9 -2.4 L-aspartate oxidase (NCBI) compare
Rru_A2951 -0.9 -0.9 hypothetical protein (NCBI) compare
Rru_A2201 -0.9 -2.9 Peptidase S1C, Do (NCBI) compare
Rru_A0137 -0.8 -4.2 TRAP transporter solute receptor, TAXI family (NCBI) compare
Rru_A1611 -0.8 -0.9 Cobalamin synthesis protein/P47K (NCBI) compare
Rru_A1265 -0.8 -3.4 Transcriptional Regulator, DeoR family (NCBI) compare
Rru_A0424 -0.8 -0.7 hypothetical protein (NCBI) compare
Rru_A1687 -0.8 -1.1 Inositol monophosphatase (NCBI) compare
Rru_A0232 -0.8 -1.8 hypothetical protein (NCBI) compare
Rru_A2937 -0.8 -1.0 Asparagine synthase, glutamine-hydrolyzing (NCBI) compare
Rru_A3054 -0.8 -0.8 Ribonuclease H (NCBI) compare
Rru_A1218 -0.8 -1.0 phage shock protein A, PspA (NCBI) compare
Rru_A1194 -0.8 -2.0 Protein of unknown function DUF134 (NCBI) compare
Rru_A0329 -0.8 -1.4 hypothetical protein (NCBI) compare
Rru_A2002 -0.8 -1.8 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (NCBI) compare
Rru_A0628 -0.8 -2.2 PUCC protein (NCBI) compare
Rru_A2615 -0.8 -3.6 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A1168 -0.7 -2.1 Hydrogenase expression/synthesis, HypA (NCBI) compare
Rru_A0307 -0.7 -2.3 Hydrogenase expression/formation protein (HUPF/HYPC) (NCBI) compare
Rru_A3790 -0.7 -3.9 Glycolate reductase (NCBI) compare
Rru_A3208 -0.7 -2.0 Protein of unknown function DUF29 (NCBI) compare
Rru_A0389 -0.7 -1.6 Antibiotic biosynthesis monooxygenase (NCBI) compare
Rru_A2857 -0.7 -2.8 Flagellar FlbT (NCBI) compare
Rru_A1308 -0.7 -4.3 Acyl-CoA dehydrogenase (NCBI) compare
Rru_A1798 -0.7 -2.7 Type I secretion outer membrane protein, TolC (NCBI) compare
Rru_A3019 -0.7 -1.0 hypothetical protein (NCBI) compare
Rru_A0164 -0.7 -4.1 Sulfate transporter/antisigma-factor antagonist (NCBI) compare
Rru_A0874 -0.7 -2.7 hypothetical protein (NCBI) compare
Rru_A1309 -0.7 -3.6 acetoacetyl-CoA reductase (NCBI) compare
Rru_A1788 -0.7 -1.0 Response regulator receiver domain protein (CheY) (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Succinic Acid across organisms