Experiment set36IT009 for Klebsiella michiganensis M5al

200 most important genes:

gene	name	fitness	t score	description
BWI76_RS08720		-5.4	-2.4	imidazolonepropionase
BWI76_RS20750		-4.8	-1.2	carboxysome structural protein EutK
BWI76_RS20380		-4.5	-1.2	tRNA pseudouridine(38-40) synthase TruA
BWI76_RS16955		-4.3	-1.1	hypothetical protein
BWI76_RS26085		-3.9	-1.7	3-dehydroquinate synthase
BWI76_RS15845		-3.9	-1.0	hypothetical protein
BWI76_RS19375		-3.7	-2.2	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
BWI76_RS11525		-3.7	-1.9	HNH endonuclease
BWI76_RS01210		-3.6	-1.6	tyrosine recombinase XerC
BWI76_RS15015		-3.5	-1.3	DUF2132 domain-containing protein
BWI76_RS18165		-3.2	-1.1	NUDIX pyrophosphatase
BWI76_RS03665		-3.2	-1.6	ABC transporter ATP-binding protein
BWI76_RS19495		-3.1	-1.1	ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein
BWI76_RS13330		-3.1	-1.1	tellurite resistance methyltransferase TehB
BWI76_RS08520		-3.0	-1.7	colicin transporter TolQ
BWI76_RS23885		-2.9	-1.0	2-octaprenylphenol hydroxylase
BWI76_RS19325		-2.9	-1.4	mandelate racemase
BWI76_RS12470		-2.9	-1.3	thiosulfate sulfurtransferase PspE
BWI76_RS13250		-2.8	-1.0	cytochrome b561
BWI76_RS08405		-2.8	-2.7	succinate dehydrogenase flavoprotein subunit
BWI76_RS16200		-2.7	-2.0	NAD(P) transhydrogenase subunit beta
BWI76_RS21370		-2.7	-0.9	ATP-dependent RNA helicase SrmB
BWI76_RS17565		-2.5	-1.5	hypothetical protein
BWI76_RS11635		-2.5	-1.2	ABC transporter
BWI76_RS17300		-2.5	-0.9	tRNA-Tyr
BWI76_RS14820		-2.4	-1.2	LysR family transcriptional regulator
BWI76_RS16140		-2.4	-1.8	3-oxoadipate CoA-transferase
BWI76_RS22475		-2.4	-2.6	heme ABC transporter ATP-binding protein
BWI76_RS10955		-2.4	-1.4	hypothetical protein
BWI76_RS15350		-2.2	-0.9	hypothetical protein
BWI76_RS15195		-2.2	-1.3	DUF4186 domain-containing protein
BWI76_RS13590		-2.1	-1.7	hypothetical protein
BWI76_RS04655		-2.0	-2.6	shikimate dehydrogenase
BWI76_RS16195		-2.0	-1.2	hypothetical protein
BWI76_RS16335		-2.0	-1.1	division septum protein Blr
BWI76_RS18770		-2.0	-0.9	DNA gyrase inhibitor
BWI76_RS12145		-1.9	-0.9	hypothetical protein
BWI76_RS09645		-1.9	-0.5	thioredoxin-disulfide reductase
BWI76_RS15825		-1.9	-1.3	hypothetical protein
BWI76_RS25920		-1.9	-1.9	peptidylprolyl isomerase
BWI76_RS13560		-1.8	-0.6	amino acid ABC transporter substrate-binding subunit
BWI76_RS09190		-1.8	-2.4	hypothetical protein
BWI76_RS11150		-1.8	-1.2	membrane protein
BWI76_RS16515		-1.7	-1.3	LysR family transcriptional regulator
BWI76_RS12595		-1.7	-2.6	hypothetical protein
BWI76_RS23895		-1.7	-1.1	Xaa-Pro aminopeptidase
BWI76_RS17200		-1.7	-0.9	hypothetical protein
BWI76_RS05810		-1.7	-1.1	hypothetical protein
BWI76_RS17770		-1.7	-1.2	isomerase/hydrolase
BWI76_RS01385		-1.7	-1.7	potassium transporter
BWI76_RS16920		-1.6	-1.1	3-(2,3-dihydroxyphenyl)propionate dioxygenase
BWI76_RS04715		-1.6	-0.8	division/cell wall cluster transcriptional repressor MraZ
BWI76_RS13600		-1.6	-1.7	hypothetical protein
BWI76_RS14035		-1.6	-2.3	ABC transporter ATPase
BWI76_RS12870		-1.6	-1.4	putative phytanoyl-CoA dioxygenase
BWI76_RS10835		-1.6	-1.0	hypothetical protein
BWI76_RS02580		-1.6	-1.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase
BWI76_RS16090		-1.6	-1.4	two-component system response regulator DcuR
BWI76_RS20880		-1.5	-1.7	esterase
BWI76_RS20995		-1.5	-2.6	RNA degradosome polyphosphate kinase
BWI76_RS14170		-1.5	-1.5	hypothetical protein
BWI76_RS20325		-1.5	-2.1	histidine/lysine/arginine/ornithine ABC transporter permease HisM
BWI76_RS15835		-1.5	-1.6	hypothetical protein
BWI76_RS10815		-1.4	-1.5	iron permease
BWI76_RS15675		-1.4	-2.6	hypothetical protein
BWI76_RS27275		-1.4	-4.0	hypothetical protein
BWI76_RS13160		-1.4	-1.0	azoreductase
BWI76_RS14770		-1.4	-0.8	PTS IIA 2 domain protein
BWI76_RS11365		-1.4	-1.5	iron ABC transporter
BWI76_RS17665		-1.4	-1.1	proteasome-type protease
BWI76_RS05465		-1.4	-0.9	amidohydrolase
BWI76_RS15740		-1.4	-1.3	HNH endonuclease
BWI76_RS18410		-1.3	-1.7	drug/metabolite exporter YedA
BWI76_RS01380		-1.3	-3.0	YigZ family protein
BWI76_RS20765		-1.3	-2.5	ethanolamine ammonia lyase large subunit
BWI76_RS08530		-1.3	-1.0	protein TolA
BWI76_RS14365		-1.3	-2.2	transcriptional regulator
BWI76_RS10585		-1.3	-1.3	amino acid ABC transporter ATP-binding protein
BWI76_RS15955		-1.3	-2.0	transcriptional regulator
BWI76_RS20650		-1.3	-0.7	phosphoenolpyruvate--protein phosphotransferase
BWI76_RS01940		-1.3	-1.8	hypothetical protein
BWI76_RS18360		-1.3	-1.0	aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein
BWI76_RS24955		-1.3	-1.7	hypothetical protein
BWI76_RS02220		-1.3	-2.2	carbon-phosphorus lyase subunit PhnH
BWI76_RS17315		-1.3	-1.5	EamA family transporter
BWI76_RS14625		-1.2	-0.6	protein TolA
BWI76_RS05040		-1.2	-2.4	type II secretion system protein N
BWI76_RS27140		-1.2	-2.5	L-selenocysteinyl-tRNA(Sec) synthase
BWI76_RS21235		-1.2	-0.8	hypothetical protein
BWI76_RS14835		-1.2	-0.6	hypothetical protein
BWI76_RS15770		-1.2	-2.3	hypothetical protein
BWI76_RS07385		-1.2	-1.6	short-chain dehydrogenase/reductase SDR
BWI76_RS26095		-1.2	-0.8	shikimate kinase
BWI76_RS16245		-1.2	-2.8	hypothetical protein
BWI76_RS05075		-1.2	-0.9	type II secretion system protein GspG
BWI76_RS07265		-1.2	-1.8	ABC transporter ATP-binding protein
BWI76_RS09255		-1.2	-1.1	hypothetical protein
BWI76_RS01545		-1.2	-1.3	thiamine biosynthesis protein ThiS
BWI76_RS04955		-1.2	-0.8	hypoxanthine phosphoribosyltransferase
BWI76_RS11820		-1.2	-0.6	short-chain dehydrogenase/reductase SDR
BWI76_RS01195		-1.2	-1.7	membrane protein
BWI76_RS07985		-1.2	-0.7	fluoride ion transporter CrcB
BWI76_RS15345		-1.2	-2.4	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase
BWI76_RS07865		-1.2	-1.0	methylthioribulose 1-phosphate dehydratase
BWI76_RS16755		-1.1	-1.2	acetoin reductase
BWI76_RS17895		-1.1	-1.7	PTS mannose/fructose/sorbose transporter subunit IIC
BWI76_RS11675		-1.1	-1.2	arginine N-succinyltransferase
BWI76_RS13290		-1.1	-1.9	protocatechuate 3,4-dioxygenase subunit beta
BWI76_RS15560		-1.1	-3.8	hypothetical protein
BWI76_RS12055		-1.1	-1.2	DNA single-strand annealing protein RecT-like protein
BWI76_RS01170		-1.1	-2.3	uroporphyrinogen-III C-methyltransferase
BWI76_RS07820		-1.1	-1.3	S-methyl-5-thioribose kinase
BWI76_RS16230		-1.1	-1.3	dihydromonapterin reductase
BWI76_RS15605		-1.1	-0.8	hypothetical protein
BWI76_RS06765		-1.1	-1.7	transcriptional regulator
BWI76_RS11335		-1.1	-0.6	tautomerase
BWI76_RS20295		-1.1	-3.3	dihydroneopterin triphosphate 2'-epimerase
BWI76_RS07870		-1.1	-3.4	carbohydrate kinase
BWI76_RS03660		-1.1	-1.8	hypothetical protein
BWI76_RS20785		-1.1	-0.8	ethanolamine utilization protein EutJ
BWI76_RS22960		-1.1	-1.1	YgdI/YgdR family lipoprotein
BWI76_RS12420		-1.1	-0.5	peptide ABC transporter substrate-binding protein SapA
BWI76_RS12400		-1.1	-2.8	TetR family transcriptional regulator
BWI76_RS14650		-1.1	-1.5	helix-turn-helix transcriptional regulator
BWI76_RS18430		-1.1	-1.3	hypothetical protein
BWI76_RS25635		-1.1	-1.5	gamma carbonic anhydrase family protein
BWI76_RS26660		-1.1	-2.7	transcription elongation factor GreB
BWI76_RS12170		-1.1	-1.4	hypothetical protein
BWI76_RS26945		-1.0	-2.5	hypothetical protein
BWI76_RS20430		-1.0	-1.4	penicillin-insensitive murein endopeptidase
BWI76_RS09505		-1.0	-1.0	arginine transporter permease subunit ArtM
BWI76_RS20965		-1.0	-1.9	phosphoribosylformylglycinamidine cyclo-ligase
BWI76_RS02725		-1.0	-0.7	HxlR family transcriptional regulator
BWI76_RS13335		-1.0	-2.3	peptidase T
BWI76_RS27290		-1.0	-3.8	hypothetical protein
BWI76_RS04155		-1.0	-3.0	membrane protein
BWI76_RS04875		-1.0	-2.5	transcriptional regulator PdhR
BWI76_RS12965		-1.0	-2.3	LysR family transcriptional regulator
BWI76_RS15035		-1.0	-0.8	metal ABC transporter permease
BWI76_RS15900		-1.0	-1.7	hypothetical protein
BWI76_RS10530		-1.0	-1.1	GntR family transcriptional regulator with
BWI76_RS11035		-1.0	-1.0	putative LysR-family transcriptional regulator
BWI76_RS05135		-1.0	-1.4	iron-hydroxamate transporter substrate-binding subunit
BWI76_RS16975		-1.0	-2.1	cysteine desufuration protein SufE
BWI76_RS12665		-1.0	-1.1	hypothetical protein
BWI76_RS07680		-1.0	-2.9	transketolase
BWI76_RS16300		-0.9	-1.7	bifunctional beta-cystathionase/maltose regulon regulatory protein
BWI76_RS09530		-0.9	-0.6	hypothetical protein
BWI76_RS12790		-0.9	-0.6	lactate dehydrogenase
BWI76_RS24100		-0.9	-1.4	YggS family pyridoxal phosphate enzyme
BWI76_RS19650		-0.9	-2.3	DNA-binding transcriptional regulator GalS
BWI76_RS26460		-0.9	-2.7	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE
BWI76_RS03540		-0.9	-2.6	tryptophanase leader peptide
BWI76_RS23580		-0.9	-0.8	hypothetical protein
BWI76_RS01060		-0.9	-3.6	guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase
BWI76_RS14225		-0.9	-1.5	anti-ECF sigma factor ChrR
BWI76_RS12520		-0.9	-1.5	hypothetical protein
BWI76_RS14540		-0.9	-0.9	yersiniabactin biosynthetic protein YbtU
BWI76_RS20360		-0.9	-0.6	cell division protein DedD
BWI76_RS18855		-0.9	-1.0	cysteine desulfurase NifS
BWI76_RS15120		-0.9	-1.6	hypothetical protein
BWI76_RS21505		-0.9	-0.6	hypothetical protein
BWI76_RS18580		-0.9	-0.7	hypothetical protein
BWI76_RS11440		-0.9	-0.5	hypothetical protein
BWI76_RS19480		-0.9	-1.4	transcriptional regulator
BWI76_RS21100		-0.9	-1.5	nucleoside-diphosphate kinase
BWI76_RS26280		-0.9	-2.3	hypothetical protein
BWI76_RS17515		-0.9	-1.1	dihydropyrimidinase
BWI76_RS19900		-0.9	-1.7	FAD:protein FMN transferase
BWI76_RS08640		-0.9	-1.0	multidrug efflux pump-associated protein, AcrZ family
BWI76_RS09305		-0.9	-1.4	hypothetical protein
BWI76_RS27600		-0.9	-2.0	tRNA-Sec
BWI76_RS24335		-0.9	-2.2	two-component system response regulator QseB
BWI76_RS18090		-0.9	-1.0	phosphoribosylglycinamide formyltransferase 2
BWI76_RS15830		-0.9	-2.4	hypothetical protein
BWI76_RS13545		-0.9	-0.6	N-acetyltransferase
BWI76_RS12065		-0.9	-1.5	hypothetical protein
BWI76_RS21140		-0.9	-0.8	molecular chaperone HscA
BWI76_RS16635		-0.8	-1.5	carbonate dehydratase
BWI76_RS08375		-0.8	-1.2	pyroglutamyl-peptidase I
BWI76_RS07755		-0.8	-1.4	isochorismatase
BWI76_RS12695		-0.8	-1.4	zinc transporter ZntB
BWI76_RS26000		-0.8	-2.5	aspartate aminotransferase family protein
BWI76_RS17110		-0.8	-0.6	vitamin B12 ABC transporter permease BtuC
BWI76_RS10560		-0.8	-1.5	gamma-glutamyltransferase
BWI76_RS18375		-0.8	-1.6	hypothetical protein
BWI76_RS21490		-0.8	-4.2	GGDEF domain-containing protein
BWI76_RS23915		-0.8	-1.2	5-formyltetrahydrofolate cyclo-ligase
BWI76_RS11395		-0.8	-1.7	RNA polymerase sigma factor FecI
BWI76_RS16830		-0.8	-1.4	ABC transporter
BWI76_RS10500		-0.8	-1.0	flavoprotein monooxygenase
BWI76_RS21680		-0.8	-1.2	antitoxin of the YeeV-YeeU toxin-antitoxin system
BWI76_RS11430		-0.8	-0.5	lipoprotein
BWI76_RS13400		-0.8	-1.2	GntR family transcriptional regulator
BWI76_RS10300		-0.8	-1.6	MFS transporter
BWI76_RS24180		-0.8	-1.1	hypothetical protein
BWI76_RS10280		-0.8	-1.6	polar amino acid ABC transporter permease
BWI76_RS07785		-0.8	-0.9	transcriptional regulator
BWI76_RS14390		-0.8	-0.7	hypothetical protein
BWI76_RS24785		-0.8	-2.7	DUF805 domain-containing protein

Specific Phenotypes

For 14 genes in this experiment