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Experiment set2IT070 for
Methanococcus maripaludis JJ
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H2 McCas, 2.5g/L bicarb, 200 mM MOPs, 40 psi H2CO2
200 most important genes:
gene
name
fitness
t score
description
MMJJ
_RS03115
-6.6
-6.8
sulfopyruvate decarboxylase subunit alpha
compare
MMJJ
_RS03055
-5.5
-2.8
hypothetical protein
compare
MMJJ
_RS03065
-5.2
-16.6
CBS domain-containing protein
compare
MMJJ
_RS03895
-5.1
-3.1
hydrogenase expression/formation protein HypE
compare
MMJJ
_RS06270
-5.1
-3.5
dethiobiotin synthase
compare
MMJJ
_RS00580
-5.0
-1.9
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG
compare
MMJJ
_RS06600
-5.0
-2.5
DUF555 domain-containing protein
compare
MMJJ
_RS00645
-5.0
-10.1
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMJJ
_RS06260
-5.0
-7.6
6-carboxyhexanoate--CoA ligase
compare
MMJJ
_RS03170
-4.9
-9.5
DUF5612 domain-containing protein
compare
MMJJ
_RS08080
-4.8
-9.8
TIGR00300 family protein
compare
MMJJ
_RS06375
-4.8
-3.2
UbiX family flavin prenyltransferase
compare
MMJJ
_RS04800
-4.8
-4.6
2-phospho-L-lactate guanylyltransferase
compare
MMJJ
_RS03630
-4.8
-13.3
AMP phosphorylase
compare
MMJJ
_RS07720
-4.7
-2.1
UPF0058 family protein
compare
MMJJ
_RS02045
-4.7
-2.6
molybdenum cofactor guanylyltransferase
compare
MMJJ
_RS06265
-4.7
-13.1
8-amino-7-oxononanoate synthase
compare
MMJJ
_RS08035
-4.6
-8.5
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMJJ
_RS04200
-4.6
-5.5
triphosphoribosyl-dephospho-CoA synthase
compare
MMJJ
_RS03620
-4.6
-4.5
DUF2097 domain-containing protein
compare
MMJJ
_RS00570
-4.6
-1.8
ribonuclease P
compare
MMJJ
_RS05535
-4.6
-14.3
hypothetical protein
compare
MMJJ
_RS06155
-4.5
-3.1
phosphatidylglycerophosphatase A
compare
MMJJ
_RS09375
-4.5
-1.7
hypothetical protein
compare
MMJJ
_RS02200
-4.5
-7.4
chorismate pyruvate-lyase family protein
compare
MMJJ
_RS04685
-4.5
-6.1
carbamoyltransferase HypF
compare
MMJJ
_RS08625
-4.5
-3.1
magnesium/cobalt transporter CorA
compare
MMJJ
_RS00235
-4.4
-18.6
hypothetical protein
compare
MMJJ
_RS08155
-4.4
-3.0
cobalt-precorrin-5B (C(1))-methyltransferase CbiD
compare
MMJJ
_RS01350
-4.4
-4.2
sodium:proton antiporter
compare
MMJJ
_RS04145
-4.3
-10.0
glutamate-1-semialdehyde 2,1-aminomutase
compare
MMJJ
_RS03125
-4.3
-3.0
GMC oxidoreductase
compare
MMJJ
_RS02985
-4.3
-17.4
MBL fold metallo-hydrolase
compare
MMJJ
_RS06695
-4.3
-2.6
amidohydrolase
compare
MMJJ
_RS06510
-4.3
-2.4
LL-diaminopimelate aminotransferase
compare
MMJJ
_RS01935
-4.2
-2.9
O-phosphoseryl-tRNA(Sec) selenium transferase
compare
MMJJ
_RS00600
-4.2
-2.3
hydroxymethylbilane synthase
compare
MMJJ
_RS03800
-4.2
-12.4
aldolase
compare
MMJJ
_RS02090
-4.2
-4.1
tyramine--L-glutamate ligase
compare
MMJJ
_RS07005
-4.2
-5.2
transcription factor S
compare
MMJJ
_RS05575
-4.2
-4.0
2-amino-5-formylamino-6-ribosylaminopyrimidin- 4(3H)-one 5'-monophosphate deformylase
compare
MMJJ
_RS07980
-4.1
-13.5
biotin synthase BioB
compare
MMJJ
_RS04980
-4.1
-5.6
bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase
compare
MMJJ
_RS03965
-4.1
-1.6
DNA-directed RNA polymerase subunit L
compare
MMJJ
_RS00560
-4.1
-3.9
homoisocitrate dehydrogenase
compare
MMJJ
_RS04155
-4.1
-4.0
hypothetical protein
compare
MMJJ
_RS03920
-4.1
-14.0
nickel pincer cofactor biosynthesis protein LarC
compare
MMJJ
_RS08535
-4.1
-2.6
NOL1/NOP2/sun family putative RNA methylase
compare
MMJJ
_RS06040
-4.1
-2.7
NADH-quinone oxidoreductase subunit H
compare
MMJJ
_RS01750
-4.1
-2.2
ferrous iron transport protein A
compare
MMJJ
_RS05770
-4.0
-2.8
flagellar protein D
compare
MMJJ
_RS03060
-4.0
-2.4
methanogenesis marker 7 protein
compare
MMJJ
_RS07375
-4.0
-10.6
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMJJ
_RS04680
-4.0
-11.7
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMJJ
_RS04595
-4.0
-4.7
hypothetical protein
compare
MMJJ
_RS01880
-4.0
-2.4
RlmE family RNA methyltransferase
compare
MMJJ
_RS02040
-4.0
-2.4
Asp-tRNA(Asn) amidotransferase subunit GatC
compare
MMJJ
_RS06930
-3.9
-2.2
type II methionyl aminopeptidase
compare
MMJJ
_RS03760
-3.9
-2.6
hydrogenase maturation nickel metallochaperone HypA
compare
MMJJ
_RS06625
-3.9
-1.8
pyruvate synthase subunit PorB
compare
MMJJ
_RS07950
-3.9
-3.1
4Fe-4S binding protein
compare
MMJJ
_RS04700
-3.9
-5.4
deoxyhypusine synthase
compare
MMJJ
_RS04730
-3.9
-2.3
tyrosine decarboxylase MfnA
compare
MMJJ
_RS07245
-3.9
-5.3
amidohydrolase family protein
compare
MMJJ
_RS03765
-3.9
-8.2
hypothetical protein
compare
MMJJ
_RS05590
-3.9
-1.7
homoserine dehydrogenase
compare
MMJJ
_RS07470
-3.8
-1.7
50S ribosome-binding GTPase
compare
MMJJ
_RS03095
-3.8
-2.1
bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase
compare
MMJJ
_RS07190
-3.8
-2.6
RtcB family protein
compare
MMJJ
_RS05445
-3.8
-1.7
2-oxoacid:acceptor oxidoreductase subunit alpha
compare
MMJJ
_RS08660
-3.7
-2.5
acetylornithine transaminase
compare
MMJJ
_RS05650
-3.7
-2.4
formylmethanofuran dehydrogenase subunit B
compare
MMJJ
_RS03200
-3.7
-1.9
uroporphyrinogen-III synthase
compare
MMJJ
_RS07945
-3.7
-2.2
4Fe-4S binding protein
compare
MMJJ
_RS03615
-3.7
-2.2
cobalt-precorrin-8 methylmutase
compare
MMJJ
_RS03540
-3.7
-7.6
TIGR00289 family protein
compare
MMJJ
_RS07000
-3.7
-1.6
TrkH family potassium uptake protein
compare
MMJJ
_RS01600
-3.7
-2.2
radical SAM protein
compare
MMJJ
_RS07415
-3.7
-2.0
polyprenyl diphosphate synthase
compare
MMJJ
_RS08840
-3.7
-2.5
calcium/sodium antiporter
compare
MMJJ
_RS03670
-3.7
-2.5
precorrin-2 C(20)-methyltransferase
compare
MMJJ
_RS03110
-3.7
-3.5
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase
compare
MMJJ
_RS04650
-3.7
-4.3
nitrogenase iron protein
compare
MMJJ
_RS08655
-3.6
-13.7
phospholipase D-like domain-containing protein
compare
MMJJ
_RS03005
-3.6
-2.5
Ni-sirohydrochlorin a,c-diamide reductive cyclase catalytic subunit
compare
MMJJ
_RS00275
-3.6
-1.8
coenzyme F420-0:L-glutamate ligase
compare
MMJJ
_RS07160
-3.6
-19.7
M20 family metallo-hydrolase
compare
MMJJ
_RS07410
-3.6
-3.5
methanogenesis marker protein Mmp4/MtxX
compare
MMJJ
_RS06240
-3.6
-2.0
dihydropteroate synthase-like protein
compare
MMJJ
_RS06715
-3.6
-11.1
lactaldehyde dehydrogenase
compare
MMJJ
_RS01810
-3.6
-1.9
methyl coenzyme M reductase system, component A2
compare
MMJJ
_RS06750
-3.6
-2.5
homoaconitase large subunit
compare
MMJJ
_RS06760
-3.5
-2.4
Ni-sirohydrochlorin a,c-diamide synthase
compare
MMJJ
_RS07350
-3.5
-3.5
4Fe-4S binding protein
compare
MMJJ
_RS05950
-3.5
-2.4
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
MMJJ
_RS02855
-3.5
-11.8
DEAD/DEAH box helicase
compare
MMJJ
_RS09135
-3.5
-9.8
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMJJ
_RS04485
-3.5
-9.2
riboflavin synthase
compare
MMJJ
_RS05995
-3.5
-1.8
ATP-binding cassette domain-containing protein
compare
MMJJ
_RS01990
-3.5
-8.5
universal stress protein
compare
MMJJ
_RS05935
-3.5
-1.8
Era-like GTP-binding protein
compare
MMJJ
_RS03580
-3.5
-2.2
TIGR00303 family protein
compare
MMJJ
_RS06255
-3.5
-5.8
tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3
compare
MMJJ
_RS03190
-3.5
-2.2
phosphopyruvate hydratase
compare
MMJJ
_RS05065
-3.5
-4.0
(4-{4-[2-(gamma-L- glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
compare
MMJJ
_RS06215
-3.5
-3.3
agmatinase
compare
MMJJ
_RS01755
-3.5
-2.1
ferrous iron transport protein B
compare
MMJJ
_RS05610
-3.4
-2.4
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMJJ
_RS07360
-3.4
-1.8
TIGR00269 family protein
compare
MMJJ
_RS08330
-3.4
-2.2
SufD family Fe-S cluster assembly protein
compare
MMJJ
_RS05380
-3.4
-1.1
hypothetical protein
compare
MMJJ
_RS06725
-3.4
-13.6
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMJJ
_RS04975
-3.4
-1.7
glycosyltransferase family 4 protein
compare
MMJJ
_RS05720
-3.4
-2.0
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMJJ
_RS06225
-3.4
-1.7
adenosylmethionine decarboxylase
compare
MMJJ
_RS03840
-3.4
-2.3
DHH family phosphoesterase
compare
MMJJ
_RS03150
-3.4
-6.7
2-phospho-L-lactate transferase
compare
MMJJ
_RS06860
-3.4
-4.5
hypothetical protein
compare
MMJJ
_RS07430
-3.4
-3.0
ribonuclease VapC
compare
MMJJ
_RS00125
-3.4
-2.0
KEOPS complex subunit Cgi121
compare
MMJJ
_RS05415
-3.3
-1.7
hypothetical protein
compare
MMJJ
_RS00355
-3.3
-2.8
ribonuclease P protein component 4
compare
MMJJ
_RS08095
-3.3
-3.2
cobyric acid synthase CobQ
compare
MMJJ
_RS08000
-3.3
-9.7
HesA/MoeB/ThiF family protein
compare
MMJJ
_RS05620
-3.3
-2.3
CoB--CoM heterodisulfide reductase iron-sulfur subunit A family protein
compare
MMJJ
_RS04995
-3.3
-5.0
Tfx family DNA-binding protein
compare
MMJJ
_RS08430
-3.3
-7.2
small nuclear ribonucleoprotein
compare
MMJJ
_RS08925
-3.3
-11.9
winged helix-turn-helix transcriptional regulator
compare
MMJJ
_RS09055
-3.3
-9.8
NFACT family protein
compare
MMJJ
_RS06485
-3.3
-2.1
phosphoglycerate kinase
compare
MMJJ
_RS06490
-3.3
-1.9
methanogenesis marker 2 protein
compare
MMJJ
_RS03865
-3.3
-1.2
phosphoribosyl-AMP cyclohydrolase
compare
MMJJ
_RS05360
-3.3
-6.0
nickel-responsive transcriptional regulator NikR
compare
MMJJ
_RS03310
-3.3
-3.1
hypothetical protein
compare
MMJJ
_RS08795
-3.2
-1.9
phosphoglucosamine mutase
compare
MMJJ
_RS07155
-3.2
-10.9
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMJJ
_RS08010
-3.2
-7.8
phosphoadenosine phosphosulfate reductase family protein
compare
MMJJ
_RS07455
-3.2
-6.7
coenzyme F420-reducing hydrogenase, FrhD protein
compare
MMJJ
_RS06840
-3.2
-3.1
nickel-dependent hydrogenase large subunit
compare
MMJJ
_RS00425
-3.2
-2.9
hypothetical protein
compare
MMJJ
_RS07705
-3.1
-2.1
GTP-binding protein EngB
compare
MMJJ
_RS00210
-3.1
-1.6
DUF530 family protein
compare
MMJJ
_RS00475
-3.1
-1.9
bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
compare
MMJJ
_RS00370
-3.1
-1.9
asparagine synthase (glutamine-hydrolyzing)
compare
MMJJ
_RS08320
-3.0
-1.5
CDP-diacylglycerol--serine O-phosphatidyltransferase
compare
MMJJ
_RS04005
-3.0
-14.3
acetate--CoA ligase family protein
compare
MMJJ
_RS01870
-3.0
-2.1
methanogenesis marker 15 protein
compare
MMJJ
_RS01690
-3.0
-3.2
methanogenesis marker 12 protein
compare
MMJJ
_RS00205
-3.0
-5.8
adenosylcobinamide-phosphate synthase CbiB
compare
MMJJ
_RS05070
-3.0
-2.0
DNA primase catalytic subunit PriS
compare
MMJJ
_RS00935
-3.0
-9.8
nickel pincer cofactor biosynthesis protein LarB
compare
MMJJ
_RS04520
-3.0
-5.3
coenzyme F430 synthase
compare
MMJJ
_RS05450
-3.0
-16.4
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMJJ
_RS05655
-3.0
-7.5
HisA/HisF family protein
compare
MMJJ
_RS06700
-3.0
-5.9
L-seryl-tRNA(Sec) kinase
compare
MMJJ
_RS03650
-3.0
-7.7
class I SAM-dependent methyltransferase family protein
compare
MMJJ
_RS05490
-3.0
-1.9
imidazole glycerol phosphate synthase subunit HisF
compare
MMJJ
_RS08500
-3.0
-7.3
L-sulfolactate dehydrogenase
compare
MMJJ
_RS01360
-2.9
-1.6
UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
compare
MMJJ
_RS00270
-2.9
-2.9
adenosylcobinamide-GDP ribazoletransferase
compare
MMJJ
_RS05375
-2.9
-13.3
radical SAM protein
compare
MMJJ
_RS02920
-2.9
-1.7
30S ribosomal protein S27ae
compare
MMJJ
_RS07345
-2.9
-9.1
homocysteine biosynthesis protein
compare
MMJJ
_RS08850
-2.9
-2.2
succinate dehydrogenase/fumarate reductase iron-sulfur subunit
compare
MMJJ
_RS09175
-2.9
-0.9
anthranilate synthase component I
compare
MMJJ
_RS04475
-2.9
-4.5
3,4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMJJ
_RS03785
-2.9
-2.4
hypothetical protein
compare
MMJJ
_RS05765
-2.9
-0.9
flagellar protein E
compare
MMJJ
_RS04010
-2.8
-6.5
archaeal proteasome endopeptidase complex subunit alpha
compare
MMJJ
_RS00450
-2.8
-1.7
DUF126 domain-containing protein
compare
MMJJ
_RS04770
-2.8
-4.3
formate-dependent phosphoribosylglycinamide formyltransferase
compare
MMJJ
_RS06175
-2.8
-2.0
DUF1743 domain-containing protein
compare
MMJJ
_RS07975
-2.8
-7.0
ATP-dependent sacrificial sulfur transferase LarE
compare
MMJJ
_RS08340
-2.8
-6.1
archaeoflavoprotein AfpA
compare
MMJJ
_RS06805
-2.8
-2.7
monovalent cation/H+ antiporter subunit E
compare
MMJJ
_RS06180
-2.8
-2.4
tryptophan--tRNA ligase
compare
MMJJ
_RS00215
-2.8
-2.0
CCA tRNA nucleotidyltransferase
compare
MMJJ
_RS02275
-2.8
-3.8
nucleotidyltransferase domain-containing protein
compare
MMJJ
_RS03660
-2.8
-3.3
DUF447 family protein
compare
MMJJ
_RS05155
-2.7
-6.2
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
compare
MMJJ
_RS06705
-2.7
-3.7
bifunctional NADP phosphatase/NAD kinase
compare
MMJJ
_RS01410
-2.7
-5.2
archaeal proteasome endopeptidase complex subunit beta
compare
MMJJ
_RS03270
-2.7
-1.9
ribosome biogenesis/translation initiation ATPase RLI
compare
MMJJ
_RS07170
-2.7
-4.4
pyridoxal phosphate-dependent aminotransferase
compare
MMJJ
_RS04150
-2.7
-2.6
DUF5379 domain-containing protein
compare
MMJJ
_RS03820
-2.7
-2.6
hydrogenase formation protein HypD
compare
MMJJ
_RS06030
-2.7
-4.4
4Fe-4S binding protein
compare
MMJJ
_RS01200
-2.7
-2.5
PRC-barrel domain-containing protein
compare
MMJJ
_RS09190
-2.7
-1.7
tryptophan synthase subunit beta
compare
MMJJ
_RS00995
-2.6
-7.5
TetR/AcrR family transcriptional regulator
compare
MMJJ
_RS04565
-2.6
-3.4
sirohydrochlorin nickelochelatase
compare
MMJJ
_RS03875
-2.6
-3.6
CBS domain-containing protein
compare
MMJJ
_RS06220
-2.6
-4.6
polyamine aminopropyltransferase
compare
MMJJ
_RS07785
-2.6
-1.5
fumarate reductase subunit A
compare
MMJJ
_RS08250
-2.6
-5.9
hydrogenase maturation peptidase HycI
compare
MMJJ
_RS01345
-2.6
-4.8
(5-formylfuran-3-yl)methyl phosphate synthase
compare
MMJJ
_RS04505
-2.5
-6.6
CDC48 family AAA ATPase
compare
MMJJ
_RS06250
-2.5
-2.1
nicotinamide-nucleotide adenylyltransferase
compare
MMJJ
_RS08870
-2.5
-1.2
2-isopropylmalate synthase
compare
MMJJ
_RS08055
-2.5
-6.4
methanogenesis marker 14 protein
compare
Specific Phenotypes
For 7 genes in this experiment