Experiment set32IT052 for Klebsiella michiganensis M5al

200 most detrimental genes:

gene	name	fitness	t score	description
BWI76_RS06980		+5.0	28.4	ureidoglycolate lyase
BWI76_RS22650		+4.3	2.9	lipoprotein NlpD
BWI76_RS06530		+3.6	18.1	ATP-dependent Clp protease ATP-binding subunit ClpX
BWI76_RS07780		+3.4	6.6	hypothetical protein
BWI76_RS06525		+3.4	13.4	ATP-dependent Clp protease proteolytic subunit
BWI76_RS12925		+3.0	1.4	efflux transporter periplasmic adaptor subunit
BWI76_RS17665		+3.0	1.6	proteasome-type protease
BWI76_RS19575		+2.7	1.1	maleylacetoacetate isomerase
BWI76_RS08655		+2.6	1.8	molybdenum ABC transporter ATP-binding protein
BWI76_RS27395		+2.4	2.0	hypothetical protein
BWI76_RS23055		+2.4	1.3	cobalamin biosynthesis protein CbiG
BWI76_RS20380		+2.4	2.7	tRNA pseudouridine(38-40) synthase TruA
BWI76_RS23895		+2.3	2.4	Xaa-Pro aminopeptidase
BWI76_RS08215		+2.3	1.0	glucosamine-6-phosphate deaminase
BWI76_RS04900		+2.3	1.7	DUF2950 domain-containing protein
BWI76_RS27950		+2.3	1.3	transcriptional regulator
BWI76_RS17785		+2.3	2.0	septum site-determining protein MinD
BWI76_RS16425		+2.1	2.3	hypothetical protein
BWI76_RS27505		+2.0	1.2	septal ring assembly protein ZapB
BWI76_RS14390		+2.0	2.2	hypothetical protein
BWI76_RS07165		+2.0	1.4	hypothetical protein
BWI76_RS22640		+2.0	1.2	hypothetical protein
BWI76_RS18385		+2.0	2.4	hypothetical protein
BWI76_RS24035		+1.9	2.0	hypothetical protein
BWI76_RS26515		+1.9	1.2	nickel import ATP-binding protein NikD
BWI76_RS18470		+1.9	1.4	hypothetical protein
BWI76_RS20970		+1.9	3.3	phosphoribosylglycinamide formyltransferase
BWI76_RS10560		+1.8	2.0	gamma-glutamyltransferase
BWI76_RS16080		+1.8	1.3	LysR family transcriptional regulator
BWI76_RS06540		+1.8	1.5	DNA-binding protein HU-beta
BWI76_RS09630		+1.8	2.2	leucyl/phenylalanyl-tRNA--protein transferase
BWI76_RS01585		+1.8	3.7	transcriptional regulator
BWI76_RS23610		+1.8	1.8	multidrug transporter subunit MdtN
BWI76_RS26130		+1.7	3.5	ADP compounds hydrolase NudE
BWI76_RS03665		+1.7	1.5	ABC transporter ATP-binding protein
BWI76_RS19480		+1.7	4.8	transcriptional regulator
BWI76_RS00715		+1.7	2.8	two-component sensor histidine kinase
BWI76_RS03195		+1.7	1.1	P4 phage protein
BWI76_RS11040		+1.7	1.3	ribonuclease E
BWI76_RS09530		+1.7	2.0	hypothetical protein
BWI76_RS23515		+1.7	5.2	antibiotic biosynthesis monooxygenase
BWI76_RS13855		+1.6	1.1	peroxiredoxin
BWI76_RS11935		+1.6	1.6	YmiA family putative membrane protein
BWI76_RS27875		+1.5	1.4	membrane protein
BWI76_RS20795		+1.5	1.6	ethanolamine catabolic microcompartment shell protein EutN
BWI76_RS27780		+1.5	2.3	hypothetical protein
BWI76_RS17525		+1.5	3.1	XshC-Cox1-family protein
BWI76_RS22910		+1.5	1.9	flap endonuclease Xni
BWI76_RS08760		+1.5	1.2	biotin synthase
BWI76_RS17975		+1.4	4.2	tail-specific protease
BWI76_RS13785		+1.4	1.6	ABC transporter permease
BWI76_RS11395		+1.4	1.8	RNA polymerase sigma factor FecI
BWI76_RS16555		+1.4	2.0	hypothetical protein
BWI76_RS09535		+1.4	1.3	N-acetylmuramoyl-L-alanine amidase amid
BWI76_RS03175		+1.4	1.2	hypothetical protein
BWI76_RS23905		+1.4	1.5	Z-ring-associated protein
BWI76_RS20565		+1.4	2.1	hypothetical protein
BWI76_RS18755		+1.4	1.8	adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase
BWI76_RS12085		+1.4	1.4	regulatory protein CII from bacteriophage origin
BWI76_RS11060		+1.3	2.3	septum formation inhibitor Maf
BWI76_RS13225		+1.3	1.2	hypothetical protein
BWI76_RS05570		+1.3	1.3	hypothetical protein
BWI76_RS07075		+1.3	1.0	hypothetical protein
BWI76_RS01665		+1.3	1.6	Isocitrate lyase (EC 4.1.3.1) (from data)
BWI76_RS21165		+1.3	2.2	Fe-S cluster assembly transcriptional regulator IscR
BWI76_RS24180		+1.3	2.5	hypothetical protein
BWI76_RS06130		+1.3	1.8	extensin family protein
BWI76_RS21810		+1.3	1.2	universal stress protein
BWI76_RS07690		+1.3	1.3	enterochelin synthetase component D
BWI76_RS24950		+1.3	0.9	hypothetical protein
BWI76_RS10760		+1.3	1.5	nitroreductase family protein
BWI76_RS09960		+1.3	2.5	Lon protease
BWI76_RS21495		+1.3	3.8	outer membrane lipoprotein
BWI76_RS14225		+1.3	1.5	anti-ECF sigma factor ChrR
BWI76_RS00110		+1.3	1.1	adenine permease PurP
BWI76_RS17210		+1.2	1.1	dsDNA-mimic protein
BWI76_RS20020		+1.2	1.3	nucleoside triphosphatase NudI
BWI76_RS18740		+1.2	1.8	HPP family protein
BWI76_RS01235		+1.2	2.3	hypothetical protein
BWI76_RS13715		+1.2	2.8	2-chlorobenzoate 1 2-dioxygenase electron transfer subunit
BWI76_RS17325		+1.2	2.0	nitrate reductase molybdenum cofactor assembly chaperone
BWI76_RS13745		+1.2	1.9	formate dehydrogenase subunit beta
BWI76_RS08825		+1.2	2.9	cyclic pyranopterin monophosphate synthase MoaC
BWI76_RS18575		+1.2	1.2	transcriptional regulator
BWI76_RS22310		+1.2	1.1	hydrogenase 3 small subunit
BWI76_RS00400		+1.2	0.6	glutamine synthetase
BWI76_RS01010		+1.2	1.2	uridine phosphorylase
BWI76_RS23460		+1.2	1.0	hypothetical protein
BWI76_RS26910		+1.2	1.1	hypothetical protein
BWI76_RS23580		+1.2	2.1	hypothetical protein
BWI76_RS08585		+1.2	1.7	nicotinamide riboside transporter PnuC
BWI76_RS12565		+1.2	1.3	SAM-dependent methyltransferase
BWI76_RS26410		+1.1	1.9	membrane protein
BWI76_RS25545		+1.1	1.1	hypothetical protein
BWI76_RS05160		+1.1	2.2	hypothetical protein
BWI76_RS06120		+1.1	1.5	membrane protein
BWI76_RS24665		+1.1	1.1	LsrR family transcriptional regulator
BWI76_RS16645		+1.1	1.5	DeoR family transcriptional regulator
BWI76_RS05555		+1.1	2.9	Crl family RNA polymerase assembly factor
BWI76_RS09155		+1.1	2.2	undecaprenyl-diphosphatase
BWI76_RS21710		+1.1	3.1	nitroreductase
BWI76_RS21995		+1.1	1.0	transcriptional regulator
BWI76_RS14065		+1.1	1.1	hypothetical protein
BWI76_RS14835		+1.1	0.9	hypothetical protein
BWI76_RS16365		+1.1	1.5	electron transport complex subunit RsxC
BWI76_RS03630		+1.1	0.8	LysR family transcriptional regulator
BWI76_RS16490		+1.1	2.0	glutaredoxin
BWI76_RS10845		+1.1	1.7	DNA-binding response regulator
BWI76_RS21075		+1.1	1.0	membrane protein
BWI76_RS23950		+1.1	1.8	succinate CoA transferase
BWI76_RS22130		+1.1	2.4	fructose-1-phosphate/6-phosphogluconate phosphatase
BWI76_RS13850		+1.1	1.8	N-acetyltransferase
BWI76_RS16895		+1.1	0.9	3-(3-hydroxy-phenyl)propionate transporter MhpT
BWI76_RS24730		+1.1	1.2	uronate isomerase
BWI76_RS13485		+1.1	1.2	NADP-dependent oxidoreductase
BWI76_RS11470		+1.1	2.2	sensor domain-containing diguanylate cyclase
BWI76_RS07950		+1.1	1.1	universal stress protein G
BWI76_RS11750		+1.1	2.5	chitooligosaccharide deacetylase
BWI76_RS19580		+1.0	2.3	FAA-hydrolase
BWI76_RS05235		+1.0	0.8	hypothetical protein
BWI76_RS05140		+1.0	0.9	Fe3+-hydroxamate ABC transporter permease FhuB
BWI76_RS17875		+1.0	1.0	L-serine ammonia-lyase
BWI76_RS16830		+1.0	0.8	ABC transporter
BWI76_RS19495		+1.0	1.0	ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein
BWI76_RS03970		+1.0	1.4	PTS mannose/fructose/sorbose family transporter subunit IID
BWI76_RS13635		+1.0	0.8	extracellular solute-binding protein
BWI76_RS18445		+1.0	2.9	glycosyltransferase
BWI76_RS04320		+1.0	1.6	transcriptional activator NhaR
BWI76_RS25285		+1.0	1.0	HPr family phosphocarrier protein
BWI76_RS15730		+1.0	2.8	hypothetical protein
BWI76_RS20940		+1.0	1.7	uracil/xanthine transporter
BWI76_RS26855		+1.0	2.2	cellulose synthase operon protein YhjQ
BWI76_RS23370		+1.0	1.4	aspartate/glutamate racemase
BWI76_RS04965		+1.0	1.6	ABC transporter ATP-binding protein
BWI76_RS09850		+1.0	2.0	L,D-transpeptidase
BWI76_RS11695		+1.0	1.6	ATP-independent periplasmic protein-refolding chaperone
BWI76_RS09075		+1.0	2.2	pyruvate formate lyase-activating protein
BWI76_RS10890		+1.0	2.5	glyoxylate/hydroxypyruvate reductase A
BWI76_RS13275		+1.0	1.7	hypothetical protein
BWI76_RS18390		+1.0	2.2	hypothetical protein
BWI76_RS06810		+1.0	1.7	hypothetical protein
BWI76_RS06805		+1.0	2.1	primosomal replication protein N''
BWI76_RS10505		+1.0	0.9	putative guanine/xanthin permease
BWI76_RS02690		+1.0	2.0	hypothetical protein
BWI76_RS22980		+1.0	3.7	murein transglycosylase A
BWI76_RS27900		+1.0	2.2	DNA damage-inducible protein D
BWI76_RS17180		+1.0	2.3	hypothetical protein
BWI76_RS02270		+1.0	1.5	DSBA oxidoreductase
BWI76_RS21675		+1.0	1.4	hypothetical protein
BWI76_RS10805		+1.0	2.2	hypothetical protein
BWI76_RS00795		+1.0	2.5	carboxymuconolactone decarboxylase
BWI76_RS19325		+1.0	1.5	mandelate racemase
BWI76_RS20720		+1.0	1.2	hypothetical protein
BWI76_RS01515		+0.9	1.2	PTS family cellobiose transporter subunit IIA
BWI76_RS00025		+0.9	0.9	hypothetical protein
BWI76_RS02855		+0.9	1.4	cytochrome B562
BWI76_RS09310		+0.9	2.4	hypothetical protein
BWI76_RS24250		+0.9	1.4	hypothetical protein
BWI76_RS26865		+0.9	2.2	dipeptide ABC transporter ATP-binding protein
BWI76_RS09025		+0.9	0.7	GntR family transcriptional regulator
BWI76_RS04260		+0.9	1.8	peroxide stress protein YaaA
BWI76_RS05070		+0.9	1.3	type II secretion system protein GspH
BWI76_RS10620		+0.9	2.1	hypothetical protein
BWI76_RS13545		+0.9	1.1	N-acetyltransferase
BWI76_RS02605		+0.9	1.3	esterase
BWI76_RS23945		+0.9	2.5	methylmalonyl-CoA decarboxylase
BWI76_RS18075		+0.9	1.3	oligopeptidase B
BWI76_RS02420		+0.9	1.1	entericidin EcnAB
BWI76_RS01850		+0.9	1.3	maltose operon protein MalM
BWI76_RS21375		+0.9	1.2	autonomous glycyl radical cofactor GrcA
BWI76_RS10635		+0.9	2.9	GGDEF domain-containing protein
BWI76_RS19215		+0.9	1.2	proline-specific peptidase
BWI76_RS23320		+0.9	1.2	hypothetical protein
BWI76_RS09470		+0.9	2.3	putrescine ABC transporter permease
BWI76_RS22420		+0.9	0.7	LacI family transcriptional regulator
BWI76_RS27940		+0.9	1.8	2-dehydro-3-deoxy-6-phosphogalactonate aldolase
BWI76_RS03890		+0.9	2.3	hypothetical protein
BWI76_RS15890		+0.9	1.0	Zn-dependent oxidoreductase
BWI76_RS03005		+0.9	1.3	hypothetical protein
BWI76_RS27500		+0.9	2.5	sulfate transporter subunit
BWI76_RS10585		+0.9	2.4	amino acid ABC transporter ATP-binding protein
BWI76_RS02090		+0.9	1.5	membrane protein
BWI76_RS03835		+0.9	1.5	4-hydroxyphenylacetate catabolism regulatory protein HpaA
BWI76_RS22960		+0.9	1.2	YgdI/YgdR family lipoprotein
BWI76_RS16030		+0.9	2.7	malonate decarboxylase acyl carrier protein
BWI76_RS11775		+0.9	1.7	2-deoxy-D-gluconate 3-dehydrogenase
BWI76_RS13135		+0.9	0.9	3-oxoadipyl-CoA thiolase
BWI76_RS17980		+0.9	2.9	RNA chaperone ProQ
BWI76_RS04165		+0.9	2.8	DNA repair protein RadA
BWI76_RS08975		+0.9	1.6	amino acid ABC transporter substrate-binding protein
BWI76_RS11390		+0.9	1.2	iron dicitrate transport regulator FecR
BWI76_RS14030		+0.9	0.6	ABC transporter permease
BWI76_RS09915		+0.9	1.2	cell division protein ZapC
BWI76_RS15045		+0.8	1.7	LysR family transcriptional regulator
BWI76_RS14975		+0.8	1.0	glyoxalase-like domain protein
BWI76_RS22815		+0.8	2.2	hybrid sensor histidine kinase/response regulator
BWI76_RS12895		+0.8	2.4	hypothetical protein
BWI76_RS24170		+0.8	1.4	nucleoside permease
BWI76_RS15215		+0.8	0.7	N-acetyltransferase
BWI76_RS22365		+0.8	2.6	hydrogenase expression/formation protein HypE

Specific Phenotypes

For 3 genes in this experiment