Experiment set3IT011 for Caulobacter crescentus NA1000

Compare to:

PYE with Nalidixic acid sodium salt 0.06 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
CCNA_02171 +5.9 32.2 nucleoside permease nupC compare
CCNA_03832 +5.8 18.2 TetR-family transcriptional regulator compare
CCNA_02941 +5.7 9.6 transcription elongation factor greA compare
CCNA_02037 +5.2 30.8 ATP-dependent endopeptidase Lon compare
CCNA_01964 +5.2 27.9 NADH dehydrogenase compare
CCNA_01826 +4.9 21.7 vitamin B12 receptor compare
CCNA_03849 +4.8 18.0 fructokinase compare
CCNA_01061 +4.7 13.0 type I secretion adaptor protein RsaE compare
CCNA_01060 +4.6 15.1 type I protein secretion ATP-binding protein RsaD compare
CCNA_00392 +4.5 26.4 dihydroorotase compare
CCNA_02328 +4.5 2.5 cell cycle regulatory protein GcrA compare
CCNA_01251 +4.2 14.7 FepC-type transporter protein compare
CCNA_01250 +4.1 20.8 FecCD-family transporter protein compare
CCNA_01677 +3.9 15.4 carboxypeptidase G2 precursor compare
CCNA_03453 +3.9 11.5 AcrR-family transcriptional regulator compare
CCNA_02250 +3.8 12.0 methylcrotonyl-CoA carboxylase biotin-containing subunit compare
CCNA_02297 +3.8 13.9 hypoxanthine-guanine phosphoribosyltransferase compare
CCNA_00562 +3.8 22.0 dihydroorotate dehydrogenase compare
CCNA_00766 +3.7 20.4 cobalamin adenosyltransferase family protein compare
CCNA_01249 +3.7 15.0 ABC-transporter substrate binding protein compare
CCNA_02387 +3.6 24.4 glutathione reductase compare
CCNA_02026 +3.6 10.1 hypothetical protein compare
CCNA_00255 +3.6 5.5 esterase compare
CCNA_02252 +3.5 12.0 methylcrotonyl-CoA carboxylase carboxyl transferase subunit compare
CCNA_03281 +3.5 24.6 AsnC-family transcriptional regulator compare
CCNA_00769 +3.4 14.5 TetR family transcriptional regulator compare
CCNA_03353 +3.4 20.3 metallophosphatase domain protein compare
CCNA_02242 +3.4 25.0 PHB granule-associated protein, phasin2 compare
CCNA_02028 +3.3 2.6 NTF2 superfamily protein compare
CCNA_00962 +3.3 13.9 MarR-family transcriptional regulator compare
CCNA_02000 +3.3 6.3 SSU ribosomal protein S2P compare
CCNA_03612 +3.2 19.7 HTH XRE-family transcriptional regulator compare
CCNA_02030 +3.2 16.1 hypothetical protein compare
CCNA_01525 +3.2 12.3 flagellar biosynthesis repressor flbT compare
CCNA_03393 +3.1 9.7 phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit compare
CCNA_00852 +2.9 4.7 TetR family transcriptional regulator compare
CCNA_02459 +2.9 21.1 methylmalonyl-CoA mutase alpha subunit compare
CCNA_02583 +2.9 9.0 phosphoribosylformylglycinamidine synthase I compare
CCNA_02419 +2.9 8.1 TonB1 protein compare
CCNA_02324 +2.9 14.6 heat shock protein 33 hsp33 compare
CCNA_01063 +2.9 12.0 UDP-perosamine 4-acetyl transferase compare
CCNA_03043 +2.8 9.2 type IV pilin protein pilA compare
CCNA_02732 +2.8 9.4 hypothetical protein compare
CCNA_03805 +2.7 13.4 PadR-family transcriptional regulator compare
CCNA_03064 +2.7 11.3 PadR-family transcriptional regulator compare
CCNA_00028 +2.7 7.0 TonB-dependent receptor compare
CCNA_01712 +2.7 15.0 CopY/TcrY family transcriptional repressor compare
CCNA_02957 +2.7 10.5 ArsR-family transcriptional regulator compare
CCNA_00001 +2.7 4.7 ATP/GTP-binding protein compare
CCNA_02458 +2.6 17.8 methylmalonyl-CoA mutase beta subunit compare
CCNA_00011 +2.6 5.2 chaperone protein DnaJ compare
CCNA_03646 +2.6 18.9 ATPase compare
CCNA_00389 +2.6 2.9 aminomethyltransferase family protein compare
CCNA_03824 +2.5 14.9 2-polyprenylphenol 6-hydroxylase accessory protein UbiB compare
CCNA_01414 +2.5 11.8 3-hydroxyisobutyryl-CoA hydrolase compare
CCNA_00505 +2.5 11.4 ubiquinol-cytochrome c reductase iron-sulfur subunit compare
CCNA_03689 +2.5 16.0 alanine dehydrogenase compare
CCNA_03252 +2.5 15.6 CopY/TcrY-family transcriptional regulator compare
CCNA_00161 +2.5 10.6 hypothetical protein compare
CCNA_02577 +2.5 5.4 phosphoribosylformylglycinamidine synthase, purS component compare
CCNA_03287 +2.4 16.7 PadR-family transcriptional regulator compare
CCNA_02103 +2.4 14.8 hypothetical protein compare
CCNA_02691 +2.4 13.3 TetR-family transcriptional regulator compare
CCNA_02448 +2.4 13.8 hypothetical protein compare
CCNA_02180 +2.4 3.9 iron-sulfur cluster assembly/repair protein ApbC compare
CCNA_02225 +2.4 11.5 ArsR family/SAM-dependent transcriptional regulator compare
CCNA_00699 +2.4 7.9 LSU ribosomal protein L28P compare
CCNA_01815 +2.4 14.5 nitrogen assimilation regulatory protein NtrC compare
CCNA_01851 +2.4 14.4 quinol cytochrome oxidase polypeptide II compare
CCNA_02980 +2.4 13.2 tryptophan 2,3-dioxygenase compare
CCNA_00968 +2.3 15.6 gluconate kinase compare
CCNA_03150 +2.3 2.9 hypothetical protein compare
CCNA_02575 +2.3 4.8 hypothetical protein compare
CCNA_00518 +2.3 10.2 LSU ribosomal protein L25P compare
CCNA_00521 +2.3 1.9 antitoxin protein compare
CCNA_02646 +2.3 3.5 cell division protein MraZ compare
CCNA_03271 +2.3 15.3 methionine gamma-lyase compare
CCNA_03464 +2.3 6.8 glycine cleavage system H protein compare
CCNA_02011 +2.3 9.3 methylmalonyl CoA epimerase compare
CCNA_01242 +2.2 14.5 amino acid permease compare
CCNA_00362 +2.2 6.7 zinc uptake regulation protein compare
CCNA_03289 +2.2 7.1 HicB-family RNA-binding protein compare
CCNA_03519 +2.2 5.0 PadR-family transcriptional regulator compare
CCNA_02025 +2.2 7.6 hypothetical protein compare
CCNA_01059 +2.2 11.9 S-layer protein rsaA compare
CCNA_01453 +2.2 5.9 electron transport complex I subunit, NADH-ubiquinone oxidoreductase compare
CCNA_00924 +2.2 9.0 MarR/EmrR family transcriptional regulator compare
CCNA_00032 +2.2 5.8 antitoxin protein VapB compare
CCNA_02658 +2.1 5.2 3-hydroxybutyryl-CoA dehydratase compare
CCNA_01444 +2.1 8.4 poly(3-hydroxyalkanoate) polymerase compare
CCNA_02567 +2.1 11.1 sensory transduction histidine kinase pleC compare
CCNA_01168 +2.1 3.6 3-ketoacyl-CoA thiolase compare
CCNA_03858 +2.1 12.4 protein translocase subunit secB compare
CCNA_01763 +2.1 10.4 multifunctional aminopeptidase compare
CCNA_01684 +2.1 7.9 phenylalanine-4-hydroxylase compare
CCNA_01954 +2.0 3.7 ribonuclease E compare
CCNA_03030 +2.0 9.1 cytochrome c2 compare
CCNA_01979 +2.0 6.5 LexA repressor compare
CCNA_03513 +2.0 7.5 cytochrome c oxidase subunit III coxC compare
CCNA_01186 +2.0 5.2 hypothetical protein compare
CCNA_03392 +2.0 6.0 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit compare
CCNA_02663 +2.0 4.0 DnaK suppressor protein DksA compare
CCNA_03959 +2.0 1.8 hypothetical protein compare
CCNA_00153 +2.0 4.2 adenine nucleotide exchange factor GrpE compare
CCNA_01622 +2.0 5.9 Rsh ppGpp hydrolase-synthetase compare
CCNA_02553 +2.0 13.6 ATP-dependent clp protease ATP-binding subunit ClpA compare
CCNA_03479 +1.9 10.0 MarR-family transcriptional regulator compare
CCNA_00043 +1.9 7.8 N utilization substance protein A NusA compare
CCNA_01850 +1.9 11.7 quinol cytochrome oxidase polypeptide I compare
CCNA_01420 +1.9 7.8 NrdR family transcriptional regulator compare
CCNA_03062 +1.9 10.2 cell wall hydrolase family protein compare
CCNA_01624 +1.9 3.5 orotate phosphoribosyltransferase compare
CCNA_02698 +1.9 10.9 Inosine-uridine nucleoside N-ribohydrolase compare
CCNA_01295 +1.9 9.3 integral membrane protein compare
CCNA_03863 +1.9 6.6 hypothetical protein compare
CCNA_02021 +1.9 8.8 hypothetical protein compare
CCNA_02447 +1.9 11.2 PspA/IM30 family regulatory protein compare
CCNA_00846 +1.9 14.6 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase compare
CCNA_00471 +1.9 10.1 GDP-L-fucose synthase compare
CCNA_02619 +1.9 10.6 stomatin/prohibitin-related protein compare
CCNA_01141 +1.8 8.2 RecA protein compare
CCNA_01361 +1.8 3.7 PepSY superfamily protein compare
CCNA_01942 +1.8 7.4 Rrf2 family protein compare
CCNA_00162 +1.8 6.6 hypothetical protein compare
CCNA_01176 +1.8 2.0 hypothetical protein compare
CCNA_00939 +1.8 7.0 MarR-family transcriptional regulator compare
CCNA_00104 +1.7 6.9 orotidine 5'-phosphate decarboxylase compare
CCNA_01814 +1.7 10.1 nitrogen regulation protein ntrB compare
CCNA_02376 +1.7 1.7 hypothetical protein compare
CCNA_00027 +1.7 2.3 2OG-Fe(II) oxygenase compare
CCNA_03136 +1.7 4.8 flagellar export protein FliJ compare
CCNA_03989 +1.7 10.5 MarR-family HTH transcriptional regulator / N-acyltransferase compare
CCNA_02552 +1.7 3.3 ATP-dependent Clp protease adaptor protein ClpS compare
CCNA_02586 +1.7 7.6 phosphoribosylformylglycinamidine synthase II compare
CCNA_03762 +1.7 3.7 acetolactate synthase-related protein compare
CCNA_02616 +1.7 10.8 4-hydroxyphenylpyruvate dioxygenase compare
CCNA_01593 +1.7 6.4 Xaa-pro aminopeptidase compare
CCNA_01848 +1.6 6.7 quinol cytochrome oxidase polypeptide IV compare
CCNA_01849 +1.6 7.9 quinol cytochrome oxidase polypeptide III compare
CCNA_02414 +1.6 5.1 DadA-related amino acid oxidase compare
CCNA_00506 +1.6 7.7 cytochrome b compare
CCNA_00036 +1.6 1.8 ribosome-binding factor A compare
CCNA_01279 +1.6 4.9 inorganic polyphosphate/ATP-NAD kinase compare
CCNA_00299 +1.6 6.3 phosphoribosylamine--glycine ligase compare
CCNA_R0037 +1.6 2.9 tRNA-Glu compare
CCNA_03557 +1.6 7.2 hypothetical protein compare
CCNA_00163 +1.6 9.8 exopolysaccharide transport family protein compare
CCNA_01823 +1.6 2.3 hypothetical protein compare
CCNA_00768 +1.6 3.5 hypothetical protein compare
CCNA_03108 +1.6 12.0 TonB-dependent outer membrane receptor compare
CCNA_03123 +1.6 6.2 ArsR-family transcriptional regulator compare
CCNA_01270 +1.6 2.4 hypothetical protein compare
CCNA_01690 +1.5 3.0 MAPEG family membrane protein compare
CCNA_02617 +1.5 10.7 histidinol-phosphate aminotransferase compare
CCNA_00999 +1.5 4.1 PAS-family motility and cell cycle regulatory protein MopJ compare
CCNA_03936 +1.5 4.1 hypothetical protein compare
CCNA_03325 +1.5 5.6 hypothetical protein compare
CCNA_00705 +1.5 2.3 hypothetical protein compare
CCNA_01655 +1.5 5.7 cyclophilin-type peptidylprolyl cis-trans isomerase compare
CCNA_01691 +1.5 5.0 tRNA/rRNA methyltransferase compare
CCNA_02066 +1.5 5.3 phytoene/squalene synthase family protein compare
CCNA_00013 +1.5 10.3 protein-PII uridylyltransferase compare
CCNA_00397 +1.5 10.0 acetolactate synthase compare
CCNA_00006 +1.5 5.7 enoyl-CoA hydratase compare
CCNA_03553 +1.5 5.6 diadenosine tetraphosphate (Ap4A) hydrolase compare
CCNA_00752 +1.5 8.4 3-hydroxybutyryl-CoA dehydrogenase compare
CCNA_03992 +1.5 1.0 UDP-glucose 6-dehydrogenase-related protein compare
CCNA_01931 +1.5 7.2 TetR-family transcriptional regulator compare
CCNA_03617 +1.5 5.0 Copper(I)-binding protein compare
CCNA_03514 +1.5 8.2 cytochrome c oxidase assembly protein ctaG compare
CCNA_00998 +1.5 5.5 ROS/MUCR transcriptional regulator compare
CCNA_02330 +1.4 5.1 hypothetical protein compare
CCNA_01926 +1.4 4.8 GGDEF diguanylate cyclase DgcB compare
CCNA_03420 +1.4 5.3 hypothetical protein compare
CCNA_02384 +1.4 6.6 very-long-chain acyl-CoA synthetase compare
CCNA_01276 +1.4 2.7 cytochrome c5 compare
CCNA_00675 +1.4 5.9 VapC-like PIN domain ribonuclease compare
CCNA_03963 +1.4 2.5 hypothetical protein compare
CCNA_01058 +1.4 5.7 helix-turn-helix transcriptional regulator compare
CCNA_01846 +1.4 6.7 two-component sensor histidine kinase compare
CCNA_01066 +1.4 7.9 glycosyltransferase compare
CCNA_01840 +1.4 8.9 MerR-family transcriptional regulator compare
CCNA_00215 +1.4 7.4 SapC surface layer protein compare
CCNA_01717 +1.4 3.4 hypothetical protein compare
CCNA_00059 +1.3 4.4 oxygen-insensitive NADH nitroreductase compare
CCNA_02644 +1.3 2.8 cell division protein FtsL compare
CCNA_03089 +1.3 6.0 hypothetical protein compare
CCNA_03722 +1.3 11.0 glutamate synthase (NADPH) large chain GltB compare
CCNA_00054 +1.3 5.8 tRNA 2-methylthioadenosine synthase compare
CCNA_03524 +1.3 4.2 di-/tripeptide transporter compare
CCNA_02109 +1.3 3.5 thiamine biosynthesis protein thiC compare
CCNA_01670 +1.3 4.9 sulfate transport ATP-binding protein cysA compare
CCNA_01742 +1.3 5.7 hypothetical protein compare
CCNA_01412 +1.3 6.0 acyl-CoA dehydrogenase, short-chain specific compare
CCNA_02591 +1.3 5.1 glutaredoxin compare
CCNA_01845 +1.3 5.8 two-component response regulator protein compare
CCNA_03961 +1.3 3.5 hypothetical protein compare
CCNA_02339 +1.3 7.9 methyltransferase compare
CCNA_01415 +1.3 6.8 methyltransferase compare
CCNA_01573 +1.3 6.3 ArsR-family transcriptional regulator compare


Specific Phenotypes

For 8 genes in this experiment

For stress Nalidixic acid sodium salt in Caulobacter crescentus NA1000

For stress Nalidixic acid sodium salt across organisms