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Experiment set36IT059 for
Klebsiella michiganensis M5al
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KLEB28 MOI 0.1
200 most detrimental genes:
gene
name
fitness
t score
description
BWI76
_RS25285
+1.2
2.0
HPr family phosphocarrier protein
compare
BWI76
_RS00400
+1.0
1.1
glutamine synthetase
compare
BWI76
_RS11015
+1.0
1.7
hypothetical protein
compare
BWI76
_RS05570
+0.9
2.0
hypothetical protein
compare
BWI76
_RS07465
+0.9
1.4
TetR family transcriptional regulator
compare
BWI76
_RS15670
+0.9
2.4
hypothetical protein
compare
BWI76
_RS09860
+0.8
3.6
hypothetical protein
compare
BWI76
_RS07985
+0.8
1.4
fluoride ion transporter CrcB
compare
BWI76
_RS08765
+0.8
2.5
8-amino-7-oxononanoate synthase
compare
BWI76
_RS13445
+0.8
0.9
alpha/beta hydrolase
compare
BWI76
_RS21685
+0.8
1.7
hypothetical protein
compare
BWI76
_RS11700
+0.8
1.4
hypothetical protein
compare
BWI76
_RS11435
+0.8
1.7
hypothetical protein
compare
BWI76
_RS24955
+0.8
2.8
hypothetical protein
compare
BWI76
_RS27875
+0.8
1.9
membrane protein
compare
BWI76
_RS08330
+0.8
1.9
hypothetical protein
compare
BWI76
_RS14975
+0.8
2.3
glyoxalase-like domain protein
compare
BWI76
_RS24575
+0.8
1.9
hypothetical protein
compare
BWI76
_RS21980
+0.8
2.2
hypothetical protein
compare
BWI76
_RS11980
+0.7
1.8
DeoR family transcriptional regulator
compare
BWI76
_RS18580
+0.7
1.9
hypothetical protein
compare
BWI76
_RS17330
+0.7
2.2
nitrate reductase subunit beta
compare
BWI76
_RS09560
+0.7
1.8
DoxX family membrane protein
compare
BWI76
_RS12465
+0.7
1.3
phage shock protein D
compare
BWI76
_RS15205
+0.7
3.1
succinate-semialdehyde dehydrogenase
compare
BWI76
_RS19650
+0.7
2.2
DNA-binding transcriptional regulator GalS
compare
BWI76
_RS14390
+0.7
1.9
hypothetical protein
compare
BWI76
_RS21460
+0.7
1.4
translation inhibitor protein RaiA
compare
BWI76
_RS02580
+0.7
0.9
23S rRNA (guanosine(2251)-2'-O)-methyltransferase
compare
BWI76
_RS23030
+0.7
1.8
cobalamin biosynthesis protein CbiM
compare
BWI76
_RS22130
+0.7
2.0
fructose-1-phosphate/6-phosphogluconate phosphatase
compare
BWI76
_RS11235
+0.7
1.0
hypothetical protein
compare
BWI76
_RS19330
+0.7
1.1
HAD family hydrolase
compare
BWI76
_RS25375
+0.7
2.8
hypothetical protein
compare
BWI76
_RS13590
+0.7
1.6
hypothetical protein
compare
BWI76
_RS20155
+0.6
2.1
NADH-quinone oxidoreductase subunit I
compare
BWI76
_RS15920
+0.6
1.3
hypothetical protein
compare
BWI76
_RS14075
+0.6
0.9
TetR family transcriptional regulator
compare
BWI76
_RS22350
+0.6
2.5
hydrogenase nickel incorporation protein HypB
compare
BWI76
_RS12870
+0.6
0.7
putative phytanoyl-CoA dioxygenase
compare
BWI76
_RS21285
+0.6
1.5
HAD family hydrolase
compare
BWI76
_RS17765
+0.6
2.2
hypothetical protein
compare
BWI76
_RS19935
+0.6
1.3
hypothetical protein
compare
BWI76
_RS15350
+0.6
1.2
hypothetical protein
compare
BWI76
_RS10955
+0.6
1.7
hypothetical protein
compare
BWI76
_RS24925
+0.6
1.2
DnaA initiator-associating protein DiaA
compare
BWI76
_RS15260
+0.6
1.4
hypothetical protein
compare
BWI76
_RS12040
+0.6
1.1
hypothetical protein
compare
BWI76
_RS12485
+0.6
2.1
TyrR family transcriptional regulator
compare
BWI76
_RS00795
+0.6
1.8
carboxymuconolactone decarboxylase
compare
BWI76
_RS06475
+0.6
1.0
protoheme IX farnesyltransferase
compare
BWI76
_RS11520
+0.6
1.1
hypothetical protein
compare
BWI76
_RS26045
+0.6
1.4
nitrite reductase small subunit
compare
BWI76
_RS20880
+0.6
1.9
esterase
compare
BWI76
_RS13480
+0.6
1.5
XRE family transcriptional regulator
compare
BWI76
_RS17390
+0.6
2.1
DsrE family protein
compare
BWI76
_RS12860
+0.6
1.0
hypothetical protein
compare
BWI76
_RS18430
+0.6
2.1
hypothetical protein
compare
BWI76
_RS01540
+0.6
1.8
thiamine biosynthesis protein ThiS
compare
BWI76
_RS13730
+0.6
2.0
hypothetical protein
compare
BWI76
_RS17770
+0.6
1.7
isomerase/hydrolase
compare
BWI76
_RS10910
+0.6
2.2
hypothetical protein
compare
BWI76
_RS17300
+0.6
0.9
tRNA-Tyr
compare
BWI76
_RS18595
+0.6
3.3
hypothetical protein
compare
BWI76
_RS11200
+0.6
1.2
transpeptidase
compare
BWI76
_RS02855
+0.6
1.4
cytochrome B562
compare
BWI76
_RS17375
+0.5
1.3
nitrate ABC transporter, permease protein
compare
BWI76
_RS13610
+0.5
1.9
sugar transporter
compare
BWI76
_RS18165
+0.5
0.6
NUDIX pyrophosphatase
compare
BWI76
_RS20230
+0.5
1.5
hypothetical protein
compare
BWI76
_RS16445
+0.5
2.3
auxiliary transporter membrane fusion protein
compare
BWI76
_RS23155
+0.5
2.6
microcompartment protein PduM
compare
BWI76
_RS19325
+0.5
1.4
mandelate racemase
compare
BWI76
_RS09825
+0.5
2.2
envelope biogenesis factor ElyC
compare
BWI76
_RS09285
+0.5
1.4
hypothetical protein
compare
BWI76
_RS13820
+0.5
0.7
hypothetical protein
compare
BWI76
_RS12330
+0.5
2.4
hypothetical protein
compare
BWI76
_RS12605
+0.5
1.7
hypothetical protein
compare
BWI76
_RS06080
+0.5
2.3
taurine dioxygenase
compare
BWI76
_RS00640
+0.5
1.1
L-rhamnose mutarotase
compare
BWI76
_RS25220
+0.5
2.0
outer membrane lipid asymmetry maintenance protein MlaD
compare
BWI76
_RS25960
+0.5
1.8
NUDIX hydrolase
compare
BWI76
_RS07475
+0.5
0.9
DNA-binding transcriptional regulator RamA
compare
BWI76
_RS06815
+0.5
1.5
adenine phosphoribosyltransferase
compare
BWI76
_RS20380
+0.5
0.7
tRNA pseudouridine(38-40) synthase TruA
compare
BWI76
_RS16675
+0.5
1.1
ABC transporter
compare
BWI76
_RS17280
+0.5
2.6
patatin family protein
compare
BWI76
_RS27835
+0.5
1.3
acyltransferase
compare
BWI76
_RS17235
+0.5
2.0
peptide ABC transporter permease
compare
BWI76
_RS08040
+0.5
1.6
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
compare
BWI76
_RS16080
+0.5
1.2
LysR family transcriptional regulator
compare
BWI76
_RS14575
+0.5
2.1
TENA/THI-4 family protein
compare
BWI76
_RS27425
+0.5
1.7
DNA-directed RNA polymerase subunit omega
compare
BWI76
_RS17210
+0.5
2.1
dsDNA-mimic protein
compare
BWI76
_RS06400
+0.5
1.7
oxidative-stress-resistance chaperone
compare
BWI76
_RS19840
+0.5
0.6
hypothetical protein
compare
BWI76
_RS05540
+0.5
2.6
cytosol nonspecific dipeptidase
compare
BWI76
_RS25205
+0.5
1.4
hypothetical protein
compare
BWI76
_RS19750
+0.5
1.3
elongation factor P-like protein YeiP
compare
BWI76
_RS13160
+0.5
1.3
azoreductase
compare
BWI76
_RS19880
+0.5
2.7
magnesium transporter
compare
BWI76
_RS14015
+0.5
1.6
L-2,4-diaminobutyrate decarboxylase
compare
BWI76
_RS25925
+0.5
2.0
hypothetical protein
compare
BWI76
_RS03315
+0.5
2.2
clavaldehyde dehydrogenase
compare
BWI76
_RS17180
+0.5
1.4
hypothetical protein
compare
BWI76
_RS22530
+0.5
2.2
macrolide ABC transporter permease/ATP-binding protein MacB
compare
BWI76
_RS27605
+0.5
1.2
hypothetical protein
compare
BWI76
_RS18695
+0.5
2.3
GntR family transcriptional regulator
compare
BWI76
_RS25680
+0.5
1.3
16S rRNA m5C967 methyltransferase
compare
BWI76
_RS13965
+0.5
1.7
binding-protein-dependent transport system inner membrane protein
compare
BWI76
_RS01690
+0.5
2.4
membrane protein
compare
BWI76
_RS21075
+0.5
0.7
membrane protein
compare
BWI76
_RS18075
+0.5
2.2
oligopeptidase B
compare
BWI76
_RS14040
+0.4
2.0
thiaminase
compare
BWI76
_RS09535
+0.4
1.5
N-acetylmuramoyl-L-alanine amidase amid
compare
BWI76
_RS03180
+0.4
2.2
phage transcriptional regulator, AlpA
compare
BWI76
_RS25225
+0.4
1.8
ABC transporter permease
compare
BWI76
_RS14715
+0.4
1.3
type I methionyl aminopeptidase
compare
BWI76
_RS16035
+0.4
1.6
biotin-independent malonate decarboxylase subunit beta
compare
BWI76
_RS02255
+0.4
1.8
chaperone-modulator protein CbpM
compare
BWI76
_RS19315
+0.4
2.6
ABC transporter permease
compare
BWI76
_RS08350
+0.4
1.6
carboxylase
compare
BWI76
_RS14285
+0.4
2.2
IS3 family transposase
compare
BWI76
_RS15360
+0.4
1.0
hypothetical protein
compare
BWI76
_RS12480
+0.4
1.5
TIGR01620 family protein
compare
BWI76
_RS16795
+0.4
1.1
amino acid ABC transporter ATPase
compare
BWI76
_RS17110
+0.4
1.0
vitamin B12 ABC transporter permease BtuC
compare
BWI76
_RS09340
+0.4
2.4
baseplate assembly protein J
compare
BWI76
_RS18770
+0.4
0.7
DNA gyrase inhibitor
compare
BWI76
_RS23125
+0.4
1.4
propanediol dehydratase small subunit
compare
BWI76
_RS01235
+0.4
1.4
hypothetical protein
compare
BWI76
_RS21365
+0.4
2.2
tRNA (adenosine(37)-N6)-methyltransferase TrmM
compare
BWI76
_RS05950
+0.4
1.2
polar amino acid ABC transporter inner membrane subunit
compare
BWI76
_RS10510
+0.4
1.4
OHCU decarboxylase
compare
BWI76
_RS01675
+0.4
1.5
putative cytoplasmic protein
compare
BWI76
_RS10815
+0.4
1.9
iron permease
compare
BWI76
_RS24270
+0.4
0.8
membrane protein
compare
BWI76
_RS09470
+0.4
1.2
putrescine ABC transporter permease
compare
BWI76
_RS25400
+0.4
2.9
L(+)-tartrate dehydratase subunit alpha
compare
BWI76
_RS01520
+0.4
2.3
PTS sugar transporter subunit IIB
compare
BWI76
_RS05810
+0.4
0.8
hypothetical protein
compare
BWI76
_RS15755
+0.4
1.8
hypothetical protein
compare
BWI76
_RS12815
+0.4
1.9
transcriptional regulator FeaR
compare
BWI76
_RS11445
+0.4
2.2
hypothetical protein
compare
BWI76
_RS01620
+0.4
1.6
hypothetical protein
compare
BWI76
_RS14065
+0.4
1.1
hypothetical protein
compare
BWI76
_RS05335
+0.4
1.8
copper homeostasis/adhesion lipoprotein NlpE
compare
BWI76
_RS15940
+0.4
1.5
DMSO reductase maturation protein DsmD
compare
BWI76
_RS23970
+0.4
1.8
mechanosensitive ion channel protein MscS
compare
BWI76
_RS01605
+0.4
2.9
transcriptional regulatory protein ZraR
compare
BWI76
_RS10445
+0.4
2.3
hypothetical protein
compare
BWI76
_RS16095
+0.4
1.5
thiamine biosynthesis protein ApbE
compare
BWI76
_RS25580
+0.4
3.1
MexX family efflux pump subunit
compare
BWI76
_RS06735
+0.4
1.3
50S ribosomal protein L31
compare
BWI76
_RS17185
+0.4
2.0
fructosamine kinase family protein
compare
BWI76
_RS16075
+0.4
0.8
oxidoreductase
compare
BWI76
_RS00785
+0.4
1.7
cystathionine gamma-synthase
compare
BWI76
_RS09720
+0.4
2.0
PTS ascorbate transporter subunit IIB
compare
BWI76
_RS06910
+0.4
0.9
transcriptional regulator
compare
BWI76
_RS16340
+0.4
2.2
aryl-phospho-beta-D-glucosidase
compare
BWI76
_RS16805
+0.4
1.0
basic amino acid ABC transporter substrate-binding protein
compare
BWI76
_RS09765
+0.4
1.6
metalloprotease
compare
BWI76
_RS07325
+0.4
1.8
aminoimidazole riboside kinase
compare
BWI76
_RS26235
+0.4
1.6
gluconate transporter
compare
BWI76
_RS25945
+0.4
1.4
ABC transporter ATP-binding protein
compare
BWI76
_RS11950
+0.4
1.5
phosphatidylglycerophosphatase B
compare
BWI76
_RS22940
+0.4
2.1
DNA-binding transcriptional activator FucR
compare
BWI76
_RS01360
+0.4
2.5
acetyl-CoA C-acyltransferase FadA
compare
BWI76
_RS08705
+0.4
1.4
putative LuxR family regulatory protein
compare
BWI76
_RS15050
+0.4
1.4
sugar transporter
compare
BWI76
_RS20930
+0.4
0.8
arsenate reductase (glutaredoxin)
compare
BWI76
_RS01580
+0.4
1.4
hypothetical protein
compare
BWI76
_RS25635
+0.4
1.6
gamma carbonic anhydrase family protein
compare
BWI76
_RS10965
+0.4
2.0
sulfurtransferase
compare
BWI76
_RS18060
+0.4
1.7
hypothetical protein
compare
BWI76
_RS18620
+0.4
1.7
L,D-transpeptidase
compare
BWI76
_RS17310
+0.4
1.1
AsnC family transcriptional regulator
compare
BWI76
_RS22475
+0.4
1.0
heme ABC transporter ATP-binding protein
compare
BWI76
_RS07255
+0.4
1.0
hypothetical protein
compare
BWI76
_RS18495
+0.4
2.6
hypothetical protein
compare
BWI76
_RS13770
+0.4
1.2
alkylhydroperoxidase domain protein
compare
BWI76
_RS09895
+0.4
1.1
aliphatic sulfonates ABC transporter ATP-binding protein
compare
BWI76
_RS18065
+0.4
1.0
DNA polymerase III subunit theta
compare
BWI76
_RS10685
+0.4
2.6
LysR family transcriptional regulator
compare
BWI76
_RS02920
+0.4
1.5
addiction module toxin RelE
compare
BWI76
_RS12080
+0.4
1.9
hypothetical protein
compare
BWI76
_RS26890
+0.4
0.7
hypothetical protein
compare
BWI76
_RS18385
+0.4
0.7
hypothetical protein
compare
BWI76
_RS04770
+0.4
1.6
D-alanine--D-alanine ligase
compare
BWI76
_RS12270
+0.4
1.5
hypothetical protein
compare
BWI76
_RS02050
+0.4
1.3
CidA/LrgA family protein
compare
BWI76
_RS22095
+0.4
1.4
multidrug export protein EmrA
compare
BWI76
_RS08785
+0.4
1.6
excinuclease ABC subunit B
compare
BWI76
_RS17290
+0.4
1.7
formyltetrahydrofolate deformylase
compare
BWI76
_RS03435
+0.4
2.1
mandelate racemase/muconate lactonizing protein
compare
BWI76
_RS12735
+0.4
1.3
phage repressor protein
compare
BWI76
_RS19835
+0.4
1.4
nucleoid-associated protein YejK
compare
BWI76
_RS20730
+0.4
0.8
hypothetical protein
compare
BWI76
_RS25485
+0.4
0.8
septum formation protein Maf
compare
BWI76
_RS13215
+0.4
0.7
type I glyceraldehyde-3-phosphate dehydrogenase
compare
Specific Phenotypes
None in this experiment
For Klebsiella michiganensis M5al in phage experiments