Experiment set3IT011 for Rhodospirillum rubrum S1H

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Succinic Acid 31.25 mM; anaerobic

200 most important genes:

  gene name fitness t score description  
Rru_A1190 -5.3 -1.4 3-isopropylmalate dehydratase small subunit region (NCBI) compare
Rru_A1837 -4.0 -4.5 Porphobilinogen synthase (NCBI) compare
Rru_A2983 -3.9 -1.1 Polyprenyl synthetase (NCBI) compare
Rru_A1239 -3.9 -1.5 Glutamate 5-kinase, ProB-related (NCBI) compare
Rru_A0596 -3.7 -4.6 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype (NCBI) compare
Rru_A3594 -3.6 -3.6 Histidine biosynthesis protein HisF (NCBI) compare
Rru_A2847 -3.6 -1.0 Transcriptional regulators, TraR/DksA family (NCBI) compare
Rru_A3264 -3.6 -9.8 Histidinol-phosphate aminotransferase (NCBI) compare
Rru_A0963 -3.4 -2.6 MifU-like protein, Fe-S cluster formation (NCBI) compare
Rru_A1827 -3.4 -12.5 Glycine hydroxymethyltransferase (NCBI) compare
Rru_A0058 -3.4 -0.9 Dihydrokaempferol 4-reductase (NCBI) compare
Rru_A1894 -3.3 -5.2 heavy metal translocating P-type ATPase (NCBI) compare
Rru_A3190 -3.3 -2.7 Aspartate carbamoyltransferase (NCBI) compare
Rru_A1928 -3.2 -13.5 Yeast 2-isopropylmalate synthase (NCBI) compare
Rru_A0574 -3.0 -2.2 Carboxylyase-related protein (NCBI) compare
Rru_A0397 -2.9 -6.9 Argininosuccinate lyase (NCBI) compare
Rru_A1620 -2.9 -0.9 hypothetical protein (NCBI) compare
Rru_A1021 -2.9 -1.6 Sigma 32 (RpoH) (NCBI) compare
Rru_A1189 -2.9 -12.6 3-isopropylmalate dehydratase large subunit region (NCBI) compare
Rru_A3162 -2.9 -13.1 Prephenate dehydratase (NCBI) compare
Rru_A0514 -2.9 -7.9 Dihydroorotate dehydrogenase 2 (NCBI) compare
Rru_A3214 -2.8 -10.8 O-succinylhomoserine sulfhydrylase (NCBI) compare
Rru_A2507 -2.8 -12.9 Orotate phosphoribosyl transferase (NCBI) compare
Rru_A1775 -2.8 -2.5 chromosome segregation and condensation protein ScpA (NCBI) compare
Rru_A2936 -2.8 -10.8 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2902 -2.8 -0.9 hypothetical protein (NCBI) compare
Rru_A2886 -2.7 -17.9 Carbamoyl-phosphate synthase, large subunit, glutamine-dependent (NCBI) compare
Rru_A2421 -2.7 -6.1 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) compare
Rru_A2981 -2.6 -4.4 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide (NCBI) compare
Rru_A1895 -2.6 -1.9 Glutamine amidotransferase of anthranilate synthase (NCBI) compare
Rru_A1191 -2.6 -12.7 3-isopropylmalate dehydrogenase (NCBI) compare
Rru_A3751 -2.6 -10.0 Argininosuccinate synthase (NCBI) compare
Rru_A3548 -2.5 -10.3 Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase (NCBI) compare
Rru_A1786 -2.5 -15.0 Dihydroxy-acid dehydratase (NCBI) compare
Rru_A3428 -2.5 -13.0 Tryptophan synthase (NCBI) compare
Rru_A3227 -2.5 -7.7 conserved hypothetical protein, potential methyltransferase (NCBI) compare
Rru_A0617 -2.5 -4.7 Photosynthetic reaction center, H-chain (NCBI) compare
Rru_B0049 -2.5 -1.5 dTDP-4-dehydrorhamnose reductase (NCBI) compare
Rru_A2100 -2.4 -4.9 Protein of unknown function DUF81 (NCBI) compare
Rru_A1105 -2.4 -3.7 tRNA synthetase, class II (G, H, P and S) (NCBI) compare
Rru_A0621 -2.4 -12.6 Magnesium-chelatase, subunit H (NCBI) compare
Rru_A3285 -2.3 -2.6 Response regulator receiver domain protein (CheY) (NCBI) compare
Rru_A1897 -2.3 -5.3 Indole-3-glycerol-phosphate synthase (NCBI) compare
Rru_A1286 -2.3 -0.8 hypothetical protein (NCBI) compare
Rru_A2370 -2.3 -1.8 GCN5-related N-acetyltransferase (NCBI) compare
Rru_A0469 -2.3 -10.5 Ketol-acid reductoisomerase (NCBI) compare
Rru_A3191 -2.3 -8.4 Dihydroorotase multifunctional complex type (NCBI) compare
Rru_A2167 -2.3 -4.2 Phosphoribosylformylglycinamidine cyclo-ligase (NCBI) compare
Rru_A0485 -2.3 -5.3 Magnesium chelatase ATPase subunit I (NCBI) compare
Rru_A1051 -2.2 -3.1 Phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI) compare
Rru_A2403 -2.2 -10.0 Inositol phosphatase/fructose-1,6-bisphosphatase (NCBI) compare
Rru_A3425 -2.2 -8.0 Phosphoribosylanthranilate isomerase (NCBI) compare
Rru_A2980 -2.2 -7.4 Chlorophyllide reductase iron protein subunit X (NCBI) compare
Rru_A3558 -2.2 -1.3 Protein of unknown function UPF0005 (NCBI) compare
Rru_A3427 -2.1 -13.9 Tryptophan synthase, beta chain (NCBI) compare
Rru_A1530 -2.1 -11.6 5,10-methylenetetrahydrofolate reductase (NCBI) compare
Rru_A0620 -2.1 -6.2 Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein (NCBI) compare
Rru_A3165 -2.1 -4.7 Histidinol-phosphate phosphatase, putative, inositol monophosphatase (NCBI) compare
Rru_A2400 -2.1 -9.0 Ribulose-bisphosphate carboxylase, form II (NCBI) compare
Rru_A3266 -2.1 -8.4 Homoserine O-acetyltransferase (NCBI) compare
Rru_A2974 -2.1 -7.0 Photosynthetic reaction centre M subunit (NCBI) compare
Rru_A1896 -2.1 -6.6 Anthranilate phosphoribosyl transferase (NCBI) compare
Rru_A3547 -2.1 -3.4 hypothetical protein (NCBI) compare
Rru_A1890 -2.0 -1.8 hypothetical protein (NCBI) compare
Rru_A2404 -1.9 -6.9 Phosphoribulokinase (NCBI) compare
Rru_A0159 -1.9 -2.2 Exodeoxyribonuclease VII (NCBI) compare
Rru_A2525 -1.9 -7.9 Peptidase U32 (NCBI) compare
Rru_A2772 -1.9 -1.9 ATP phosphoribosyltransferase (NCBI) compare
Rru_A0622 -1.9 -5.8 Light-independent protochlorophyllide reductase, B subunit (NCBI) compare
Rru_A2524 -1.9 -7.3 Peptidase U32 (NCBI) compare
Rru_A1552 -1.9 -2.2 Peptidase S16, ATP-dependent protease La (NCBI) compare
Rru_A0394 -1.8 -3.1 Amino-acid N-acetyltransferase (NCBI) compare
Rru_A2771 -1.8 -2.5 Histidinol dehydrogenase (NCBI) compare
Rru_A3276 -1.8 -4.2 Ornithine carbamoyltransferase (NCBI) compare
Rru_A1767 -1.8 -1.6 peptidase M23B (NCBI) compare
Rru_A0404 -1.8 -12.4 Amidophosphoribosyl transferase (NCBI) compare
Rru_A1804 -1.8 -4.6 N-acetyltransferase (NCBI) compare
Rru_A0486 -1.8 -4.8 von Willebrand factor, type A (NCBI) compare
Rru_A2975 -1.8 -7.3 Photosynthetic reaction centre protein L subunit (NCBI) compare
Rru_A3267 -1.8 -4.9 Methionine biosynthesis MetW (NCBI) compare
Rru_A0627 -1.7 -5.1 Bacteriochlorophyll/chlorophyll synthetase (NCBI) compare
Rru_A2952 -1.7 -2.1 Methyltransferase small (NCBI) compare
Rru_A0618 -1.7 -7.0 PUCC protein (NCBI) compare
Rru_A3393 -1.7 -3.3 Penicillin-binding protein 1A (NCBI) compare
Rru_A0908 -1.7 -1.2 microcompartments protein (NCBI) compare
Rru_A3704 -1.7 -4.3 Periplasmic solute binding protein (NCBI) compare
Rru_A2979 -1.6 -4.1 Chlorophyllide reductase subunit Y (NCBI) compare
Rru_A0624 -1.6 -5.5 2-vinyl bacteriochlorophyllide hydratase (NCBI) compare
Rru_A3533 -1.5 -5.0 hypothetical protein (NCBI) compare
Rru_A2935 -1.5 -3.9 PAS/PAC Sensor Hybrid Histidine Kinase (NCBI) compare
Rru_A2978 -1.5 -5.9 Chlorophyllide reductase subunit Z (NCBI) compare
Rru_A1849 -1.5 -2.0 Recombination protein O, RecO (NCBI) compare
Rru_A0876 -1.5 -0.8 hypothetical protein (NCBI) compare
Rru_A3341 -1.4 -1.7 Acetylglutamate kinase (NCBI) compare
Rru_A2656 -1.4 -0.9 ATP12 ATPase (NCBI) compare
Rru_A2099 -1.4 -6.2 surface antigen (NCBI) compare
Rru_A1608 -1.4 -6.6 MscS Mechanosensitive ion channel (NCBI) compare
Rru_A2085 -1.4 -2.3 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) compare
Rru_A2512 -1.4 -3.8 3-oxoacyl-(acyl-carrier-protein) reductase (NCBI) compare
Rru_A2885 -1.4 -4.3 Carbamoyl-phosphate synthase, small subunit (NCBI) compare
Rru_A1048 -1.4 -2.1 Protein of unknown function DUF465 (NCBI) compare
Rru_A0398 -1.4 -2.6 Thiol-disulfide isomerase and thioredoxins-like (NCBI) compare
Rru_A2990 -1.4 -5.2 precorrin-2 C20-methyltransferase (NCBI) compare
Rru_A2098 -1.4 -5.0 Protein of unknown function DUF490 (NCBI) compare
Rru_A2549 -1.3 -4.2 HAD-superfamily hydrolase subfamily IIB (NCBI) compare
Rru_A3660 -1.3 -2.1 tRNA and rRNA cytosine-C5-methylase (NCBI) compare
Rru_B0050 -1.3 -1.8 dTDP-glucose 4,6-dehydratase (NCBI) compare
Rru_A1432 -1.3 -6.3 Nicotinate-nucleotide pyrophosphorylase (NCBI) compare
Rru_A0467 -1.2 -7.1 Acetolactate synthase, large subunit, biosynthetic type (NCBI) compare
Rru_A1572 -1.2 -1.7 Glyoxalase/bleomycin resistance protein/dioxygenase (NCBI) compare
Rru_A0348 -1.2 -1.4 CRISPR-associated protein, Cas2 (NCBI) compare
Rru_A0181 -1.2 -2.2 hypothetical protein (NCBI) compare
Rru_A3743 -1.2 -0.8 hypothetical protein (NCBI) compare
Rru_A1327 -1.2 -1.5 hypothetical protein (NCBI) compare
Rru_A1678 -1.2 -2.3 Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) compare
Rru_A0399 -1.2 -0.5 Phosphoesterase, PA-phosphatase related (NCBI) compare
Rru_A1348 -1.2 -2.3 Protein of unknown function DUF81 (NCBI) compare
Rru_A0224 -1.2 -2.1 Protein of unknown function DUF160 (NCBI) compare
Rru_B0005 -1.2 -0.5 Glycosyl transferase (NCBI) compare
Rru_A2992 -1.2 -1.2 Precorrin-6Y C5,15-methyltransferase (decarboxylating) (NCBI) compare
Rru_A2986 -1.2 -2.9 Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI) compare
Rru_A1950 -1.1 -0.9 Transcriptional regulator, ModE family (NCBI) compare
Rru_A3502 -1.1 -0.5 hypothetical protein (NCBI) compare
Rru_A1086 -1.1 -1.9 hypothetical protein (RefSeq) compare
Rru_A2988 -1.1 -1.6 Precorrin-6X reductase (NCBI) compare
Rru_A0329 -1.1 -1.8 hypothetical protein (NCBI) compare
Rru_A2615 -1.1 -4.6 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A2038 -1.0 -4.6 Glutamate-ammonia-ligase adenylyltransferase (NCBI) compare
Rru_A2510 -1.0 -1.2 hypothetical protein (NCBI) compare
Rru_A0668 -1.0 -1.2 Cobalamin-5-phosphate synthase CobS (NCBI) compare
Rru_A1571 -1.0 -2.7 metallo-beta-lactamase (NCBI) compare
Rru_A0619 -1.0 -0.7 Magnesium protoporphyrin O-methyltransferase (NCBI) compare
Rru_A0607 -1.0 -1.3 Adenine phosphoribosyl transferase (NCBI) compare
Rru_A1525 -1.0 -1.6 Nucleoside diphosphate pyrophosphatase (NCBI) compare
Rru_A1677 -1.0 -2.7 Signal transduction histidine kinase, nitrogen specific, NtrB (NCBI) compare
Rru_A0137 -1.0 -4.2 TRAP transporter solute receptor, TAXI family (NCBI) compare
Rru_A2363 -1.0 -3.3 Endonuclease/exonuclease/phosphatase (NCBI) compare
Rru_A1529 -1.0 -4.2 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A3539 -1.0 -3.4 GlnB (protein PII) uridylyltransferase, GlnD (NCBI) compare
Rru_A3380 -1.0 -0.8 hypothetical protein (NCBI) compare
Rru_A1758 -1.0 -1.7 hypothetical protein (NCBI) compare
Rru_A2308 -0.9 -1.7 Transcriptional Regulator, ArsR family (NCBI) compare
Rru_A2989 -0.9 -2.4 Precorrin-3B C17-methyltransferase region (NCBI) compare
Rru_A2140 -0.9 -2.4 Transcriptional Regulator, XRE family (NCBI) compare
Rru_A2198 -0.9 -1.5 Protein of unknown function UPF0066 (NCBI) compare
Rru_A3173 -0.9 -3.1 Transcriptional Regulator, TetR family (NCBI) compare
Rru_A1434 -0.9 -5.1 Quinolinate synthetase A (NCBI) compare
Rru_A2440 -0.9 -2.2 NADH:ubiquinone oxidoreductase 17.2 kD subunit (NCBI) compare
Rru_A3424 -0.9 -1.2 Orotidine-5'-phosphate decarboxylase (NCBI) compare
Rru_A2163 -0.9 -0.9 conserved hypothetical protein RP631 (NCBI) compare
Rru_A0637 -0.9 -1.2 hypothetical protein (NCBI) compare
Rru_A2164 -0.9 -2.8 Protein of unknown function UPF0118 (NCBI) compare
Rru_A3359 -0.9 -3.7 Cobyrinic acid a,c-diamide synthase CbiA (NCBI) compare
Rru_A1617 -0.9 -1.7 Protein of unknown function DUF1289 (NCBI) compare
Rru_A0922 -0.9 -0.8 Protein of unknown function DUF1044 (NCBI) compare
Rru_A2111 -0.9 -2.7 hypothetical protein (NCBI) compare
Rru_A3277 -0.9 -1.6 Acetylornithine and succinylornithine aminotransferase (NCBI) compare
Rru_A1433 -0.9 -2.3 L-aspartate oxidase (NCBI) compare
Rru_A1648 -0.8 -0.7 Helix-turn-helix protein, CopG (NCBI) compare
Rru_A2650 -0.8 -3.1 hypothetical protein (NCBI) compare
Rru_A1326 -0.8 -3.8 hypothetical protein (NCBI) compare
Rru_A1061 -0.8 -1.0 Helix-turn-helix protein, CopG (NCBI) compare
Rru_A2377 -0.8 -1.1 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain (NCBI) compare
Rru_A3627 -0.8 -2.1 Cobyrinic acid a,c-diamide synthase (NCBI) compare
Rru_A0296 -0.8 -0.8 hypothetical protein (NCBI) compare
Rru_A0753 -0.8 -4.6 Chaperone clpB (NCBI) compare
Rru_A3762 -0.8 -1.5 Peptidase M15D, vanX D-ala-D-ala dipeptidase (NCBI) compare
Rru_A0151 -0.8 -1.0 hypothetical protein (NCBI) compare
Rru_A0683 -0.8 -0.4 3-deoxy-7-phosphoheptulonate synthase (NCBI) compare
Rru_A3696 -0.8 -1.4 Exodeoxyribonuclease III xth (NCBI) compare
Rru_A3238 -0.8 -2.2 hypothetical protein (NCBI) compare
Rru_A0164 -0.8 -4.2 Sulfate transporter/antisigma-factor antagonist (NCBI) compare
Rru_A0207 -0.8 -1.6 Cobalt chelatase, CobT subunit (NCBI) compare
Rru_A1900 -0.8 -0.9 Transcriptional Regulator, AsnC family (NCBI) compare
Rru_A0100 -0.8 -0.5 hypothetical protein (NCBI) compare
Rru_A0721 -0.8 -2.0 Anti-Sigm factor, ChrR (NCBI) compare
Rru_A3328 -0.8 -2.4 OmpA/MotB (NCBI) compare
Rru_A3549 -0.8 -3.1 Cobyric acid synthase CobQ (NCBI) compare
Rru_A2195 -0.8 -2.1 Bacterioferritin (NCBI) compare
Rru_A3338 -0.8 -0.8 Protein of unknown function DUF37 (NCBI) compare
Rru_A2057 -0.8 -0.7 Molybdopterin-guanine dinucleotide biosynthesis MobB region (NCBI) compare
Rru_A0260 -0.8 -2.9 Protein of unknown function DUF466 (NCBI) compare
Rru_A3540 -0.8 -1.5 hypothetical protein (NCBI) compare
Rru_A2951 -0.8 -0.7 hypothetical protein (NCBI) compare
Rru_A0490 -0.8 -1.0 transport system permease protein (NCBI) compare
Rru_A0527 -0.8 -1.1 hypothetical protein (NCBI) compare
Rru_A1771 -0.7 -0.9 Sec-independent periplasmic protein translocase (NCBI) compare
Rru_A1884 -0.7 -1.1 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) compare
Rru_A3399 -0.7 -1.5 Transcriptional Regulator, BadM/Rrf2 family (NCBI) compare
Rru_A3742 -0.7 -1.2 CBS (NCBI) compare
Rru_A1999 -0.7 -0.9 hypothetical protein (NCBI) compare
Rru_A2017 -0.7 -2.0 hypothetical protein (NCBI) compare
Rru_A3318 -0.7 -2.4 Gamma-glutamyltransferase (NCBI) compare
Rru_A3382 -0.7 -2.3 Cobalamin biosynthesis protein CbiB (NCBI) compare
Rru_A0206 -0.7 -0.9 Cobalt chelatase, pCobS small subunit (NCBI) compare
Rru_A2500 -0.7 -1.3 Rhodanese-like (NCBI) compare
Rru_A0615 -0.7 -0.8 photosynthetic complex assembly protein (NCBI) compare
Rru_A3527 -0.7 -1.6 Protein of unknown function YGGT (NCBI) compare
Rru_A0854 -0.7 -2.6 Sulfotransferase (NCBI) compare
Rru_A0909 -0.7 -1.4 Propanediol utilization protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Rhodospirillum rubrum S1H in carbon source experiments

For carbon source Succinic Acid across organisms