Experiment set3H16 for Shewanella oneidensis MR-1

Compare to:

Sodium L-Lactate carbon source replicate 2

200 most detrimental genes:

  gene name fitness t score description  
SO1191 greA +3.6 13.8 transcription elongation factor GreA (NCBI ptt file) compare
SO1665 galU +3.5 19.1 UTP-glucose-1-phosphate uridylyltransferase (NCBI ptt file) compare
SO2472 +3.3 10.1 D-alanyl-D-alanine carboxypeptidase-related protein (NCBI ptt file) compare
SO2336 pgm +2.9 5.0 phosphoglucomutase, alpha-D-glucose phosphate-specific (NCBI ptt file) compare
SO0414 pilD +2.6 7.5 type 4 prepilin-like proteins leader peptide processing enzyme (NCBI ptt file) compare
SO3771 +2.5 7.9 phosphate transporter, putative (NCBI ptt file) compare
SO2238 ptsH +2.4 4.8 phosphocarrier protein HPr (NCBI ptt file) compare
SO2340 +2.3 16.4 alpha keto acid dehydrogenase complex, E1 component, beta subunit (NCBI ptt file) compare
SO2341 +2.3 15.8 alpha keto acid dehydrogenase complex, E2 component (NCBI ptt file) compare
SO2237 ptsI +2.2 7.0 phosphoenolpyruvate-protein phosphotransferase (NCBI ptt file) compare
SO2339 +2.2 14.2 alpha keto acid dehydrogenase complex, E1 component, alpha subunit (NCBI ptt file) compare
SO2537 +2.2 16.4 sodium/hydrogen exchanger family protein (NCBI ptt file) compare
SO2648 +2.0 13.6 DNA-binding response regulator, LuxR family (NCBI ptt file) compare
SO1679 +2.0 12.6 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
SO3770 +2.0 4.5 conserved hypothetical protein TIGR00153 (NCBI ptt file) compare
SO3144 etfA +1.9 11.5 electron transfer flavoprotein, alpha subunit (NCBI ptt file) compare
SO_3579 +1.9 6.7 no description compare
SO1678 mmsA +1.9 11.6 methylmalonate-semialdehyde dehydrogenase (NCBI ptt file) compare
SO3179 +1.8 15.9 lipopolysaccharide biosynthesis polymerase, putative (NCBI ptt file) compare
SO1343 rseA +1.8 3.0 sigma-E factor negative regulatory protein (NCBI ptt file) compare
SO2489 zwf +1.8 4.9 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) compare
SO2487 edd +1.8 3.5 6-phosphogluconate dehydratase (NCBI ptt file) compare
SO2742 +1.8 14.7 sensor histidine kinase/response regulator (NCBI ptt file) compare
SO2108 mdoH +1.8 11.5 periplasmic glucans biosynthesis protein MdoH (NCBI ptt file) compare
SO0263 ccmA +1.8 4.9 heme exporter protein CcmA (NCBI ptt file) compare
SO3745 rfaE +1.8 11.5 ADP-heptose synthase (NCBI ptt file) compare
SO3145 etfB +1.7 11.9 electron transfer flavoprotein, beta subunit (NCBI ptt file) compare
SO0267 dsbE +1.7 6.8 thiol:disulfide interchange protein DsbE (NCBI ptt file) compare
SO0266 ccmF-1 +1.7 10.8 cytochrome c-type biogenesis protein CcmF (NCBI ptt file) compare
SO4453 +1.7 12.4 electron transfer flavoprotein-ubiquinone oxidoreductase, putative (NCBI ptt file) compare
SO1344 rseB +1.6 4.9 sigma-E factor regulatory protein RseB (NCBI ptt file) compare
SO0268 ccmH +1.6 9.3 cytochrome c-type biogenesis protein CcmH (NCBI ptt file) compare
SO0261 ccmC +1.6 3.8 heme exporter protein CcmC (NCBI ptt file) compare
SO1210.1 +1.6 6.1 hypothetical peptide chain release factor 3 (NCBI ptt file) compare
SO1677 atoB +1.5 8.3 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) (from data) compare
SO0696 dsbD +1.5 9.5 thiol:disulfide interchange protein DsbD (NCBI ptt file) compare
SO4678 +1.5 11.9 heptosyl transferase, glycosyltransferase family 9 protein (NCBI ptt file) compare
SO0259 ccmE +1.5 3.6 cytochrome c biogenesis protein CcmE (NCBI ptt file) compare
SO1529 pomA +1.5 5.6 chemotaxis motA protein (NCBI ptt file) compare
SO3227 fliG +1.5 9.9 flagellar motor switch protein FliG (NCBI ptt file) compare
SO3954 +1.5 7.0 ABC transporter, ATP-binding protein, putative (NCBI ptt file) compare
SO0769 argR +1.4 4.8 arginine repressor (NCBI ptt file) compare
SO2774 fabF-1 +1.4 4.7 3-oxoacyl-(acyl-carrier-protein) synthase II (NCBI ptt file) compare
SO2602 +1.4 3.8 hypothetical Activator of ProP osmoprotectant transporter (NCBI ptt file) compare
SO_2754 +1.4 6.2 no description compare
SO2426 +1.3 3.8 DNA-binding response regulator (NCBI ptt file) compare
SO3953 +1.3 6.4 conserved hypothetical protein TIGR00056 (NCBI ptt file) compare
SO_1900 +1.3 9.6 no description compare
SO1818 +1.3 9.4 conserved hypothetical protein (NCBI ptt file) compare
SO2427 +1.3 8.2 TonB-dependent receptor, putative (NCBI ptt file) compare
SO0262 ccmB +1.3 3.7 heme exporter protein CcmB (NCBI ptt file) compare
SO1169 +1.3 7.0 conserved hypothetical protein TIGR00246 (NCBI ptt file) compare
SO4197 menG-2 +1.3 3.1 S-adenosylmethionine:2-demethylmenaquinone methyltransferase (NCBI ptt file) compare
SO3228 fliF +1.3 9.5 flagellar M-ring protein FliF (NCBI ptt file) compare
SO3245 flgF +1.3 8.7 flagellar basal-body rod protein FlgF (NCBI ptt file) compare
SO3210 fliA +1.3 4.6 RNA polymerase sigma-27 factor (NCBI ptt file) compare
SO0264 scyA +1.3 3.1 cytochrome c (NCBI ptt file) compare
SO4227 +1.2 1.9 conserved hypothetical protein TIGR00006 (NCBI ptt file) compare
SO2381 +1.2 2.1 hypothetical protein (NCBI ptt file) compare
SO3832 +1.2 5.9 hemK family protein (NCBI ptt file) compare
SO2887 dsbB +1.2 3.9 disulfide bond formation protein b (NCBI ptt file) compare
SO1938 cobB +1.2 7.5 cobB protein (NCBI ptt file) compare
SO1537 +1.2 2.7 hypothetical protein (NCBI ptt file) compare
SO3142.3 +1.2 3.4 hypothetical Na+/H+ antiporte (NCBI ptt file) compare
SO1014 nuoI +1.2 5.2 NADH dehydrogenase I, I subunit (NCBI ptt file) compare
SO1378 +1.2 2.4 ThiJ/PfpI family protein (NCBI ptt file) compare
SO3232 flrA +1.2 6.7 flagellar regulatory protein A (NCBI ptt file) compare
SO1669 tyrR +1.1 7.4 transcriptional regulatory protein TyrR (NCBI ptt file) compare
SO_1211 +1.1 5.8 no description compare
SO2738 bioC +1.1 1.5 biotin synthesis protein BioC (NCBI ptt file) compare
SO3249 flgC +1.1 4.5 flagellar basal-body rod protein FlgC (NCBI ptt file) compare
SO3181 +1.1 3.1 polysaccharide biosynthesis domain protein (NCBI ptt file) compare
SO1819 dinG +1.1 8.1 ATP-dependent helicase DinG (NCBI ptt file) compare
SO4094 cafA +1.1 5.7 ribonuclease G (NCBI ptt file) compare
SO0217 tufB +1.1 1.9 translation elongation factor Tu (NCBI ptt file) compare
SO3172 +1.1 2.9 galactosyl transferase (NCBI ptt file) compare
SO1107 nqrE-2 +1.1 3.7 NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE (NCBI ptt file) compare
SO0721 +1.1 5.8 conserved hypothetical protein (NCBI ptt file) compare
SO3250 flgB +1.1 6.1 flagellar basal-body rod protein FlgB (NCBI ptt file) compare
SO0169 gspG +1.1 4.3 general secretion pathway protein G (NCBI ptt file) compare
SO0208 +1.0 6.5 RNA-binding protein (NCBI ptt file) compare
SO3218 fliP +1.0 6.1 flagellar biosynthetic protein FliP (NCBI ptt file) compare
SO0293 gph +1.0 5.3 phosphoglycolate phosphatase (NCBI ptt file) compare
SO0359 spoT +1.0 2.3 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) compare
SO0702 +1.0 5.7 MATE efflux family protein (NCBI ptt file) compare
SO0175 gspM +1.0 2.8 general secretion pathway protein M (NCBI ptt file) compare
SO2422 +1.0 3.6 conserved hypothetical protein (NCBI ptt file) compare
SO3219 fliO +1.0 3.0 flagellar protein FliO (NCBI ptt file) compare
SO3215 flhB +1.0 5.5 flagellar biosynthetic protein FlhB (NCBI ptt file) compare
SO1683 +1.0 2.4 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) (from data) compare
SO0172 gspJ +1.0 4.6 general secretion pathway protein J (NCBI ptt file) compare
SO1530 pomB +1.0 4.8 sodium-driven polar flagellar protein PomB (NCBI ptt file) compare
SO2614 +1.0 3.0 conserved hypothetical protein TIGR00247 (NCBI ptt file) compare
SO3258 +1.0 7.1 conserved hypothetical protein (NCBI ptt file) compare
SO3887 +1.0 2.7 conserved hypothetical protein (NCBI ptt file) compare
SO3268 +1.0 7.6 alpha amylase domain protein (NCBI ptt file) compare
SO0167 gspE +1.0 6.7 general secretion pathway protein E (NCBI ptt file) compare
SO2638 ldh +1.0 5.8 leucine dehydrogenase (NCBI ptt file) compare
SO1016 nuoG +1.0 7.2 NADH dehydrogenase I, G subunit (NCBI ptt file) compare
SO0947 srmB +1.0 7.1 ATP-dependent RNA helicase SrmB (NCBI ptt file) compare
SO3952 +1.0 4.5 mce-related protein (NCBI ptt file) compare
SO0562 +1.0 1.3 hypothetical protein (NCBI ptt file) compare
SO3226 fliH +0.9 5.2 flagellar assembly protein FliH (NCBI ptt file) compare
SO1009 nuoN +0.9 5.8 NADH dehydrogenase I, N subunit (NCBI ptt file) compare
SO1878 +0.9 2.7 glycine cleavage system transcriptional repressor, putative (NCBI ptt file) compare
SO1105 nqrC-2 +0.9 2.1 NADH:ubiquinone oxidoreductase, Na translocating, gamma subunit (NCBI ptt file) compare
SO3244 flgG +0.9 6.3 flagellar basal-body rod protein FlgG (NCBI ptt file) compare
SO3352 +0.9 3.3 conserved hypothetical protein TIGR00044 (NCBI ptt file) compare
SO3417 slyD +0.9 4.0 peptidyl-prolyl cis-trans isomerase SlyD (NCBI ptt file) compare
SO3269 +0.9 6.4 cytidylyltransferase domain protein (NCBI ptt file) compare
SO0166 gspD +0.9 7.2 general secretion pathway protein D (NCBI ptt file) compare
SO4034 deaD +0.9 4.3 ATP-dependent RNA helicase DeaD (NCBI ptt file) compare
SO0229 tufA +0.9 1.5 translation elongation factor Tu (NCBI ptt file) compare
SO3562 +0.9 4.6 proton/glutamate symporter, putative (NCBI ptt file) compare
SO1011 nuoL +0.9 6.3 NADH dehydrogenase I, L subunit (NCBI ptt file) compare
SO2841 +0.9 2.7 hypothetical protein (NCBI ptt file) compare
SO2916 pta +0.9 6.2 phosphate acetyltransferase (NCBI ptt file) compare
SO_2605 +0.9 2.5 no description compare
SO2562 +0.9 5.0 conserved hypothetical protein (NCBI ptt file) compare
SO2872 +0.9 2.0 conserved hypothetical protein (NCBI ptt file) compare
SO1383 +0.9 4.1 ATP-dependent RNA helicase, DEAD box family (NCBI ptt file) compare
SO2491 pykA +0.8 1.5 pyruvate kinase II (NCBI ptt file) compare
SO3109 +0.8 3.4 conserved hypothetical protein (NCBI ptt file) compare
SO1313 +0.8 3.8 conserved hypothetical protein (NCBI ptt file) compare
SO2088 +0.8 1.2 lipid A biosynthesis acyltransferase, putative (NCBI ptt file) compare
SO2298 +0.8 1.1 hypothetical protein (NCBI ptt file) compare
SO0872 pcnB +0.8 4.5 polyA polymerase (NCBI ptt file) compare
SO3185 +0.8 7.1 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO3225 fliI +0.8 5.3 flagellum-specific ATP synthase FliI (NCBI ptt file) compare
SO4680 +0.8 5.5 conserved hypothetical protein (NCBI ptt file) compare
SO1790 ppiB-1 +0.8 2.5 peptidyl-prolyl cis-trans isomerase B (NCBI ptt file) compare
SO1010 nuoM +0.8 5.3 NADH dehydrogenase I, M subunit (NCBI ptt file) compare
SO3197 +0.8 4.2 vacJ lipoprotein, putative (NCBI ptt file) compare
SO2417 +0.8 2.7 iron-sulfur cluster-binding protein (NCBI ptt file) compare
SO4007 +0.8 2.4 predicted chromosome partitioning protein (with smc-like SO4008) (from data) compare
SO1017 nuoF +0.8 5.4 NADH dehydrogenase I, F subunit (NCBI ptt file) compare
SO3184 +0.8 7.4 conserved hypothetical protein (NCBI ptt file) compare
SO4248 radC +0.8 4.4 DNA repair protein RadC (NCBI ptt file) compare
SO2852 +0.8 2.8 transcriptional regulator, GntR family (NCBI ptt file) compare
SO1373 +0.8 3.5 conserved hypothetical protein (NCBI ptt file) compare
SO0173 gspK +0.8 3.2 general secretion pathway protein K (NCBI ptt file) compare
SO2838 +0.8 1.4 ATP-dependent RNA helicase, DEAD box family (NCBI ptt file) compare
SO4727 +0.8 3.6 conserved hypothetical protein (NCBI ptt file) compare
SO1021 nuoA +0.8 1.8 NADH dehydrogenase I, A subunit (NCBI ptt file) compare
SO3262 ilvB +0.8 6.2 acetolactate synthase isozyme I, large subunit (NCBI ptt file) compare
SO2628 cspD +0.8 3.0 stress response protein CspD (NCBI ptt file) compare
SO0165 gspC +0.8 4.1 general secretion pathway protein C (NCBI ptt file) compare
SO4687 ugd +0.8 5.8 UDP-glucose 6-dehydrogenase (NCBI ptt file) compare
SO4256 rph +0.8 2.2 ribonuclease PH (NCBI ptt file) compare
SO2248 sdaA +0.7 2.9 L-serine dehydratase 1 (NCBI ptt file) compare
SO1215 +0.7 4.4 outer membrane protein OmpK, putative (NCBI ptt file) compare
SO0168 gspF +0.7 4.6 general secretion pathway protein F (NCBI ptt file) compare
SO3265 +0.7 5.2 conserved hypothetical protein (NCBI ptt file) compare
SOA0085 +0.7 1.1 ISSod8, transposase (NCBI ptt file) compare
SO0170 gspH +0.7 2.8 general secretion pathway protein H (NCBI ptt file) compare
SO1846 +0.7 3.2 hypothetical protein (NCBI ptt file) compare
SO1012 nuoK +0.7 4.4 NADH dehydrogenase I, K subunit (NCBI ptt file) compare
SO0174 gspL +0.7 3.4 general secretion pathway protein L (NCBI ptt file) compare
SO4702 gor +0.7 6.1 glutathione reductase (NCBI ptt file) compare
SO2305 lrp +0.7 3.7 leucine-responsive regulatory protein (NCBI ptt file) compare
SO0556 +0.7 2.6 hypothetical protein (NCBI ptt file) compare
SO_A0174 +0.7 2.1 hypothetical protein (NCBI) compare
SO4351 +0.7 5.2 CBS domain protein (NCBI ptt file) compare
SO3242 flgI +0.7 3.9 flagellar P-ring protein FlgI (NCBI ptt file) compare
SO3062 +0.7 1.4 hypothetical protein (NCBI ptt file) compare
SO1759 +0.7 2.8 conserved hypothetical protein (NCBI ptt file) compare
SO3951 +0.7 2.1 conserved hypothetical protein (NCBI ptt file) compare
SO1664 galE +0.7 4.8 UDP-glucose 4-epimerase (NCBI ptt file) compare
SO2062 +0.7 2.3 conserved hypothetical protein (NCBI ptt file) compare
SO_3118 +0.7 2.1 no description compare
SO1015 nuoH +0.7 3.4 NADH dehydrogenase I, H subunit (NCBI ptt file) compare
SO3253 +0.7 4.9 flagellar basal-body P-ring formation protein FlgA, putative (NCBI ptt file) compare
SO4203 tatB +0.7 1.8 Sec-independent protein translocase protein TatB (NCBI ptt file) compare
SO0086 +0.7 1.6 hypothetical protein (NCBI ptt file) compare
SO2414 +0.7 3.3 phosphoglycolate phosphatase, putative (NCBI ptt file) compare
SO1020 nuoB +0.7 2.9 NADH dehydrogenase I, B subunit (NCBI ptt file) compare
SO0600 amiB +0.7 2.7 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
SO1314 +0.7 5.4 peptidase, M23/M37 family (NCBI ptt file) compare
SO1019 nuoCD +0.6 3.7 NADH dehydrogenase I, C/D subunits (NCBI ptt file) compare
SO2868 +0.6 2.3 conserved hypothetical protein (NCBI ptt file) compare
SO0290 +0.6 1.3 hypothetical protein (NCBI ptt file) compare
SO4686 +0.6 4.9 NAD dependent epimerase/dehydratase family protein (NCBI ptt file) compare
SO4599 +0.6 4.2 ribonuclease, T2 family (NCBI ptt file) compare
SO0548 +0.6 1.8 DNA-binding protein, HU family (NCBI ptt file) compare
SO3271 +0.6 2.7 polysaccharide biosynthesis protein (NCBI ptt file) compare
SO1103 nqrA-2 +0.6 1.5 NADH:ubiquinone oxidoreductase, Na translocating, alpha subunit (NCBI ptt file) compare
SO1328 +0.6 3.2 transcriptional regulator, LysR family (NCBI ptt file) compare
SO4728 +0.6 1.5 conserved hypothetical protein (NCBI ptt file) compare
SO3261 +0.6 3.6 polysaccharide biosynthesis related-protein (NCBI ptt file) compare
SO2268 hscA +0.6 1.3 chaperone protein HscA (NCBI ptt file) compare
SO3936 motX +0.6 3.4 sodium-type flagellar protein MotX (NCBI ptt file) compare
SO4112 mshL +0.6 4.3 MSHA biogenesis protein MshL (NCBI ptt file) compare
SO3677 +0.6 1.8 hypothetical protein (NCBI ptt file) compare
SO2442 thiS +0.6 1.1 thiS protein, putative (NCBI ptt file) compare
SO2232.1 +0.6 1.0 hypothetical ABC transporter (NCBI ptt file) compare
SO3256 +0.6 3.5 conserved hypothetical protein (NCBI ptt file) compare
SO3853 +0.6 1.1 hypothetical protein (NCBI ptt file) compare
SO1112 bfr1 +0.6 2.2 bacterioferritin subunit 1 (NCBI ptt file) compare
SO1560 +0.6 2.6 phosphate-binding protein (NCBI ptt file) compare
SO0568 +0.6 3.0 conserved hypothetical protein (NCBI ptt file) compare


Specific Phenotypes

For 7 genes in this experiment

For carbon source Sodium L-Lactate in Shewanella oneidensis MR-1

For carbon source Sodium L-Lactate across organisms