Experiment set2IT085 for Sphingomonas koreensis DSMZ 15582

Compare to:

LB with L-Lysine 25 mM

200 most detrimental genes:

  gene name fitness t score description  
Ga0059261_0208 +0.9 4.1 Response regulator receiver domain compare
Ga0059261_3579 +0.9 4.6 hypothetical protein compare
Ga0059261_3581 +0.8 5.8 Alpha/beta hydrolase family compare
Ga0059261_2713 +0.8 2.3 hypothetical protein compare
Ga0059261_0344 +0.8 1.8 Molecular chaperone (small heat shock protein) compare
Ga0059261_3491 +0.8 4.9 hypothetical protein compare
Ga0059261_1574 +0.7 2.9 Superfamily II DNA and RNA helicases compare
Ga0059261_1196 +0.7 2.3 hypothetical protein compare
Ga0059261_0393 +0.6 1.5 hypothetical protein compare
Ga0059261_3759 +0.6 1.8 hypothetical protein compare
Ga0059261_2929 +0.6 1.6 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) compare
Ga0059261_1022 +0.6 2.4 hypothetical protein compare
Ga0059261_1043 +0.6 2.3 Uncharacterized protein conserved in bacteria compare
Ga0059261_1050 +0.5 1.1 hypothetical protein compare
Ga0059261_2663 +0.5 1.2 Domain of unknown function (DUF718) compare
Ga0059261_1774 +0.5 1.5 hypothetical protein compare
Ga0059261_3909 +0.5 1.6 Predicted membrane protein compare
Ga0059261_0827 +0.5 2.0 hypothetical protein compare
Ga0059261_4185 +0.5 1.3 hypothetical protein compare
Ga0059261_1145 +0.5 1.4 flagella basal body P-ring formation protein FlgA compare
Ga0059261_0266 +0.5 0.9 hypothetical protein compare
Ga0059261_1071 +0.5 1.2 hypothetical protein compare
Ga0059261_0223 +0.5 1.8 Peptidase inhibitor I78 family compare
Ga0059261_3947 +0.5 1.6 type II secretion system protein I (GspI) compare
Ga0059261_1569 +0.5 1.9 Response regulator receiver domain compare
Ga0059261_3755 +0.5 1.2 Protein of unknown function (DUF2798) compare
Ga0059261_3289 +0.5 1.3 Predicted membrane protein compare
Ga0059261_1381 +0.5 2.4 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_1380 +0.5 3.5 Membrane protease subunits, stomatin/prohibitin homologs compare
Ga0059261_0725 +0.4 0.8 Fructose-1,6-bisphosphate aldolase compare
Ga0059261_3783 +0.4 1.9 hypothetical protein compare
Ga0059261_2478 +0.4 2.0 Uncharacterized conserved protein compare
Ga0059261_3872 +0.4 2.1 Outer membrane protein compare
Ga0059261_2018 +0.4 3.4 hypothetical protein compare
Ga0059261_3842 +0.4 4.0 PAS domain S-box compare
Ga0059261_1171 +0.4 2.4 Uncharacterized conserved protein compare
Ga0059261_3011 +0.4 2.0 arsenate reductase (glutaredoxin) compare
Ga0059261_1743 +0.4 1.5 hypothetical protein compare
Ga0059261_2973 +0.4 2.2 hypothetical protein compare
Ga0059261_2019 +0.4 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_3545 +0.4 1.1 hypothetical protein compare
Ga0059261_4083 +0.4 1.7 two component transcriptional regulator, LuxR family compare
Ga0059261_1195 +0.4 1.4 Co/Zn/Cd efflux system component compare
Ga0059261_0272 +0.4 1.3 Uncharacterized small protein compare
Ga0059261_0267 +0.4 1.0 Predicted membrane protein compare
Ga0059261_1610 +0.4 2.4 CBS domain/Transporter associated domain compare
Ga0059261_0816 +0.4 1.2 hypothetical protein compare
Ga0059261_1408 +0.4 0.6 Domain of unknown function (DUF4168) compare
Ga0059261_2795 +0.4 2.1 Predicted metal-dependent hydrolase of the TIM-barrel fold compare
Ga0059261_0062 +0.4 1.4 hypothetical protein compare
Ga0059261_2368 +0.4 0.9 Phage baseplate assembly protein W compare
Ga0059261_1763 +0.4 1.8 hypothetical protein compare
Ga0059261_1138 +0.4 1.5 hypothetical protein compare
Ga0059261_0957 +0.4 0.8 Protein of unknown function (DUF2798) compare
Ga0059261_0252 +0.3 0.9 SpoIIAA-like compare
Ga0059261_1962 +0.3 1.3 RNase HII (EC 3.1.26.4) compare
Ga0059261_0340 +0.3 1.7 Bacterial protein of unknown function (DUF937) compare
Ga0059261_3801 +0.3 1.8 Phosphate/sulphate permeases compare
Ga0059261_2743 +0.3 1.5 hypothetical protein compare
Ga0059261_3573 +0.3 2.5 Bacterial PH domain compare
Ga0059261_3107 +0.3 2.2 EPS-associated transcriptional regulator, MarR family compare
Ga0059261_2665 +0.3 2.3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Ga0059261_1772 +0.3 0.9 MobA/MobL family compare
Ga0059261_2020 +0.3 2.6 Glycosyltransferase compare
Ga0059261_2531 +0.3 1.0 conserved hypothetical integral membrane protein compare
Ga0059261_0627 +0.3 0.6 cobalamin-5'-phosphate synthase (EC 2.7.8.26) compare
Ga0059261_2730 +0.3 1.0 Sortase and related acyltransferases compare
Ga0059261_0921 +0.3 0.9 hypothetical protein compare
Ga0059261_3335 +0.3 1.2 hypothetical protein compare
Ga0059261_1389 +0.3 2.0 Mechanosensitive ion channel compare
Ga0059261_3125 +0.3 0.8 Imidazoleglycerol-phosphate synthase compare
Ga0059261_4171 +0.3 1.6 redox-sensitive transcriptional activator SoxR compare
Ga0059261_1035 +0.3 0.8 hypothetical protein compare
Ga0059261_3225 +0.3 2.3 Uncharacterized proteins of the AP superfamily compare
Ga0059261_2653 +0.3 1.8 Uncharacterized protein conserved in bacteria compare
Ga0059261_4029 +0.3 1.8 hypothetical protein compare
Ga0059261_0853 +0.3 1.4 peroxiredoxin, Ohr subfamily compare
Ga0059261_2916 +0.3 1.3 P-type conjugative transfer protein TrbJ compare
Ga0059261_1596 +0.3 1.2 CBS domain compare
Ga0059261_4001 +0.3 1.9 NTP pyrophosphohydrolases including oxidative damage repair enzymes compare
Ga0059261_0850 +0.3 0.8 hypothetical protein compare
Ga0059261_3882 +0.3 1.2 dimethyladenosine transferase (EC 2.1.1.-) compare
Ga0059261_3280 +0.3 0.7 Uncharacterized conserved protein compare
Ga0059261_3507 +0.3 2.5 His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/CHASE3 domain compare
Ga0059261_3948 +0.3 1.2 type II secretion system protein H compare
Ga0059261_0444 +0.3 1.2 Heavy-metal resistance compare
Ga0059261_2593 +0.3 1.1 hypothetical protein compare
Ga0059261_1217 +0.3 1.3 MobA/MobL family compare
Ga0059261_1904 +0.3 0.9 Asparaginase compare
Ga0059261_0305 +0.3 1.3 bacterioferritin compare
Ga0059261_3321 +0.3 0.9 pyrroline-5-carboxylate reductase compare
Ga0059261_0781 +0.3 0.8 hypothetical protein compare
Ga0059261_2215 +0.3 1.0 Thiamine monophosphate synthase compare
Ga0059261_3904 +0.3 1.2 Predicted membrane protein compare
Ga0059261_3006 +0.3 1.1 hypothetical protein compare
Ga0059261_3240 +0.3 1.8 Flp pilus assembly protein TadB compare
Ga0059261_2745 +0.3 2.3 Myo-inositol-1-phosphate synthase compare
Ga0059261_0439 +0.3 0.9 hypothetical protein compare
Ga0059261_0963 +0.3 1.4 hypothetical protein compare
Ga0059261_2266 +0.3 1.6 Uncharacterized protein conserved in bacteria compare
Ga0059261_0600 +0.3 1.7 CDP-glucose 4,6-dehydratase compare
Ga0059261_0028 +0.3 1.6 Predicted transcriptional regulators compare
Ga0059261_0360 +0.3 1.6 Putative NADH-flavin reductase compare
Ga0059261_0898 +0.3 1.0 Membrane protein implicated in regulation of membrane protease activity compare
Ga0059261_3906 +0.3 1.8 Transcriptional regulator compare
Ga0059261_3668 +0.3 1.3 ABC transporter compare
Ga0059261_1538 +0.3 1.1 Predicted transcriptional regulators compare
Ga0059261_1303 +0.3 1.6 hypothetical protein compare
Ga0059261_0294 +0.3 1.1 arsenate reductase (glutaredoxin) compare
Ga0059261_3219 +0.3 1.1 ubiquinol-cytochrome c reductase, iron-sulfur subunit compare
Ga0059261_0270 +0.3 1.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_0905 +0.3 1.5 Protein of unknown function (DUF998) compare
Ga0059261_2746 +0.3 1.4 Predicted sugar nucleotidyltransferases compare
Ga0059261_3257 +0.3 1.2 glycine cleavage system H protein compare
Ga0059261_0306 +0.3 1.5 FOG: HPt domain compare
Ga0059261_2086 +0.3 0.5 SAF-like compare
Ga0059261_1548 +0.3 1.5 Uncharacterized protein involved in tolerance to divalent cations compare
Ga0059261_3237 +0.3 1.3 hypothetical protein compare
Ga0059261_1530 +0.3 1.2 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Ga0059261_2840 +0.3 1.2 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_2097 +0.3 1.1 Rod binding protein compare
Ga0059261_1064 +0.2 1.0 Uncharacterized conserved protein compare
Ga0059261_1762 +0.2 0.6 hypothetical protein compare
Ga0059261_3877 +0.2 0.5 hypothetical protein compare
Ga0059261_3761 +0.2 1.9 hypothetical protein compare
Ga0059261_3431 +0.2 1.4 Uncharacterized protein conserved in bacteria compare
Ga0059261_2358 +0.2 1.8 Bacteriophage CI repressor helix-turn-helix domain compare
Ga0059261_3271 +0.2 0.4 arsenate reductase (glutaredoxin) compare
Ga0059261_2913 +0.2 0.8 Type IV secretory pathway, VirB2 components (pilins) compare
Ga0059261_2255 +0.2 0.8 nitrogen regulatory protein P-II family compare
Ga0059261_2570 +0.2 0.7 Type IV secretory pathway, TrbD component compare
Ga0059261_0651 +0.2 1.5 Methylase of chemotaxis methyl-accepting proteins compare
Ga0059261_4139 +0.2 0.7 hypothetical protein compare
Ga0059261_0379 +0.2 1.0 DNA binding domain, excisionase family compare
Ga0059261_3874 +0.2 1.5 ABC-type antimicrobial peptide transport system, ATPase component compare
Ga0059261_3285 +0.2 1.1 Acyl dehydratase compare
Ga0059261_3813 +0.2 1.6 Alcohol dehydrogenase GroES-like domain compare
Ga0059261_3287 +0.2 1.8 Topoisomerase IB compare
Ga0059261_0413 +0.2 1.7 N-acyl-L-homoserine lactone synthetase compare
Ga0059261_1355 +0.2 1.8 Cupin-like domain compare
Ga0059261_2894 +0.2 1.6 Helix-turn-helix domain compare
Ga0059261_0057 +0.2 2.1 Glycosyltransferase compare
Ga0059261_2347 +0.2 0.9 hypothetical protein compare
Ga0059261_2640 +0.2 1.1 Asp/Glu/Hydantoin racemase compare
Ga0059261_0387 +0.2 0.7 Type IV secretory pathway, TrbD component compare
Ga0059261_2717 +0.2 1.0 Biopolymer transport protein compare
Ga0059261_4227 +0.2 1.7 Uncharacterized protein conserved in bacteria compare
Ga0059261_0673 +0.2 1.3 hypothetical protein compare
Ga0059261_1758 +0.2 1.5 hypothetical protein compare
Ga0059261_4110 +0.2 1.4 Microcystin-dependent protein compare
Ga0059261_1680 +0.2 1.8 NAD-dependent aldehyde dehydrogenases compare
Ga0059261_1023 +0.2 1.9 Glycine zipper 2TM domain compare
Ga0059261_2600 +0.2 1.6 Protein of unknown function DUF262 compare
Ga0059261_1057 +0.2 1.0 hypothetical protein compare
Ga0059261_3963 +0.2 1.6 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
Ga0059261_3187 +0.2 1.2 Polysaccharide deacetylase compare
Ga0059261_2237 +0.2 1.5 Protein of unknown function (DUF1674) compare
Ga0059261_2587 +0.2 1.0 hypothetical protein compare
Ga0059261_3052 +0.2 1.3 Uncharacterized conserved protein (DUF2285) compare
Ga0059261_0025 +0.2 1.6 hypothetical protein compare
Ga0059261_0451 +0.2 0.8 hypothetical protein compare
Ga0059261_3038 +0.2 1.2 hypothetical protein compare
Ga0059261_2591 +0.2 1.9 Predicted transcriptional regulators compare
Ga0059261_1420 +0.2 1.5 Protein of unknown function (DUF2490) compare
Ga0059261_0833 +0.2 1.3 Glycerol kinase compare
Ga0059261_0406 +0.2 1.3 Predicted transcriptional regulators compare
Ga0059261_0450 +0.2 1.1 Putative copper export protein compare
Ga0059261_0400 +0.2 0.9 hypothetical protein compare
Ga0059261_2747 +0.2 1.5 Cupin domain compare
Ga0059261_1737 +0.2 1.2 hypothetical protein compare
Ga0059261_0139 +0.2 1.5 Signal transduction histidine kinase, nitrogen specific compare
Ga0059261_2861 +0.2 1.6 Enoyl-CoA hydratase/carnithine racemase compare
Ga0059261_1346 +0.2 1.7 hypothetical protein compare
Ga0059261_1182 +0.2 1.6 Predicted transcriptional regulators compare
Ga0059261_0246 +0.2 0.5 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD compare
Ga0059261_1336 +0.2 1.4 transcriptional regulator, HxlR family compare
Ga0059261_4047 +0.2 1.8 2OG-Fe(II) oxygenase superfamily compare
Ga0059261_2126 +0.2 1.1 ETC complex I subunit conserved region compare
Ga0059261_0686 +0.2 1.6 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Ga0059261_1400 +0.2 1.1 Glutathione S-transferase compare
Ga0059261_3670 +0.2 1.0 tRNA compare
Ga0059261_2995 +0.2 1.2 hypothetical protein compare
Ga0059261_1588 +0.2 1.3 Methyltransferase domain compare
Ga0059261_1620 +0.2 1.6 Predicted S-adenosylmethionine-dependent methyltransferase compare
Ga0059261_2275 +0.2 1.4 Predicted permeases compare
Ga0059261_2088 +0.2 0.9 Flagellar motor component compare
Ga0059261_3803 +0.2 1.2 RND family efflux transporter, MFP subunit compare
Ga0059261_1075 +0.2 0.5 Uncharacterized protein conserved in bacteria compare
Ga0059261_1571 +0.2 1.7 SapC compare
Ga0059261_1924 +0.2 1.9 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes compare
Ga0059261_2058 +0.2 1.7 Flagellar capping protein compare
Ga0059261_0993 +0.2 0.4 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Ga0059261_3978 +0.2 1.4 Histidine phosphatase superfamily (branch 1) compare
Ga0059261_2935 +0.2 1.2 hypothetical protein compare
Ga0059261_0584 +0.2 1.5 RNA polymerase sigma factor, sigma-70 family compare
Ga0059261_0556 +0.2 0.9 Signal transduction histidine kinase compare
Ga0059261_4225 +0.2 1.1 3-isopropylmalate dehydratase, small subunit compare
Ga0059261_0812 +0.2 0.7 Short-chain alcohol dehydrogenase of unknown specificity compare
Ga0059261_2109 +0.2 0.8 hypothetical protein compare
Ga0059261_0745 +0.2 0.6 Uncharacterized membrane protein, required for colicin V production compare


Specific Phenotypes

For 2 genes in this experiment

For stress L-Lysine in Sphingomonas koreensis DSMZ 15582

For stress L-Lysine across organisms