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Experiment set39S368 for
Burkholderia phytofirmans PsJN
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36hr PHYTO6 MOI 0.1
200 most detrimental genes:
gene
name
fitness
t score
description
BPHYT
_RS11705
+3.5
2.7
hypothetical protein
compare
BPHYT
_RS19570
+3.2
28.0
sodium/hydrogen exchanger
compare
BPHYT
_RS19565
+3.2
22.7
gamma-glutamyl:cysteine ligase
compare
BPHYT
_RS14140
+3.1
5.9
phosphate transporter permease subunit PstC
compare
BPHYT
_RS33820
+2.8
26.3
histidine kinase
compare
BPHYT
_RS02595
+2.5
3.3
sulfurtransferase
compare
BPHYT
_RS27890
+2.5
1.5
hypothetical protein
compare
BPHYT
_RS04335
+2.5
2.3
membrane protein
compare
BPHYT
_RS04945
+2.3
20.6
membrane protein
compare
BPHYT
_RS04950
+2.3
19.9
hypothetical protein
compare
BPHYT
_RS02905
+2.3
20.7
RNA polymerase subunit sigma-54
compare
BPHYT
_RS04965
+2.2
11.5
ATP-binding protein
compare
BPHYT
_RS25935
+2.2
1.8
type III secretion protein
compare
BPHYT
_RS05575
+2.2
19.5
Fis family transcriptional regulator
compare
BPHYT
_RS09330
+2.1
19.4
phytoene synthase
compare
BPHYT
_RS06075
+2.1
8.7
hypothetical protein
compare
BPHYT
_RS09500
+2.0
6.9
glucose-6-phosphate isomerase
compare
BPHYT
_RS05590
+2.0
15.1
trehalose-6-phosphate synthase
compare
BPHYT
_RS14400
+2.0
6.8
anti-sigma factor
compare
BPHYT
_RS02540
+2.0
5.4
hypothetical protein
compare
BPHYT
_RS04940
+1.9
2.9
hypothetical protein
compare
BPHYT
_RS33920
+1.8
13.7
type II citrate synthase
compare
BPHYT
_RS20665
+1.8
1.3
LysR family transcriptional regulator
compare
BPHYT
_RS12845
+1.8
13.8
ATPase
compare
BPHYT
_RS13645
+1.8
15.8
threonine--tRNA ligase
compare
BPHYT
_RS23910
+1.8
7.9
phosphoribosyl-dephospho-CoA transferase
compare
BPHYT
_RS05560
+1.7
7.8
Fis family transcriptional regulator
compare
BPHYT
_RS30750
+1.7
1.9
GntR family transcriptional regulator
compare
BPHYT
_RS04290
+1.7
1.1
glycosyl transferase family 2
compare
BPHYT
_RS12725
+1.7
14.2
regulator
compare
BPHYT
_RS15620
+1.7
4.7
peptidyl-prolyl cis-trans isomerase
compare
BPHYT
_RS05610
+1.7
11.0
DNA-cytosine methyltransferase
compare
BPHYT
_RS06175
+1.7
5.5
LPS biosynthesis
compare
BPHYT
_RS18655
+1.6
6.6
3-oxoacyl-ACP synthase
compare
BPHYT
_RS05155
+1.6
9.9
acetyltransferase GCN5
compare
BPHYT
_RS14485
+1.6
6.4
ribonuclease E
compare
BPHYT
_RS09815
+1.6
2.7
malate synthase
compare
BPHYT
_RS06985
+1.6
6.1
fumarate hydratase
compare
BPHYT
_RS08850
+1.6
0.7
transcriptional regulator
compare
BPHYT
_RS30995
+1.6
0.8
glucose-1-phosphate thymidylyltransferase
compare
BPHYT
_RS09315
+1.6
0.6
chemotaxis protein CheY
compare
BPHYT
_RS14395
+1.6
5.7
sugar dehydratase
compare
BPHYT
_RS20380
+1.5
3.6
LysR family transcriptional regulator
compare
BPHYT
_RS14855
+1.5
0.6
ADP-L-glycero-D-manno-heptose-6-epimerase
compare
BPHYT
_RS06530
+1.5
1.9
membrane protein
compare
BPHYT
_RS07140
+1.5
1.5
hypothetical protein
compare
BPHYT
_RS20155
+1.5
1.1
hypothetical protein
compare
BPHYT
_RS16710
+1.5
0.6
LysR family transcriptional regulator
compare
BPHYT
_RS12290
+1.5
3.3
universal stress protein UspA
compare
BPHYT
_RS09660
+1.4
7.3
trehalose-6-phosphate synthase
compare
BPHYT
_RS28595
+1.4
1.5
glyoxalase
compare
BPHYT
_RS13610
+1.4
2.6
MerR family transcriptional regulator
compare
BPHYT
_RS08945
+1.4
10.4
hypothetical protein
compare
BPHYT
_RS31615
+1.4
1.7
thiamine pyrophosphate protein
compare
BPHYT
_RS18705
+1.4
1.5
5,10-methylenetetrahydrofolate reductase
compare
BPHYT
_RS32495
+1.4
3.2
ABC transporter
compare
BPHYT
_RS16335
+1.4
3.8
membrane protein
compare
BPHYT
_RS26030
+1.4
3.3
cysteine hydrolase
compare
BPHYT
_RS25210
+1.4
1.8
drug:proton antiporter
compare
BPHYT
_RS12150
+1.4
9.9
PII uridylyl-transferase
compare
BPHYT
_RS02865
+1.4
0.8
hypothetical protein
compare
BPHYT
_RS06335
+1.4
1.3
CopG family transcriptional regulator
compare
BPHYT
_RS01630
+1.4
1.5
ATP-dependent protease ATPase subunit HslU
compare
BPHYT
_RS12840
+1.4
3.6
pyruvate dehydrogenase
compare
BPHYT
_RS32830
+1.3
2.4
AraC family transcriptional regulator
compare
BPHYT
_RS14145
+1.3
7.2
phosphate ABC transporter substrate-binding protein
compare
BPHYT
_RS25800
+1.3
0.9
sugar ABC transporter permease
compare
BPHYT
_RS02525
+1.3
6.0
membrane protein
compare
BPHYT
_RS01435
+1.3
10.9
LysR family transcriptional regulator
compare
BPHYT
_RS11815
+1.3
1.5
alcohol dehydrogenase
compare
BPHYT
_RS06455
+1.3
1.4
potassium-transporting ATPase C chain
compare
BPHYT
_RS07760
+1.3
0.9
diguanylate phosphodiesterase
compare
BPHYT
_RS35215
+1.3
1.9
dehydrogenase
compare
BPHYT
_RS32260
+1.3
1.2
hypothetical protein
compare
BPHYT
_RS32395
+1.3
1.1
hypothetical protein
compare
BPHYT
_RS17035
+1.3
1.3
sugar kinase
compare
BPHYT
_RS34185
+1.3
5.2
cold-shock protein
compare
BPHYT
_RS02640
+1.3
9.6
cytochrome C oxidase
compare
BPHYT
_RS24135
+1.3
2.9
alpha-dehydro-beta-deoxy-D-glucarate aldolase
compare
BPHYT
_RS31225
+1.3
2.6
D-alanyl-D-alanine dipeptidase
compare
BPHYT
_RS16675
+1.3
1.4
dihydroorotase
compare
BPHYT
_RS17100
+1.3
4.6
RNA pyrophosphohydrolase
compare
BPHYT
_RS04285
+1.2
0.6
rhamnosyltransferase
compare
BPHYT
_RS11745
+1.2
1.2
(2Fe-2S)-binding protein
compare
BPHYT
_RS29320
+1.2
0.8
histidine kinase
compare
BPHYT
_RS07255
+1.2
1.7
4-oxalocrotonate decarboxylase
compare
BPHYT
_RS23155
+1.2
1.7
Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19)
(from data)
compare
BPHYT
_RS28670
+1.2
1.6
MFS transporter
compare
BPHYT
_RS05615
+1.2
1.0
hypothetical protein
compare
BPHYT
_RS34920
+1.2
1.9
IclR family transcriptional regulator
compare
BPHYT
_RS12985
+1.2
1.2
amino acid acetyltransferase
compare
BPHYT
_RS09355
+1.2
1.5
LysR family transcriptional regulator
compare
BPHYT
_RS03620
+1.2
5.8
poly(A) polymerase
compare
BPHYT
_RS24270
+1.2
1.6
C4-dicarboxylate ABC transporter substrate-binding protein
compare
BPHYT
_RS09850
+1.2
2.2
molybdopterin oxidoreductase
compare
BPHYT
_RS28505
+1.2
1.4
5-deoxyglucuronate isomerase
compare
BPHYT
_RS10320
+1.2
2.6
hypothetical protein
compare
BPHYT
_RS34025
+1.2
1.5
hypothetical protein
compare
BPHYT
_RS07570
+1.2
1.2
hypothetical protein
compare
BPHYT
_RS08995
+1.1
0.9
hypothetical protein
compare
BPHYT
_RS09640
+1.1
5.0
DNAase
compare
BPHYT
_RS01340
+1.1
1.3
ChrB domain-containing protein
compare
BPHYT
_RS07840
+1.1
1.3
muconate cycloisomerase
compare
BPHYT
_RS16175
+1.1
0.7
hemolysin D
compare
BPHYT
_RS02650
+1.1
2.9
membrane protein
compare
BPHYT
_RS03505
+1.1
1.5
FAD-binding protein
compare
BPHYT
_RS06375
+1.1
2.8
ribonuclease
compare
BPHYT
_RS10120
+1.1
2.0
membrane protein
compare
BPHYT
_RS05585
+1.1
4.5
hypothetical protein
compare
BPHYT
_RS07085
+1.1
1.4
LysR family transcriptional regulator
compare
BPHYT
_RS26930
+1.1
5.1
mechanosensitive ion channel protein
compare
BPHYT
_RS02005
+1.1
1.7
diguanylate phosphodiesterase
compare
BPHYT
_RS34445
+1.1
3.0
GntR family transcriptional regulator
compare
BPHYT
_RS27370
+1.1
1.9
CoA transferase
compare
BPHYT
_RS10165
+1.1
0.8
transcriptional regulator
compare
BPHYT
_RS10250
+1.1
2.8
inosine-5-monophosphate dehydrogenase
compare
BPHYT
_RS20750
+1.1
1.4
LacI family transcriptional regulator
compare
BPHYT
_RS02410
+1.1
2.5
alpha/beta hydrolase
compare
BPHYT
_RS10995
+1.1
1.7
GntR family transcriptional regulator
compare
BPHYT
_RS34770
+1.1
1.8
chemotaxis protein
compare
BPHYT
_RS03410
+1.1
1.9
queuine tRNA-ribosyltransferase
compare
BPHYT
_RS13200
+1.1
2.0
molybdopterin binding oxidoreductase
compare
BPHYT
_RS04005
+1.1
2.1
GDP-L-fucose synthase
compare
BPHYT
_RS21025
+1.1
1.3
cation-binding protein
compare
BPHYT
_RS32240
+1.1
1.1
chromosome replication initiation inhibitor protein
compare
BPHYT
_RS09445
+1.1
2.4
trigger factor
compare
BPHYT
_RS13885
+1.1
2.1
myo-inositol 2-dehydrogenase
compare
BPHYT
_RS05670
+1.1
2.0
hypothetical protein
compare
BPHYT
_RS14845
+1.1
0.7
cysteine synthase
compare
BPHYT
_RS00920
+1.1
3.3
transposase
compare
BPHYT
_RS21725
+1.0
1.5
taurine ABC transporter substrate-binding protein
compare
BPHYT
_RS26025
+1.0
0.6
hypothetical protein
compare
BPHYT
_RS16390
+1.0
3.4
MarR family transcriptional regulator
compare
BPHYT
_RS28100
+1.0
2.0
hypothetical protein
compare
BPHYT
_RS26595
+1.0
1.0
carbonic anhydrase
compare
BPHYT
_RS06065
+1.0
5.3
cytochrome C
compare
BPHYT
_RS23210
+1.0
2.3
MFS transporter
compare
BPHYT
_RS12635
+1.0
4.1
translation factor Sua5
compare
BPHYT
_RS17920
+1.0
1.5
protein CyaY
compare
BPHYT
_RS21475
+1.0
1.3
hypothetical protein
compare
BPHYT
_RS20790
+1.0
0.9
TetR family transcriptional regulator
compare
BPHYT
_RS31685
+1.0
2.2
D-isomer specific 2-hydroxyacid dehydrogenase
compare
BPHYT
_RS16210
+1.0
1.8
peptidase
compare
BPHYT
_RS00750
+1.0
3.2
SpoVT/AbrB domain-containing protein
compare
BPHYT
_RS29855
+1.0
1.0
protein-tyrosine-phosphatase
compare
BPHYT
_RS12925
+1.0
0.7
exodeoxyribonuclease III
compare
BPHYT
_RS02635
+1.0
5.9
membrane protein
compare
BPHYT
_RS02530
+1.0
2.9
hypothetical protein
compare
BPHYT
_RS08510
+1.0
1.6
acyl-CoA dehydrogenase
compare
BPHYT
_RS25845
+1.0
0.9
RND transporter MFP subunit
compare
BPHYT
_RS32960
+1.0
2.4
short-chain dehydrogenase
compare
BPHYT
_RS01960
+1.0
2.6
cytochrome C
compare
BPHYT
_RS18255
+1.0
1.5
phenylacetate-CoA oxygenase subunit PaaB
compare
BPHYT
_RS26080
+1.0
0.7
ABC transporter ATPase
compare
BPHYT
_RS05130
+1.0
2.9
hypothetical protein
compare
BPHYT
_RS29720
+1.0
1.1
molybdopterin-guanine dinucleotide biosynthesis protein MobA
compare
BPHYT
_RS21045
+1.0
1.5
bis(5'-nucleosyl)-tetraphosphatase
compare
BPHYT
_RS36470
+1.0
0.6
hypothetical protein
compare
BPHYT
_RS03625
+1.0
4.8
Histidinol-phosphatase (EC:3.1.3.15)
(from data)
compare
BPHYT
_RS21770
+0.9
1.8
aldehyde dehydrogenase
compare
BPHYT
_RS33390
+0.9
1.7
phosphate ABC transporter substrate-binding protein
compare
BPHYT
_RS01240
+0.9
1.8
hypothetical protein
compare
BPHYT
_RS27570
+0.9
2.2
universal stress protein UspA
compare
BPHYT
_RS06070
+0.9
5.7
cytochrome C
compare
BPHYT
_RS15105
+0.9
3.5
FAD-dependent oxidoreductase
compare
BPHYT
_RS23940
+0.9
0.5
GntR family transcriptional regulator
compare
BPHYT
_RS33695
+0.9
1.2
molybdenum ABC transporter ATPase
compare
BPHYT
_RS00340
+0.9
2.3
hypothetical protein
compare
BPHYT
_RS26740
+0.9
1.1
hypothetical protein
compare
BPHYT
_RS27660
+0.9
1.3
hypothetical protein
compare
BPHYT
_RS24510
+0.9
3.1
alkylphosphonate utilization protein
compare
BPHYT
_RS11250
+0.9
2.3
saccharopine dehydrogenase
compare
BPHYT
_RS02210
+0.9
2.6
DeoR family transcriptional regulator
compare
BPHYT
_RS28515
+0.9
2.4
mannonate dehydratase
compare
BPHYT
_RS17640
+0.9
0.6
2-alkenal reductase
compare
BPHYT
_RS28485
+0.9
0.5
GntR family transcriptional regulator
compare
BPHYT
_RS21995
+0.9
1.9
(2Fe-2S)-binding protein
compare
BPHYT
_RS24965
+0.9
1.4
hypothetical protein
compare
BPHYT
_RS18265
+0.9
1.9
phenylacetate-CoA oxygenase subunit PaaJ
compare
BPHYT
_RS34485
+0.9
1.9
diguanylate phosphodiesterase
compare
BPHYT
_RS27845
+0.9
2.2
beta-lactamase
compare
BPHYT
_RS09160
+0.9
4.3
polyhydroxyalkanoate synthesis repressor PhaR
compare
BPHYT
_RS36495
+0.9
2.2
peptidase
compare
BPHYT
_RS17490
+0.9
0.9
haloacid dehalogenase
compare
BPHYT
_RS20010
+0.9
3.9
membrane protein
compare
BPHYT
_RS22855
+0.9
2.9
aldehyde-activating protein
compare
BPHYT
_RS26975
+0.9
1.2
L-lactate dehydrogenase, LldE subunit
(from data)
compare
BPHYT
_RS34495
+0.9
2.0
phenol degradation protein meta
compare
BPHYT
_RS10740
+0.9
0.8
LuxR family transcriptional regulator
compare
BPHYT
_RS23630
+0.9
0.9
hypothetical protein
compare
BPHYT
_RS21585
+0.9
2.7
short-chain dehydrogenase
compare
BPHYT
_RS01965
+0.9
1.2
tRNA-Ala
compare
BPHYT
_RS24975
+0.9
2.0
RNA polymerase sigma24 factor
compare
BPHYT
_RS02985
+0.9
1.1
MaoC family dehydratase
compare
BPHYT
_RS02685
+0.9
5.6
cytochrome C oxidase subunit I
compare
BPHYT
_RS20280
+0.9
2.3
hypothetical protein
compare
BPHYT
_RS09580
+0.9
2.1
2-aminoadipate aminotransferase
compare
BPHYT
_RS24045
+0.9
2.0
amino acid ABC transporter
compare
BPHYT
_RS30645
+0.9
1.3
hypothetical protein
compare
BPHYT
_RS32735
+0.9
3.5
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Burkholderia phytofirmans PsJN in phage experiments