Experiment set3H24 for Pseudomonas stutzeri RCH2

Compare to:

LB with sodium fluoride 6.25 mM

200 most important genes:

  gene name fitness t score description  
Psest_2035 -7.3 -7.1 crcB protein conserved
Psest_1492 -4.9 -4.8 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_2037 -4.2 -8.8 uroporphyrin-III C-methyltransferase compare
Psest_0062 -4.0 -10.4 tryptophan synthase, alpha subunit compare
Psest_2088 -3.8 -3.5 Uncharacterized protein conserved in bacteria compare
Psest_0063 -3.6 -6.1 tryptophan synthase, beta subunit compare
Psest_0280 -3.6 -15.0 homoserine O-acetyltransferase compare
Psest_2578 -3.5 -15.9 O-succinylhomoserine sulfhydrylase compare
Psest_0279 -3.2 -7.5 methionine biosynthesis protein MetW compare
Psest_2862 -3.1 -11.7 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_2034 -3.0 -5.7 ATPase related to the helicase subunit of the Holliday junction resolvase conserved
Psest_2872 -3.0 -2.9 protein RecA compare
Psest_1031 -3.0 -9.9 Uncharacterized protein conserved in bacteria compare
Psest_3338 -2.9 -2.7 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_3862 -2.9 -15.9 phosphoenolpyruvate-protein phosphotransferase compare
Psest_1704 -2.7 -2.6 Dehydrogenases (flavoproteins) compare
Psest_2714 -2.7 -3.1 7-cyano-7-deazaguanine reductase compare
Psest_1452 -2.7 -9.2 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_3647 -2.7 -6.7 Indole-3-glycerol phosphate synthase compare
Psest_3129 -2.7 -2.8 tyrosine recombinase XerD compare
Psest_1947 -2.6 -4.1 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2104 -2.5 -4.4 IscR-regulated protein YhgI compare
Psest_4219 -2.5 -1.7 DNA polymerase I compare
Psest_1765 -2.4 -9.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0958 -2.4 -11.0 Oligoketide cyclase/lipid transport protein compare
Psest_1012 -2.4 -6.9 Signal transduction histidine kinase compare
Psest_2090 -2.4 -5.6 Protein of unknown function (DUF2970). compare
Psest_2011 -2.4 -10.4 Predicted permease compare
Psest_3092 -2.4 -2.7 ribonuclease III, bacterial compare
Psest_3480 -2.4 -2.2 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_2584 -2.3 -9.5 Phosphoribosylanthranilate isomerase compare
Psest_1496 -2.3 -1.5 Holliday junction DNA helicase, RuvA subunit compare
Psest_1724 -2.3 -3.8 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0498 -2.2 -2.9 ribosome small subunit-dependent GTPase A compare
Psest_3449 -2.2 -1.4 DJ-1 family protein compare
Psest_0313 -2.2 -5.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_2933 -2.2 -12.8 Signal transduction histidine kinase compare
Psest_0445 -2.1 -15.4 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3767 -2.1 -4.4 tyrosine recombinase XerC compare
Psest_2863 -2.1 -7.0 Transcriptional regulator compare
Psest_2651 -2.1 -4.3 DNA topoisomerase I, bacterial compare
Psest_0542 -2.1 -7.4 AMP nucleosidase compare
Psest_0359 -2.1 -2.2 Transcriptional regulators compare
Psest_3720 -2.1 -14.8 penicillin-binding protein, 1A family compare
Psest_1505 -2.0 -2.8 Organic radical activating enzymes compare
Psest_3123 -2.0 -5.6 dihydroorotase, homodimeric type compare
Psest_4274 -2.0 -3.6 hypothetical protein compare
Psest_3998 -2.0 -4.1 glutamate--cysteine ligase compare
Psest_1750 -1.9 -2.9 Protein of unknown function (DUF2802). compare
Psest_3476 -1.9 -1.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0193 -1.9 -1.6 conserved hypothetical protein compare
Psest_3745 -1.8 -3.6 Uncharacterized enzyme of heme biosynthesis compare
Psest_4335 -1.8 -3.9 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_2333 -1.8 -1.8 Protein of unknown function (DUF3359). compare
Psest_4315 -1.8 -2.3 ABC-type metal ion transport system, permease component compare
Psest_4191 -1.8 -2.3 Transcriptional regulator compare
Psest_1111 -1.7 -3.9 Flp pilus assembly protein TadD, contains TPR repeats compare
Psest_3648 -1.7 -8.2 anthranilate phosphoribosyltransferase compare
Psest_0218 -1.7 -3.5 Acyl-CoA hydrolase compare
Psest_2923 -1.7 -2.1 hypothetical protein compare
Psest_4001 -1.7 -4.1 acetylornithine deacetylase (ArgE) compare
Psest_3790 -1.7 -7.0 Cytochrome c5 compare
Psest_2667 -1.7 -2.6 Uncharacterized protein involved in propionate catabolism compare
Psest_3047 -1.6 -2.0 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_3732 -1.6 -7.8 polyphosphate kinase 1 compare
Psest_3477 -1.6 -3.4 Signal transduction histidine kinase compare
Psest_3228 -1.6 -11.1 Zn-dependent protease with chaperone function compare
Psest_3118 -1.6 -8.4 endonuclease III compare
Psest_0064 -1.6 -1.5 Transcriptional regulator compare
Psest_0998 -1.6 -3.9 poly(A) polymerase compare
Psest_0408 -1.6 -3.8 Protein involved in catabolism of external DNA compare
Psest_1163 -1.6 -4.1 diguanylate cyclase (GGDEF) domain compare
Psest_3766 -1.6 -3.0 Uncharacterized protein conserved in bacteria compare
Psest_4124 -1.5 -4.2 hypothetical protein compare
Psest_1486 -1.5 -3.4 hypothetical protein compare
Psest_3339 -1.5 -5.1 Signal transduction histidine kinase compare
Psest_1525 -1.5 -5.9 Uncharacterized protein conserved in bacteria compare
Psest_2324 -1.5 -10.9 hypothetical protein compare
Psest_3458 -1.4 -1.4 hypothetical protein compare
Psest_2218 -1.4 -3.2 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit compare
Psest_2323 -1.4 -9.4 Uncharacterized protein conserved in archaea compare
Psest_0846 -1.4 -3.5 Uncharacterized protein probably involved in high-affinity Fe2+ transport compare
Psest_2229 -1.4 -3.2 Uncharacterized protein conserved in bacteria compare
Psest_3222 -1.4 -2.9 Putative threonine efflux protein compare
Psest_0508 -1.4 -6.5 gamma-glutamyl phosphate reductase compare
Psest_1242 -1.4 -2.6 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_0393 -1.4 -5.3 Methylase of chemotaxis methyl-accepting proteins compare
Psest_3884 -1.3 -0.8 Signal transduction histidine kinase compare
Psest_0309 -1.3 -1.7 RND family efflux transporter, MFP subunit compare
Psest_0165 -1.3 -3.7 protein-export chaperone SecB compare
Psest_2527 -1.3 -6.7 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_2946 -1.3 -4.5 septum site-determining protein MinD compare
Psest_3173 -1.3 -5.5 Uncharacterized protein conserved in bacteria compare
Psest_3317 -1.3 -5.3 Phosphotransferase System HPr (HPr) Family compare
Psest_1516 -1.3 -3.4 Uncharacterized lipoprotein compare
Psest_2362 -1.3 -6.1 Zn-dependent hydrolases, including glyoxylases compare
Psest_4044 -1.3 -6.8 type I site-specific deoxyribonuclease, HsdR family compare
Psest_0662 -1.2 -1.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4132 -1.2 -3.4 alpha-ketoglutarate DNA-binding response regulator (mifR) (from data) compare
Psest_3810 -1.2 -3.3 orotate phosphoribosyltransferase compare
Psest_0367 -1.2 -1.7 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_0133 -1.2 -1.5 type VI secretion protein, VC_A0107 family compare
Psest_3650 -1.2 -8.4 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0462 -1.2 -11.2 Lipid A core - O-antigen ligase and related enzymes compare
Psest_1506 -1.2 -5.1 queuosine biosynthesis protein QueC compare
Psest_2325 -1.2 -6.9 alpha-L-glutamate ligase-related protein compare
Psest_1022 -1.2 -6.4 Thiol:disulfide interchange protein compare
Psest_3247 -1.2 -2.3 Uncharacterized membrane protein compare
Psest_2334 -1.2 -9.0 Uncharacterized protein conserved in bacteria compare
Psest_2232 -1.2 -5.0 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_2764 -1.2 -1.4 hypothetical protein compare
Psest_2967 -1.2 -3.1 flagellar basal-body rod protein FlgC compare
Psest_4220 -1.2 -3.6 Protein of unknown function (DUF2782). compare
Psest_1563 -1.2 -2.1 Protein of unknown function (DUF548). compare
Psest_1884 -1.2 -2.2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_3322 -1.1 -9.0 TIGR02099 family protein compare
Psest_1535 -1.1 -1.9 FKBP-type peptidyl-prolyl cis-trans isomerases 1 compare
Psest_1295 -1.1 -6.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0734 -1.1 -1.9 RND family efflux transporter, MFP subunit compare
Psest_3085 -1.1 -5.3 methyltransferase, putative compare
Psest_2682 -1.1 -3.6 fumarate hydratase, class II compare
Psest_0417 -1.1 -3.5 Acyl-CoA dehydrogenases compare
Psest_2411 -1.1 -4.7 PAS domain S-box compare
Psest_0489 -1.1 -2.5 phosphoserine phosphatase SerB compare
Psest_4057 -1.1 -2.9 Peroxiredoxin compare
Psest_1103 -1.1 -3.1 GTP-binding protein YchF compare
Psest_0093 -1.1 -1.6 Uncharacterized enzyme of phosphonate metabolism compare
Psest_3070 -1.1 -2.2 3-oxoadipyl-CoA thiolase compare
Psest_1447 -1.1 -3.1 Putative threonine efflux protein compare
Psest_1885 -1.1 -2.6 hypothetical protein compare
Psest_0869 -1.1 -2.1 Acetyltransferase (isoleucine patch superfamily) compare
Psest_0146 -1.1 -5.9 Uncharacterized protein involved in outer membrane biogenesis compare
Psest_3384 -1.1 -6.2 glutamate 5-kinase compare
Psest_3084 -1.1 -1.8 methyltransferase, putative compare
Psest_3788 -1.1 -2.1 xanthine phosphoribosyltransferase compare
Psest_3479 -1.1 -2.3 molybdenum cofactor synthesis domain compare
Psest_4078 -1.1 -1.9 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_3890 -1.1 -1.1 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_0851 -1.0 -5.3 Transcriptional regulators compare
Psest_0844 -1.0 -4.3 High-affinity Fe2+/Pb2+ permease compare
Psest_2530 -1.0 -4.8 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_3842 -1.0 -2.7 Transcriptional regulators compare
Psest_1562 -1.0 -1.7 Uncharacterized protein conserved in bacteria compare
Psest_0652 -1.0 -2.4 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components compare
Psest_2768 -1.0 -2.3 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_1241 -1.0 -5.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Psest_1601 -1.0 -1.4 Signal transduction histidine kinase compare
Psest_3231 -1.0 -2.1 hypothetical protein compare
Psest_2924 -1.0 -3.4 Short-chain alcohol dehydrogenase of unknown specificity compare
Psest_3777 -1.0 -2.2 diguanylate cyclase (GGDEF) domain compare
Psest_1640 -1.0 -7.1 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_2119 -1.0 -2.3 Glycine/D-amino acid oxidases (deaminating) compare
Psest_2810 -1.0 -3.9 5'/3'-nucleotidase SurE compare
Psest_2120 -1.0 -1.3 Transcriptional regulator compare
Psest_1792 -0.9 -2.9 RND family efflux transporter, MFP subunit compare
Psest_1602 -0.9 -1.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1509 -0.9 -5.7 quinolinate synthetase complex, A subunit compare
Psest_3780 -0.9 -2.2 Transcriptional regulator compare
Psest_3090 -0.9 -5.0 DNA repair protein RecO compare
Psest_3691 -0.9 -3.5 Predicted membrane protein compare
Psest_1510 -0.9 -3.6 Putative Zn-dependent protease, contains TPR repeats compare
Psest_3883 -0.9 -3.7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1893 -0.9 -3.9 glucokinase, proteobacterial type compare
Psest_1979 -0.9 -2.8 Nucleotidyltransferase/DNA polymerase involved in DNA repair compare
Psest_0390 -0.9 -1.6 Short-chain dehydrogenases of various substrate specificities compare
Psest_4393 -0.9 -3.8 Capsule polysaccharide export protein compare
Psest_3649 -0.9 -5.5 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3494 -0.9 -1.6 hypothetical protein compare
Psest_3524 -0.9 -3.4 ribose-phosphate pyrophosphokinase compare
Psest_1790 -0.9 -3.4 ABC-type antimicrobial peptide transport system, ATPase component compare
Psest_0484 -0.9 -3.0 hypothetical protein compare
Psest_0257 -0.9 -3.0 Predicted Zn-dependent peptidases compare
Psest_3739 -0.9 -3.4 Small-conductance mechanosensitive channel compare
Psest_0537 -0.9 -1.3 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_1361 -0.9 -3.2 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_3519 -0.9 -2.4 Uncharacterized conserved protein compare
Psest_0691 -0.9 -6.3 ribonuclease R compare
Psest_0187 -0.9 -2.2 Metal-dependent hydrolase compare
Psest_2545 -0.9 -2.9 recombination protein RecR compare
Psest_0181 -0.9 -3.9 glycine cleavage system T protein compare
Psest_1013 -0.9 -2.7 phosphoribosylamine--glycine ligase compare
Psest_0168 -0.9 -4.0 Uncharacterized conserved protein compare
Psest_3894 -0.9 -2.7 Carbon starvation protein, predicted membrane protein compare
Psest_4109 -0.9 -2.5 selenocysteine-specific elongation factor SelB compare
Psest_2532 -0.9 -3.0 Uncharacterized protein conserved in bacteria compare
Psest_2564 -0.9 -4.0 NAD(P)H:quinone oxidoreductase, type IV compare
Psest_2457 -0.9 -2.2 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_4298 -0.9 -0.8 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_4247 -0.9 -1.6 Serine/threonine protein phosphatase compare
Psest_4097 -0.8 -5.6 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_2945 -0.8 -1.3 septum site-determining protein MinC compare
Psest_0868 -0.8 -3.6 Glutathione S-transferase compare
Psest_4164 -0.8 -3.0 flagellar biosynthetic protein FliS compare
Psest_0663 -0.8 -3.2 PAS fold. compare
Psest_3966 -0.8 -5.6 Predicted thioesterase compare
Psest_1574 -0.8 -2.0 phenazine biosynthesis protein PhzF family compare
Psest_2590 -0.8 -1.3 3-isopropylmalate dehydratase, small subunit compare
Psest_2809 -0.8 -1.9 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_1692 -0.8 -5.1 conserved hypothetical protein, YceG family compare
Psest_3882 -0.8 -5.1 Opacity protein and related surface antigens compare


Specific Phenotypes

For 6 genes in this experiment

For stress sodium fluoride in Pseudomonas stutzeri RCH2

For stress sodium fluoride across organisms