Experiment set36IT013 for Klebsiella michiganensis M5al

200 most detrimental genes:

gene	name	fitness	t score	description
BWI76_RS19905		+6.6	36.1	OmpK36 porin
BWI76_RS27310		+6.3	37.2	glycosyltransferase
BWI76_RS16215		+5.3	27.3	hypothetical protein
BWI76_RS19000		+4.5	17.7	acyltransferase
BWI76_RS21070		+3.6	5.5	outer membrane protein assembly factor BamB
BWI76_RS19010		+3.4	7.7	polysaccharide pyruvyl transferase yvff
BWI76_RS05450		+3.2	2.4	ribonuclease HI
BWI76_RS11190		+3.2	7.2	putative TetR/AcrR family transcriptional regulatory protein
BWI76_RS15690		+2.9	8.5	hypothetical protein
BWI76_RS16210		+2.9	2.0	hypothetical protein
BWI76_RS05015		+2.9	7.8	transcriptional regulator
BWI76_RS19070		+2.9	22.6	rhamnosyltransferase
BWI76_RS19075		+2.8	23.8	UDP-phosphate galactose phosphotransferase
BWI76_RS15620		+2.7	4.9	hypothetical protein
BWI76_RS19035		+2.7	11.3	dTDP-rhamnosyl transferase
BWI76_RS19080		+2.6	22.5	tyrosine autokinase
BWI76_RS19085		+2.5	19.0	protein-tyrosine-phosphatase
BWI76_RS23480		+2.5	11.2	EAL domain-containing protein
BWI76_RS19090		+2.5	13.9	polysaccharide export protein Wza
BWI76_RS25600		+2.5	2.9	tRNA-Thr
BWI76_RS19045		+2.4	13.8	capsular polysaccharide biosynthesis protein
BWI76_RS17040		+2.3	8.3	GlsB/YeaQ/YmgE family stress response membrane protein
BWI76_RS17720		+2.3	0.9	muramoyltetrapeptide carboxypeptidase
BWI76_RS04715		+2.3	1.8	division/cell wall cluster transcriptional repressor MraZ
BWI76_RS19040		+2.2	9.7	hypothetical protein
BWI76_RS21350		+2.1	3.2	anti-RNA polymerase sigma factor SigE
BWI76_RS26670		+2.1	10.2	two-component sensor histidine kinase
BWI76_RS19050		+1.9	11.8	NAD(P)-dependent oxidoreductase
BWI76_RS01630		+1.9	2.2	16S ribosomal RNA
BWI76_RS08620		+1.9	5.2	galactose-1-phosphate uridylyltransferase
BWI76_RS21165		+1.9	4.5	Fe-S cluster assembly transcriptional regulator IscR
BWI76_RS08615		+1.9	5.8	galactokinase
BWI76_RS04305		+1.7	1.9	molecular chaperone DnaJ
BWI76_RS16520		+1.7	8.3	Bcr/CflA family multidrug efflux MFS transporter
BWI76_RS16360		+1.7	2.0	electron transport complex subunit RsxB
BWI76_RS15950		+1.7	1.5	dethiobiotin synthase
BWI76_RS26665		+1.6	2.3	DNA-binding response regulator
BWI76_RS06325		+1.6	2.6	hypothetical protein
BWI76_RS03815		+1.6	5.7	hypothetical protein
BWI76_RS18130		+1.6	4.7	zinc ABC transporter substrate-binding protein
BWI76_RS11060		+1.6	2.7	septum formation inhibitor Maf
BWI76_RS18360		+1.6	2.3	aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein
BWI76_RS19055		+1.5	9.9	dTDP-4-dehydrorhamnose 3,5-epimerase
BWI76_RS24055		+1.5	3.8	MFS transporter
BWI76_RS19935		+1.5	2.5	hypothetical protein
BWI76_RS10910		+1.5	3.3	hypothetical protein
BWI76_RS22090		+1.5	3.2	transcriptional regulator
BWI76_RS18905		+1.4	3.6	putrescine/spermidine ABC transporter
BWI76_RS25160		+1.4	3.1	transcription elongation factor GreA
BWI76_RS00180		+1.4	2.1	F0F1 ATP synthase subunit epsilon
BWI76_RS03295		+1.4	1.5	transposase
BWI76_RS16000		+1.4	1.5	multidrug transporter subunit MdtI
BWI76_RS18550		+1.4	2.2	tRNA-Asn
BWI76_RS08025		+1.3	5.8	septal ring lytic transglycosylase RlpA
BWI76_RS18900		+1.3	3.9	protein NifQ
BWI76_RS19840		+1.3	1.4	hypothetical protein
BWI76_RS18165		+1.3	1.6	NUDIX pyrophosphatase
BWI76_RS12825		+1.3	2.4	hypothetical protein
BWI76_RS23015		+1.3	1.9	cobalt transporter ATP-binding subunit
BWI76_RS16675		+1.3	1.8	ABC transporter
BWI76_RS06475		+1.3	1.9	protoheme IX farnesyltransferase
BWI76_RS21340		+1.3	0.9	SoxR reducing system protein RseC
BWI76_RS05260		+1.3	2.4	chaperone
BWI76_RS18575		+1.3	1.6	transcriptional regulator
BWI76_RS09255		+1.3	1.8	hypothetical protein
BWI76_RS11285		+1.2	1.2	transcriptional regulator
BWI76_RS15415		+1.2	1.9	LacI family transcriptional regulator
BWI76_RS25870		+1.2	2.0	elongation factor Tu
BWI76_RS03825		+1.2	2.7	4-hydroxyphenylacetate 3-monooxygenase
BWI76_RS06500		+1.2	8.4	muropeptide transporter AmpG
BWI76_RS17970		+1.2	1.8	zinc metalloprotease HtpX
BWI76_RS16195		+1.2	1.8	hypothetical protein
BWI76_RS24770		+1.2	1.9	hypothetical protein
BWI76_RS11580		+1.2	2.3	L-asparaginase 1
BWI76_RS19130		+1.2	2.5	3-methyladenine DNA glycosylase 2
BWI76_RS06235		+1.2	3.2	PAS domain-containing sensor histidine kinase
BWI76_RS15940		+1.2	2.2	DMSO reductase maturation protein DsmD
BWI76_RS09645		+1.2	0.5	thioredoxin-disulfide reductase
BWI76_RS20940		+1.2	1.7	uracil/xanthine transporter
BWI76_RS00940		+1.2	7.0	transcriptional regulator HdfR
BWI76_RS06490		+1.2	2.4	cytochrome ubiquinol oxidase subunit I
BWI76_RS19865		+1.2	2.4	ecotin
BWI76_RS12450		+1.2	3.6	phage shock protein PspA
BWI76_RS00225		+1.2	4.8	16S rRNA methyltransferase G
BWI76_RS18140		+1.2	3.4	zinc ABC transporter permease
BWI76_RS00290		+1.2	4.4	Ribokinase (EC 2.7.1.15) (from data)
BWI76_RS20155		+1.2	2.1	NADH-quinone oxidoreductase subunit I
BWI76_RS24740		+1.2	2.7	GntR family transcriptional regulator
BWI76_RS17920		+1.1	2.4	23S rRNA (guanine(745)-N(1))-methyltransferase
BWI76_RS15920		+1.1	1.5	hypothetical protein
BWI76_RS15190		+1.1	4.0	GGDEF domain-containing protein
BWI76_RS21370		+1.1	1.5	ATP-dependent RNA helicase SrmB
BWI76_RS11170		+1.1	1.3	hypothetical protein
BWI76_RS04530		+1.1	1.0	peptidylprolyl isomerase SurA
BWI76_RS24035		+1.1	2.9	hypothetical protein
BWI76_RS25480		+1.1	1.9	ribonuclease E/G
BWI76_RS02180		+1.1	2.0	hypothetical protein
BWI76_RS06745		+1.1	2.2	N-acetyltransferase GCN5
BWI76_RS09935		+1.1	2.7	paraquat-inducible membrane protein A
BWI76_RS11515		+1.1	1.1	peptide-methionine (R)-S-oxide reductase
BWI76_RS08600		+1.1	1.9	3-deoxy-7-phosphoheptulonate synthase
BWI76_RS01890		+1.1	2.8	transcriptional regulator Zur
BWI76_RS20385		+1.1	3.4	aspartate-semialdehyde dehydrogenase
BWI76_RS06120		+1.1	1.7	membrane protein
BWI76_RS09145		+1.1	1.7	serine-type D-Ala-D-Ala carboxypeptidase
BWI76_RS17310		+1.1	2.5	AsnC family transcriptional regulator
BWI76_RS23320		+1.1	1.6	hypothetical protein
BWI76_RS12495		+1.1	1.4	2-Cys peroxiredoxin
BWI76_RS06470		+1.1	1.9	hypothetical protein
BWI76_RS00120		+1.1	3.3	glucosamine-6-phosphate deaminase
BWI76_RS18295		+1.1	4.6	tyrosine transporter TyrP
BWI76_RS26590		+1.1	2.5	transcriptional regulator
BWI76_RS10035		+1.1	1.7	hypothetical protein
BWI76_RS11135		+1.1	2.4	ferric-rhodotorulic acid/ferric-coprogen receptor FhuE
BWI76_RS19470		+1.1	2.1	DNA-binding response regulator
BWI76_RS22420		+1.0	2.6	LacI family transcriptional regulator
BWI76_RS00065		+1.0	4.2	MurR/RpiR family transcriptional regulator
BWI76_RS10945		+1.0	2.3	SecY/SecA suppressor protein
BWI76_RS13675		+1.0	4.4	TetR family transcriptional regulator
BWI76_RS20720		+1.0	1.0	hypothetical protein
BWI76_RS03810		+1.0	3.8	GTPase
BWI76_RS15850		+1.0	1.3	DUF1317 domain-containing protein
BWI76_RS17980		+1.0	2.2	RNA chaperone ProQ
BWI76_RS09710		+1.0	2.8	transketolase
BWI76_RS09450		+1.0	1.8	30S ribosomal protein S6--L-glutamate ligase
BWI76_RS27855		+1.0	2.3	D-serine transporter DsdX
BWI76_RS23325		+1.0	1.5	hypothetical protein
BWI76_RS06540		+1.0	3.2	DNA-binding protein HU-beta
BWI76_RS03820		+1.0	5.1	carbon starvation protein A
BWI76_RS08275		+1.0	0.8	LexA regulated protein
BWI76_RS08110		+1.0	1.9	glutamate/aspartate ABC transporter substrate-binding protein
BWI76_RS00075		+1.0	3.7	N-acetylmannosamine-6-phosphate 2-epimerase
BWI76_RS02865		+1.0	1.5	hypothetical protein
BWI76_RS23240		+1.0	1.4	exonuclease V subunit gamma
BWI76_RS22640		+1.0	1.3	hypothetical protein
BWI76_RS17765		+1.0	1.3	hypothetical protein
BWI76_RS01080		+1.0	4.5	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
BWI76_RS15130		+1.0	2.4	hypothetical protein
BWI76_RS21385		+1.0	4.5	tRNA/rRNA methyltransferase
BWI76_RS08405		+1.0	1.6	succinate dehydrogenase flavoprotein subunit
BWI76_RS04705		+1.0	3.1	DNA-binding transcriptional regulator FruR
BWI76_RS14410		+1.0	1.4	hypothetical protein
BWI76_RS11565		+1.0	5.7	DeoR family transcriptional regulator
BWI76_RS13805		+1.0	2.6	inorganic diphosphatase
BWI76_RS21560		+1.0	3.2	DNA repair protein RecN
BWI76_RS25630		+1.0	2.8	hypothetical protein
BWI76_RS11125		+1.0	1.1	metal-dependent hydrolase
BWI76_RS21690		+1.0	1.3	hypothetical protein
BWI76_RS21325		+1.0	1.3	hypothetical protein
BWI76_RS06775		+0.9	5.3	multidrug efflux RND transporter permease subunit
BWI76_RS25705		+0.9	2.1	hypothetical protein
BWI76_RS08745		+0.9	3.2	proline-specific permease
BWI76_RS23250		+0.9	2.8	hypothetical protein
BWI76_RS06460		+0.9	2.5	shikimate dehydrogenase
BWI76_RS21565		+0.9	0.7	outer membrane protein assembly factor BamE
BWI76_RS11010		+0.9	2.1	30S ribosomal protein S5 alanine N-acetyltransferase
BWI76_RS11105		+0.9	1.5	aminodeoxychorismate lyase
BWI76_RS07620		+0.9	3.1	transcriptional regulator BetI
BWI76_RS23830		+0.9	3.2	hypothetical protein
BWI76_RS16375		+0.9	2.2	electron transport complex subunit G
BWI76_RS20145		+0.9	1.5	NADH-quinone oxidoreductase subunit K
BWI76_RS07305		+0.9	2.5	sucrose operon repressor
BWI76_RS21245		+0.9	3.7	nitrogen regulatory protein P-II
BWI76_RS09650		+0.9	3.8	hypothetical protein
BWI76_RS17780		+0.9	3.7	septum formation inhibitor
BWI76_RS12875		+0.9	2.5	bifunctional deaminase-reductase
BWI76_RS00420		+0.9	2.3	hypothetical protein
BWI76_RS08495		+0.9	2.7	cytochrome bd-I ubiquinol oxidase subunit I
BWI76_RS09730		+0.9	1.2	pyruvate formate lyase 1-activating protein
BWI76_RS20150		+0.9	1.3	NADH:ubiquinone oxidoreductase subunit J
BWI76_RS12515		+0.9	1.7	protease
BWI76_RS25545		+0.9	2.0	hypothetical protein
BWI76_RS05205		+0.9	2.9	type I methionyl aminopeptidase
BWI76_RS07780		+0.9	1.2	hypothetical protein
BWI76_RS15730		+0.9	1.8	hypothetical protein
BWI76_RS26245		+0.9	1.6	transcriptional regulator
BWI76_RS11780		+0.9	1.4	2-deoxyglucose-6-phosphatase
BWI76_RS14075		+0.9	0.7	TetR family transcriptional regulator
BWI76_RS24920		+0.9	2.0	YraN family protein
BWI76_RS04595		+0.9	2.0	DNA-binding transcriptional regulator AraC
BWI76_RS13205		+0.9	2.7	hypothetical protein
BWI76_RS02610		+0.9	3.1	transcriptional regulator
BWI76_RS24270		+0.9	1.4	membrane protein
BWI76_RS11520		+0.9	0.9	hypothetical protein
BWI76_RS06545		+0.9	1.7	peptidylprolyl isomerase
BWI76_RS27790		+0.9	5.0	MFS transporter family glucose-6-phosphate receptor UhpC
BWI76_RS11230		+0.9	1.1	NAD-dependent deacylase
BWI76_RS24030		+0.9	5.2	arginine decarboxylase
BWI76_RS24240		+0.9	1.8	hypothetical protein
BWI76_RS08040		+0.9	1.7	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
BWI76_RS25700		+0.9	4.4	heavy metal-responsive transcriptional regulator
BWI76_RS16965		+0.9	0.8	murein lipoprotein
BWI76_RS08840		+0.9	2.5	hypothetical protein
BWI76_RS08260		+0.9	2.2	LysR family transcriptional regulator
BWI76_RS20140		+0.9	3.8	NADH-quinone oxidoreductase subunit L
BWI76_RS08645		+0.9	1.3	molybdate ABC transporter substrate-binding protein
BWI76_RS13195		+0.9	1.2	glutamate dehydrogenase
BWI76_RS06295		+0.9	2.9	S-adenosylmethionine:tRNA ribosyltransferase-isomerase
BWI76_RS16365		+0.9	4.5	electron transport complex subunit RsxC
BWI76_RS24480		+0.8	4.1	undecaprenyl-diphosphatase

Specific Phenotypes

For 7 genes in this experiment