Experiment set3H23 for Shewanella oneidensis MR-1

Compare to:

L-Isoleucine carbon source replicate 2

200 most important genes:

  gene name fitness t score description  
SO1655 cysQ-2 -6.7 -3.7 cysQ protein (NCBI ptt file) compare
SO1265 -6.6 -4.3 transcriptional regulator, putative (NCBI ptt file) compare
SO2071 hisB -6.3 -4.4 imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase (NCBI ptt file) compare
SO_3457 -6.3 -6.1 hybrid sensory histidine kinase BarA (RefSeq) compare
SO2073 hisD -6.3 -4.3 histidinol dehydrogenase (NCBI ptt file) compare
SO4311 cyaY -6.2 -3.9 cyay protein (NCBI ptt file) compare
SO3414 thrB -6.1 -4.2 homoserine kinase (NCBI ptt file) compare
SO2070 hisH -6.1 -5.9 amidotransferase HisH (NCBI ptt file) compare
SO3986 lysC -6.1 -5.9 aspartokinase III, lysine-sensitive (NCBI ptt file) compare
SO1676 metA -6.0 -4.2 homoserine O-succinyltransferase (NCBI ptt file) compare
SO4054 metF -6.0 -5.9 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) compare
SO3554 purE -6.0 -4.1 phosphoribosylaminoimidazole carboxylase, catalytic subunit (NCBI ptt file) compare
SO2760 purM -6.0 -4.1 phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) compare
SO2074 hisG -5.9 -4.1 ATP phosphoribosyltransferase (NCBI ptt file) compare
SO0611 sspA -5.9 -4.1 stringent starvation protein a (NCBI ptt file) compare
SO1484 aceA -5.9 -8.0 Isocitrate lyase (EC 4.1.3.1) (from data) compare
SO3767 -5.9 -4.0 hypothetical protein (NCBI ptt file) compare
SO2333 -5.9 -5.7 hydrolase, alpha/beta fold family (NCBI ptt file) compare
SO0276 argB -5.8 -4.0 acetylglutamate kinase (NCBI ptt file) compare
SO0279 argH -5.8 -4.0 argininosuccinate lyase (NCBI ptt file) compare
SO4235 leuB -5.8 -4.0 3-isopropylmalate dehydrogenase (NCBI ptt file) compare
SO2638 ldh -5.8 -4.0 leucine dehydrogenase (NCBI ptt file) compare
SO0278 argG -5.8 -4.0 argininosuccinate synthase (NCBI ptt file) compare
SO0344 prpC -5.7 -5.6 2-methylcitrate synthase (EC 2.3.3.5) (from data) conserved
SO0275 argC -5.7 -6.8 N-acetyl-gamma-glutamyl-phosphate reductase (NCBI ptt file) compare
SO3555 purK -5.7 -5.6 phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) compare
SO1860 -5.7 -5.5 DNA-binding response regulator, LuxR family (NCBI ptt file) compare
SO0274 ppc -5.7 -5.5 phosphoenolpyruvate carboxylase (NCBI ptt file) compare
SO2339 -5.7 -5.5 alpha keto acid dehydrogenase complex, E1 component, alpha subunit (NCBI ptt file) compare
SO0862 serA -5.7 -5.5 D-3-phosphoglycerate dehydrogenase (NCBI ptt file) compare
SO3019 trpE -5.7 -3.9 anthranilate synthase component I (NCBI ptt file) compare
SO2280 -5.7 -5.5 bicyclomycin resistance protein (NCBI ptt file) compare
SO4345 ilvD -5.6 -3.9 dihydroxy-acid dehydratase (NCBI ptt file) compare
SO4056 metB -5.6 -3.9 cystathionine gamma-synthase (NCBI ptt file) compare
SO3413 thrC -5.6 -3.9 threonine synthase (NCBI ptt file) compare
SO4255 pyrE -5.6 -3.9 orotate phosphoribosyltransferase (NCBI ptt file) compare
SO1142 carB -5.6 -5.5 carbamoyl-phosphate synthase, large subunit (NCBI ptt file) compare
SO3737 cysI -5.6 -5.4 sulfite reductase (NADPH) hemoprotein beta-component (cysI) (NCBI ptt file) compare
SO3816 -5.6 -3.5 conserved hypothetical protein (NCBI ptt file) compare
SO0781 gcvP -5.5 -5.4 glycine cleavage system P protein (NCBI ptt file) compare
SO3695 pyrC -5.5 -3.8 dihydroorotase, homodimeric type (NCBI ptt file) compare
SO0287 aroB -5.5 -3.8 3-dehydroquinate synthase (NCBI ptt file) compare
SO0870 panB -5.5 -3.4 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) compare
SO1531 thiI -5.5 -5.4 thiamine biosynthesis protein ThiI (NCBI ptt file) compare
SO0340 ilvE -5.5 -3.8 branched-chain amino acid aminotransferase (NCBI ptt file) compare
SO1678 mmsA -5.5 -3.8 methylmalonate-semialdehyde dehydrogenase (NCBI ptt file) compare
SO0442 purH -5.5 -3.8 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) compare
SO1324 gltD -5.5 -3.8 glutamate synthase, small subunit (NCBI ptt file) compare
SO3726 cysN -5.5 -3.8 sulfate adenylyltransferase, subunit 1 (NCBI ptt file) compare
SO1679 -5.5 -5.3 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) conserved
SO3144 etfA -5.4 -3.8 electron transfer flavoprotein, alpha subunit (NCBI ptt file) compare
SO1794 clpP -5.4 -3.0 ATP-dependent Clp protease, proteolytic subunit (NCBI ptt file) compare
SO_1206 -5.4 -3.7 no description compare
SO4233 leuD -5.4 -3.7 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) compare
SO1141 carA -5.4 -5.3 carbamoyl-phosphate synthase, small subunit (NCBI ptt file) compare
SO3641 apaH -5.4 -3.7 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) (NCBI ptt file) compare
SO3363 -5.4 -3.7 transcriptional regulator, LysR family (NCBI ptt file) compare
SO3435 surE -5.4 -3.7 stationary-phase survival protein SurE (NCBI ptt file) compare
SO3817 panE -5.4 -6.4 2-dehydropantoate 2-reductase (NCBI ptt file) compare
SO3455 relA -5.4 -3.7 GTP pyrophosphokinase (NCBI ptt file) compare
SO1325 gltB -5.4 -5.2 glutamate synthase, large subunit (NCBI ptt file) compare
SO0831 gshB -5.4 -3.7 glutathione synthetase (NCBI ptt file) compare
SO4349 ilvC -5.3 -7.3 ketol-acid reductoisomerase (NCBI ptt file) compare
SO3740 pntA -5.3 -3.7 NAD(P) transhydrogenase, alpha subunit (NCBI ptt file) compare
SO_1223 serB -5.3 -5.2 phosphoserine phosphatase (RefSeq) compare
SO4462 -5.3 -6.3 hypothetical protein (NCBI ptt file) compare
SO3741 pntB -5.3 -3.7 NAD(P) transhydrogenase, beta subunit (NCBI ptt file) compare
SO4066 -5.3 -5.2 phosphoribosylaminoimidazole-succinocarboxamide synthase, putative (NCBI ptt file) compare
SO3145 etfB -5.3 -6.3 electron transfer flavoprotein, beta subunit (NCBI ptt file) compare
SO0818 metE -5.3 -6.3 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) compare
SO4488 -5.3 -6.3 sensor histidine kinase (NCBI ptt file) compare
SO3020 trpG -5.2 -3.6 glutamine amido-transferase (NCBI ptt file) compare
SO1122 proA -5.2 -5.1 gamma-glutamyl phosphate reductase (NCBI ptt file) compare
SO0277 argF -5.2 -5.1 ornithine carbamoyltransferase (NCBI ptt file) compare
SO4350 ilvY -5.2 -5.1 transcriptional regulator ilvY (NCBI ptt file) compare
SO2045 -5.2 -3.6 cation efflux family protein (NCBI ptt file) compare
SO3023 trpB -5.2 -5.1 tryptophan synthase, beta subunit (NCBI ptt file) compare
SO2340 -5.2 -8.7 alpha keto acid dehydrogenase complex, E1 component, beta subunit (NCBI ptt file) compare
SO1121 proB -5.2 -5.1 glutamate 5-kinase (NCBI ptt file) compare
SO2398 pyrF -5.2 -4.9 orotidine 5`-phosphate decarboxylase (NCBI ptt file) compare
SO4453 -5.2 -3.6 electron transfer flavoprotein-ubiquinone oxidoreductase, putative (NCBI ptt file) compare
SO2592 pyrD -5.2 -5.0 dihydroorotate dehydrogenase (NCBI ptt file) compare
SO4309 lysA -5.1 -6.1 diaminopimelate decarboxylase (NCBI ptt file) compare
SO0617 argD -5.1 -5.0 acetylornithine aminotransferase (NCBI ptt file) compare
SO2068 hisF -5.1 -5.0 hisF protein (cyclase) (NCBI ptt file) compare
SO1677 atoB -5.1 -3.5 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) (from data) conserved
SO2191 metC -5.1 -3.5 cystathionine beta-lyase (NCBI ptt file) compare
SO3022 trpC/F -5.1 -3.5 indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (NCBI ptt file) compare
SO0040 aroE -5.1 -5.0 shikimate 5-dehydrogenase (NCBI ptt file) compare
SO2069 hisA -5.1 -3.5 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (NCBI ptt file) compare
SO3078.2 -5.1 -3.5 hypothetical chorismate synthase (NCBI ptt file) compare
SO0779 gcvT -5.1 -6.1 glycine cleavage system T protein (NCBI ptt file) compare
SO0345 prpB -5.1 -3.5 methylisocitrate lyase (NCBI ptt file) compare
SO4648 -5.1 -4.9 sensor histidine kinase (NCBI ptt file) compare
SO3287 purL -5.1 -6.9 phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
SO0346 -5.0 -3.5 transcriptional regulator. GntR family (NCBI ptt file) compare
SO3354 proC -5.0 -4.9 pyrroline-5-carboxylate reductase (NCBI ptt file) compare
SO4234 leuC -5.0 -3.5 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) compare
SO3021 trpD -5.0 -3.5 anthranilate phosphoribosyltransferase (NCBI ptt file) compare
SO1878 -5.0 -3.4 glycine cleavage system transcriptional repressor, putative (NCBI ptt file) compare
SO3415 thrA -5.0 -13.6 aspartokinase I/homoserine dehydrogenase, threonine-sensitive (NCBI ptt file) compare
SO0878 prkB -5.0 -3.4 phosphoribulokinase (NCBI ptt file) compare
SO2406 aspC-2 -5.0 -4.8 aspartate aminotransferase (NCBI ptt file) compare
SO1680 -5.0 -3.4 enoyl-CoA hydratase/isomerase family protein (NCBI ptt file) compare
SO1362 tyrA -5.0 -4.8 chorismate mutase/prephenate dehydrogenase (NCBI ptt file) compare
SO2279 ilvI -5.0 -3.4 acetolactate synthase III, large subunit (NCBI ptt file) compare
SO4674 kbl -5.0 -10.6 2-amino-3-ketobutyrate coenzyme A ligase (NCBI ptt file) compare
SO3024 trpA -5.0 -4.8 tryptophan synthase, alpha subunit (NCBI ptt file) compare
SO2767 asnB-1 -4.9 -3.4 asparagine synthetase B, glutamine-hydrolyzing (NCBI ptt file) compare
SO0942 -4.9 -6.7 conserved hypothetical protein (NCBI ptt file) compare
SO2903 cysK -4.9 -3.4 cysteine synthase A (NCBI ptt file) compare
SO1681 -4.9 -4.8 enoyl-CoA hydratase/isomerase family protein (NCBI ptt file) compare
SO2341 -4.9 -3.4 alpha keto acid dehydrogenase complex, E2 component (NCBI ptt file) compare
SO3728 cobA -4.9 -3.4 uroporphyrin-III C-methyltransferase (NCBI ptt file) compare
SO3727 cysD -4.9 -4.7 sulfate adenylyltransferase, subunit 2 (NCBI ptt file) compare
SO0441 purD -4.9 -6.7 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
SO4672 glpE -4.9 -4.4 glpE protein (NCBI ptt file) compare
SO4236 leuA -4.8 -8.0 2-isopropylmalate synthase (NCBI ptt file) compare
SO4429 -4.8 -3.3 hypothetical protein (NCBI ptt file) compare
SO1275 gabD -4.8 -8.0 succinate-semialdehyde dehydrogenase (NADP+) [EC: 1.2.1.16] (from data) compare
SO3108 -4.8 -3.0 siroheme synthase, N-terminal component, putative (NCBI ptt file) compare
SO2493 -4.8 -3.3 transcriptional regulator, TetR family (NCBI ptt file) compare
SO1669 tyrR -4.8 -6.5 transcriptional regulatory protein TyrR (NCBI ptt file) compare
SO4245 argA -4.7 -4.6 amino-acid acetyltransferase (NCBI ptt file) compare
SO1071 -4.7 -5.6 conserved hypothetical protein (NCBI ptt file) compare
SO2648 -4.7 -11.3 DNA-binding response regulator, LuxR family (NCBI ptt file) compare
SO0512 aroQ -4.7 -3.3 3-dehydroquinate dehydratase, type II (NCBI ptt file) compare
SO1683 -4.7 -2.7 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) (from data) compare
SO3962 yfiA-3 -4.6 -2.9 ribosomal subunit interface protein (NCBI ptt file) compare
SO0428 -4.6 -17.7 conserved hypothetical protein (NCBI ptt file) compare
SO0977 -4.6 -3.2 transcriptional regulator, MarR family (NCBI ptt file) compare
SO4603 lexA -4.6 -3.2 LexA repressor (NCBI ptt file) compare
SO0817 metR -4.6 -6.3 transcriptional activator protein MetR (NCBI ptt file) compare
SO2072 hisC -4.6 -3.2 histidinol-phosphate aminotransferase (NCBI ptt file) compare
SO1270 -4.6 -6.9 polyamine ABC transporter, periplasmic polyamine-binding protein (NCBI ptt file) compare
SO2067 hisI -4.6 -2.9 phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase (NCBI ptt file) compare
SO3749 -4.6 -3.1 Acetylornithine deacetylase (EC:3.5.1.16) (from data) compare
SOA0057 -4.6 -1.5 hypothetical protein (NCBI ptt file) compare
SO1917 -4.5 -6.2 multidrug resistance protein, putative (NCBI ptt file) compare
SO0127 -4.5 -11.3 hypothetical protein (NCBI ptt file) compare
SO1946 phoP -4.5 -6.0 transcriptional regulatory protein PhoP (NCBI ptt file) compare
SO1570 -4.5 -13.3 GGDEF domain protein (NCBI ptt file) compare
SO0774 -4.4 -8.5 5-formyltetrahydrofolate cyclo-ligase family protein (NCBI ptt file) compare
SO2785 rne -4.4 -7.4 ribonuclease E (NCBI ptt file) compare
SO2649 cysB -4.4 -2.3 cys regulon transcriptional activator (NCBI ptt file) compare
SO3211 flhG -4.4 -3.0 flagellar biosynthetic protein FlhG (NCBI ptt file) compare
SO3064 purF -4.4 -3.0 amidophosphoribosyltransferase (NCBI ptt file) compare
SO3516 -4.4 -9.7 transcriptional regulator, LacI family (NCBI ptt file) compare
SO3799 asnC -4.4 -5.7 regulatory protein AsnC (NCBI ptt file) compare
SO3738 cysJ -4.4 -3.0 sulfite reductase (NADPH) flavoprotein alpha-component (NCBI ptt file) compare
SO3352 -4.4 -2.9 conserved hypothetical protein TIGR00044 (NCBI ptt file) compare
SO1985 -4.4 -4.2 transcriptional activator, putative (NCBI ptt file) compare
SO2404 aroA -4.4 -5.9 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI ptt file) compare
SO2627 -4.4 -1.9 conserved hypothetical protein (NCBI ptt file) compare
SO2359 -4.4 -3.0 cation transport ATPase, E1-E2 family (NCBI ptt file) compare
SO1355 -4.3 -5.9 membrane protein, putative (NCBI ptt file) compare
SO2626 clpA -4.3 -4.2 ATP-dependent Clp protease, ATP-binding subunit ClpA (NCBI ptt file) compare
SO3723 cysC -4.3 -2.9 adenylylsulfate kinase (NCBI ptt file) compare
SO4472 ntrC -4.3 -9.1 nitrogen regulation protein NR(I) (NCBI ptt file) compare
SO2712 -4.3 -5.8 hypothetical protein (NCBI ptt file) compare
SO1272 -4.3 -6.5 polyamine ABC transporter, permease protein (NCBI ptt file) compare
SO0780 gcvH -4.3 -4.2 glycine cleavage system H protein (NCBI ptt file) compare
SO1626 glnD -4.3 -8.1 protein-P-II uridylyltransferase (NCBI ptt file) compare
SO3715 -4.2 -9.9 oxygen-insensitive NAD(P)H nitroreductase (NCBI ptt file) compare
SO_3068 -4.2 -2.9 no description compare
SO_3079 -4.1 -1.8 no description compare
SO4364 recG -4.1 -10.6 ATP-dependent DNA helicase RecG (NCBI ptt file) compare
SO0408 gppA -4.1 -5.9 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (NCBI ptt file) compare
SO1292 folK-2 -4.1 -2.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (NCBI ptt file) compare
SO2361 ccoP -4.1 -2.8 cytochrome c oxidase, cbb3-type, subunit III (NCBI ptt file) compare
SO0342 -4.1 -2.8 conserved hypothetical protein (NCBI ptt file) compare
SO1795 clpX -4.1 -2.8 ATP-dependent Clp protease, ATP-binding subunit ClpX (NCBI ptt file) compare
SO2884 -4.1 -9.5 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
SO2644 ppsA -4.1 -2.8 phosphoenolpyruvate synthase (NCBI ptt file) compare
SO2342 nadA -4.0 -2.7 quinolinate synthetase complex, subunit A (NCBI ptt file) compare
SO0407 -4.0 -7.6 ATP-dependent RNA helicase, DEAD box family (NCBI ptt file) compare
SO2472 -4.0 -2.7 D-alanyl-D-alanine carboxypeptidase-related protein (NCBI ptt file) compare
SO2363 ccoO -4.0 -1.8 cytochrome c oxidase, cbb3-type, subunit II (NCBI ptt file) compare
SO3760 glnE -4.0 -15.7 glutamate-ammonia-ligase adenylyltransferase (NCBI ptt file) compare
SO1273 -4.0 -8.8 polyamine ABC transporter, permease protein (NCBI ptt file) compare
SO2615 pabC -4.0 -2.5 4-amino-4-deoxychorismate lyase (NCBI ptt file) compare
SO0421 ampD -3.9 -10.3 AmpD protein (NCBI ptt file) compare
SO3082 sixA -3.9 -2.7 phosphohistidine phosphatase SixA (NCBI ptt file) compare
SO0931 epd -3.9 -2.7 D-erythrose-4-phosphate dehydrogenase (NCBI ptt file) compare
SO0871 folK-1 -3.9 -1.2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (NCBI ptt file) compare
SO2588 -3.9 -5.9 protein-methionine-S-oxide reductase, PilB family (NCBI ptt file) compare
SO1301 pyrB -3.8 -5.2 aspartate carbamoyltransferase (NCBI ptt file) compare
SO3765 -3.8 -2.4 conserved hypothetical protein (NCBI ptt file) compare
SO0343 acnA -3.8 -2.6 aconitate hydratase 1 (NCBI ptt file) compare
SO3949 -3.7 -1.7 BolA/YrbA family protein (NCBI ptt file) compare
SO2743 acs -3.7 -6.6 acetyl-coenzyme A synthetase (NCBI ptt file) compare
SO1898 -3.7 -8.3 transcriptional regulator, putative (NCBI ptt file) compare
SO2616 dcd -3.7 -1.2 deoxycytidine triphosphate deaminase (NCBI ptt file) compare
SO0038 hemF -3.7 -3.6 coproporphyrinogen III oxidase, aerobic (NCBI ptt file) compare
SO4343 -3.7 -9.4 aminotransferase, class V (NCBI ptt file) compare
SO1483 aceB -3.7 -4.3 Malate synthase (EC 2.3.3.9) (from data) compare
SO0609 petB -3.7 -2.5 ubiquinol-cytochrome c reductase, cytochrome b (NCBI ptt file) compare
SO0943 -3.7 -11.6 sensory box protein, putative (NCBI ptt file) compare
SO2490 -3.6 -2.5 transcriptional regulator, RpiR family (NCBI ptt file) compare
SO2657 -3.6 -3.2 hypothetical protein (NCBI ptt file) compare


Specific Phenotypes

For 58 genes in this experiment

For carbon source L-Isoleucine in Shewanella oneidensis MR-1

For carbon source L-Isoleucine across organisms