Experiment set32IT048 for Klebsiella michiganensis M5al

200 most detrimental genes:

gene	name	fitness	t score	description
BWI76_RS23140		+5.6	3.1	carboxysome shell protein
BWI76_RS08345		+5.2	2.1	Nif3-like dinuclear metal center protein
BWI76_RS12985		+4.7	14.9	transcriptional regulator
BWI76_RS06525		+4.6	34.1	ATP-dependent Clp protease proteolytic subunit
BWI76_RS19215		+4.4	13.8	proline-specific peptidase
BWI76_RS11150		+4.3	2.3	membrane protein
BWI76_RS05800		+4.3	17.0	phage transcriptional activator, Ogr/delta
BWI76_RS14620		+4.2	19.4	acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase
BWI76_RS06530		+4.1	13.5	ATP-dependent Clp protease ATP-binding subunit ClpX
BWI76_RS22450		+4.0	2.4	selenoprotein W-related protein
BWI76_RS17780		+3.7	2.2	septum formation inhibitor
BWI76_RS21070		+3.7	1.7	outer membrane protein assembly factor BamB
BWI76_RS09290		+3.5	2.4	phage Tail Protein X
BWI76_RS25070		+3.3	6.7	hypothetical protein
BWI76_RS10825		+3.1	1.8	deferrochelatase/peroxidase EfeB
BWI76_RS11040		+2.9	1.2	ribonuclease E
BWI76_RS11820		+2.9	5.9	short-chain dehydrogenase/reductase SDR
BWI76_RS22960		+2.8	1.7	YgdI/YgdR family lipoprotein
BWI76_RS17785		+2.5	2.2	septum site-determining protein MinD
BWI76_RS11365		+2.5	1.7	iron ABC transporter
BWI76_RS24055		+2.4	1.8	MFS transporter
BWI76_RS09310		+2.4	1.3	hypothetical protein
BWI76_RS23735		+2.3	1.3	sugar diacid utilization regulator
BWI76_RS21165		+2.3	5.6	Fe-S cluster assembly transcriptional regulator IscR
BWI76_RS18390		+2.3	2.5	hypothetical protein
BWI76_RS24315		+2.2	2.3	cell division protein FtsP
BWI76_RS09765		+2.2	2.0	metalloprotease
BWI76_RS04770		+2.2	1.4	D-alanine--D-alanine ligase
BWI76_RS02895		+2.1	1.1	hypothetical protein
BWI76_RS13410		+2.1	1.4	polyamine ABC transporter ATP-binding protein
BWI76_RS24225		+2.0	1.4	hypothetical protein
BWI76_RS00885		+2.0	1.4	tRNA (uridine(54)-C5)-methyltransferase TrmA
BWI76_RS06880		+2.0	1.5	biopolymer transport protein ExbD/TolR
BWI76_RS09115		+2.0	1.4	30S ribosomal protein S12 methylthiotransferase RimO
BWI76_RS03285		+2.0	1.3	hypothetical protein
BWI76_RS13730		+2.0	0.9	hypothetical protein
BWI76_RS15770		+1.9	0.9	hypothetical protein
BWI76_RS03190		+1.9	1.3	hypothetical protein
BWI76_RS24765		+1.9	1.7	membrane protein
BWI76_RS05965		+1.8	1.9	hypothetical protein
BWI76_RS25635		+1.8	1.5	gamma carbonic anhydrase family protein
BWI76_RS21780		+1.8	1.6	S-(hydroxymethyl)glutathione synthase
BWI76_RS11345		+1.8	1.1	LysR family transcriptional regulator
BWI76_RS16805		+1.6	3.5	basic amino acid ABC transporter substrate-binding protein
BWI76_RS22955		+1.6	1.3	transcriptional regulator GcvA
BWI76_RS20510		+1.6	2.3	glucokinase
BWI76_RS26620		+1.6	1.9	Fe-S biogenesis protein NfuA
BWI76_RS26355		+1.6	1.5	hypothetical protein
BWI76_RS20290		+1.5	1.8	thiol:disulfide oxidoreductase
BWI76_RS14780		+1.5	1.6	phosphotriesterase
BWI76_RS16975		+1.5	2.1	cysteine desufuration protein SufE
BWI76_RS11755		+1.5	1.2	catalase HPII
BWI76_RS13220		+1.5	1.9	N-acetyltransferase
BWI76_RS15755		+1.5	2.2	hypothetical protein
BWI76_RS06935		+1.5	1.6	co-chaperone YbbN
BWI76_RS24825		+1.5	0.8	2-hydroxy-3-oxopropionate reductase
BWI76_RS24660		+1.4	1.5	autoinducer 2 ABC transporter ATP-binding protein LsrA
BWI76_RS11725		+1.4	2.4	PTS sugar transporter subunit IIB
BWI76_RS13970		+1.4	3.3	ABC transporter
BWI76_RS21000		+1.4	2.1	exopolyphosphatase
BWI76_RS19440		+1.4	1.0	putative transporter subunit
BWI76_RS04360		+1.4	1.5	ribonucleoside hydrolase RihC
BWI76_RS16490		+1.4	3.2	glutaredoxin
BWI76_RS19585		+1.4	1.6	gentisate 1,2-dioxygenase
BWI76_RS27450		+1.3	2.1	ferredoxin--NADP(+) reductase
BWI76_RS19380		+1.3	0.9	hydroxyethylthiazole kinase
BWI76_RS16480		+1.3	1.3	lactoylglutathione lyase
BWI76_RS14045		+1.3	5.5	oxidoreductase
BWI76_RS09065		+1.3	1.3	sugar phosphatase SupH
BWI76_RS25160		+1.3	2.4	transcription elongation factor GreA
BWI76_RS16230		+1.3	1.0	dihydromonapterin reductase
BWI76_RS08620		+1.3	0.9	galactose-1-phosphate uridylyltransferase
BWI76_RS10485		+1.3	1.0	(hypo)xanthine hydroxylase reductase
BWI76_RS20025		+1.3	1.4	HAMP domain-containing histidine kinase
BWI76_RS04425		+1.3	3.5	oxaloacetate decarboxylase subunit gamma
BWI76_RS13680		+1.3	1.0	methyl viologen resistance protein SmvA
BWI76_RS02440		+1.3	2.2	fumarate reductase subunit D
BWI76_RS08910		+1.3	1.9	transketolase domain-containing protein
BWI76_RS11840		+1.3	1.4	tryptophan synthase subunit alpha
BWI76_RS10500		+1.2	1.2	flavoprotein monooxygenase
BWI76_RS06900		+1.2	1.9	phospholipase D
BWI76_RS06540		+1.2	3.5	DNA-binding protein HU-beta
BWI76_RS17290		+1.2	2.2	formyltetrahydrofolate deformylase
BWI76_RS02795		+1.2	2.0	periplasmic binding protein/LacI transcriptional regulator
BWI76_RS10285		+1.2	1.7	family 3 extracellular solute-binding protein
BWI76_RS04155		+1.2	1.3	membrane protein
BWI76_RS25295		+1.2	1.5	glutamine amidotransferase
BWI76_RS07840		+1.2	1.2	inositol monophosphatase family protein
BWI76_RS27425		+1.2	1.5	DNA-directed RNA polymerase subunit omega
BWI76_RS15665		+1.1	1.1	hypothetical protein
BWI76_RS26960		+1.1	1.7	bifunctional glyoxylate/hydroxypyruvate reductase B
BWI76_RS02180		+1.1	1.2	hypothetical protein
BWI76_RS09280		+1.1	1.3	terminase endonuclease subunit
BWI76_RS04645		+1.1	0.9	3-dehydroquinase
BWI76_RS09025		+1.1	1.8	GntR family transcriptional regulator
BWI76_RS26805		+1.1	1.8	cellulose biosynthesis protein BcsF
BWI76_RS07820		+1.1	0.9	S-methyl-5-thioribose kinase
BWI76_RS02510		+1.1	2.3	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase
BWI76_RS18270		+1.1	2.4	hypothetical protein
BWI76_RS05480		+1.0	1.1	class II glutamine amidotransferase
BWI76_RS14655		+1.0	2.6	FKBP-type peptidyl-prolyl isomerase domain-containing protein
BWI76_RS18725		+1.0	1.0	hypothetical protein
BWI76_RS15790		+1.0	1.9	replication protein
BWI76_RS18440		+1.0	1.7	GtrA-like protein
BWI76_RS18605		+1.0	1.5	oxidoreductase molybdopterin-binding protein
BWI76_RS12545		+1.0	2.3	hypothetical protein
BWI76_RS24260		+1.0	2.7	hypothetical protein
BWI76_RS16515		+1.0	2.0	LysR family transcriptional regulator
BWI76_RS15735		+1.0	2.4	hypothetical protein
BWI76_RS07805		+1.0	1.8	sugar ABC transporter permease
BWI76_RS05795		+1.0	1.5	hypothetical protein
BWI76_RS14465		+1.0	1.6	transcriptional regulator
BWI76_RS18345		+1.0	2.8	transcriptional regulator SdiA
BWI76_RS10745		+1.0	1.1	hypothetical protein
BWI76_RS23845		+1.0	1.2	ASCH domain-containing protein
BWI76_RS11195		+1.0	2.9	multiple stress resistance protein BhsA
BWI76_RS12390		+1.0	0.7	antibiotic biosynthesis monooxygenase
BWI76_RS24600		+0.9	1.6	dihydroxyacetone kinase
BWI76_RS15950		+0.9	1.9	dethiobiotin synthase
BWI76_RS20795		+0.9	0.9	ethanolamine catabolic microcompartment shell protein EutN
BWI76_RS20380		+0.9	0.8	tRNA pseudouridine(38-40) synthase TruA
BWI76_RS18565		+0.9	1.6	pemk protein
BWI76_RS00480		+0.9	1.3	hypothetical protein
BWI76_RS00590		+0.9	3.2	hypothetical protein
BWI76_RS09820		+0.9	1.8	hypothetical protein
BWI76_RS13030		+0.9	2.3	site-specific recombinase, phage integrase family protein
BWI76_RS14680		+0.9	2.1	SefF
BWI76_RS04995		+0.9	2.6	3-methyl-2-oxobutanoate hydroxymethyltransferase
BWI76_RS26660		+0.9	1.8	transcription elongation factor GreB
BWI76_RS12145		+0.9	0.7	hypothetical protein
BWI76_RS24540		+0.9	1.1	hypothetical protein
BWI76_RS22230		+0.9	1.3	Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data)
BWI76_RS20850		+0.9	1.5	oxidoreductase FeS-binding subunit
BWI76_RS22280		+0.9	1.1	formate dehydrogenase-H ferredoxin subunit
BWI76_RS05555		+0.9	1.4	Crl family RNA polymerase assembly factor
BWI76_RS26875		+0.9	2.2	dipeptide ABC transporter permease DppC
BWI76_RS23315		+0.9	2.1	acyl-[ACP]--phospholipid O-acyltransferase
BWI76_RS26130		+0.9	3.7	ADP compounds hydrolase NudE
BWI76_RS08595		+0.9	1.4	hypothetical protein
BWI76_RS24110		+0.9	1.9	YggU family protein
BWI76_RS07760		+0.9	2.5	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
BWI76_RS07710		+0.9	1.0	invasin-like protein
BWI76_RS15010		+0.9	1.5	hypothetical protein
BWI76_RS10710		+0.9	1.1	Glutamate--putrescine ligase (EC 6.3.1.11) (from data)
BWI76_RS13785		+0.9	1.5	ABC transporter permease
BWI76_RS11060		+0.9	1.7	septum formation inhibitor Maf
BWI76_RS11815		+0.9	1.3	hypothetical protein
BWI76_RS14065		+0.9	0.8	hypothetical protein
BWI76_RS22335		+0.9	0.8	4Fe-4S ferredoxin
BWI76_RS14730		+0.9	1.1	4-oxalocrotonate tautomerase
BWI76_RS14475		+0.9	2.0	serine/threonine transporter
BWI76_RS00940		+0.9	3.3	transcriptional regulator HdfR
BWI76_RS24955		+0.9	1.6	hypothetical protein
BWI76_RS07985		+0.9	0.8	fluoride ion transporter CrcB
BWI76_RS05570		+0.9	0.8	hypothetical protein
BWI76_RS07255		+0.8	1.3	hypothetical protein
BWI76_RS12470		+0.8	1.2	thiosulfate sulfurtransferase PspE
BWI76_RS11920		+0.8	2.0	hypothetical protein
BWI76_RS10770		+0.8	1.5	pyrimidine utilization protein C
BWI76_RS21740		+0.8	1.8	transcriptional regulator, LysR family protein
BWI76_RS21050		+0.8	1.0	hypothetical protein
BWI76_RS15700		+0.8	0.7	hypothetical protein
BWI76_RS13540		+0.8	0.9	ABC transporter substrate-binding protein
BWI76_RS07025		+0.8	2.0	glycerate kinase II
BWI76_RS13720		+0.8	1.4	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
BWI76_RS19850		+0.8	1.0	tRNA-Pro
BWI76_RS15130		+0.8	2.5	hypothetical protein
BWI76_RS18585		+0.8	1.6	two-component sensor histidine kinase
BWI76_RS27040		+0.8	1.7	xylose ABC transporter permease
BWI76_RS10400		+0.8	1.2	hypothetical protein
BWI76_RS12595		+0.8	1.4	hypothetical protein
BWI76_RS14095		+0.8	1.3	hypothetical protein
BWI76_RS05440		+0.8	1.3	hydroxyacylglutathione hydrolase
BWI76_RS01240		+0.8	1.7	phospholipase A
BWI76_RS12665		+0.8	1.2	hypothetical protein
BWI76_RS05685		+0.8	2.9	dihydrodipicolinate synthase family protein
BWI76_RS13055		+0.8	0.9	NmrA family protein
BWI76_RS17555		+0.8	2.0	permease
BWI76_RS18595		+0.8	3.6	hypothetical protein
BWI76_RS16450		+0.8	1.2	fusaric acid resistance protein
BWI76_RS16680		+0.8	1.1	ABC transporter substrate-binding protein
BWI76_RS00985		+0.8	1.3	transcriptional regulator IlvY
BWI76_RS22645		+0.8	3.3	RNA polymerase sigma factor RpoS
BWI76_RS01560		+0.8	3.6	Rsd/AlgQ family anti-sigma factor
BWI76_RS26930		+0.8	1.3	biotin sulfoxide reductase
BWI76_RS26440		+0.8	1.0	hypothetical protein
BWI76_RS01585		+0.8	2.8	transcriptional regulator
BWI76_RS00400		+0.8	0.4	glutamine synthetase
BWI76_RS08975		+0.8	1.8	amino acid ABC transporter substrate-binding protein
BWI76_RS03105		+0.8	0.8	myo-inosose-2 dehydratase
BWI76_RS25640		+0.8	0.9	hypothetical protein
BWI76_RS06370		+0.8	0.8	phosphatidylglycerophosphatase A
BWI76_RS22390		+0.8	2.1	maltoporin
BWI76_RS21905		+0.8	1.2	class II aldolase
BWI76_RS22520		+0.8	1.3	3-oxoacyl-ACP synthase
BWI76_RS10430		+0.8	2.2	thiol:disulfide interchange protein DsbG
BWI76_RS23510		+0.8	1.2	transcriptional regulator
BWI76_RS26935		+0.8	1.1	OmpA family lipoprotein
BWI76_RS06975		+0.8	0.9	DNA-binding transcriptional activator AllS
BWI76_RS00575		+0.8	1.1	DNA-binding protein

Specific Phenotypes

For 8 genes in this experiment