Experiment set3IT011 for Pseudomonas fluorescens FW300-N1B4

Compare to:

LB with Doxycycline hyclate 0.0001 mg/ml

200 most important genes:

  gene name fitness t score description  
Pf1N1B4_1468 -3.8 -15.7 InaA protein compare
Pf1N1B4_1441 -3.7 -11.5 Putative esterase, FIGfam005057 compare
Pf1N1B4_2733 -3.6 -2.4 DNA polymerase III alpha subunit (EC 2.7.7.7) compare
Pf1N1B4_2106 -3.5 -2.4 Hydrogen peroxide-inducible genes activator compare
Pf1N1B4_2885 -3.5 -4.8 Paraquat-inducible protein A compare
Pf1N1B4_3751 -3.5 -2.5 FIG00953060: hypothetical protein compare
Pf1N1B4_389 -3.3 -5.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_3667 -3.3 -7.9 Nucleoside ABC transporter, periplasmic nucleoside-binding protein conserved
Pf1N1B4_289 -3.3 -16.1 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf1N1B4_3166 -3.2 -11.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_3909 -3.1 -2.8 Cell division inhibitor-related protein compare
Pf1N1B4_3785 -3.1 -2.6 FOG: Ankyrin repeat compare
Pf1N1B4_388 -3.0 -5.7 OmpA family protein compare
Pf1N1B4_1641 -3.0 -10.3 Lysine-arginine-ornithine-binding periplasmic protein precursor (TC 3.A.1.3.1) compare
Pf1N1B4_2917 -3.0 -7.8 FIG140336: TPR domain protein compare
Pf1N1B4_3833 -2.9 -8.8 Major porin and structural outer membrane porin OprF compare
Pf1N1B4_4799 -2.9 -3.7 Multidrug resistance protein B compare
Pf1N1B4_1307 -2.9 -2.0 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf1N1B4_2114 -2.9 -6.3 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf1N1B4_2886 -2.9 -12.9 Paraquat-inducible protein B compare
Pf1N1B4_3668 -2.8 -7.3 Nucleoside ABC transporter, periplasmic nucleoside-binding protein conserved
Pf1N1B4_3815 -2.7 -4.8 FIG002781: Alpha-L-glutamate ligase family protein compare
Pf1N1B4_4740 -2.7 -3.1 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf1N1B4_448 -2.7 -1.9 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf1N1B4_1469 -2.6 -12.6 Heptose kinase WapQ, eukaryotic type compare
Pf1N1B4_756 -2.6 -2.5 hypothetical protein compare
Pf1N1B4_3817 -2.6 -5.1 FIG008443: hypothetical protein compare
Pf1N1B4_4636 -2.5 -2.8 TPR domain protein in aerotolerance operon compare
Pf1N1B4_1403 -2.5 -6.6 3'-to-5' exoribonuclease RNase R compare
Pf1N1B4_1057 -2.5 -3.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf1N1B4_3093 -2.5 -1.4 Outer membrane protein H precursor compare
Pf1N1B4_3246 -2.4 -3.7 RND efflux system, inner membrane transporter CmeB compare
Pf1N1B4_1906 -2.4 -3.3 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
Pf1N1B4_1619 -2.4 -9.9 Carboxyl-terminal protease (EC 3.4.21.102) compare
Pf1N1B4_1402 -2.4 -3.4 23S rRNA (guanosine-2'-O-) -methyltransferase rlmB (EC 2.1.1.-) compare
Pf1N1B4_1153 -2.4 -3.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf1N1B4_3559 -2.4 -12.0 Aromatic amino acid transport protein AroP compare
Pf1N1B4_2609 -2.4 -12.1 Catalase (EC 1.11.1.6) compare
Pf1N1B4_2227 -2.3 -2.7 FIG019278: hypothetical protein compare
Pf1N1B4_888 -2.3 -4.8 Transglycosylase, Slt family compare
Pf1N1B4_3143 -2.3 -3.6 RecA protein compare
Pf1N1B4_2884 -2.2 -5.8 Paraquat-inducible protein A compare
Pf1N1B4_291 -2.2 -4.6 Major outer membrane lipoprotein I compare
Pf1N1B4_1617 -2.2 -7.7 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1) compare
Pf1N1B4_58 -2.2 -6.1 Transaldolase (EC 2.2.1.2) compare
Pf1N1B4_5330 -2.2 -1.4 hypothetical protein compare
Pf1N1B4_2856 -2.1 -4.0 Poly(A) polymerase (EC 2.7.7.19) compare
Pf1N1B4_1462 -2.1 -11.0 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
Pf1N1B4_1142 -2.1 -8.4 Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB compare
Pf1N1B4_2706 -2.1 -2.9 FIG00954871: hypothetical protein compare
Pf1N1B4_3091 -2.1 -3.3 Membrane-associated zinc metalloprotease compare
Pf1N1B4_980 -2.0 -2.2 hypothetical protein compare
Pf1N1B4_175 -2.0 -2.6 sigma-54 dependent transcriptional regulator compare
Pf1N1B4_1367 -2.0 -3.5 Glycine cleavage system transcriptional activator compare
Pf1N1B4_5611 -2.0 -2.8 L-carnitine dehydratase/bile acid-inducible protein F (EC 2.8.3.16) compare
Pf1N1B4_723 -2.0 -8.7 two-component system sensor protein conserved
Pf1N1B4_3973 -2.0 -3.6 ABC-type spermidine/putrescine transport system, permease component I compare
Pf1N1B4_1544 -2.0 -7.7 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-) compare
Pf1N1B4_4132 -2.0 -2.8 Mobile element protein compare
Pf1N1B4_290 -2.0 -13.9 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf1N1B4_2651 -1.9 -5.0 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) compare
Pf1N1B4_3566 -1.9 -6.7 Phenylalanine-4-hydroxylase (EC 1.14.16.1) compare
Pf1N1B4_4168 -1.9 -2.7 putative membrane protein compare
Pf1N1B4_3303 -1.9 -3.2 Urea carboxylase-related aminomethyltransferase (EC 2.1.2.10) compare
Pf1N1B4_1614 -1.9 -3.0 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf1N1B4_5498 -1.9 -2.6 hypothetical protein compare
Pf1N1B4_3147 -1.9 -7.5 Putative NADPH-quinone reductase (modulator of drug activity B) compare
Pf1N1B4_4295 -1.9 -2.2 FIG00954434: hypothetical protein compare
Pf1N1B4_4531 -1.8 -2.3 FIG01221261: hypothetical protein compare
Pf1N1B4_3745 -1.8 -3.2 Thiamin ABC transporter, transmembrane component compare
Pf1N1B4_5891 -1.8 -3.1 FIG00961753: hypothetical protein compare
Pf1N1B4_5045 -1.8 -3.9 Cytochrome oxidase biogenesis protein Sco1/SenC/PrrC, putative copper metallochaperone compare
Pf1N1B4_4882 -1.8 -3.7 Transcriptional regulator MexT compare
Pf1N1B4_1180 -1.8 -1.4 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf1N1B4_2621 -1.8 -1.7 PspA/IM30 family protein compare
Pf1N1B4_3362 -1.8 -4.0 Multidrug resistance protein B compare
Pf1N1B4_1296 -1.7 -9.1 Biosynthetic arginine decarboxylase (EC 4.1.1.19) (from data) compare
Pf1N1B4_188 -1.7 -2.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf1N1B4_2154 -1.7 -2.5 hypothetical protein compare
Pf1N1B4_3141 -1.7 -2.3 FIG00959768: hypothetical protein compare
Pf1N1B4_3582 -1.7 -1.3 C-methyltransferase compare
Pf1N1B4_5622 -1.7 -2.9 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54) compare
Pf1N1B4_3885 -1.7 -4.1 Predicted hydrolase of the alpha/beta-hydrolase fold compare
Pf1N1B4_5531 -1.7 -3.8 hypothetical protein compare
Pf1N1B4_5022 -1.7 -3.3 hypothetical protein compare
Pf1N1B4_4301 -1.7 -3.4 hypothetical protein compare
Pf1N1B4_4667 -1.7 -3.0 Acriflavin resistance plasma membrane protein compare
Pf1N1B4_4107 -1.7 -2.3 Probable glutathione S-transferase (EC 2.5.1.18), YfcF homolog compare
Pf1N1B4_4731 -1.6 -3.2 Sigma-54 dependent transcriptional regulator compare
Pf1N1B4_4417 -1.6 -2.0 Transcriptional regulator compare
Pf1N1B4_974 -1.6 -3.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf1N1B4_3373 -1.6 -3.0 FIG00954689: hypothetical protein compare
Pf1N1B4_4134 -1.6 -2.0 Na+ driven multidrug efflux pump compare
Pf1N1B4_4810 -1.6 -2.9 Polymyxin resistance protein PmrM compare
Pf1N1B4_5813 -1.6 -2.1 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) compare
Pf1N1B4_2322 -1.6 -2.7 FIG015547: peptidase, M16 family compare
Pf1N1B4_3816 -1.6 -5.2 FIG139976: hypothetical protein compare
Pf1N1B4_419 -1.6 -2.2 Transcriptional regulator, TetR family compare
Pf1N1B4_3364 -1.6 -2.8 Cyn operon transcriptional activator compare
Pf1N1B4_4957 -1.6 -1.8 Transcriptional regulator, TetR family compare
Pf1N1B4_2169 -1.5 -2.8 FIG00953808: hypothetical protein compare
Pf1N1B4_4119 -1.5 -2.1 dioxygenase compare
Pf1N1B4_3497 -1.5 -4.9 Heat shock protein compare
Pf1N1B4_5864 -1.5 -2.1 Glycolate dehydrogenase (EC 1.1.99.14), iron-sulfur subunit GlcF compare
Pf1N1B4_3605 -1.5 -1.6 Flagellar motor switch protein FliG compare
Pf1N1B4_1508 -1.5 -1.9 Lysophospholipid acyltransferase compare
Pf1N1B4_3828 -1.5 -6.2 Ribonuclease E inhibitor RraA compare
Pf1N1B4_675 -1.5 -2.8 hypothetical protein compare
Pf1N1B4_5719 -1.5 -3.0 hypothetical protein compare
Pf1N1B4_5823 -1.5 -1.3 Na(+) H(+) antiporter subunit C compare
Pf1N1B4_3627 -1.5 -1.6 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf1N1B4_1507 -1.5 -3.5 FIG143263: Glycosyl transferase compare
Pf1N1B4_1749 -1.5 -1.8 Prevent host death protein, Phd antitoxin compare
Pf1N1B4_340 -1.5 -4.7 Alpha-L-Rha alpha-1,3-L-rhamnosyltransferase (EC 2.4.1.-) compare
Pf1N1B4_13 -1.5 -1.9 SAM-dependent methyltransferase YafE (UbiE paralog) compare
Pf1N1B4_5682 -1.5 -2.2 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf1N1B4_769 -1.5 -5.1 Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) compare
Pf1N1B4_984 -1.4 -2.9 Alginate biosynthesis protein Alg44 compare
Pf1N1B4_4540 -1.4 -1.9 Uncharacterized protein ImpJ/VasE compare
Pf1N1B4_1889 -1.4 -8.7 Fused spore maturation proteins A and B compare
Pf1N1B4_4448 -1.4 -2.1 COGs COG2343 compare
Pf1N1B4_3782 -1.4 -2.3 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) compare
Pf1N1B4_4358 -1.4 -1.6 Acetyltransferase, GNAT family compare
Pf1N1B4_1615 -1.4 -2.5 Glutaredoxin 3 (Grx3) compare
Pf1N1B4_4602 -1.4 -1.9 Transcriptional regulators, LysR family compare
Pf1N1B4_4063 -1.4 -2.9 CrcB protein compare
Pf1N1B4_2491 -1.4 -3.0 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf1N1B4_2026 -1.4 -3.1 Transcriptional regulator compare
Pf1N1B4_3165 -1.4 -4.8 DNA polymerase IV (EC 2.7.7.7) compare
Pf1N1B4_2412 -1.4 -3.2 ATP-dependent 23S rRNA helicase DbpA compare
Pf1N1B4_2228 -1.4 -3.1 FIG001590: Putative conserved exported protein precursor compare
Pf1N1B4_4001 -1.4 -2.3 Membrane fusion component of tripartite multidrug resistance system compare
Pf1N1B4_4860 -1.4 -2.3 Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-) compare
Pf1N1B4_4024 -1.4 -2.2 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf1N1B4_115 -1.4 -1.5 Membrane protein mosC compare
Pf1N1B4_4833 -1.4 -2.7 DNA-binding response regulator, LuxR family compare
Pf1N1B4_5476 -1.3 -1.6 hypothetical protein compare
Pf1N1B4_32 -1.3 -2.7 Transcriptional regulator, TetR family compare
Pf1N1B4_69 -1.3 -2.1 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf1N1B4_3234 -1.3 -2.2 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf1N1B4_3939 -1.3 -2.5 FIG00953489: hypothetical protein compare
Pf1N1B4_1891 -1.3 -1.6 ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C compare
Pf1N1B4_3831 -1.3 -5.1 CmpX compare
Pf1N1B4_1501 -1.3 -3.8 3-oxoacyl-[ACP] synthase compare
Pf1N1B4_2296 -1.3 -2.8 FIG00350678: hypothetical protein compare
Pf1N1B4_3742 -1.3 -1.7 Oxidoreductase, zinc-binding compare
Pf1N1B4_431 -1.3 -4.1 hypothetical protein compare
Pf1N1B4_2105 -1.3 -2.2 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf1N1B4_5446 -1.3 -2.9 hypothetical protein compare
Pf1N1B4_1310 -1.3 -3.6 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf1N1B4_5383 -1.3 -7.1 hypothetical protein compare
Pf1N1B4_4974 -1.3 -2.3 Protease subunit of ATP-dependent Clp proteases compare
Pf1N1B4_1128 -1.3 -2.1 hypothetical protein compare
Pf1N1B4_617 -1.3 -1.6 Carbamate kinase (EC 2.7.2.2) compare
Pf1N1B4_4748 -1.3 -2.9 transporter, putative compare
Pf1N1B4_2085 -1.3 -2.0 Uncharacterized protein similar to VCA0109 compare
Pf1N1B4_3212 -1.3 -2.2 hypothetical protein compare
Pf1N1B4_3498 -1.3 -1.7 FIG00953240: hypothetical protein compare
Pf1N1B4_3483 -1.2 -3.4 Transcriptional regulatory protein PhoP compare
Pf1N1B4_2458 -1.2 -2.0 Sarcosine oxidase gamma subunit (EC 1.5.3.1) compare
Pf1N1B4_2485 -1.2 -1.7 Competence protein F homolog, phosphoribosyltransferase domain; protein YhgH required for utilization of DNA as sole source of carbon and energy compare
Pf1N1B4_4828 -1.2 -3.1 hypothetical protein compare
Pf1N1B4_1847 -1.2 -3.0 hypothetical protein compare
Pf1N1B4_5340 -1.2 -2.5 hypothetical protein compare
Pf1N1B4_3361 -1.2 -6.8 Outer membrane receptor proteins, likely involved in siderophore uptake @ TonB-dependent siderophore receptor compare
Pf1N1B4_5607 -1.2 -2.0 C4-dicarboxylate transport protein compare
Pf1N1B4_2021 -1.2 -1.3 hypothetical protein compare
Pf1N1B4_483 -1.2 -2.1 Metal-dependent hydrolase related to alanyl-tRNA synthetase compare
Pf1N1B4_2299 -1.2 -1.8 probable integral membrane protein NMA1899 compare
Pf1N1B4_5753 -1.2 -1.9 putative membrane protein compare
Pf1N1B4_5774 -1.2 -2.5 Nitrite reductase associated c-type cytochorome NirN compare
Pf1N1B4_3113 -1.2 -6.7 Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) compare
Pf1N1B4_3372 -1.2 -1.6 FIG00962464: hypothetical protein compare
Pf1N1B4_5348 -1.2 -1.9 hypothetical protein compare
Pf1N1B4_2436 -1.1 -3.2 FIG00953563: hypothetical protein compare
Pf1N1B4_3855 -1.1 -2.2 Chromosome partition protein smc compare
Pf1N1B4_824 -1.1 -2.7 POSSIBLE MEMBRANE PROTEIN compare
Pf1N1B4_1620 -1.1 -3.3 Putative periplasmic protein YibQ, distant homology with nucleoside diphosphatase and polysaccharide deacetylase compare
Pf1N1B4_936 -1.1 -4.5 GGDEF domain protein compare
Pf1N1B4_3375 -1.1 -7.4 Fe(2+)/alpha-ketoglutarate-dependent dioxygenase LpxO compare
Pf1N1B4_4418 -1.1 -1.6 hypothetical protein compare
Pf1N1B4_4949 -1.1 -2.5 Formate dehydrogenase N gamma subunit (EC 1.2.1.2) compare
Pf1N1B4_3129 -1.1 -1.4 Prophage baseplate assembly protein V compare
Pf1N1B4_95 -1.1 -3.1 contains type I hydrophobic transmembrane region and ATP/GTP binding motif compare
Pf1N1B4_1509 -1.1 -5.3 Putative histidine ammonia-lyase protein compare
Pf1N1B4_4243 -1.1 -3.0 Alcohol dehydrogenase (EC 1.1.1.1) compare
Pf1N1B4_1235 -1.1 -4.4 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf1N1B4_1837 -1.1 -1.0 Osmotically inducible protein C compare
Pf1N1B4_1247 -1.1 -2.5 transcriptional regulator, MerR family compare
Pf1N1B4_1236 -1.1 -4.4 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf1N1B4_384 -1.1 -1.4 proteinase inhibitor compare
Pf1N1B4_336 -1.1 -7.7 Teichoic acid export ATP-binding protein TagH (EC 3.6.3.40) compare
Pf1N1B4_3818 -1.1 -1.3 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf1N1B4_2071 -1.1 -1.6 Protein phosphatase ImpM compare
Pf1N1B4_765 -1.1 -1.7 Cys-tRNA(Pro) deacylase YbaK compare
Pf1N1B4_2435 -1.1 -1.8 hypothetical protein compare
Pf1N1B4_1220 -1.1 -3.7 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) compare
Pf1N1B4_2176 -1.1 -2.3 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf1N1B4_1011 -1.1 -3.1 ribosomal subunit interface protein, putative compare
Pf1N1B4_1675 -1.1 -1.9 Transcriptional regulator compare


Specific Phenotypes

For 23 genes in this experiment

For stress Doxycycline hyclate in Pseudomonas fluorescens FW300-N1B4

For stress Doxycycline hyclate across organisms