Experiment set2IT093 for Cupriavidus basilensis FW507-4G11

Compare to:

L-Tryptophan nitrogen source

200 most important genes:

  gene name fitness t score description  
RR42_RS16265 -8.2 -5.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
RR42_RS01385 -7.0 -4.8 5,10-methylenetetrahydrofolate reductase compare
RR42_RS16255 -6.7 -4.6 sulfate adenylyltransferase compare
RR42_RS05860 -6.5 -4.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
RR42_RS06485 -6.4 -4.4 chorismate synthase compare
RR42_RS14400 -6.2 -4.3 isopropylmalate isomerase compare
RR42_RS19005 -6.0 -4.1 3-dehydroquinate synthase compare
RR42_RS33255 -5.9 -3.7 protein-tyrosine phosphatase compare
RR42_RS16245 -5.8 -4.0 uroporphyrin-III methyltransferase compare
RR42_RS16250 -5.7 -6.8 sulfate adenylyltransferase compare
RR42_RS16275 -5.6 -3.9 membrane protein compare
RR42_RS11795 -5.5 -3.5 PEP synthetase regulatory protein compare
RR42_RS30655 -5.4 -6.4 LysR family transcriptional regulator compare
RR42_RS04475 -5.4 -8.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
RR42_RS14320 -5.1 -6.0 O-succinylhomoserine sulfhydrylase compare
RR42_RS14390 -5.0 -4.7 3-isopropylmalate dehydratase compare
RR42_RS15375 -5.0 -4.9 AsnC family transcriptional regulator conserved
RR42_RS16270 -5.0 -11.1 sulfite reductase compare
RR42_RS01160 -4.9 -9.5 homoserine O-acetyltransferase compare
RR42_RS15385 -4.9 -13.6 Kynureninase (EC 3.7.1.3) (from data) conserved
RR42_RS33240 -4.6 -15.6 GDP-L-fucose synthase compare
RR42_RS15890 -4.5 -9.1 heme biosynthesis protein HemY compare
RR42_RS33260 -4.5 -8.6 multidrug MFS transporter compare
RR42_RS14385 -4.5 -6.8 3-isopropylmalate dehydrogenase compare
RR42_RS15905 -4.4 -11.6 phosphoenolpyruvate carboxylase compare
RR42_RS12980 -4.3 -5.5 chemotaxis protein CheY compare
RR42_RS30660 -4.3 -7.7 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase compare
RR42_RS33250 -4.1 -7.4 tyrosine protein kinase compare
RR42_RS04535 -4.1 -6.2 cysteine synthase compare
RR42_RS12040 -4.0 -12.7 MFS transporter compare
RR42_RS19010 -4.0 -8.4 shikimate kinase compare
RR42_RS18990 -3.8 -16.9 glutamate synthase compare
RR42_RS16975 -3.8 -8.7 ABC transporter permease compare
RR42_RS16280 -3.6 -5.6 transcriptional regulator compare
RR42_RS15390 -3.5 -7.4 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (from data) conserved
RR42_RS13800 -3.4 -6.8 formyltetrahydrofolate deformylase compare
RR42_RS07555 -3.4 -3.4 potassium transporter Kup compare
RR42_RS33355 -3.4 -4.6 membrane protein compare
RR42_RS11790 -3.3 -7.3 phosphoenolpyruvate synthase compare
RR42_RS15740 -3.3 -3.8 hypothetical protein compare
RR42_RS17105 -3.3 -10.9 Clp protease ClpX compare
RR42_RS01845 -3.3 -2.0 glycerol-3-phosphate dehydrogenase compare
RR42_RS11885 -3.3 -9.7 (protein-PII) uridylyltransferase compare
RR42_RS33235 -3.3 -7.7 GDP-mannose 4,6-dehydratase compare
RR42_RS33210 -3.2 -6.6 teichoic acid biosynthesis protein compare
RR42_RS12985 -3.2 -7.4 histidine kinase compare
RR42_RS02705 -3.2 -3.0 Holliday junction DNA helicase RuvA compare
RR42_RS17645 -3.2 -5.3 shikimate dehydrogenase compare
RR42_RS15895 -3.2 -7.1 uroporphyrinogen III methyltransferase compare
RR42_RS13530 -3.1 -4.7 4-hydroxybenzoyl-CoA thioesterase compare
RR42_RS07605 -3.1 -7.4 poly-beta-hydroxybutyrate polymerase compare
RR42_RS18985 -3.1 -6.0 glutamate synthase compare
RR42_RS33245 -3.1 -7.9 mannose-1-phosphate guanyltransferase compare
RR42_RS18850 -3.1 -3.6 preprotein translocase subunit TatC compare
RR42_RS16260 -3.0 -2.6 phosphoadenosine phosphosulfate reductase compare
RR42_RS18855 -3.0 -4.5 preprotein translocase compare
RR42_RS16980 -3.0 -15.3 branched-chain amino acid ABC transporter substrate-binding protein compare
RR42_RS12550 -2.9 -4.6 hypothetical protein compare
RR42_RS16970 -2.9 -11.8 ABC transporter ATP-binding protein compare
RR42_RS16960 -2.8 -5.0 ABC transporter ATP-binding protein compare
RR42_RS21220 -2.8 -2.6 iron transporter FeoB compare
RR42_RS01775 -2.8 -5.4 glutamate--cysteine ligase compare
RR42_RS17720 -2.7 -3.4 sugar kinase compare
RR42_RS26900 -2.6 -3.8 enoyl-CoA hydratase compare
RR42_RS08945 -2.6 -2.1 hypothetical protein compare
RR42_RS16240 -2.6 -1.4 cobalamin biosynthesis protein CbiX compare
RR42_RS16965 -2.6 -3.5 ABC transporter compare
RR42_RS15380 -2.6 -2.8 kynurenine formamidase compare
RR42_RS03080 -2.5 -5.0 recombinase RecA compare
RR42_RS01290 -2.5 -4.7 thiamine biosynthesis protein ThiC compare
RR42_RS04460 -2.5 -4.4 chorismate mutase compare
RR42_RS24605 -2.3 -8.0 TetR family transcriptional regulator compare
RR42_RS03095 -2.3 -3.0 succinyl-CoA synthetase subunit beta compare
RR42_RS02085 -2.3 -7.0 RNA polymerase subunit sigma-54 compare
RR42_RS02210 -2.3 -1.9 succinate dehydrogenase compare
RR42_RS15400 -2.2 -7.0 acyl-CoA dehydrogenase compare
RR42_RS01780 -2.2 -7.4 glutathione synthetase compare
RR42_RS21755 -2.2 -1.4 shikimate dehydrogenase compare
RR42_RS20205 -2.1 -2.4 chromosome partitioning protein compare
RR42_RS13550 -2.1 -5.1 3-hydroxyacyl-CoA dehydrogenase conserved
RR42_RS15410 -2.1 -5.2 membrane protein compare
RR42_RS05955 -2.1 -1.7 hypothetical protein compare
RR42_RS17390 -2.1 -6.4 ATP-dependent DNA helicase RecG compare
RR42_RS14790 -2.1 -7.3 cobalamin biosynthesis protein CobD compare
RR42_RS00115 -2.1 -2.3 hypothetical protein compare
RR42_RS13555 -2.1 -8.6 anthraniloyl-CoA monooxygenase (EC 1.14.13.40) (from data) compare
RR42_RS04700 -1.9 -1.9 ribonuclease G compare
RR42_RS06545 -1.8 -2.3 thioesterase compare
RR42_RS16220 -1.8 -1.6 DNA polymerase III subunit chi compare
RR42_RS08450 -1.8 -2.2 hypothetical protein compare
RR42_RS04895 -1.8 -8.7 serine/threonine protein phosphatase compare
RR42_RS04590 -1.7 -7.0 AsnC family transcriptional regulator compare
RR42_RS02045 -1.7 -9.6 GTPase compare
RR42_RS04585 -1.7 -6.5 amino acid dehydrogenase compare
RR42_RS06020 -1.7 -1.1 Fe-S cluster assembly transcriptional regulator IscR compare
RR42_RS31285 -1.6 -2.2 XRE family transcriptional regulator compare
RR42_RS31530 -1.6 -3.6 histidine kinase compare
RR42_RS05920 -1.6 -3.9 HrcA family transcriptional regulator compare
RR42_RS17060 -1.6 -11.2 histidine kinase compare
RR42_RS01920 -1.6 -3.7 protoheme IX farnesyltransferase compare
RR42_RS19085 -1.5 -1.9 cytochrome C biogenesis protein ResB compare
RR42_RS06630 -1.5 -2.1 integration host factor subunit alpha compare
RR42_RS01905 -1.5 -3.3 cytochrome C oxidase subunit II compare
RR42_RS24535 -1.5 -1.4 tRNA-Asn compare
RR42_RS19090 -1.5 -2.1 cytochrome C compare
RR42_RS32520 -1.5 -3.5 cytochrome C compare
RR42_RS19655 -1.5 -1.5 tRNA-Ala compare
RR42_RS19635 -1.5 -2.3 hypothetical protein compare
RR42_RS17055 -1.5 -5.9 LuxR family transcriptional regulator compare
RR42_RS15465 -1.4 -2.9 TonB-dependent receptor compare
RR42_RS13540 -1.4 -3.1 acyl-CoA dehydrogenase compare
RR42_RS15090 -1.4 -4.6 DNA helicase compare
RR42_RS06395 -1.4 -5.5 TetR family transcriptional regulator compare
RR42_RS06095 -1.4 -4.1 hypothetical protein compare
RR42_RS23205 -1.4 -1.1 hypothetical protein compare
RR42_RS12925 -1.4 -2.3 ATPase compare
RR42_RS07615 -1.4 -1.4 3-ketoacyl-ACP reductase compare
RR42_RS01400 -1.4 -6.4 5-formyltetrahydrofolate cyclo-ligase compare
RR42_RS33215 -1.4 -7.6 transferase compare
RR42_RS01885 -1.4 -4.5 cytochrome C oxidase assembly protein compare
RR42_RS00725 -1.4 -2.5 hypothetical protein compare
RR42_RS15470 -1.3 -1.4 biopolymer transporter ExbD compare
RR42_RS11770 -1.3 -2.2 cyclase compare
RR42_RS10465 -1.3 -1.7 hypothetical protein compare
RR42_RS04145 -1.3 -1.4 peptidase A24 compare
RR42_RS24040 -1.2 -2.4 hypothetical protein compare
RR42_RS08700 -1.2 -2.5 hypothetical protein compare
RR42_RS15785 -1.2 -6.5 glycosyl transferase family 28 compare
RR42_RS05990 -1.2 -5.2 aromatic amino acid aminotransferase compare
RR42_RS15745 -1.2 -6.2 group1 glycosyl transferase compare
RR42_RS18820 -1.2 -4.9 cytochrome B compare
RR42_RS21820 -1.2 -3.3 GntR family transcriptional regulator compare
RR42_RS37410 -1.2 -3.6 PaaX family transcriptional regulator compare
RR42_RS10365 -1.2 -3.1 ABC transporter compare
RR42_RS19645 -1.1 -1.6 DNA topoisomerase compare
RR42_RS08210 -1.1 -1.1 hypothetical protein compare
RR42_RS02785 -1.1 -2.8 dimethyladenosine transferase compare
RR42_RS03140 -1.1 -4.8 molybdenum cofactor biosynthesis protein MoaC compare
RR42_RS30640 -1.1 -4.6 DNA mismatch repair protein MutT compare
RR42_RS13050 -1.1 -5.8 transaldolase compare
RR42_RS18815 -1.1 -3.5 cytochrome C compare
RR42_RS00790 -1.1 -4.6 chemotaxis protein CheY compare
RR42_RS35875 -1.1 -5.2 UDP-galactose-4-epimerase compare
RR42_RS21955 -1.1 -1.3 hypothetical protein compare
RR42_RS01875 -1.1 -3.2 cytochrome C oxidase subunit II compare
RR42_RS33195 -1.1 -5.8 UDP-sugar lipid carrier transferase compare
RR42_RS18825 -1.1 -2.8 ubiquinol-cytochrome C reductase compare
RR42_RS01910 -1.1 -4.2 cytochrome C oxidase subunit I compare
RR42_RS06870 -1.1 -1.7 hypothetical protein compare
RR42_RS09180 -1.1 -1.1 Rrf2 family transcriptional regulator compare
RR42_RS02150 -1.1 -2.2 membrane protein compare
RR42_RS19065 -1.1 -6.7 transcriptional regulator compare
RR42_RS15460 -1.1 -4.7 translocation protein TolB compare
RR42_RS07385 -1.1 -2.5 Phasin (PHA-granule associated protein) compare
RR42_RS35780 -1.1 -2.1 chemotaxis protein CheY compare
RR42_RS06880 -1.1 -0.9 hypothetical protein compare
RR42_RS07125 -1.1 -1.0 hypothetical protein compare
RR42_RS26935 -1.1 -4.0 farnesyl-diphosphate farnesyltransferase compare
RR42_RS01915 -1.1 -4.6 cytochrome C oxidase subunit I compare
RR42_RS32585 -1.0 -1.6 cytochrome C oxidase compare
RR42_RS04765 -1.0 -2.3 3-oxoacyl-ACP reductase compare
RR42_RS07360 -1.0 -2.2 ATPase compare
RR42_RS14055 -1.0 -2.5 elongation factor 4 compare
RR42_RS35975 -1.0 -2.6 pilus assembly protein TadC compare
RR42_RS22295 -1.0 -1.6 methionine sulfoxide reductase B compare
RR42_RS13670 -1.0 -4.4 hypothetical protein compare
RR42_RS34650 -1.0 -4.1 LacI family transcriptional regulator compare
RR42_RS08000 -1.0 -1.1 hypothetical protein compare
RR42_RS05890 -1.0 -4.7 glutamine-synthetase adenylyltransferase compare
RR42_RS29785 -1.0 -2.8 hypothetical protein compare
RR42_RS02250 -1.0 -2.3 GntR family transcriptional regulator compare
RR42_RS14760 -1.0 -3.3 molybdenum cofactor biosynthesis protein MogA compare
RR42_RS25755 -1.0 -2.6 IclR family transcriptional regulator compare
RR42_RS02950 -1.0 -1.2 malonate decarboxylase subunit beta compare
RR42_RS27530 -1.0 -2.2 hypothetical protein compare
RR42_RS20810 -1.0 -1.4 hypothetical protein compare
RR42_RS26590 -1.0 -1.4 hypothetical protein compare
RR42_RS17490 -1.0 -2.5 NADP transhydrogenase subunit alpha compare
RR42_RS02420 -0.9 -0.9 SAM-dependent methyltransferase compare
RR42_RS07565 -0.9 -4.0 transcription accessory protein compare
RR42_RS01255 -0.9 -4.6 lauroyl acyltransferase compare
RR42_RS29280 -0.9 -1.0 hypothetical protein compare
RR42_RS13535 -0.9 -6.1 2-aminobenzoate-CoA ligase (EC 6.2.1.32) (from data) compare
RR42_RS05485 -0.9 -1.2 polynucleotide phosphorylase/polyadenylase compare
RR42_RS13040 -0.9 -4.0 iron transporter compare
RR42_RS28155 -0.9 -2.5 hypothetical protein compare
RR42_RS21435 -0.9 -2.4 hypothetical protein compare
RR42_RS00285 -0.9 -2.4 thiamine biosynthesis protein ThiS compare
RR42_RS01380 -0.9 -1.0 membrane protein compare
RR42_RS13620 -0.9 -0.9 ferredoxin compare
RR42_RS16690 -0.9 -2.7 RNA signal recognition particle 4.5S RNA compare
RR42_RS02750 -0.9 -4.1 mannose-1-phosphate guanylyltransferase compare
RR42_RS32235 -0.9 -3.5 hopanoid biosynthesis associated radical SAM protein HpnH compare
RR42_RS36690 -0.9 -3.1 DNA alkylation repair protein compare
RR42_RS34940 -0.9 -2.3 bb3-type cytochrome oxidase subunit IV compare
RR42_RS17505 -0.9 -5.8 NAD synthetase compare
RR42_RS16510 -0.9 -1.7 hypothetical protein compare
RR42_RS12245 -0.9 -4.7 transcriptional regulator compare
RR42_RS04955 -0.9 -1.6 hypothetical protein compare
RR42_RS02440 -0.9 -2.0 membrane protein compare


Specific Phenotypes

For 5 genes in this experiment

For nitrogen source L-Tryptophan in Cupriavidus basilensis FW507-4G11

For nitrogen source L-Tryptophan across organisms