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Experiment set39S358 for
Burkholderia phytofirmans PsJN
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36hr PHYTO10 MOI 10
200 most detrimental genes:
gene
name
fitness
t score
description
BPHYT
_RS09500
+3.1
14.3
glucose-6-phosphate isomerase
compare
BPHYT
_RS14140
+3.1
5.9
phosphate transporter permease subunit PstC
compare
BPHYT
_RS08850
+2.9
1.6
transcriptional regulator
compare
BPHYT
_RS15190
+2.7
5.3
acyl carrier protein
compare
BPHYT
_RS33820
+2.7
25.5
histidine kinase
compare
BPHYT
_RS11705
+2.6
2.8
hypothetical protein
compare
BPHYT
_RS06175
+2.5
10.3
LPS biosynthesis
compare
BPHYT
_RS04285
+2.5
1.4
rhamnosyltransferase
compare
BPHYT
_RS05575
+2.4
21.2
Fis family transcriptional regulator
compare
BPHYT
_RS01455
+2.3
3.1
peptide deformylase
compare
BPHYT
_RS14400
+2.3
7.0
anti-sigma factor
compare
BPHYT
_RS01435
+2.2
19.4
LysR family transcriptional regulator
compare
BPHYT
_RS05560
+2.2
11.5
Fis family transcriptional regulator
compare
BPHYT
_RS16710
+2.2
1.0
LysR family transcriptional regulator
compare
BPHYT
_RS02595
+2.1
3.2
sulfurtransferase
compare
BPHYT
_RS10065
+2.1
2.3
cytochrome C oxidase subunit I
compare
BPHYT
_RS18655
+2.1
9.4
3-oxoacyl-ACP synthase
compare
BPHYT
_RS03725
+2.1
1.5
serine hydroxymethyltransferase
compare
BPHYT
_RS14855
+2.0
0.8
ADP-L-glycero-D-manno-heptose-6-epimerase
compare
BPHYT
_RS02865
+2.0
1.5
hypothetical protein
compare
BPHYT
_RS09330
+2.0
18.5
phytoene synthase
compare
BPHYT
_RS07255
+2.0
3.6
4-oxalocrotonate decarboxylase
compare
BPHYT
_RS05590
+2.0
14.7
trehalose-6-phosphate synthase
compare
BPHYT
_RS04950
+2.0
14.2
hypothetical protein
compare
BPHYT
_RS12845
+1.9
16.1
ATPase
compare
BPHYT
_RS04945
+1.9
17.0
membrane protein
compare
BPHYT
_RS16840
+1.9
4.4
transketolase
compare
BPHYT
_RS06985
+1.9
12.2
fumarate hydratase
compare
BPHYT
_RS14395
+1.9
8.9
sugar dehydratase
compare
BPHYT
_RS04290
+1.8
0.9
glycosyl transferase family 2
compare
BPHYT
_RS15145
+1.8
4.6
3-oxoacyl-ACP synthase
compare
BPHYT
_RS22835
+1.8
1.6
flagellar motor protein MotA
compare
BPHYT
_RS26685
+1.8
1.7
precorrin-8X methylmutase
compare
BPHYT
_RS25935
+1.7
1.7
type III secretion protein
compare
BPHYT
_RS33920
+1.7
12.2
type II citrate synthase
compare
BPHYT
_RS31225
+1.7
4.2
D-alanyl-D-alanine dipeptidase
compare
BPHYT
_RS18600
+1.7
3.1
glutathione S-transferase
compare
BPHYT
_RS12725
+1.7
14.1
regulator
compare
BPHYT
_RS16175
+1.6
1.0
hemolysin D
compare
BPHYT
_RS06075
+1.6
7.5
hypothetical protein
compare
BPHYT
_RS03455
+1.6
4.0
paraquat-inducible protein A
compare
BPHYT
_RS26390
+1.6
1.5
antibiotic resistance protein
compare
BPHYT
_RS27890
+1.6
0.8
hypothetical protein
compare
BPHYT
_RS14145
+1.6
7.8
phosphate ABC transporter substrate-binding protein
compare
BPHYT
_RS05155
+1.5
10.6
acetyltransferase GCN5
compare
BPHYT
_RS32260
+1.5
1.4
hypothetical protein
compare
BPHYT
_RS23910
+1.5
4.4
phosphoribosyl-dephospho-CoA transferase
compare
BPHYT
_RS09660
+1.5
8.0
trehalose-6-phosphate synthase
compare
BPHYT
_RS35310
+1.5
2.1
GCN5 family N-acetyltransferase
compare
BPHYT
_RS14845
+1.5
0.9
cysteine synthase
compare
BPHYT
_RS12150
+1.5
10.8
PII uridylyl-transferase
compare
BPHYT
_RS34655
+1.5
1.3
2-amino-3-ketobutyrate CoA ligase
compare
BPHYT
_RS27370
+1.5
2.2
CoA transferase
compare
BPHYT
_RS17290
+1.5
10.1
porin
compare
BPHYT
_RS30990
+1.5
2.5
dTDP-4-dehydrorhamnose 3,5-epimerase
compare
BPHYT
_RS19565
+1.5
9.1
gamma-glutamyl:cysteine ligase
compare
BPHYT
_RS17035
+1.4
0.9
sugar kinase
compare
BPHYT
_RS12990
+1.4
3.7
iron transporter
compare
BPHYT
_RS17640
+1.4
0.9
2-alkenal reductase
compare
BPHYT
_RS04385
+1.4
3.0
nucleoside-diphosphate sugar oxidoreductase
compare
BPHYT
_RS15195
+1.4
9.0
glycerol acyltransferase
compare
BPHYT
_RS21025
+1.4
1.7
cation-binding protein
compare
BPHYT
_RS16335
+1.4
3.8
membrane protein
compare
BPHYT
_RS04315
+1.4
5.5
UDP-N-acetylglucosamine 2-epimerase
compare
BPHYT
_RS28025
+1.4
1.5
3-hydroxyisobutyrate dehydrogenase
compare
BPHYT
_RS02905
+1.4
12.3
RNA polymerase subunit sigma-54
compare
BPHYT
_RS22860
+1.4
1.7
chemotaxis protein CheY
compare
BPHYT
_RS02540
+1.4
3.2
hypothetical protein
compare
BPHYT
_RS17165
+1.4
1.8
cell division protein ZapD
compare
BPHYT
_RS02880
+1.4
2.1
ATP-dependent protease
compare
BPHYT
_RS30810
+1.4
2.3
transcriptional regulator
compare
BPHYT
_RS15620
+1.4
4.6
peptidyl-prolyl cis-trans isomerase
compare
BPHYT
_RS08945
+1.4
5.4
hypothetical protein
compare
BPHYT
_RS25770
+1.4
1.2
hypothetical protein
compare
BPHYT
_RS25340
+1.3
2.6
sulfatase
compare
BPHYT
_RS04940
+1.3
2.1
hypothetical protein
compare
BPHYT
_RS02860
+1.3
0.7
membrane protein
compare
BPHYT
_RS16065
+1.3
0.9
LacI family transcriptional regulator
compare
BPHYT
_RS15175
+1.3
6.9
AMP-dependent synthetase
compare
BPHYT
_RS19570
+1.3
9.4
sodium/hydrogen exchanger
compare
BPHYT
_RS13200
+1.3
2.4
molybdopterin binding oxidoreductase
compare
BPHYT
_RS09815
+1.3
3.4
malate synthase
compare
BPHYT
_RS33515
+1.3
6.9
porin
compare
BPHYT
_RS32860
+1.3
1.1
hypothetical protein
compare
BPHYT
_RS26025
+1.3
0.7
hypothetical protein
compare
BPHYT
_RS06375
+1.3
2.7
ribonuclease
compare
BPHYT
_RS02760
+1.3
0.8
cytochrome BD oxidase subunit II
compare
BPHYT
_RS28065
+1.3
1.6
hypothetical protein
compare
BPHYT
_RS11040
+1.2
2.2
GntR family transcriptional regulator
compare
BPHYT
_RS06195
+1.2
1.5
membrane protein
compare
BPHYT
_RS20280
+1.2
1.9
hypothetical protein
compare
BPHYT
_RS10710
+1.2
1.4
sensor histidine kinase
compare
BPHYT
_RS09825
+1.2
2.0
Fe-S protein
compare
BPHYT
_RS22060
+1.2
10.3
amino acid transporter
compare
BPHYT
_RS16210
+1.2
2.6
peptidase
compare
BPHYT
_RS10215
+1.2
1.0
sulfate transporter
compare
BPHYT
_RS26040
+1.2
2.4
cysteine hydrolase
compare
BPHYT
_RS02650
+1.2
3.0
membrane protein
compare
BPHYT
_RS15200
+1.2
4.3
hypothetical protein
compare
BPHYT
_RS21910
+1.2
1.6
ABC transporter permease
compare
BPHYT
_RS04095
+1.2
0.9
SAM-dependent methyltransferase PhcB
compare
BPHYT
_RS23540
+1.2
3.1
RND transporter
compare
BPHYT
_RS16345
+1.2
3.3
succinyl-CoA ligase [ADP-forming] subunit beta
compare
BPHYT
_RS21990
+1.1
3.0
FAD-dependent oxidoreductase
compare
BPHYT
_RS03460
+1.1
5.8
mammalian cell entry protein
compare
BPHYT
_RS29410
+1.1
4.3
HPr kinase
compare
BPHYT
_RS35770
+1.1
1.0
glyoxalase
compare
BPHYT
_RS11010
+1.1
2.1
chromate transporter
compare
BPHYT
_RS10740
+1.1
1.0
LuxR family transcriptional regulator
compare
BPHYT
_RS02530
+1.1
5.6
hypothetical protein
compare
BPHYT
_RS15170
+1.1
5.4
family 2 glycosyl transferase
compare
BPHYT
_RS23975
+1.1
1.4
peroxidase
compare
BPHYT
_RS35480
+1.1
2.2
salicylyl-CoA 5-hydroxylase
compare
BPHYT
_RS23270
+1.1
1.1
enoyl-CoA hydratase
compare
BPHYT
_RS36400
+1.1
1.4
hypothetical protein
compare
BPHYT
_RS20150
+1.1
1.6
glycosyl transferase family 1
compare
BPHYT
_RS23155
+1.1
1.4
Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19)
(from data)
compare
BPHYT
_RS32200
+1.1
1.8
lytic transglycosylase
compare
BPHYT
_RS05190
+1.1
4.4
ADP-heptose--LPS heptosyltransferase
compare
BPHYT
_RS05905
+1.1
1.0
hypothetical protein
compare
BPHYT
_RS09850
+1.1
1.9
molybdopterin oxidoreductase
compare
BPHYT
_RS09145
+1.1
6.8
poly-beta-hydroxybutyrate polymerase
compare
BPHYT
_RS32110
+1.1
1.6
transcriptional regulator
compare
BPHYT
_RS05585
+1.1
4.1
hypothetical protein
compare
BPHYT
_RS31615
+1.1
1.6
thiamine pyrophosphate protein
compare
BPHYT
_RS30860
+1.1
2.3
sugar ABC transporter permease
compare
BPHYT
_RS24135
+1.0
1.7
alpha-dehydro-beta-deoxy-D-glucarate aldolase
compare
BPHYT
_RS04335
+1.0
0.7
membrane protein
compare
BPHYT
_RS15140
+1.0
4.3
beta-hydroxyacyl-ACP dehydratase
compare
BPHYT
_RS05670
+1.0
2.8
hypothetical protein
compare
BPHYT
_RS20155
+1.0
0.9
hypothetical protein
compare
BPHYT
_RS03450
+1.0
4.5
paraquat-inducible protein A
compare
BPHYT
_RS31205
+1.0
1.2
peptide ABC transporter ATP-binding protein
compare
BPHYT
_RS16340
+1.0
4.4
succinyl-CoA synthetase subunit alpha
compare
BPHYT
_RS08510
+1.0
1.7
acyl-CoA dehydrogenase
compare
BPHYT
_RS04300
+1.0
5.4
family 2 glycosyl transferase
compare
BPHYT
_RS26780
+1.0
4.6
chemotaxis protein CheR
compare
BPHYT
_RS16290
+1.0
1.5
hypothetical protein
compare
BPHYT
_RS36000
+1.0
1.7
hypothetical protein
compare
BPHYT
_RS26030
+1.0
2.3
cysteine hydrolase
compare
BPHYT
_RS16180
+1.0
0.5
TetR family transcriptional regulator
compare
BPHYT
_RS21805
+1.0
1.6
transcriptional regulator
compare
BPHYT
_RS12985
+1.0
0.9
amino acid acetyltransferase
compare
BPHYT
_RS26080
+1.0
0.7
ABC transporter ATPase
compare
BPHYT
_RS07450
+1.0
1.4
histidine kinase
compare
BPHYT
_RS15155
+1.0
5.2
hypothetical protein
compare
BPHYT
_RS15160
+1.0
4.3
hypothetical protein
compare
BPHYT
_RS11125
+1.0
1.0
alkylhydroperoxidase
compare
BPHYT
_RS33400
+1.0
2.3
magnesium transporter CorA
compare
BPHYT
_RS28985
+1.0
3.3
hypothetical protein
compare
BPHYT
_RS06350
+1.0
1.2
chemotaxis protein CheY
compare
BPHYT
_RS15130
+1.0
5.4
3-oxoacyl-ACP synthase
compare
BPHYT
_RS10145
+1.0
3.6
Mn-containing catalase
compare
BPHYT
_RS17490
+1.0
1.3
haloacid dehalogenase
compare
BPHYT
_RS24495
+1.0
2.1
transcriptional regulator
compare
BPHYT
_RS06610
+1.0
1.1
triosephosphate isomerase
compare
BPHYT
_RS26930
+1.0
4.3
mechanosensitive ion channel protein
compare
BPHYT
_RS15165
+1.0
3.9
histidine ammonia-lyase
compare
BPHYT
_RS11495
+1.0
1.9
membrane protein
compare
BPHYT
_RS20055
+1.0
1.1
hypothetical protein
compare
BPHYT
_RS30465
+1.0
1.1
short-chain dehydrogenase
compare
BPHYT
_RS16245
+1.0
3.0
phosphoribosylaminoimidazole carboxylase
compare
BPHYT
_RS27295
+1.0
1.6
hypothetical protein
compare
BPHYT
_RS14340
+1.0
5.8
Fis family transcriptional regulator
compare
BPHYT
_RS24270
+1.0
1.5
C4-dicarboxylate ABC transporter substrate-binding protein
compare
BPHYT
_RS19125
+1.0
2.3
short-chain dehydrogenase
compare
BPHYT
_RS04015
+1.0
1.9
glycosyl transferase
compare
BPHYT
_RS23955
+1.0
2.5
LysR family transcriptional regulator
compare
BPHYT
_RS09620
+0.9
1.0
aminodeoxychorismate lyase
compare
BPHYT
_RS24665
+0.9
1.5
ABC transporter permease
compare
BPHYT
_RS30425
+0.9
1.5
LysR family transcriptional regulator
compare
BPHYT
_RS30865
+0.9
2.5
sugar ABC transporter ATP-binding protein
compare
BPHYT
_RS33695
+0.9
1.2
molybdenum ABC transporter ATPase
compare
BPHYT
_RS18255
+0.9
1.3
phenylacetate-CoA oxygenase subunit PaaB
compare
BPHYT
_RS24770
+0.9
1.6
DeoR family transcriptional regulator
compare
BPHYT
_RS05615
+0.9
1.2
hypothetical protein
compare
BPHYT
_RS17705
+0.9
5.8
histidinol-phosphate aminotransferase
compare
BPHYT
_RS08125
+0.9
5.8
ATPase
compare
BPHYT
_RS02525
+0.9
5.1
membrane protein
compare
BPHYT
_RS20545
+0.9
0.8
hypothetical protein
compare
BPHYT
_RS23230
+0.9
2.0
histidine kinase
compare
BPHYT
_RS11170
+0.9
0.6
hypothetical protein
compare
BPHYT
_RS02640
+0.9
6.9
cytochrome C oxidase
compare
BPHYT
_RS06190
+0.9
0.7
heptosyltransferase
compare
BPHYT
_RS21445
+0.9
1.2
sugar ABC transporter ATP-binding protein
compare
BPHYT
_RS26570
+0.9
0.8
5'-nucleotidase
compare
BPHYT
_RS17750
+0.9
6.6
VacJ family lipoprotein
compare
BPHYT
_RS15150
+0.9
4.9
membrane protein
compare
BPHYT
_RS08960
+0.9
0.4
threonine synthase
compare
BPHYT
_RS12500
+0.9
1.4
hypothetical protein
compare
BPHYT
_RS02435
+0.9
1.3
hypothetical protein
compare
BPHYT
_RS21575
+0.9
2.3
hypothetical protein
compare
BPHYT
_RS24405
+0.9
2.9
type VI secretion system effector
compare
BPHYT
_RS14130
+0.9
3.2
phosphate ABC transporter ATP-binding protein
compare
BPHYT
_RS28505
+0.9
1.1
5-deoxyglucuronate isomerase
compare
BPHYT
_RS29325
+0.9
3.7
histidine kinase
compare
BPHYT
_RS20070
+0.9
0.9
hypothetical protein
compare
BPHYT
_RS18635
+0.9
1.8
LamB/YcsF family protein
compare
BPHYT
_RS25410
+0.9
1.5
porin
compare
BPHYT
_RS09280
+0.9
0.6
pyridoxal-5'-phosphate-dependent protein subunit beta
compare
Specific Phenotypes
For 5 genes in this experiment