Experiment set3IT002 for Sinorhizobium meliloti 1021

Compare to:

L-Histidine nitrogen source

200 most important genes:

  gene name fitness t score description  
SMc04045 -6.7 -4.6 dihydroxy-acid dehydratase compare
SMc01801 -6.7 -2.6 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc02245 -6.5 -4.5 dihydroorotate dehydrogenase 2 compare
SMc01726 -6.2 -5.3 acetylglutamate kinase compare
SMa1635 -6.2 -1.4 hypothetical protein compare
SMc01361 -6.0 -3.9 dihydroorotase compare
SMc02717 -5.8 -15.9 2-isopropylmalate synthase compare
SMc00711 -5.8 -4.0 cyclohexadienyl dehydrogenase compare
SMc00640 -5.7 -10.2 phosphoserine aminotransferase compare
SMc03229 -5.7 -2.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03823 -5.6 -10.9 isopropylmalate isomerase large subunit compare
SMc00815 -5.3 -2.0 inosine 5'-monophosphate dehydrogenase compare
SMc03979 -5.3 -2.3 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00493 -5.2 -5.3 phosphoribosylformylglycinamidine synthase I compare
SMc03112 -5.0 -18.6 B12-dependent methionine synthase compare
SMc01494 -4.9 -10.4 phosphoserine phosphatase compare
SMc00615 -4.8 -9.7 phosphoribosylaminoimidazole synthetase compare
SMc00488 -4.8 -14.5 phosphoribosylformylglycinamidine synthase II compare
SMc04405 -4.7 -8.8 3-isopropylmalate dehydrogenase compare
SMc03899 -4.6 -1.0 hypothetical protein compare
SMc04028 -4.6 -19.5 glutamate synthase compare
SM_b21480 -4.6 -1.0 hypothetical protein compare
SMc02899 -4.6 -8.3 prephenate dehydratase compare
SMc00053 -4.5 -1.0 monovalent cation/H+ antiporter subunit C compare
SMc02725 -4.4 -8.6 anthranilate synthase compare
SMc02765 -4.4 -14.0 tryptophan synthase subunit alpha compare
SMc00494 -4.4 -1.4 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc02166 -4.4 -10.7 dihydroorotase compare
SMc01431 -4.4 -12.1 acetolactate synthase 3 catalytic subunit compare
SMc02217 -4.4 -5.8 O-succinylhomoserine sulfhydrylase compare
SMc04002 -4.4 -4.8 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc03826 -4.4 -3.1 argininosuccinate synthase compare
SMc03978 -4.3 -3.0 transketolase compare
SMc00554 -4.3 -9.0 amidophosphoribosyltransferase compare
SMa1002 -4.3 -1.9 hypothetical protein compare
SMc01569 -4.3 -1.3 carbamoyl phosphate synthase small subunit compare
SMa0955 -4.3 -1.6 GntR family transcriptional regulator compare
SMc00726 -4.3 -0.9 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc02137 -4.3 -3.5 ornithine carbamoyltransferase compare
SMc01360 -4.2 -3.8 aspartate carbamoyltransferase catalytic subunit compare
SMc01843 -4.2 -8.5 5,10-methylenetetrahydrofolate reductase compare
SMc03070 -4.2 -7.5 glucose-6-phosphate 1-dehydrogenase compare
SMc02165 -4.2 -9.8 orotate phosphoribosyltransferase compare
SMc03777 -4.1 -6.7 gamma-glutamyl phosphate reductase compare
SMc02767 -4.0 -5.1 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc01880 -4.0 -2.6 pantoate--beta-alanine ligase compare
SMc01215 -3.9 -2.7 carbamoyl phosphate synthase large subunit compare
SMc02246 -3.8 -0.8 hypothetical protein compare
SMc00236 -3.7 -3.7 Indole-3-glycerol phosphate synthase compare
SMc00235 -3.7 -5.9 anthranilate phosphoribosyltransferase compare
SMc02766 -3.7 -10.0 tryptophan synthase subunit beta compare
SMc02755 -3.7 -6.6 S-adenosyl-L-homocysteine hydrolase compare
SMc03776 -3.5 -2.6 gamma-glutamyl kinase compare
SMc04026 -3.5 -7.5 glutamate synthase compare
SMc03797 -3.5 -5.6 homoserine O-succinyltransferase compare
SMc00641 -3.4 -5.3 D-3-phosphoglycerate dehydrogenase compare
SMc00492 -3.4 -0.7 hypothetical protein compare
SMc00614 -3.3 -6.6 phosphoribosylglycinamide formyltransferase compare
SM_b21175 -3.3 -3.4 phosphate uptake ABC transporter permease compare
SMc00017 -3.3 -1.0 homoserine kinase compare
SMc00993 -3.3 -6.6 phosphoribosylamine--glycine ligase compare
SMc00495 -3.3 -4.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc04088 -3.3 -8.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc01881 -3.2 -3.2 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00293 -3.2 -6.7 homoserine dehydrogenase compare
SMc00010 -3.1 -1.9 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc02707 -3.1 -2.7 hypothetical protein compare
SMc00353 -3.1 -2.1 transmembrane protein compare
SMc02138 -3.0 -6.2 acetylornithine transaminase compare
SMc04391 -3.0 -1.8 3-ketoacyl-ACP reductase compare
SMc00963 -2.9 -3.0 hypothetical protein compare
SMc04330 -2.9 -2.3 trimethylamine methyltransferase compare
SMc00673 -2.9 -9.6 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) conserved
SMc02363 -2.9 -3.9 cytochrome C-type biogenesis transmembrane protein compare
SMc00412 -2.8 -4.2 orotidine 5'-phosphate decarboxylase compare
SMc03795 -2.8 -1.2 isopropylmalate isomerase small subunit compare
SMc00013 -2.8 -2.4 cytochrome C oxidase subunit III transmembrane protein compare
SMc00302 -2.8 -2.2 hypothetical protein compare
SMc01770 -2.7 -1.3 serine hydroxymethyltransferase compare
SMc03068 -2.7 -8.1 phosphogluconate dehydratase compare
SMc01153 -2.7 -0.8 enoyl-CoA hydratase compare
SMc03763 -2.7 -2.7 cytosine-specific methyltransferase compare
SMc00450 -2.7 -2.5 protoheme IX farnesyltransferase compare
SMc02231 -2.6 -2.1 hypothetical protein compare
SMc02495 -2.6 -1.4 translaldolase compare
SM_b20048 -2.5 -5.6 transcriptional regulator compare
SMc00294 -2.5 -5.2 aminotransferase compare
SMc04346 -2.5 -4.3 ketol-acid reductoisomerase compare
SMa0789 -2.5 -3.6 GntR family transcriptional regulator compare
SMc02229 -2.4 -7.4 acyl-CoA dehydrogenase compare
SM_b21164 -2.3 -3.4 N-formylglutamate deformylase (EC 3.5.1.68) (from data) compare
SM_b21176 -2.3 -3.1 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc01568 -2.3 -1.6 hypothetical protein compare
SMa2289 -2.3 -1.1 hypothetical protein compare
SMc02140 -2.2 -1.9 phosphate regulon transcriptional regulatory protein compare
SMc01430 -2.2 -2.0 acetolactate synthase 3 regulatory subunit compare
SMc03924 -2.2 -6.1 glycogen synthase compare
SMc02697 -2.2 -1.3 hypothetical protein compare
SM_b20904 -2.2 -2.8 sugar uptake ABC transporter ATP-binding protein compare
SMa1625 -2.2 -2.5 LysR family transcriptional regulator compare
SM_b21174 -2.1 -3.7 phosphate uptake ABC transporter permease compare
SM_b21545 -2.1 -2.6 two-component response regulator protein compare
SMc01147 -2.1 -3.3 coproporphyrinogen III oxidase compare
SMc00131 -2.1 -7.1 transcriptional regulator compare
SMa2215 -2.0 -2.8 GntR family transcriptional regulator compare
SMc04121 -2.0 -1.6 uracil phosphoribosyltransferase compare
SMc02362 -2.0 -2.7 cytochrome c-type biogenesis protein CcmE compare
SMc01556 -2.0 -2.0 hypothetical protein compare
SM_b21163 -2.0 -6.0 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
SMc02115 -1.9 -1.0 hypothetical protein compare
SM_b21679 -1.9 -1.2 hypothetical protein compare
SMc01800 -1.9 -1.0 cytochrome C oxidase assembly transmembrane protein compare
SMc02685 -1.9 -3.0 hypothetical protein compare
SMc03053 -1.9 -1.3 flagellar biosynthesis protein FliQ compare
SMc00555 -1.9 -0.9 colicin V production transmembrane protein compare
SMc02173 -1.9 -1.4 hypothetical protein compare
SMc01578 -1.9 -6.2 aspartate aminotransferase compare
SM_b21177 -1.9 -4.2 phosphate uptake ABC transporter ATP-binding protein compare
SMc02147 -1.8 -4.7 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02636 -1.8 -2.1 hypothetical protein compare
SMc01242 -1.8 -2.0 signal peptide protein compare
SMc02227 -1.8 -3.9 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02983 -1.7 -4.0 ornithine, DAP, or arginine decarboxylase compare
SM_b21166 -1.7 -3.9 Imidazolonepropionase (EC 3.5.2.7) (from data) compare
SMc01577 -1.7 -1.2 hypothetical protein compare
SMc04001 -1.7 -0.6 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc03878 -1.7 -2.5 acetoacetyl-CoA reductase compare
SMc02232 -1.7 -2.7 hypothetical protein compare
SMc01440 -1.7 -2.9 hydrolase serine protease transmembrane protein compare
SMc04337 -1.6 -3.1 hypothetical protein compare
SMc01241 -1.6 -2.0 hypothetical protein compare
SMc01505 -1.6 -1.0 hypothetical protein compare
SMc02451 -1.6 -1.2 hypothetical protein compare
SMc02338 -1.6 -1.3 periplasmic binding ABC transporter protein compare
SM_b21165 -1.6 -4.0 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
SMc00619 -1.6 -1.4 hypothetical protein compare
SMc00821 -1.6 -1.1 hypothetical protein compare
SMc02897 -1.6 -1.9 cytochrome C transmembrane protein compare
SMc03184 -1.6 -0.9 PH adaptation potassium efflux system G transmembrane protein compare
SMc02753 -1.5 -1.1 PTS system transporter subunit IIA compare
SM_b20903 -1.5 -4.6 sugar uptake ABC transporter permease compare
SM_b20758 -1.5 -1.2 ArsR family transcriptional regulator compare
SMc03981 -1.5 -2.6 phosphoglycerate kinase compare
SMc03153 -1.5 -2.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase compare
SM_b20691 -1.5 -2.0 hypothetical protein compare
SMc02046 -1.5 -1.0 hypothetical protein compare
SMc02228 -1.5 -3.2 acetyl-CoA acetyltransferase compare
SMc02484 -1.5 -2.5 amino acid efflux transmembrane protein compare
SMc02055 -1.5 -1.2 phytoene synthase compare
SMc02434 -1.5 -2.0 hypothetical protein compare
SMc04453 -1.5 -0.8 hypothetical protein compare
SM_b20563 -1.4 -1.9 hypothetical protein compare
SMc01124 -1.4 -4.9 PII uridylyl-transferase compare
SMc01187 -1.4 -1.0 rare lipoprotein A compare
SMc01974 -1.4 -1.7 transcriptional regulator compare
SMc00854 -1.4 -1.2 hypothetical protein compare
SMc02693 -1.4 -0.9 peptidyl-tRNA hydrolase compare
SMc02071 -1.4 -2.1 hydrolase glycosidase compare
SMc01850 -1.4 -1.7 hypothetical protein compare
SMc00981 -1.4 -2.8 ferredoxin protein compare
SMa0760 -1.4 -1.8 FixT2 anti-kinase compare
SMc00467 -1.4 -3.0 hypothetical protein compare
SMc01214 -1.3 -2.0 zinc-containing alcohol dehydrogenase compare
SMc02833 -1.3 -1.3 penicillin-insensitive murein endopeptidase compare
SMc02856 -1.3 -6.6 penicillin-binding protein compare
SM_b20105 -1.3 -1.1 transcriptional regulator compare
SMc01097 -1.3 -2.5 hypothetical protein compare
SMc02470 -1.3 -2.6 transcriptional regulator compare
SM_b20701 -1.3 -0.7 hypothetical protein compare
SMc00982 -1.3 -2.8 dioxygenase compare
SMc00461 -1.3 -0.8 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
SMc00296 -1.3 -4.4 POLY3-hydroxybutyrate polymerase compare
SMc00712 -1.3 -1.2 hypothetical protein compare
SMc01441 -1.3 -1.7 membrane bound protease compare
SM_b21598 -1.3 -3.4 transcriptional regulator compare
SMc03100 -1.2 -0.6 hypothetical protein compare
SMc03801 -1.2 -1.1 thioredoxin protein compare
SMa1943 -1.2 -2.0 transcriptional regulator compare
SM_b20413 -1.2 -0.6 hypothetical protein compare
SMc01579 -1.2 -0.6 hypothetical protein compare
SMc00166 -1.2 -0.9 oxidoreductase NAD protein compare
SMc00959 -1.2 -1.3 hypothetical protein compare
SM_b20902 -1.2 -4.9 sugar uptake ABC transporter substrate-binding protein precursor compare
SM_b21524 -1.2 -1.4 septum formation inhibitor compare
SMc01007 -1.2 -1.0 hypothetical protein compare
SM_b20350 -1.2 -1.4 hypothetical protein compare
SMc03236 -1.2 -1.4 glutamine amidotransferase compare
SMc02058 -1.2 -1.1 YAJC protein compare
SMc03175 -1.2 -2.1 nucleoside hydrolase compare
SMc02051 -1.2 -1.1 hypothetical protein compare
SMc02449 -1.1 -1.7 acetyltransferase compare
SMc04246 -1.1 -1.0 transmembrane signal peptide protein compare
SMa0126 -1.1 -1.0 CspA8 Cold shock family protein compare
SM_b20031 -1.1 -2.0 hypothetical protein compare
SMa1243 -1.1 -2.2 Azu1 pseudoazurin compare
SMa1063 -1.1 -0.9 hypothetical protein compare
SM_b20226 -1.1 -1.2 hypothetical protein compare
SMc01757 -1.1 -1.4 hypothetical protein compare
SM_b20089 -1.1 -1.1 hypothetical protein compare
SMc00876 -1.1 -2.6 ATP-binding MRP protein compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen source L-Histidine in Sinorhizobium meliloti 1021

For nitrogen source L-Histidine across organisms