Experiment set32IT046 for Klebsiella michiganensis M5al

200 most detrimental genes:

gene	name	fitness	t score	description
BWI76_RS01885		+6.7	16.3	CsbD family protein
BWI76_RS06540		+5.6	2.6	DNA-binding protein HU-beta
BWI76_RS21070		+5.0	2.7	outer membrane protein assembly factor BamB
BWI76_RS06595		+4.6	16.2	hypothetical protein
BWI76_RS06530		+4.4	12.2	ATP-dependent Clp protease ATP-binding subunit ClpX
BWI76_RS23285		+4.3	19.2	hypothetical protein
BWI76_RS06525		+4.1	23.2	ATP-dependent Clp protease proteolytic subunit
BWI76_RS18800		+3.8	17.7	transcriptional regulator
BWI76_RS16290		+2.9	1.2	Mal regulon transcriptional regulator MalI
BWI76_RS18060		+2.9	1.8	hypothetical protein
BWI76_RS17765		+2.9	1.5	hypothetical protein
BWI76_RS16025		+2.7	2.0	triphosphoribosyl-dephospho-CoA synthase
BWI76_RS12095		+2.6	2.0	hypothetical protein
BWI76_RS25195		+2.5	1.4	maltose metabolism regulator
BWI76_RS03815		+2.5	1.6	hypothetical protein
BWI76_RS19700		+2.4	1.6	deoxyribonuclease IV
BWI76_RS05050		+2.3	1.8	general secretion pathway protein GspL
BWI76_RS12080		+2.2	1.6	hypothetical protein
BWI76_RS02930		+2.2	1.5	anaerobic ribonucleoside-triphosphate reductase activating protein
BWI76_RS09130		+2.2	1.3	biofilm formation regulatory protein BssR
BWI76_RS25060		+2.1	6.1	lipoprotein NlpI
BWI76_RS14090		+2.1	1.7	polyketide cyclase
BWI76_RS13975		+2.1	1.6	urea carboxylase
BWI76_RS10920		+2.0	1.2	putative TetR family transcriptional regulator
BWI76_RS18905		+2.0	3.5	putrescine/spermidine ABC transporter
BWI76_RS10470		+1.9	1.1	iron ABC transporter substrate-binding protein
BWI76_RS05895		+1.8	0.9	phosphonate ABC transporter, permease protein PhnE
BWI76_RS21920		+1.8	1.2	amino acid ABC transporter substrate-binding protein
BWI76_RS25970		+1.7	1.5	hypothetical protein
BWI76_RS22620		+1.7	1.5	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
BWI76_RS12145		+1.7	1.3	hypothetical protein
BWI76_RS13325		+1.7	1.3	dicarboxylate transporter/tellurite-resistance protein TehA
BWI76_RS13890		+1.6	1.4	LysR family transcriptional regulator
BWI76_RS01585		+1.6	1.9	transcriptional regulator
BWI76_RS25870		+1.6	2.3	elongation factor Tu
BWI76_RS13755		+1.6	3.1	hypothetical protein
BWI76_RS19540		+1.6	2.0	multidrug transporter permease
BWI76_RS15775		+1.6	3.6	replication protein
BWI76_RS17975		+1.6	3.9	tail-specific protease
BWI76_RS24955		+1.6	1.9	hypothetical protein
BWI76_RS13970		+1.6	3.2	ABC transporter
BWI76_RS11040		+1.6	0.8	ribonuclease E
BWI76_RS10710		+1.6	1.5	Glutamate--putrescine ligase (EC 6.3.1.11) (from data)
BWI76_RS15290		+1.5	2.1	transcriptional regulator
BWI76_RS25335		+1.5	2.0	stringent starvation protein A
BWI76_RS11365		+1.5	1.4	iron ABC transporter
BWI76_RS01775		+1.5	1.8	hypothetical protein
BWI76_RS12485		+1.5	1.2	TyrR family transcriptional regulator
BWI76_RS00370		+1.5	1.5	GTPase-activating protein
BWI76_RS06695		+1.5	1.9	ABC transporter substrate-binding protein
BWI76_RS05810		+1.5	1.7	hypothetical protein
BWI76_RS13250		+1.4	1.9	cytochrome b561
BWI76_RS21165		+1.4	2.3	Fe-S cluster assembly transcriptional regulator IscR
BWI76_RS24650		+1.4	1.5	putative transport system permease component
BWI76_RS11250		+1.4	1.1	spermidine/putrescine ABC transporter permease PotB
BWI76_RS00060		+1.4	3.6	N-acetylneuraminate lyase
BWI76_RS12745		+1.4	2.9	putative prophage membrane protein
BWI76_RS20925		+1.4	2.9	peptidase M48
BWI76_RS20230		+1.4	1.2	hypothetical protein
BWI76_RS12570		+1.4	1.8	DUF1365 domain-containing protein
BWI76_RS22860		+1.4	5.1	SecY-interacting protein
BWI76_RS02880		+1.4	1.8	membrane protein
BWI76_RS25850		+1.3	1.4	prepilin peptidase
BWI76_RS22215		+1.3	0.9	PTS sorbitol transporter subunit IIC
BWI76_RS17180		+1.3	1.3	hypothetical protein
BWI76_RS03540		+1.3	4.6	tryptophanase leader peptide
BWI76_RS25065		+1.3	2.2	polyribonucleotide nucleotidyltransferase
BWI76_RS13980		+1.3	2.1	hypothetical protein
BWI76_RS18930		+1.3	1.2	histidinol-phosphate transaminase
BWI76_RS16490		+1.3	2.3	glutaredoxin
BWI76_RS12790		+1.2	1.4	lactate dehydrogenase
BWI76_RS15335		+1.2	1.2	branched-chain amino acid ABC transporter permease
BWI76_RS08840		+1.2	2.6	hypothetical protein
BWI76_RS17880		+1.2	0.9	c-di-GMP phosphodiesterase
BWI76_RS02885		+1.2	1.4	dihydroorotase
BWI76_RS02440		+1.2	1.6	fumarate reductase subunit D
BWI76_RS19365		+1.2	3.0	ribulokinase
BWI76_RS19750		+1.2	2.3	elongation factor P-like protein YeiP
BWI76_RS24680		+1.2	2.0	23S rRNA (guanine(1835)-N(2))-methyltransferase
BWI76_RS27605		+1.2	1.8	hypothetical protein
BWI76_RS20475		+1.2	1.9	phospholipid-binding lipoprotein MlaA
BWI76_RS00940		+1.2	1.6	transcriptional regulator HdfR
BWI76_RS01565		+1.2	1.7	NADH pyrophosphatase
BWI76_RS11815		+1.1	1.6	hypothetical protein
BWI76_RS13095		+1.1	1.8	phenylacetate-CoA oxygenase subunit PaaB
BWI76_RS17860		+1.1	1.9	YoaH family protein
BWI76_RS12575		+1.1	1.9	FAD-dependent oxidoreductase
BWI76_RS16525		+1.1	1.3	cyclopropane-fatty-acyl-phospholipid synthase
BWI76_RS24215		+1.1	1.4	LysR family transcriptional regulator
BWI76_RS06640		+1.1	1.6	hypothetical protein
BWI76_RS19570		+1.1	1.5	3-hydroxybenzoate 6-hydroxylase
BWI76_RS23375		+1.1	1.1	cupin
BWI76_RS19355		+1.1	5.1	LacI family transcriptional regulator
BWI76_RS01560		+1.1	4.1	Rsd/AlgQ family anti-sigma factor
BWI76_RS22645		+1.1	2.9	RNA polymerase sigma factor RpoS
BWI76_RS24580		+1.1	1.3	PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR
BWI76_RS12440		+1.1	1.8	MFS transporter
BWI76_RS23315		+1.1	2.0	acyl-[ACP]--phospholipid O-acyltransferase
BWI76_RS08455		+1.1	2.4	glutaminase
BWI76_RS14435		+1.1	1.7	glutamine ABC transporter ATP-binding protein
BWI76_RS15000		+1.1	1.5	amino acid ABC transporter ATP-binding protein
BWI76_RS05655		+1.1	1.5	hypothetical protein
BWI76_RS24055		+1.1	1.4	MFS transporter
BWI76_RS16830		+1.1	1.9	ABC transporter
BWI76_RS06895		+1.1	1.7	biopolymer transporter ExbB
BWI76_RS09195		+1.1	1.5	N-acetyltransferase
BWI76_RS13685		+1.1	1.6	IclR family transcriptional regulator
BWI76_RS04895		+1.1	0.9	hypothetical protein
BWI76_RS16660		+1.1	1.8	SfnB family sulfur acquisition oxidoreductase
BWI76_RS23320		+1.1	1.4	hypothetical protein
BWI76_RS16275		+1.1	1.3	fumarate hydratase FumA
BWI76_RS15680		+1.1	1.2	hypothetical protein
BWI76_RS18770		+1.1	0.9	DNA gyrase inhibitor
BWI76_RS20285		+1.0	2.0	glutathione S-transferase
BWI76_RS16335		+1.0	1.5	division septum protein Blr
BWI76_RS18605		+1.0	1.0	oxidoreductase molybdopterin-binding protein
BWI76_RS21075		+1.0	0.7	membrane protein
BWI76_RS26565		+1.0	1.4	membrane protein
BWI76_RS27510		+1.0	1.4	aquaporin
BWI76_RS04655		+1.0	1.3	shikimate dehydrogenase
BWI76_RS19400		+1.0	1.5	NCS2 family permease
BWI76_RS24950		+1.0	2.7	hypothetical protein
BWI76_RS04450		+1.0	1.1	citrate lyase subunit alpha
BWI76_RS21505		+1.0	1.1	hypothetical protein
BWI76_RS04835		+1.0	1.3	type II secretion system protein GspE
BWI76_RS15300		+1.0	1.0	multiple antibiotic resistance regulatory periplasmic protein MarB
BWI76_RS15990		+1.0	0.9	serine protease
BWI76_RS23905		+1.0	0.8	Z-ring-associated protein
BWI76_RS08255		+1.0	1.0	tricarballylate dehydrogenase
BWI76_RS26580		+1.0	1.5	universal stress protein A
BWI76_RS24070		+1.0	1.6	16S rRNA (uracil(1498)-N(3))-methyltransferase
BWI76_RS16930		+1.0	2.0	transcriptional regulator
BWI76_RS04090		+1.0	1.0	ribosomal-protein-alanine N-acetyltransferase RimI
BWI76_RS16220		+1.0	1.7	hypothetical protein
BWI76_RS09480		+1.0	1.2	hypothetical protein
BWI76_RS19910		+1.0	2.4	phosphotransferase RcsD
BWI76_RS12420		+1.0	1.0	peptide ABC transporter substrate-binding protein SapA
BWI76_RS27425		+1.0	0.9	DNA-directed RNA polymerase subunit omega
BWI76_RS04970		+1.0	1.0	ABC transporter permease
BWI76_RS22640		+1.0	2.1	hypothetical protein
BWI76_RS11610		+1.0	1.1	glutamate dehydrogenase
BWI76_RS02745		+1.0	1.1	hypothetical protein
BWI76_RS02595		+1.0	3.5	hypothetical protein
BWI76_RS09790		+1.0	1.9	ComEC family protein
BWI76_RS21800		+1.0	2.3	MASE2 domain/diguanylate cyclase
BWI76_RS10060		+1.0	1.1	acylphosphatase
BWI76_RS22810		+1.0	1.4	23S rRNA (uracil(1939)-C(5))-methyltransferase
BWI76_RS10290		+1.0	2.5	transcriptional regulator
BWI76_RS15470		+1.0	1.4	dipeptidyl carboxypeptidase II
BWI76_RS06195		+1.0	1.2	hypothetical protein
BWI76_RS05025		+1.0	2.1	2'-5' RNA ligase
BWI76_RS13810		+1.0	1.4	MarR family transcriptional regulator
BWI76_RS19980		+0.9	1.6	2-keto-3-deoxy-L-rhamnonate aldolase
BWI76_RS24305		+0.9	2.7	2,5-didehydrogluconate reductase A
BWI76_RS09940		+0.9	1.0	paraquat-inducible protein B
BWI76_RS01260		+0.9	1.3	lysophospholipase L2
BWI76_RS19105		+0.9	1.8	GalU regulator GalF
BWI76_RS03095		+0.9	1.3	Inositol 2-dehydrogenase (EC 1.1.1.18) (from data)
BWI76_RS18385		+0.9	0.8	hypothetical protein
BWI76_RS26850		+0.9	2.2	cellulose synthase catalytic subunit (UDP-forming)
BWI76_RS13155		+0.9	1.1	hypothetical protein
BWI76_RS15195		+0.9	0.9	DUF4186 domain-containing protein
BWI76_RS12670		+0.9	1.7	DNA polymerase V subunit UmuD
BWI76_RS19240		+0.9	1.2	ABC transporter substrate-binding protein
BWI76_RS05685		+0.9	1.8	dihydrodipicolinate synthase family protein
BWI76_RS17785		+0.9	1.3	septum site-determining protein MinD
BWI76_RS07940		+0.9	1.0	alkyl hydroperoxide reductase subunit C
BWI76_RS20490		+0.9	1.4	hypothetical protein
BWI76_RS04560		+0.9	1.8	holo-ACP synthase CitX
BWI76_RS14055		+0.9	1.5	LacI family transcriptional regulator
BWI76_RS17320		+0.9	0.9	respiratory nitrate reductase subunit gamma
BWI76_RS09650		+0.9	1.4	hypothetical protein
BWI76_RS14065		+0.9	0.5	hypothetical protein
BWI76_RS09885		+0.9	1.9	nicotinate phosphoribosyltransferase
BWI76_RS27560		+0.9	1.2	hypothetical protein
BWI76_RS14760		+0.9	1.2	PTS ascorbate transporter subunit IIC
BWI76_RS19755		+0.9	1.1	fructuronate reductase
BWI76_RS16195		+0.9	1.1	hypothetical protein
BWI76_RS17750		+0.9	1.0	Na+/H+ antiporter NhaB
BWI76_RS26525		+0.9	1.4	nickel-responsive transcriptional regulator NikR
BWI76_RS16485		+0.9	0.8	ribonuclease T
BWI76_RS08885		+0.9	1.5	transcriptional regulator
BWI76_RS14110		+0.9	0.7	C-lysozyme inhibitor
BWI76_RS23310		+0.9	1.0	lysophospholipid transporter LplT
BWI76_RS24625		+0.9	1.6	hypothetical protein
BWI76_RS19525		+0.9	2.1	D-alanyl-D-alanine endopeptidase
BWI76_RS27950		+0.9	1.7	transcriptional regulator
BWI76_RS22205		+0.9	0.9	cation ABC transporter ATP-binding protein
BWI76_RS12855		+0.9	0.8	enamine deaminase RidA
BWI76_RS07515		+0.9	1.8	glutamate--cysteine ligase
BWI76_RS21740		+0.9	1.3	transcriptional regulator, LysR family protein
BWI76_RS20045		+0.9	1.0	hypothetical protein
BWI76_RS02180		+0.9	0.8	hypothetical protein
BWI76_RS06135		+0.9	2.8	MFS transporter
BWI76_RS00665		+0.9	1.7	rhamnose ABC transporter substrate-binding protein
BWI76_RS14915		+0.9	1.4	hypothetical protein
BWI76_RS09100		+0.9	1.2	glutathione ABC transporter substrate-binding protein GsiB
BWI76_RS11735		+0.9	0.9	PTS N,N'-diacetylchitobiose transporter subunit IIA
BWI76_RS11890		+0.9	1.3	glycosyl hydrolase
BWI76_RS17570		+0.9	1.7	iron-sulfur-binding protein

Specific Phenotypes

For 2 genes in this experiment