Experiment set2IT067 for Herbaspirillum seropedicae SmR1

Compare to:

LB with Cobalt chloride hexahydrate 0.2 mM

200 most detrimental genes:

  gene name fitness t score description  
HSERO_RS02000 +4.2 16.4 magnesium transporter conserved
HSERO_RS15600 +3.2 14.5 cytosol aminopeptidase compare
HSERO_RS03595 +3.2 11.9 cation transporter compare
HSERO_RS21450 +2.5 10.3 lipid A biosynthesis acyltransferase compare
HSERO_RS05435 +2.5 13.9 hemolysin protein conserved
HSERO_RS08535 +2.3 9.8 glycine/betaine ABC transporter substrate-binding protein compare
HSERO_RS07300 +2.3 5.5 glutamate--cysteine ligase compare
HSERO_RS09780 +2.0 1.6 phosphoglycerate mutase compare
HSERO_RS08530 +1.8 2.9 glycine/betaine ABC transporter permease compare
HSERO_RS21150 +1.8 7.8 aldolase compare
HSERO_RS22980 +1.8 10.1 membrane protein compare
HSERO_RS09335 +1.7 3.6 DNA-3-methyladenine glycosylase compare
HSERO_RS16835 +1.7 3.7 phosphatidylglycerophosphatase compare
HSERO_RS18935 +1.6 6.2 LysR family transcriptional regulator compare
HSERO_RS03435 +1.5 2.8 bacterioferritin compare
HSERO_RS00435 +1.5 6.5 glutathione synthetase compare
HSERO_RS20985 +1.5 3.0 serine acetyltransferase compare
HSERO_RS18115 +1.5 2.6 hypothetical protein compare
HSERO_RS02350 +1.5 7.4 diadenosine tetraphosphatase compare
HSERO_RS00250 +1.4 3.2 iron transporter compare
HSERO_RS17985 +1.4 5.5 tRNA pseudouridine synthase B compare
HSERO_RS13315 +1.3 1.6 ferredoxin compare
HSERO_RS09245 +1.3 2.2 carboxylesterase compare
HSERO_RS21445 +1.3 1.3 lipid A biosynthesis acyltransferase compare
HSERO_RS08145 +1.3 1.9 damage-inducible protein compare
HSERO_RS10400 +1.2 5.3 inorganic phosphate transporter compare
HSERO_RS10870 +1.2 6.7 methionine aminopeptidase compare
HSERO_RS01825 +1.2 4.4 RNA pyrophosphohydrolase compare
HSERO_RS02430 +1.2 2.6 sulfurtransferase compare
HSERO_RS16470 +1.2 4.1 tryptophan synthase subunit alpha compare
HSERO_RS21795 +1.2 2.4 CoA-binding protein compare
HSERO_RS08385 +1.2 5.5 anaerobic (selenocysteine-containing) formate dehydrogenase compare
HSERO_RS04235 +1.2 5.9 C4-dicarboxylate ABC transporter compare
HSERO_RS12960 +1.2 2.5 hypothetical protein compare
HSERO_RS23525 +1.2 3.0 hypothetical protein compare
HSERO_RS23610 +1.2 2.1 urease subunit gamma compare
HSERO_RS01050 +1.2 2.6 baseplate protein compare
HSERO_RS09660 +1.2 2.5 ribonuclease III compare
HSERO_RS09405 +1.2 3.7 molybdenum cofactor biosynthesis protein MoeA compare
HSERO_RS16275 +1.1 1.7 5-hydroxyisourate hydrolase compare
HSERO_RS01140 +1.1 2.3 phage tail protein compare
HSERO_RS12965 +1.1 3.9 phytoene synthase compare
HSERO_RS19535 +1.1 1.7 nucleotide-binding protein compare
HSERO_RS11100 +1.1 2.2 plasmid stabilization protein compare
HSERO_RS00810 +1.1 1.7 glutaredoxin compare
HSERO_RS16825 +1.1 2.3 NADP-dependent malic enzyme oxidoreductase compare
HSERO_RS02140 +1.0 1.1 thiamine-phosphate synthase compare
HSERO_RS18740 +1.0 1.8 hypothetical protein compare
HSERO_RS14745 +1.0 3.8 nicotinate phosphoribosyltransferase compare
HSERO_RS19140 +1.0 5.1 Rieske (2Fe-2S) protein compare
HSERO_RS05980 +1.0 1.5 aldehyde dehydrogenase compare
HSERO_RS04065 +1.0 2.0 pilus biosynthesis protein PilS compare
HSERO_RS01775 +1.0 5.5 hypothetical protein compare
HSERO_RS00260 +1.0 2.7 hypothetical protein compare
HSERO_RS21620 +1.0 4.3 amino acid ABC transporter permease compare
HSERO_RS10125 +1.0 1.9 chemotaxis protein compare
HSERO_RS13105 +1.0 3.4 C4-dicarboxylate ABC transporter compare
HSERO_RS03510 +1.0 4.0 proline aminopeptidase P II compare
HSERO_RS02005 +1.0 2.4 membrane protein compare
HSERO_RS13035 +0.9 2.9 hypothetical protein compare
HSERO_RS15095 +0.9 2.4 AraC family transcriptional regulator compare
HSERO_RS10580 +0.9 3.5 molybdate ABC transporter substrate-binding protein compare
HSERO_RS18675 +0.9 1.8 hypothetical protein compare
HSERO_RS00080 +0.9 4.2 histidine kinase compare
HSERO_RS18845 +0.9 2.2 hypothetical protein compare
HSERO_RS19275 +0.9 2.2 acyl-CoA hydrolase compare
HSERO_RS02800 +0.9 1.3 hypothetical protein compare
HSERO_RS14695 +0.9 2.4 ABC transporter permease compare
HSERO_RS21405 +0.9 3.4 glutathione S-transferase compare
HSERO_RS05040 +0.9 1.7 (2Fe-2S)-binding protein compare
HSERO_RS09445 +0.9 3.3 iron deficiency-induced protein A compare
HSERO_RS12975 +0.9 1.0 phytoene synthase compare
HSERO_RS03875 +0.9 1.1 hypothetical protein compare
HSERO_RS06960 +0.9 1.7 chemotaxis protein CheY compare
HSERO_RS20705 +0.9 1.6 cobyrinic acid a,c-diamide synthase compare
HSERO_RS07855 +0.9 2.8 cysteine desulfurase compare
HSERO_RS16035 +0.9 1.5 cytochrome C oxidase compare
HSERO_RS07435 +0.9 2.6 formate dehydrogenase accessory protein FdhD compare
HSERO_RS07025 +0.9 1.9 ATP-dependent Clp protease ClpS compare
HSERO_RS13340 +0.9 1.0 hypothetical protein compare
HSERO_RS13250 +0.9 2.6 oxygen-insensitive nitroreductase compare
HSERO_RS20920 +0.9 3.0 3-dehydroquinate synthase compare
HSERO_RS07970 +0.9 1.2 formyltetrahydrofolate deformylase compare
HSERO_RS19770 +0.9 1.2 hypothetical protein compare
HSERO_RS13270 +0.9 2.9 bifunctional precorrin-3 methyltransferase/precorrin-6x reductase oxidoreductase compare
HSERO_RS01935 +0.9 1.3 3-dehydroquinate dehydratase compare
HSERO_RS05890 +0.8 0.8 3-hydroxy-2-methylbutyryl-CoA dehydrogenase compare
HSERO_RS05970 +0.8 0.9 ABC transporter compare
HSERO_RS07265 +0.8 3.8 aspartyl/asparaginyl beta-hydroxylase AspH compare
HSERO_RS11980 +0.8 2.0 hypothetical protein compare
HSERO_RS00175 +0.8 2.5 RNA polymerase sigma factor compare
HSERO_RS03145 +0.8 2.9 poly(A) polymerase compare
HSERO_RS01605 +0.8 3.4 amino acid dehydrogenase compare
HSERO_RS14690 +0.8 2.9 amino acid ABC transporter periplasmic protein compare
HSERO_RS10575 +0.8 1.9 molybdate ABC transporter permease compare
HSERO_RS06145 +0.8 0.6 NrdR family transcriptional regulator compare
HSERO_RS12865 +0.8 1.3 spore coat protein compare
HSERO_RS16590 +0.8 2.4 ABC transporter ATP-binding protein compare
HSERO_RS03940 +0.8 1.9 hypothetical protein compare
HSERO_RS00255 +0.8 4.7 iron transporter FeoB compare
HSERO_RS10545 +0.8 4.9 protein disaggregation chaperone compare
HSERO_RS16480 +0.8 1.2 N-(5'-phosphoribosyl)anthranilate isomerase compare
HSERO_RS03915 +0.8 1.5 hypothetical protein compare
HSERO_RS06530 +0.8 0.9 muconolactone delta-isomerase compare
HSERO_RS21525 +0.8 2.7 alpha/beta hydrolase compare
HSERO_RS21735 +0.8 2.1 hypothetical protein compare
HSERO_RS23655 +0.8 1.6 phosphonate ABC transporter permease compare
HSERO_RS02065 +0.8 1.7 hypothetical protein compare
HSERO_RS08345 +0.8 2.2 AraC family transcriptional regulator compare
HSERO_RS06320 +0.8 2.4 phosphate transport system permease PstA compare
HSERO_RS18230 +0.8 1.5 pilus assembly protein compare
HSERO_RS17220 +0.8 1.3 membrane protein compare
HSERO_RS14845 +0.8 2.6 stationary phase survival protein SurE compare
HSERO_RS17855 +0.8 3.0 DEAD/DEAH box helicase compare
HSERO_RS00410 +0.8 0.9 phosphoheptose isomerase compare
HSERO_RS17080 +0.8 1.6 hypothetical protein compare
HSERO_RS02105 +0.8 1.6 hypothetical protein compare
HSERO_RS07400 +0.7 0.9 LysR family transcriptional regulator compare
HSERO_RS14395 +0.7 1.8 oxygen-binding protein compare
HSERO_RS06745 +0.7 0.8 hypothetical protein compare
HSERO_RS02665 +0.7 2.6 hypothetical protein compare
HSERO_RS17485 +0.7 1.0 transcription regulator protein compare
HSERO_RS21160 +0.7 3.0 3-hydroxyisobutyrate dehydrogenase compare
HSERO_RS11595 +0.7 1.1 ArsR family transcriptional regulator compare
HSERO_RS09400 +0.7 1.9 molybdopterin-guanine dinucleotide biosynthesis protein A compare
HSERO_RS09835 +0.7 1.2 hypothetical protein compare
HSERO_RS02175 +0.7 1.4 NmrA family transcriptional regulator compare
HSERO_RS05140 +0.7 1.2 MarR family transcriptional regulator compare
HSERO_RS10090 +0.7 2.1 oxidoreductase compare
HSERO_RS02690 +0.7 3.2 taurine ABC transporter permease compare
HSERO_RS08075 +0.7 0.7 ferredoxin compare
HSERO_RS02445 +0.7 1.5 proteinase inhibitor compare
HSERO_RS03120 +0.7 1.6 chemotaxis protein CheW compare
HSERO_RS04150 +0.7 1.0 hypothetical protein compare
HSERO_RS03665 +0.7 3.3 oxidoreductase compare
HSERO_RS22285 +0.7 1.0 GntR family transcriptional regulator compare
HSERO_RS03300 +0.7 1.7 molybdenum cofactor biosynthesis protein MoaC compare
HSERO_RS02415 +0.7 4.2 hemolysin D compare
HSERO_RS02135 +0.7 2.9 phosphomethylpyrimidine kinase compare
HSERO_RS07225 +0.7 1.8 DNA-3-methyladenine glycosylase compare
HSERO_RS16475 +0.7 1.6 tryptophan synthase subunit alpha compare
HSERO_RS06640 +0.7 1.1 N-carbamoylsarcosine amidase compare
HSERO_RS14275 +0.7 1.9 nitrogen fixation protein NifX compare
HSERO_RS12265 +0.7 2.7 histidine kinase compare
HSERO_RS04230 +0.7 2.4 LuxR family transcriptional regulator compare
HSERO_RS11835 +0.7 1.5 hypothetical protein compare
HSERO_RS09485 +0.7 2.2 DNA mismatch repair protein MutS compare
HSERO_RS19155 +0.7 1.4 LysR family transcriptional regulator compare
HSERO_RS16615 +0.7 2.2 LysR family transcriptional regulator compare
HSERO_RS08425 +0.7 1.8 hypothetical protein compare
HSERO_RS13145 +0.7 1.4 histidine kinase compare
HSERO_RS18550 +0.7 1.0 excinuclease ATPase subunit compare
HSERO_RS03395 +0.7 2.3 peptide methionine sulfoxide reductase compare
HSERO_RS23560 +0.6 2.1 MFS transporter compare
HSERO_RS10080 +0.6 1.4 hypothetical protein compare
HSERO_RS13305 +0.6 2.1 magnesium chelatase compare
HSERO_RS10960 +0.6 1.7 PEP synthetase regulatory protein compare
HSERO_RS12920 +0.6 0.7 trigger factor compare
HSERO_RS19160 +0.6 2.6 divalent cation transporter compare
HSERO_RS20700 +0.6 1.9 zinc protease compare
HSERO_RS12560 +0.6 1.5 antitoxin compare
HSERO_RS08170 +0.6 1.7 S-adenosyl-L-methionine (SAM)-dependent methyltransferase PhcB compare
HSERO_RS08770 +0.6 2.2 membrane protein compare
HSERO_RS13260 +0.6 1.8 cobinamide adenolsyltransferase compare
HSERO_RS11995 +0.6 1.8 universal stress protein compare
HSERO_RS02780 +0.6 1.0 hypothetical protein compare
HSERO_RS04545 +0.6 1.5 integrase compare
HSERO_RS16400 +0.6 3.3 tryptophanyl-tRNA synthetase compare
HSERO_RS20595 +0.6 2.0 branched-chain amino acid ABC transporter substrate-binding protein compare
HSERO_RS11490 +0.6 3.1 D-ribose ABC transporter, permease component RbsC (from data) compare
HSERO_RS10730 +0.6 1.0 hypothetical protein compare
HSERO_RS04205 +0.6 2.1 membrane protein compare
HSERO_RS14005 +0.6 1.6 carboxylesterase compare
HSERO_RS02795 +0.6 1.1 alcohol dehydrogenase compare
HSERO_RS16910 +0.6 1.9 hypothetical protein compare
HSERO_RS13755 +0.6 2.2 hypothetical protein compare
HSERO_RS21395 +0.6 3.3 histone acetyltransferase compare
HSERO_RS03325 +0.6 1.5 hypothetical protein compare
HSERO_RS01785 +0.6 1.0 hypothetical protein compare
HSERO_RS07160 +0.6 2.3 phospho-2-dehydro-3-deoxyheptonate aldolase compare
HSERO_RS04845 +0.6 2.5 ABC transporter compare
HSERO_RS12465 +0.6 1.6 histidine kinase compare
HSERO_RS17905 +0.6 3.1 tRNA-dihydrouridine synthase A compare
HSERO_RS09760 +0.6 2.3 hypothetical protein compare
HSERO_RS09775 +0.6 0.6 cobalamin synthase compare
HSERO_RS08095 +0.6 2.1 ABC transporter substrate-binding protein compare
HSERO_RS05430 +0.6 2.2 NADPH:quinone reductase compare
HSERO_RS15900 +0.6 1.1 hypothetical protein compare
HSERO_RS05225 +0.6 1.3 L-arabinolactonase (EC 3.1.1.15) (from data) compare
HSERO_RS22415 +0.6 1.7 hypothetical protein compare
HSERO_RS09570 +0.6 1.4 Fe-S oxidoreductase compare
HSERO_RS11200 +0.6 2.0 peptidyl-prolyl cis-trans isomerase compare
HSERO_RS18015 +0.6 1.1 transcriptional regulator compare
HSERO_RS13360 +0.6 2.2 phosphoglucomutase compare
HSERO_RS11740 +0.6 2.1 esterase compare
HSERO_RS16045 +0.6 1.3 cytochrome oxidase compare
HSERO_RS19405 +0.6 1.8 enoyl-CoA hydratase compare
HSERO_RS11090 +0.6 2.4 phosphoribosylglycinamide formyltransferase compare
HSERO_RS11240 +0.6 1.5 mannosyltransferase compare
HSERO_RS05110 +0.6 1.2 RbsD or FucU transport protein compare


Specific Phenotypes

For 10 genes in this experiment

For stress Cobalt chloride hexahydrate in Herbaspirillum seropedicae SmR1

For stress Cobalt chloride hexahydrate across organisms