Experiment set36S465 for Bacteroides thetaiotaomicron VPI-5482

Stool_Day7_Mouse9

Group: mouse; methotrexate
Media: + Methotrexate (5 mg/kg)
Culturing: Btheta_ML6a
By: Nayak-UCSF-RBAD on 10/31/24

Specific Phenotypes

For 11 genes in this experiment

For mouse; methotrexate Methotrexate in Bacteroides thetaiotaomicron VPI-5482

For mouse; methotrexate Methotrexate across organisms

SEED Subsystems

Subsystem	#Specific
Multidrug Resistance Efflux Pumps	3
Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)	3
Cysteine Biosynthesis	1
Galactosylceramide and Sulfatide metabolism	1
Lactose and Galactose Uptake and Utilization	1
Lactose utilization	1
Respiratory Complex I	1

Metabolic Maps

Color code by fitness: see overview map or list of maps.

Maps containing gene(s) with specific phenotypes:

• Galactose metabolism
• Oxidative phosphorylation
• Other glycan degradation
• Glycosaminoglycan degradation
• Sphingolipid metabolism
• Glycosphingolipid biosynthesis - ganglio series

MetaCyc Pathways

Pathways that contain genes with specific phenotypes:

Pathway	#Steps	#Present	#Specific
lactose degradation III	1	1	1
NADH to cytochrome bd oxidase electron transfer I	2	1	1
NADH to cytochrome bo oxidase electron transfer I	2	1	1
xyloglucan degradation II (exoglucanase)	8	5	3
aerobic respiration III (alternative oxidase pathway)	3	2	1
aerobic respiration I (cytochrome c)	4	2	1
NAD(P)/NADPH interconversion	6	2	1
Fe(II) oxidation	6	1	1