Experiment set2IT093 for Methanococcus maripaludis JJ

200 most detrimental genes:

gene	name	fitness	t score	description
MMJJ_RS04215		+3.7	23.4	DMT family transporter
MMJJ_RS06940		+3.5	11.3	metalloregulator ArsR/SmtB family transcription factor
MMJJ_RS03205		+3.0	10.8	metallophosphoesterase
MMJJ_RS05675		+2.6	18.9	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMJJ_RS06820		+2.6	5.1	CBS domain-containing protein
MMJJ_RS07030		+2.3	14.4	hypothetical protein
MMJJ_RS03140		+2.3	9.1	tRNA-dihydrouridine synthase
MMJJ_RS05680		+2.1	10.8	hypothetical protein
MMJJ_RS01785		+2.0	2.0	50S ribosomal protein L14e
MMJJ_RS01980		+2.0	11.0	cation:proton antiporter
MMJJ_RS03830		+1.9	7.6	CBS domain-containing protein
MMJJ_RS08260		+1.9	11.3	ABC transporter ATP-binding protein
MMJJ_RS06945		+1.9	5.9	molybdopterin-guanine dinucleotide biosynthesis protein MobB
MMJJ_RS08265		+1.8	11.7	iron ABC transporter permease
MMJJ_RS08715		+1.8	4.6	NAD-dependent epimerase/dehydratase family protein
MMJJ_RS06975		+1.8	2.7	protein translocase SEC61 complex subunit gamma
MMJJ_RS00040		+1.8	4.6	CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon
MMJJ_RS07280		+1.7	5.5	phosphomannomutase/phosphoglucomutase
MMJJ_RS07235		+1.7	11.5	coenzyme F420 hydrogenase subunit alpha
MMJJ_RS00060		+1.7	9.7	acetyl-CoA decarbonylase/synthase complex subunit gamma
MMJJ_RS03135		+1.6	6.0	CBS domain-containing protein
MMJJ_RS07225		+1.6	8.3	coenzyme F420 hydrogenase subunit gamma
MMJJ_RS00055		+1.6	6.4	CO dehydrogenase/acetyl-CoA synthase subunit delta
MMJJ_RS05870		+1.5	2.5	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMJJ_RS00070		+1.5	4.5	CooT family nickel-binding protein
MMJJ_RS06810		+1.5	9.5	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
MMJJ_RS05010		+1.5	9.9	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
MMJJ_RS06055		+1.5	8.3	S-methyl-5-thioribose-1-phosphate isomerase
MMJJ_RS08480		+1.4	5.2	hydroxyethylthiazole kinase
MMJJ_RS07230		+1.4	6.6	coenzyme F420-reducing hydrogenase, FrhD protein
MMJJ_RS07220		+1.4	9.8	coenzyme F420 hydrogenase subunit beta
MMJJ_RS05510		+1.4	6.9	archaellum operon transcriptional activator EarA family protein
MMJJ_RS00045		+1.4	7.6	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMJJ_RS00050		+1.3	6.8	AAA family ATPase
MMJJ_RS08270		+1.3	9.1	iron ABC transporter substrate-binding protein
MMJJ_RS00035		+1.3	8.4	CO dehydrogenase/acetyl-CoA synthase complex subunit alpha
MMJJ_RS06090		+1.3	4.0	hypothetical protein
MMJJ_RS05915		+1.3	2.2	multiprotein bridging factor aMBF1
MMJJ_RS06675		+1.2	5.6	TIGR01212 family radical SAM protein
MMJJ_RS05505		+1.2	10.6	hypothetical protein
MMJJ_RS00080		+1.2	5.9	DUF166 domain-containing protein
MMJJ_RS08750		+1.2	4.7	glycosyltransferase
MMJJ_RS07650		+1.2	6.8	formate/nitrite transporter family protein
MMJJ_RS08065		+1.2	1.3	precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT
MMJJ_RS00065		+1.1	6.3	4Fe-4S dicluster domain-containing protein
MMJJ_RS06540		+1.1	2.4	DUF2120 domain-containing protein
MMJJ_RS05820		+1.1	3.0	DUF2304 domain-containing protein
MMJJ_RS06755		+1.1	5.5	diadenylate cyclase
MMJJ_RS04480		+1.1	1.7	hypothetical protein
MMJJ_RS01010		+1.1	9.2	right-handed parallel beta-helix repeat-containing protein
MMJJ_RS08935		+1.1	0.8	TIGR00288 family NYN domain-containing protein
MMJJ_RS07635		+1.1	4.8	response regulator transcription factor
MMJJ_RS06830		+1.1	3.7	4Fe-4S binding protein
MMJJ_RS06740		+1.0	3.1	energy-coupling factor ABC transporter substrate-binding protein
MMJJ_RS07380		+1.0	3.7	sulfide-dependent adenosine diphosphate thiazole synthase
MMJJ_RS07680		+1.0	3.0	glucose-6-phosphate isomerase
MMJJ_RS00415		+1.0	1.9	DedA family protein
MMJJ_RS04720		+1.0	0.9	IMP dehydrogenase
MMJJ_RS01375		+1.0	4.9	tetrahydromethanopterin:alpha-L-glutamate ligase
MMJJ_RS02080		+1.0	5.7	AMP-binding protein
MMJJ_RS08730		+1.0	4.3	glycosyltransferase family 4 protein
MMJJ_RS08780		+1.0	3.0	D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
MMJJ_RS01825		+1.0	2.2	DNA repair and recombination protein RadB
MMJJ_RS04500		+1.0	5.0	hypothetical protein
MMJJ_RS01125		+0.9	2.2	hypothetical protein
MMJJ_RS08550		+0.9	4.6	B12-binding domain-containing radical SAM protein
MMJJ_RS07935		+0.9	0.9	protein fwdD
MMJJ_RS03850		+0.9	3.1	nucleoside-diphosphate kinase
MMJJ_RS04005		+0.9	4.5	acetate--CoA ligase family protein
MMJJ_RS06280		+0.9	5.1	hypothetical protein
MMJJ_RS01920		+0.9	5.3	phosphoglycerate mutase
MMJJ_RS03175		+0.9	3.7	zinc metalloprotease HtpX
MMJJ_RS08175		+0.9	4.2	winged helix-turn-helix transcriptional regulator
MMJJ_RS05790		+0.9	4.7	flagellin
MMJJ_RS05800		+0.9	4.1	coenzyme F420-0:L-glutamate ligase
MMJJ_RS02180		+0.9	3.2	DHH family phosphoesterase
MMJJ_RS08710		+0.9	2.0	UTP--glucose-1-phosphate uridylyltransferase GalU
MMJJ_RS01850		+0.9	3.0	RNA 2',3'-cyclic phosphodiesterase
MMJJ_RS07185		+0.9	1.1	DUF371 domain-containing protein
MMJJ_RS08630		+0.8	2.9	signal recognition particle subunit SRP19/SEC65 family protein
MMJJ_RS00940		+0.8	4.4	aldo/keto reductase
MMJJ_RS02935		+0.8	1.3	DNA-directed RNA polymerase subunit E''
MMJJ_RS08765		+0.8	3.6	glycosyltransferase family 9 protein
MMJJ_RS06470		+0.8	3.8	tripartite tricarboxylate transporter permease
MMJJ_RS08760		+0.8	2.8	glycosyltransferase family 9 protein
MMJJ_RS06575		+0.8	0.9	prephenate dehydrogenase
MMJJ_RS06710		+0.8	5.1	TldD/PmbA family protein
MMJJ_RS07660		+0.8	2.5	carbonic anhydrase
MMJJ_RS02085		+0.7	3.9	hypothetical protein
MMJJ_RS01465		+0.7	2.3	METTL5 family protein
MMJJ_RS02850		+0.7	1.4	hypothetical protein
MMJJ_RS05115		+0.7	1.4	P-II family nitrogen regulator
MMJJ_RS08775		+0.7	2.9	PfkB family carbohydrate kinase
MMJJ_RS06640		+0.7	2.9	YfcE family phosphodiesterase
MMJJ_RS04780		+0.7	0.8	nucleic acid-binding protein
MMJJ_RS03730		+0.7	1.3	SWIM zinc finger family protein
MMJJ_RS05190		+0.7	2.4	gamma carbonic anhydrase family protein
MMJJ_RS08225		+0.6	1.5	peptidylprolyl isomerase
MMJJ_RS01380		+0.6	2.4	DUF1890 domain-containing protein
MMJJ_RS06460		+0.6	2.7	cytochrome c
MMJJ_RS06205		+0.6	3.1	EamA family transporter
MMJJ_RS07620		+0.6	3.0	class I SAM-dependent rRNA methyltransferase
MMJJ_RS01745		+0.6	2.1	metal-dependent transcriptional regulator
MMJJ_RS00300		+0.6	2.8	chemotaxis protein CheC
MMJJ_RS04230		+0.6	3.9	ABC transporter ATP-binding protein
MMJJ_RS03505		+0.6	3.6	trimeric intracellular cation channel family protein
MMJJ_RS06585		+0.6	2.6	alanine racemase
MMJJ_RS06115		+0.6	2.7	pyruvate kinase
MMJJ_RS04930		+0.6	3.1	MFS transporter
MMJJ_RS09120		+0.6	0.7	aspartate kinase
MMJJ_RS02070		+0.6	3.9	XRE family transcriptional regulator
MMJJ_RS01395		+0.6	1.5	DUF1894 domain-containing protein
MMJJ_RS04635		+0.6	1.2	DUF367 family protein
MMJJ_RS07670		+0.6	3.2	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
MMJJ_RS06580		+0.6	2.8	alanine dehydrogenase
MMJJ_RS06825		+0.6	2.5	4Fe-4S binding protein
MMJJ_RS06720		+0.6	2.4	mechanosensitive ion channel family protein
MMJJ_RS07365		+0.6	2.7	CatB-related O-acetyltransferase
MMJJ_RS05885		+0.6	3.7	tungstate ABC transporter substrate-binding protein WtpA
MMJJ_RS06190		+0.6	2.9	7-cyano-7-deazaguanine synthase
MMJJ_RS03735		+0.6	3.2	2-oxoacid:acceptor oxidoreductase subunit alpha
MMJJ_RS06905		+0.6	0.5	hypothetical protein
MMJJ_RS00500		+0.6	2.2	GNAT family N-acetyltransferase
MMJJ_RS06550		+0.6	3.0	ABC transporter permease
MMJJ_RS06735		+0.6	2.4	cobalt ECF transporter T component CbiQ
MMJJ_RS04240		+0.6	3.5	molybdate ABC transporter substrate-binding protein
MMJJ_RS03485		+0.6	3.0	radical SAM protein
MMJJ_RS08525		+0.5	1.9	peptidylprolyl isomerase
MMJJ_RS06770		+0.5	3.1	hypothetical protein
MMJJ_RS04360		+0.5	1.3	winged helix-turn-helix transcriptional regulator
MMJJ_RS00675		+0.5	2.9	nitrogenase
MMJJ_RS00465		+0.5	2.4	selenouridine synthase SelU-like subunit
MMJJ_RS08295		+0.5	2.8	iron ABC transporter substrate-binding protein
MMJJ_RS04305		+0.5	4.3	right-handed parallel beta-helix repeat-containing protein
MMJJ_RS05990		+0.5	2.0	phosphatase PAP2 family protein
MMJJ_RS08755		+0.5	3.1	ADP-glyceromanno-heptose 6-epimerase
MMJJ_RS09325		+0.5	1.6	hypothetical protein
MMJJ_RS06925		+0.5	0.7	GMP synthase subunit A
MMJJ_RS07385		+0.5	2.5	ribosomal protein S18-alanine N-acetyltransferase
MMJJ_RS03250		+0.5	0.5	DUF2116 family Zn-ribbon domain-containing protein
MMJJ_RS04365		+0.5	1.8	helix-turn-helix transcriptional regulator
MMJJ_RS06465		+0.5	1.3	hypothetical protein
MMJJ_RS02265		+0.5	2.6	hypothetical protein
MMJJ_RS04510		+0.5	2.9	hypothetical protein
MMJJ_RS09155		+0.5	3.0	RluA family pseudouridine synthase
MMJJ_RS04825		+0.5	3.0	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
MMJJ_RS06455		+0.5	2.6	YeeE/YedE family protein
MMJJ_RS07390		+0.5	2.5	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMJJ_RS06210		+0.5	1.7	hypothetical protein
MMJJ_RS05605		+0.5	1.1	hypothetical protein
MMJJ_RS04545		+0.5	1.2	PadR family transcriptional regulator
MMJJ_RS03450		+0.5	1.5	hypothetical protein
MMJJ_RS03015		+0.5	2.2	Ig-like domain-containing protein
MMJJ_RS06745		+0.4	1.8	energy-coupling factor ABC transporter permease
MMJJ_RS04420		+0.4	2.4	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
MMJJ_RS07645		+0.4	1.5	selenium-binding protein
MMJJ_RS04115		+0.4	1.6	HDIG domain-containing protein
MMJJ_RS02005		+0.4	1.8	AzlC family ABC transporter permease
MMJJ_RS08930		+0.4	1.9	5'/3'-nucleotidase SurE
MMJJ_RS06285		+0.4	1.9	YchF/TatD family DNA exonuclease
MMJJ_RS03750		+0.4	1.8	rubredoxin
MMJJ_RS04415		+0.4	0.3	hypothetical protein
MMJJ_RS04535		+0.4	2.2	coenzyme gamma-F420-2:alpha-L-glutamate ligase
MMJJ_RS07260		+0.4	2.0	PspC domain-containing protein
MMJJ_RS07640		+0.4	3.0	cache domain-containing protein
MMJJ_RS00890		+0.4	2.2	coenzyme F420 hydrogenase subunit gamma
MMJJ_RS04725		+0.4	2.0	branched-chain-amino-acid transaminase
MMJJ_RS07425		+0.4	1.7	MBL fold metallo-hydrolase
MMJJ_RS02155		+0.4	1.8	DMT family transporter
MMJJ_RS02075		+0.4	0.7	acyl-CoA thioesterase
MMJJ_RS06555		+0.4	2.5	ATP-binding cassette domain-containing protein
MMJJ_RS01555		+0.4	2.2	Na/Pi cotransporter family protein
MMJJ_RS09095		+0.4	1.6	MMPL family transporter
MMJJ_RS08325		+0.4	0.4	glycosyltransferase family 2 protein
MMJJ_RS06440		+0.4	1.9	DUF4870 domain-containing protein
MMJJ_RS05580		+0.4	1.5	methanogenesis marker 9 domain-containing protein
MMJJ_RS04830		+0.4	1.3	zinc dependent phospholipase C family protein
MMJJ_RS05100		+0.4	1.3	P-II family nitrogen regulator
MMJJ_RS07215		+0.4	2.1	TIGR00341 family protein
MMJJ_RS00290		+0.4	1.9	CheF family chemotaxis protein
MMJJ_RS03625		+0.4	2.1	DUF63 family protein
MMJJ_RS05090		+0.4	1.0	MGMT family protein
MMJJ_RS05895		+0.4	2.2	ABC transporter permease
MMJJ_RS06365		+0.4	2.5	methyl coenzyme M reductase-arginine methyltransferase Mmp10
MMJJ_RS04530		+0.4	1.8	iron export ABC transporter permease subunit FetB
MMJJ_RS06960		+0.4	2.7	CAP domain-containing protein
MMJJ_RS06120		+0.4	1.8	DUF4013 domain-containing protein
MMJJ_RS06075		+0.4	1.8	DNA-binding protein Alba
MMJJ_RS06275		+0.4	1.1	hypothetical protein
MMJJ_RS07690		+0.4	1.6	glycosyltransferase family 4 protein
MMJJ_RS07655		+0.4	1.8	hypothetical protein
MMJJ_RS06520		+0.4	1.9	TldD/PmbA family protein
MMJJ_RS05435		+0.4	2.4	DUF2254 domain-containing protein
MMJJ_RS03510		+0.4	1.6	acyl-CoA dehydratase activase
MMJJ_RS03130		+0.4	1.4	DUF1611 domain-containing protein
MMJJ_RS07800		+0.4	2.1	AMP-binding protein
MMJJ_RS08235		+0.4	0.7	UPF0147 family protein
MMJJ_RS06445		+0.4	2.2	hypothetical protein
MMJJ_RS04405		+0.4	1.3	hypothetical protein
MMJJ_RS06045		+0.4	1.3	hypothetical protein

Specific Phenotypes

For 28 genes in this experiment