Experiment set3H5 for Shewanella oneidensis MR-1

Compare to:

L-Isoleucine carbon source replicate 1

200 most detrimental genes:

  gene name fitness t score description  
SO1665 galU +11.2 48.4 UTP-glucose-1-phosphate uridylyltransferase (NCBI ptt file) compare
SO4055 metL +9.8 75.5 aspartokinase II/homoserine dehydrogenase, methionine-sensitive (NCBI ptt file) compare
SO_t008 tRNA-Thr-1 +7.2 7.3 tRNA-Thr (RefSeq) compare
SO2537 +6.8 42.8 sodium/hydrogen exchanger family protein (NCBI ptt file) compare
SO2088 +6.5 7.1 lipid A biosynthesis acyltransferase, putative (NCBI ptt file) compare
SO3954 +6.5 17.3 ABC transporter, ATP-binding protein, putative (NCBI ptt file) compare
SO_2605 +6.3 15.5 no description compare
SO2336 pgm +6.2 8.5 phosphoglucomutase, alpha-D-glucose phosphate-specific (NCBI ptt file) compare
SO2606 +6.0 38.2 PqiB family protein (NCBI ptt file) compare
SO3745 rfaE +6.0 37.3 ADP-heptose synthase (NCBI ptt file) compare
SO3953 +5.9 19.2 conserved hypothetical protein TIGR00056 (NCBI ptt file) compare
SO3951 +5.6 17.1 conserved hypothetical protein (NCBI ptt file) compare
SO3952 +5.6 30.5 mce-related protein (NCBI ptt file) compare
SO3197 +5.6 25.4 vacJ lipoprotein, putative (NCBI ptt file) compare
SO1926 gltA +5.5 30.4 citrate synthase (NCBI ptt file) compare
SO2108 mdoH +5.4 18.6 periplasmic glucans biosynthesis protein MdoH (NCBI ptt file) compare
SO4678 +5.4 38.7 heptosyl transferase, glycosyltransferase family 9 protein (NCBI ptt file) compare
SO0217 tufB +5.3 5.7 translation elongation factor Tu (NCBI ptt file) compare
SO2604.1 +5.1 6.6 conserved hypothetical protein (NCBI ptt file) compare
SO0229 tufA +5.0 6.1 translation elongation factor Tu (NCBI ptt file) compare
SO2062 +4.8 6.9 conserved hypothetical protein (NCBI ptt file) compare
SO2739.1 +4.6 3.4 hypothetical protein (NCBI ptt file) compare
SO1818 +4.6 26.8 conserved hypothetical protein (NCBI ptt file) compare
SO2248 sdaA +4.6 17.8 L-serine dehydratase 1 (NCBI ptt file) compare
SO1344 rseB +4.4 11.8 sigma-E factor regulatory protein RseB (NCBI ptt file) compare
SO2268 hscA +4.4 5.5 chaperone protein HscA (NCBI ptt file) compare
SO0606 hflC +4.3 7.0 hflC protein (NCBI ptt file) compare
SO3194.1 +4.2 20.8 hypothetical peptide transporter (NCBI ptt file) compare
SO0163 hslO +4.2 22.3 chaperonin HslO (NCBI ptt file) compare
SO1095 +4.1 21.1 O-acetylhomoserine (thiol)-lyase, putative (NCBI ptt file) compare
SO3195 +3.8 7.2 hypothetical peptide transporter (NCBI ptt file) compare
SO0605 hflK +3.8 11.4 hflK protein (NCBI ptt file) compare
SO3227 fliG +3.6 12.6 flagellar motor switch protein FliG (NCBI ptt file) compare
SO2629 icd +3.5 19.3 isocitrate dehydrogenase, NADP-dependent (NCBI ptt file) compare
SO0702 +3.4 10.3 MATE efflux family protein (NCBI ptt file) compare
SO1819 dinG +3.3 17.5 ATP-dependent helicase DinG (NCBI ptt file) compare
SO3228 fliF +3.2 19.0 flagellar M-ring protein FliF (NCBI ptt file) compare
SO4680 +3.2 18.0 conserved hypothetical protein (NCBI ptt file) compare
SO1572 +3.1 5.6 hypothetical protein (NCBI ptt file) compare
SO2175 +2.8 12.7 conserved hypothetical protein (NCBI ptt file) compare
SO2887 dsbB +2.8 7.5 disulfide bond formation protein b (NCBI ptt file) compare
SO4118 +2.8 13.9 malate oxidoreductase, putative (NCBI ptt file) compare
SO2602 +2.8 3.9 hypothetical Activator of ProP osmoprotectant transporter (NCBI ptt file) compare
SO2869 +2.7 10.5 conserved hypothetical protein (NCBI ptt file) compare
SO3472 +2.7 9.6 ABC transporter, ATP-binding protein (NCBI ptt file) compare
SO2427 +2.6 10.8 TonB-dependent receptor, putative (NCBI ptt file) compare
SO1897 ivd +2.6 12.4 isovaleryl-CoA dehydrogenase (NCBI ptt file) compare
SO3210 fliA +2.5 6.4 RNA polymerase sigma-27 factor (NCBI ptt file) compare
SO1388 +2.4 11.9 aminopeptidase P, putative (NCBI ptt file) compare
SO3829 +2.4 4.3 conserved hypothetical protein (NCBI ptt file) compare
SOA0062 +2.4 8.0 hypothetical protein (NCBI ptt file) compare
SO1169 +2.4 4.8 conserved hypothetical protein TIGR00246 (NCBI ptt file) compare
SO2879 uraA +2.4 6.1 uracil permease (NCBI ptt file) compare
SO3895 +2.3 6.1 HesA/MoeB/ThiF family protein (NCBI ptt file) compare
SO4312 +2.2 13.1 adenylate cyclase CyaA, putative (NCBI ptt file) compare
SO0347 +2.2 7.3 acyltransferase family protein (NCBI ptt file) compare
SO3219 fliO +2.2 3.6 flagellar protein FliO (NCBI ptt file) compare
SO_t037 tRNA-Pro-4 +2.2 4.0 tRNA-Pro (RefSeq) compare
SO2476 +2.2 4.3 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO1529 pomA +2.1 3.8 chemotaxis motA protein (NCBI ptt file) compare
SOA0011 +2.1 5.8 conserved hypothetical protein (NCBI ptt file) compare
SO3215 flhB +2.1 8.7 flagellar biosynthetic protein FlhB (NCBI ptt file) compare
SO3558 +2.1 4.6 hypothetical protein (NCBI ptt file) compare
SO2487 edd +2.1 5.1 6-phosphogluconate dehydratase (NCBI ptt file) compare
SO3965 ptsO +2.1 3.9 phosphocarrier protein NPR (NCBI ptt file) compare
SO3250 flgB +2.1 5.5 flagellar basal-body rod protein FlgB (NCBI ptt file) compare
SO0410 mutT +2.0 2.5 mutator mutT protein (NCBI ptt file) compare
SO2923 gltS +2.0 6.0 sodium/glutamate symporter (NCBI ptt file) compare
SO0050 +2.0 2.9 rhodanese domain protein (NCBI ptt file) compare
SO0197 +2.0 9.0 fatty acid desaturase, family 1 (NCBI ptt file) compare
SO2437 +2.0 6.5 hypothetical protein (NCBI ptt file) compare
SO3109 +2.0 4.4 conserved hypothetical protein (NCBI ptt file) compare
SO3801 +1.9 8.4 ABC transporter, permease protein (NCBI ptt file) compare
SO3245 flgF +1.9 7.4 flagellar basal-body rod protein FlgF (NCBI ptt file) compare
SO3169 +1.9 2.0 transcriptional regulator, Cro/CI family (NCBI ptt file) compare
SO3497 +1.9 6.9 aminotransferase, class III (NCBI ptt file) compare
SO0290 +1.9 1.8 hypothetical protein (NCBI ptt file) compare
SO3217 fliQ +1.9 5.1 flagellar biosynthetic protein FliQ (NCBI ptt file) compare
SO2872 +1.9 1.5 conserved hypothetical protein (NCBI ptt file) compare
SO1267 +1.8 6.0 Gamma-glutamyl-gamma-aminobutyrate hydrolase (EC 3.5.1.94) (from data) compare
SO2350 aspC-1 +1.8 5.7 aspartate aminotransferase (NCBI ptt file) compare
SO0298 gmhA +1.8 6.1 phosphoheptose isomerase (NCBI ptt file) compare
SO4718 +1.8 10.5 sigma-54 dependent response regulator (NCBI ptt file) compare
SO2239 +1.8 2.5 conserved hypothetical protein (NCBI ptt file) compare
SO0417 +1.8 3.7 pilin, putative (NCBI ptt file) compare
SO4257 +1.8 7.8 conserved hypothetical protein TIGR00255 (NCBI ptt file) compare
SO2832 +1.8 8.9 conserved hypothetical protein (NCBI ptt file) compare
SO2014 +1.8 2.3 conserved hypothetical protein TIGR00103 (NCBI ptt file) compare
SO1935 rnk +1.8 2.6 regulator of nucleoside diphosphate kinase (NCBI ptt file) compare
SO1052 pit +1.8 8.4 low-affinity inorganic phosphate transporter (NCBI ptt file) compare
SO1793 tig +1.8 3.2 trigger factor (NCBI ptt file) compare
SO4727 +1.7 4.7 conserved hypothetical protein (NCBI ptt file) compare
SO1901 sugE +1.7 1.4 sugE protein (NCBI ptt file) compare
SO3206 cheB-3 +1.7 7.2 protein-glutamate methylesterase CheB (NCBI ptt file) compare
SO1784 feoB +1.7 3.3 ferrous iron transport protein B (NCBI ptt file) compare
SO2504 +1.7 3.7 conserved hypothetical protein (NCBI ptt file) compare
SO2111 +1.7 2.1 hypothetical protein (NCBI ptt file) compare
SO3936 motX +1.7 6.4 sodium-type flagellar protein MotX (NCBI ptt file) compare
SO1268 +1.7 4.6 Glutamate--putrescine ligase (EC 6.3.1.11) (from data) compare
SO4699 prlC +1.7 10.6 oligopeptidase A (NCBI ptt file) compare
SO2417 +1.7 2.9 iron-sulfur cluster-binding protein (NCBI ptt file) compare
SO4679 +1.7 4.1 glycosyl transferase, group 1 family protein (NCBI ptt file) compare
SO1801 sapF +1.6 5.7 peptide ABC transporter, ATP-binding protein (NCBI ptt file) compare
SO4303 +1.6 5.2 hypothetical protein (NCBI ptt file) compare
SO0414 pilD +1.6 3.0 type 4 prepilin-like proteins leader peptide processing enzyme (NCBI ptt file) compare
SO0691 +1.6 4.0 hypothetical protein (NCBI ptt file) compare
SO3575 +1.6 5.8 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative (NCBI ptt file) compare
SO2852 +1.6 3.7 transcriptional regulator, GntR family (NCBI ptt file) compare
SO3112 yajC +1.6 1.3 preprotein translocase, YajC subunit (NCBI ptt file) compare
SO4508 +1.6 5.2 hypothetical protein (NCBI ptt file) compare
SO3216 fliR +1.6 4.8 flagellar biosynthetic protein FliR (NCBI ptt file) compare
SO3221 fliM +1.6 3.7 flagellar motor switch protein FliM (NCBI ptt file) compare
SO1790 ppiB-1 +1.6 1.7 peptidyl-prolyl cis-trans isomerase B (NCBI ptt file) compare
SO0624 crp +1.5 3.7 catabolite gene activator (NCBI ptt file) compare
SO3851 +1.5 1.3 hypothetical protein (NCBI ptt file) compare
SO2731 mdoG-2 +1.5 7.6 periplasmic glucans biosynthesis protein MdoG (NCBI ptt file) compare
SO3802 +1.5 4.5 ABC transporter, ATP-binding protein (NCBI ptt file) compare
SO0600 amiB +1.5 2.2 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
SO3828 +1.5 4.7 conserved hypothetical protein (NCBI ptt file) compare
SO_A0174 +1.5 2.2 hypothetical protein (NCBI) compare
SO2804 +1.5 5.8 conserved hypothetical protein (NCBI ptt file) compare
SO3790 +1.5 4.0 conserved hypothetical protein (NCBI ptt file) compare
SO0358 +1.5 4.8 endoribonuclease L-PSP, putative (NCBI ptt file) compare
SO3249 flgC +1.5 4.1 flagellar basal-body rod protein FlgC (NCBI ptt file) compare
SO1880 nlpB +1.5 6.7 lipoprotein-34 NlpB (NCBI ptt file) compare
SO3789 +1.4 7.5 aminotransferase, class V (NCBI ptt file) compare
SO1560 +1.4 4.6 phosphate-binding protein (NCBI ptt file) compare
SO3324 +1.4 3.7 acetyltransferase, GNAT family (NCBI ptt file) compare
SO3419 trpR +1.4 4.2 trp operon repressor (NCBI ptt file) compare
SO3244 flgG +1.4 8.6 flagellar basal-body rod protein FlgG (NCBI ptt file) compare
SO3147 +1.4 2.4 hypothetical protein (NCBI ptt file) compare
SO0548 +1.4 2.7 DNA-binding protein, HU family (NCBI ptt file) compare
SO3815 +1.4 4.8 conserved hypothetical protein (NCBI ptt file) compare
SO1274 +1.4 3.5 conserved hypothetical protein (NCBI ptt file) compare
SO0697 cutA +1.4 1.9 periplasmic divalent cation tolerance protein CutA (NCBI ptt file) compare
SOA0056 +1.4 1.6 hypothetical protein (NCBI ptt file) compare
SO3853 +1.4 1.3 hypothetical protein (NCBI ptt file) compare
SO1796 lon +1.4 5.8 ATP-dependent protease La (NCBI ptt file) compare
SO4702 gor +1.3 7.7 glutathione reductase (NCBI ptt file) compare
SO1663 napF +1.3 1.9 ferredoxin-type protein NapF (NCBI ptt file) compare
SO2477 +1.3 2.7 alcohol dehydrogenase, iron-containing (NCBI ptt file) compare
SO2640 +1.3 2.8 transcriptional regulator, MarR family (NCBI ptt file) compare
SO3270 +1.3 4.0 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO4651 +1.3 4.7 conserved hypothetical protein (NCBI ptt file) compare
SO3033 +1.3 3.8 ferric alcaligin siderophore receptor (NCBI ptt file) compare
SO_2754 +1.3 2.3 no description compare
SO3203 +1.3 1.8 CheW domain protein (NCBI ptt file) compare
SO3323 +1.3 5.1 acetyltransferase, GNAT family (NCBI ptt file) compare
SO3030 alcA +1.3 6.2 siderophore biosynthesis protein (NCBI ptt file) compare
SO2907 +1.3 7.3 TonB-dependent receptor domain protein (NCBI ptt file) compare
SO3256 +1.3 2.0 conserved hypothetical protein (NCBI ptt file) compare
SO0051 +1.3 1.8 hypothetical protein (NCBI ptt file) compare
SO0451 +1.2 1.2 hypothetical protein (NCBI ptt file) compare
SO2562 +1.2 4.8 conserved hypothetical protein (NCBI ptt file) compare
SO3241 flgJ +1.2 4.4 flagellar protein FlgJ (NCBI ptt file) compare
SO2766 +1.2 4.3 conserved hypothetical protein (NCBI ptt file) compare
SO3121 +1.2 3.9 conserved hypothetical protein (NCBI ptt file) compare
SO3258 +1.2 4.5 conserved hypothetical protein (NCBI ptt file) compare
SO4491 +1.2 2.2 hypothetical protein (NCBI ptt file) compare
SO_0887 +1.2 3.8 agmatine deiminase (RefSeq) compare
SO0132 +1.2 3.2 flagellar protein FliL, putative (NCBI ptt file) compare
SO1393 +1.2 3.8 transcriptional regulator, TetR family (NCBI ptt file) compare
SO3151 +1.2 4.0 conserved hypothetical protein (NCBI ptt file) compare
SO1617 +1.2 2.2 conserved hypothetical protein (NCBI ptt file) compare
SO1896 pccB-1 +1.2 4.3 3-methylcrotonyl CoA carboxylase, beta subunit (NCBI ptt file) compare
SO0320 +1.2 6.0 conserved domain protein (NCBI ptt file) compare
SO4163 hslU +1.2 3.9 heat shock protein HslVU, ATPase subunit HslU (NCBI ptt file) compare
SO2759 upp +1.2 2.8 uracil phosphoribosyltransferase (NCBI ptt file) compare
SO0272 cinA +1.2 5.2 competence/damage-inducible protein CinA (NCBI ptt file) compare
SO1848 +1.2 2.9 hypothetical protein (NCBI ptt file) compare
SO2862 +1.2 4.1 HDIG domain protein (NCBI ptt file) compare
SO2714 +1.2 1.1 hypothetical protein (NCBI ptt file) compare
SO4719 +1.2 4.7 conserved hypothetical protein (NCBI ptt file) compare
SO4519 +1.2 3.9 sodium-dependent transporter (NCBI ptt file) compare
SO1913 +1.2 3.3 conserved hypothetical protein (NCBI ptt file) compare
SO_4181 +1.2 4.2 no description compare
SO3011 +1.2 2.6 hypothetical protein (NCBI ptt file) compare
SO2381 +1.2 1.0 hypothetical protein (NCBI ptt file) compare
SO0797 +1.2 3.2 hypothetical protein (NCBI ptt file) compare
SO3066 +1.2 3.0 conserved hypothetical protein (NCBI ptt file) compare
SO3982 narP +1.1 2.1 DNA-binding nitrate/nitrite response regulator (NCBI ptt file) compare
SO2563 +1.1 4.1 metallo-beta-lactamase family protein (NCBI ptt file) compare
SO1530 pomB +1.1 3.8 sodium-driven polar flagellar protein PomB (NCBI ptt file) compare
SO3224 fliJ +1.1 2.3 flagellar protein FliJ (NCBI ptt file) compare
SO4509 +1.1 7.7 formate dehydrogenase, alpha subunit (NCBI ptt file) compare
SO2179 +1.1 1.8 hypothetical protein (NCBI ptt file) compare
SO3257 +1.1 2.1 conserved hypothetical protein (NCBI ptt file) compare
SO_3098 +1.1 1.2 no description compare
SO1673 +1.1 3.3 outer membrane protein OmpW, putative (NCBI ptt file) compare
SO2489 zwf +1.1 1.3 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) compare
SO0563 +1.1 1.1 hypothetical protein (NCBI ptt file) compare
SO0636 +1.1 1.8 acetyltransferase, GNAT family (NCBI ptt file) compare
SO3205 +1.1 2.5 hypothetical protein (NCBI ptt file) compare
SO4452 moaA +1.1 4.3 molybdenum cofactor biosynthesis protein A (NCBI ptt file) compare
SO3242 flgI +1.1 4.2 flagellar P-ring protein FlgI (NCBI ptt file) compare
SO0059 kdpE +1.1 2.7 transcriptional regulatory protein KdpE (NCBI ptt file) compare
SO3417 slyD +1.1 1.3 peptidyl-prolyl cis-trans isomerase SlyD (NCBI ptt file) compare
SO3921 hydB +1.1 1.1 periplasmic Fe hydrogenase, small subunit (NCBI ptt file) compare
SO4505 +1.1 5.3 conserved hypothetical protein (NCBI ptt file) compare
SO1222 +1.1 1.8 hypothetical protein (NCBI ptt file) compare


Specific Phenotypes

For 47 genes in this experiment

For carbon source L-Isoleucine in Shewanella oneidensis MR-1

For carbon source L-Isoleucine across organisms