Experiment set36IT044 for Klebsiella michiganensis M5al

Compare to:

KLEB15 MOI 1

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS27310 +3.7 26.7 glycosyltransferase compare
BWI76_RS15825 +2.1 1.5 hypothetical protein compare
BWI76_RS09970 +1.8 3.6 porin OmpA compare
BWI76_RS01195 +1.3 3.3 membrane protein compare
BWI76_RS03080 +1.1 3.9 (Fe-S)-cluster assembly protein compare
BWI76_RS19840 +1.1 1.5 hypothetical protein compare
BWI76_RS07185 +1.1 2.1 hypothetical protein compare
BWI76_RS21340 +1.0 2.8 SoxR reducing system protein RseC compare
BWI76_RS19540 +1.0 1.1 multidrug transporter permease compare
BWI76_RS09305 +1.0 2.0 hypothetical protein compare
BWI76_RS07465 +0.9 2.0 TetR family transcriptional regulator compare
BWI76_RS12985 +0.9 2.3 transcriptional regulator compare
BWI76_RS12090 +0.9 1.5 HNH endonuclease compare
BWI76_RS26085 +0.9 1.4 3-dehydroquinate synthase compare
BWI76_RS11750 +0.9 2.3 chitooligosaccharide deacetylase compare
BWI76_RS13600 +0.9 2.3 hypothetical protein compare
BWI76_RS23970 +0.9 2.0 mechanosensitive ion channel protein MscS compare
BWI76_RS11430 +0.9 1.3 lipoprotein compare
BWI76_RS01545 +0.9 1.8 thiamine biosynthesis protein ThiS compare
BWI76_RS21075 +0.9 1.9 membrane protein compare
BWI76_RS00400 +0.8 1.6 glutamine synthetase compare
BWI76_RS10510 +0.8 3.8 OHCU decarboxylase compare
BWI76_RS24080 +0.8 2.1 DUF179 domain-containing protein compare
BWI76_RS11640 +0.8 3.1 ABC transporter membrane protein compare
BWI76_RS08380 +0.7 1.5 endonuclease VIII compare
BWI76_RS15050 +0.7 1.9 sugar transporter compare
BWI76_RS17675 +0.7 1.0 hypothetical protein compare
BWI76_RS08980 +0.7 1.3 DNA starvation/stationary phase protection protein compare
BWI76_RS20360 +0.7 1.1 cell division protein DedD compare
BWI76_RS25000 +0.7 2.0 malonate decarboxylase acyl carrier protein compare
BWI76_RS07740 +0.7 1.3 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS20730 +0.7 1.7 hypothetical protein compare
BWI76_RS13170 +0.7 1.5 methyltransferase compare
BWI76_RS10530 +0.7 2.0 GntR family transcriptional regulator with compare
BWI76_RS24575 +0.7 1.4 hypothetical protein compare
BWI76_RS02860 +0.7 1.0 glycine dehydrogenase compare
BWI76_RS06475 +0.7 1.4 protoheme IX farnesyltransferase compare
BWI76_RS06815 +0.7 2.4 adenine phosphoribosyltransferase compare
BWI76_RS12465 +0.7 1.0 phage shock protein D compare
BWI76_RS17655 +0.7 4.0 MFS transporter compare
BWI76_RS19310 +0.7 1.4 ABC transporter permease compare
BWI76_RS15035 +0.7 1.3 metal ABC transporter permease compare
BWI76_RS22640 +0.7 1.2 hypothetical protein compare
BWI76_RS24500 +0.7 1.4 urease subunit gamma compare
BWI76_RS16220 +0.7 1.8 hypothetical protein compare
BWI76_RS17970 +0.7 1.2 zinc metalloprotease HtpX compare
BWI76_RS16035 +0.6 1.5 biotin-independent malonate decarboxylase subunit beta compare
BWI76_RS17280 +0.6 2.6 patatin family protein compare
BWI76_RS09825 +0.6 1.8 envelope biogenesis factor ElyC compare
BWI76_RS06080 +0.6 1.7 taurine dioxygenase compare
BWI76_RS06070 +0.6 1.6 taurine transporter ATP-binding subunit compare
BWI76_RS11845 +0.6 1.1 tryptophan synthase subunit beta compare
BWI76_RS10560 +0.6 3.6 gamma-glutamyltransferase compare
BWI76_RS08215 +0.6 2.2 glucosamine-6-phosphate deaminase compare
BWI76_RS20880 +0.6 1.7 esterase compare
BWI76_RS05655 +0.6 2.6 hypothetical protein compare
BWI76_RS15920 +0.6 1.1 hypothetical protein compare
BWI76_RS14715 +0.6 2.5 type I methionyl aminopeptidase compare
BWI76_RS11815 +0.6 1.5 hypothetical protein compare
BWI76_RS15205 +0.6 2.5 succinate-semialdehyde dehydrogenase compare
BWI76_RS07985 +0.6 1.0 fluoride ion transporter CrcB compare
BWI76_RS25480 +0.6 1.8 ribonuclease E/G compare
BWI76_RS17330 +0.6 2.1 nitrate reductase subunit beta compare
BWI76_RS08310 +0.6 2.3 potassium-transporting ATPase subunit C compare
BWI76_RS13730 +0.6 1.7 hypothetical protein compare
BWI76_RS18130 +0.6 2.3 zinc ABC transporter substrate-binding protein compare
BWI76_RS01535 +0.6 2.9 thiazole synthase compare
BWI76_RS16290 +0.6 2.9 Mal regulon transcriptional regulator MalI compare
BWI76_RS01010 +0.6 2.0 uridine phosphorylase compare
BWI76_RS05325 +0.6 2.7 hypothetical protein compare
BWI76_RS18550 +0.6 1.3 tRNA-Asn compare
BWI76_RS06885 +0.6 1.3 TonB family protein compare
BWI76_RS06800 +0.6 1.1 DUF2496 domain-containing protein compare
BWI76_RS18165 +0.6 1.3 NUDIX pyrophosphatase compare
BWI76_RS15360 +0.6 1.5 hypothetical protein compare
BWI76_RS08765 +0.6 2.0 8-amino-7-oxononanoate synthase compare
BWI76_RS01565 +0.6 1.7 NADH pyrophosphatase compare
BWI76_RS26105 +0.6 1.7 hypothetical protein compare
BWI76_RS24770 +0.6 2.4 hypothetical protein compare
BWI76_RS15975 +0.6 0.8 hypothetical protein compare
BWI76_RS08770 +0.6 2.6 malonyl-ACP O-methyltransferase BioC compare
BWI76_RS11635 +0.6 1.3 ABC transporter compare
BWI76_RS06340 +0.6 1.1 hypothetical protein compare
BWI76_RS11680 +0.6 1.7 succinylglutamate-semialdehyde dehydrogenase compare
BWI76_RS14835 +0.6 1.2 hypothetical protein compare
BWI76_RS20605 +0.5 2.3 purine-nucleoside phosphorylase compare
BWI76_RS10540 +0.5 1.6 allantoinase compare
BWI76_RS01120 +0.5 2.2 O-antigen translocase compare
BWI76_RS00720 +0.5 1.9 DNA-binding response regulator compare
BWI76_RS08650 +0.5 1.4 molybdate ABC transporter permease compare
BWI76_RS17375 +0.5 1.7 nitrate ABC transporter, permease protein compare
BWI76_RS03025 +0.5 2.5 N-acetyltransferase compare
BWI76_RS00940 +0.5 2.8 transcriptional regulator HdfR compare
BWI76_RS11235 +0.5 0.7 hypothetical protein compare
BWI76_RS24110 +0.5 1.1 YggU family protein compare
BWI76_RS13215 +0.5 0.9 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS15060 +0.5 1.4 MarR family transcriptional regulator compare
BWI76_RS16805 +0.5 1.2 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS17290 +0.5 1.9 formyltetrahydrofolate deformylase compare
BWI76_RS21390 +0.5 1.8 thiol disulfide reductase thioredoxin compare
BWI76_RS13245 +0.5 1.0 DNA-damage-inducible protein I compare
BWI76_RS01350 +0.5 0.6 NAD(P)H-flavin reductase compare
BWI76_RS15150 +0.5 1.5 outer membrane efflux protein compare
BWI76_RS26750 +0.5 2.7 PfkB domain-containing protein compare
BWI76_RS20695 +0.5 1.5 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS15030 +0.5 1.9 ABC transporter compare
BWI76_RS10760 +0.5 2.4 nitroreductase family protein compare
BWI76_RS19850 +0.5 1.4 tRNA-Pro compare
BWI76_RS08750 +0.5 1.1 kinase inhibitor compare
BWI76_RS10330 +0.5 1.6 TetR family transcriptional regulator compare
BWI76_RS21465 +0.5 2.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS19130 +0.5 2.2 3-methyladenine DNA glycosylase 2 compare
BWI76_RS26190 +0.5 2.6 glycerol-3-phosphate dehydrogenase compare
BWI76_RS15970 +0.5 1.9 carboxypeptidase M32 compare
BWI76_RS11610 +0.5 1.7 glutamate dehydrogenase compare
BWI76_RS14305 +0.5 1.7 metallophosphoesterase compare
BWI76_RS16825 +0.5 2.4 heme ABC transporter compare
BWI76_RS00800 +0.5 2.3 LysR family transcriptional regulator compare
BWI76_RS25960 +0.5 1.8 NUDIX hydrolase compare
BWI76_RS17410 +0.5 1.2 sodium-potassium/proton antiporter ChaA compare
BWI76_RS19215 +0.5 1.2 proline-specific peptidase compare
BWI76_RS26575 +0.5 2.6 universal stress protein B compare
BWI76_RS13175 +0.5 1.0 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS16860 +0.5 2.2 acyl-CoA dehydrogenase compare
BWI76_RS24240 +0.5 1.6 hypothetical protein compare
BWI76_RS21905 +0.5 1.3 class II aldolase compare
BWI76_RS10040 +0.5 1.3 heat-shock protein HspQ compare
BWI76_RS09325 +0.5 2.7 putative bacteriophage tail completion protein compare
BWI76_RS10770 +0.5 1.8 pyrimidine utilization protein C compare
BWI76_RS23015 +0.5 1.2 cobalt transporter ATP-binding subunit compare
BWI76_RS08315 +0.5 1.3 K+-transporting ATPase subunit B compare
BWI76_RS02865 +0.5 1.7 hypothetical protein compare
BWI76_RS17770 +0.5 0.9 isomerase/hydrolase compare
BWI76_RS22420 +0.5 2.0 LacI family transcriptional regulator compare
BWI76_RS23945 +0.5 2.0 methylmalonyl-CoA decarboxylase compare
BWI76_RS17200 +0.5 1.0 hypothetical protein compare
BWI76_RS04980 +0.5 1.7 hypothetical protein compare
BWI76_RS23155 +0.5 1.9 microcompartment protein PduM compare
BWI76_RS18855 +0.5 1.4 cysteine desulfurase NifS compare
BWI76_RS24515 +0.5 2.1 urease accessory protein UreE compare
BWI76_RS09145 +0.5 1.0 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS17660 +0.5 2.1 AraC/XylS familytranscription regulator compare
BWI76_RS20900 +0.5 0.8 outer membrane protein assembly factor BamC compare
BWI76_RS25935 +0.5 2.6 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS21235 +0.5 0.9 hypothetical protein compare
BWI76_RS11370 +0.5 1.5 iron-dicitrate transporter subunit FecD compare
BWI76_RS05975 +0.5 2.2 ABC transporter ATP-binding protein compare
BWI76_RS17830 +0.5 2.1 ABC transporter ATP-binding protein compare
BWI76_RS04560 +0.5 1.6 holo-ACP synthase CitX compare
BWI76_RS01365 +0.5 3.1 multifunctional fatty acid oxidation complex subunit alpha compare
BWI76_RS06950 +0.5 2.6 ABC transporter ATP-binding protein compare
BWI76_RS21345 +0.5 1.0 sigma-E factor regulatory protein RseB compare
BWI76_RS05025 +0.5 2.1 2'-5' RNA ligase compare
BWI76_RS19985 +0.5 2.2 MFS transporter compare
BWI76_RS06060 +0.5 2.1 DNA-binding response regulator compare
BWI76_RS13805 +0.4 1.9 inorganic diphosphatase compare
BWI76_RS15185 +0.4 1.1 N-acetyltransferase compare
BWI76_RS21165 +0.4 1.1 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS03075 +0.4 2.5 5-deoxy-D-glucuronate isomerase (EC 5.3.1.30) (from data) compare
BWI76_RS09470 +0.4 1.8 putrescine ABC transporter permease compare
BWI76_RS19495 +0.4 0.8 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS10640 +0.4 1.3 AraC family transcriptional regulator compare
BWI76_RS13360 +0.4 2.3 benzoate transporter compare
BWI76_RS21980 +0.4 1.7 hypothetical protein compare
BWI76_RS21385 +0.4 1.9 tRNA/rRNA methyltransferase compare
BWI76_RS09590 +0.4 3.3 ATP-dependent OLD family endonuclease compare
BWI76_RS15985 +0.4 1.5 LysR family transcriptional regulator compare
BWI76_RS16095 +0.4 2.3 thiamine biosynthesis protein ApbE compare
BWI76_RS10665 +0.4 1.3 PTS system fructose-like transporter subunit EIIB compare
BWI76_RS01725 +0.4 2.6 PTS mannose/fructose/sorbose family transporter subunit IID compare
BWI76_RS19750 +0.4 1.7 elongation factor P-like protein YeiP compare
BWI76_RS27955 +0.4 2.3 sugar-phosphatase compare
BWI76_RS23265 +0.4 1.2 hypothetical protein compare
BWI76_RS24885 +0.4 1.2 PTS galactitol transporter subunit IIB compare
BWI76_RS04975 +0.4 2.1 PTS fructose subfamily transporter subunit IIA compare
BWI76_RS04840 +0.4 1.3 prepilin peptidase-dependent pilin compare
BWI76_RS08330 +0.4 1.0 hypothetical protein compare
BWI76_RS13590 +0.4 0.9 hypothetical protein compare
BWI76_RS21100 +0.4 1.6 nucleoside-diphosphate kinase compare
BWI76_RS05205 +0.4 1.7 type I methionyl aminopeptidase compare
BWI76_RS25285 +0.4 0.6 HPr family phosphocarrier protein compare
BWI76_RS06430 +0.4 2.7 hypothetical protein compare
BWI76_RS20815 +0.4 2.7 ethanolamine utilization protein EutQ compare
BWI76_RS02610 +0.4 2.4 transcriptional regulator compare
BWI76_RS26015 +0.4 1.6 DUF2559 domain-containing protein compare
BWI76_RS20055 +0.4 2.0 2-succinylbenzoate-CoA ligase compare
BWI76_RS05450 +0.4 0.4 ribonuclease HI compare
BWI76_RS15310 +0.4 2.5 MFS transporter compare
BWI76_RS27785 +0.4 3.0 hexose-6-phosphate transporter; deoxyribose-5-phosphate or dAMP transporter (from data) compare
BWI76_RS14170 +0.4 1.4 hypothetical protein compare
BWI76_RS19140 +0.4 2.2 citrate (Si)-synthase compare
BWI76_RS12150 +0.4 1.1 DNA damage-inducible protein I compare
BWI76_RS01230 +0.4 2.9 chloramphenicol resistance permease RarD compare
BWI76_RS23005 +0.4 1.6 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS13630 +0.4 2.5 ABC transporter compare
BWI76_RS14470 +0.4 1.5 L-serine ammonia-lyase compare
BWI76_RS10055 +0.4 1.3 AraC family transcriptional regulator compare
BWI76_RS20460 +0.4 2.1 acetyl-CoA C-acyltransferase FadI compare
BWI76_RS24665 +0.4 1.2 LsrR family transcriptional regulator compare
BWI76_RS05430 +0.4 2.3 UbiE/COQ5 family methyltransferase compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in phage experiments