Experiment set2IT061 for Sinorhizobium meliloti 1021

Compare to:

LB, pH6

200 most detrimental genes:

  gene name fitness t score description  
SMc02367 +9.5 68.0 sensor histidine kinase transmembrane protein compare
SMc02366 +9.4 83.3 transcriptional regulator compare
SMc00067 +9.4 63.5 outer-membranne lipoprotein compare
SMc02365 +7.9 14.8 protease precursor protein compare
SMc02434 +7.6 8.4 hypothetical protein compare
SMc04454 +7.5 33.6 ABC transporter ATP-binding protein compare
SMc00150 +7.1 65.9 hypothetical protein compare
SMc04094 +6.7 27.8 hypothetical protein compare
SMc02112 +6.1 32.6 hypothetical protein compare
SMc03996 +5.8 22.5 thiamine-phosphate pyrophosphorylase compare
SMc02714 +5.5 16.9 hypothetical protein compare
SMc02641 +5.5 31.5 UDP-glucose 6-dehydrogenase compare
SMc01769 +5.5 44.4 hypothetical protein compare
SMc00194 +5.4 23.7 hypothetical protein compare
SMc02713 +5.4 17.5 RNA polymerase sigma-E factor (sigma-24) protein compare
SMc02640 +5.3 21.4 UDP-glucuronic acid epimerase compare
SMc01858 +5.0 12.9 S-adenosyl-methyltransferase MraW compare
SMc00355 +4.4 23.2 hypothetical protein compare
SMc00815 +4.4 10.5 inosine 5'-monophosphate dehydrogenase compare
SMc00427 +4.2 10.9 peptide chain release factor RF-3 protein compare
SMc01454 +4.1 29.2 hypothetical protein compare
SMc02636 +4.0 17.3 hypothetical protein compare
SMc02140 +3.9 9.5 phosphate regulon transcriptional regulatory protein compare
SMc00513 +3.8 20.2 amino acid-binding periplasmic protein compare
SMc03900 +3.8 31.3 cyclic beta-1,2-glucan ABc transporter compare
SM_b21491 +3.8 25.5 hypothetical protein compare
SMc02435 +3.7 11.6 methyltransferase compare
SMc04382 +3.7 28.9 beta-(1,2)-glucan production associated transmembrane protein compare
SMc02229 +3.5 22.7 acyl-CoA dehydrogenase compare
SMc02147 +3.3 11.8 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02058 +3.2 9.9 YAJC protein compare
SMc00622 +3.2 21.8 ribonuclease D protein compare
SMc03069 +3.2 11.2 6-phosphogluconolactonase compare
SM_b20613 +3.2 21.3 C4-dicarboxylate transport transcriptional regulator compare
SMc03969 +3.2 21.4 hypothetical protein compare
SMc02978 +2.9 12.3 hypothetical protein compare
SMc00522 +2.9 8.1 ATP-dependent RNA helicase compare
SM_b20509 +2.8 5.8 transcriptional regulator compare
SMc03935 +2.8 12.0 hypothetical protein compare
SMc02141 +2.7 5.5 phosphate transporter PhoU compare
SMc01221 +2.6 15.5 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc00070 +2.6 9.1 signal peptide protein compare
SMc03111 +2.6 15.2 mannose 6-phosphate isomerase (EC 5.3.1.8) (from data) compare
SMc01099 +2.5 9.0 tRNA pseudouridine synthase A compare
SMc01698 +2.5 14.5 oxidoreductase compare
SMc01220 +2.5 11.5 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc02659 +2.5 10.7 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein compare
SMc00174 +2.4 16.9 hypothetical protein compare
SMc01622 +2.4 9.3 oxidoreductase compare
SMc00175 +2.4 13.2 ABC transporter ATP-binding protein compare
SMc00176 +2.3 11.5 hypothetical protein compare
SMc00320 +2.2 4.0 ribosome-binding factor A compare
SMc03826 +2.2 6.1 argininosuccinate synthase compare
SMc00458 +2.2 17.2 transcriptional regulator compare
SMc00838 +2.2 14.2 hypothetical protein compare
SMc03855 +2.2 6.1 hypothetical protein compare
SMc01024 +2.1 4.1 preprotein translocase subunit SecG compare
SMc00177 +2.1 12.7 hypothetical protein compare
SM_b20312 +2.0 13.6 dihydroxyacetone kinase compare
SM_b20948 +2.0 2.7 glucosyltransferase compare
SMc00450 +2.0 4.2 protoheme IX farnesyltransferase compare
SMc03123 +2.0 15.6 transcriptional regulator compare
SMc02799 +1.9 2.5 16S rRNA methyltransferase GidB compare
SMc01441 +1.9 7.4 membrane bound protease compare
SMc00877 +1.9 14.9 transcriptional regulator compare
SMc00555 +1.9 3.5 colicin V production transmembrane protein compare
SMa1256 +1.8 1.8 hypothetical protein compare
SMc02142 +1.8 3.7 phosphate transporter ATP-binding protein compare
SMc01093 +1.8 1.7 esterase compare
SMc01929 +1.8 5.3 hypothetical protein compare
SMc00349 +1.8 11.8 GTP-binding protein LepA compare
SMc01222 +1.8 6.3 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc04001 +1.7 2.2 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc01440 +1.7 5.8 hydrolase serine protease transmembrane protein compare
SMc02639 +1.7 4.6 transcriptional regulator compare
SM_b21397 +1.7 1.4 hypothetical protein compare
SMc00495 +1.7 4.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc04043 +1.7 9.2 hypothetical protein compare
SMc01907 +1.7 12.9 hypothetical protein compare
SM_b20261 +1.6 1.3 malate dehydrogenase compare
SMc00726 +1.6 1.5 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc02373 +1.6 2.8 hypothetical protein compare
SMc00361 +1.5 4.7 hypothetical protein compare
SM_b21002 +1.5 7.0 methionine aminopeptidase compare
SMc02460 +1.5 8.3 hypothetical protein compare
SMc02864 +1.5 1.0 molybdopterin biosynthesis protein MoeB compare
SMc02055 +1.5 2.3 phytoene synthase compare
SMc00789 +1.5 5.6 peptide ABC transporter ATP-binding protein compare
SM_b21487 +1.5 8.8 cytochrome o ubiquinol oxidase subunit II compare
SMc02384 +1.5 7.3 glycosyltransferase transmembrane protein compare
SMa0222 +1.4 1.7 GntR family transcriptional regulator compare
SMc00061 +1.4 4.4 hypothetical protein compare
SMc01223 +1.4 3.0 transcriptional regulator compare
SM_b21046 +1.4 2.0 transposase of insertion sequence ISRm10-1, orfB C-terminus protein compare
SM_b20043 +1.4 7.1 hypothetical protein compare
SMc00788 +1.4 4.2 peptide ABC transporter permease compare
SMc04262 +1.4 1.1 6-phosphogluconate dehydrogenase compare
SMc02695 +1.4 7.7 GTP-dependent nucleic acid-binding protein EngD compare
SMc04224 +1.3 1.6 hypothetical protein compare
SM_b21102 +1.3 7.5 transcriptional regulator compare
SMc00786 +1.3 9.9 periplasmic dipeptide-binding protein compare
SMc00787 +1.3 6.9 peptide ABC transporter permease compare
SMc00143 +1.3 2.7 molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
SMc01857 +1.3 3.8 cell division protein MraZ compare
SMc01800 +1.3 2.7 cytochrome C oxidase assembly transmembrane protein compare
SMc01852 +1.3 7.2 pyrophosphate--fructose-6-phosphate 1-phosphotransferase compare
SM_b21488 +1.3 8.4 cytochrome o ubiquinol oxidase subunit I compare
SMc01203 +1.3 2.6 hypothetical protein compare
SMc00010 +1.3 3.6 cytochrome C oxidase polypeptide I transmembrane protein compare
SMc02565 +1.3 4.6 hypothetical protein compare
SMc02558 +1.3 4.4 hypothetical protein compare
SM_b20313 +1.3 3.9 glycerone kinase compare
SMc03880 +1.2 7.7 hypothetical protein compare
SMc00648 +1.2 4.6 hypothetical protein compare
SMc02051 +1.2 2.0 hypothetical protein compare
SM_b20815 +1.2 1.4 outer membrane protein assembly protein compare
SMc01495 +1.2 2.9 transcriptional regulator compare
SMc02407 +1.2 6.3 hypothetical protein compare
SMc02826 +1.2 2.7 transcriptional regulator compare
SMc00618 +1.2 7.7 polyphosphate kinase compare
SMc01587 +1.2 2.8 hypothetical protein compare
SMa1700 +1.1 2.1 hypothetical protein compare
SMc02057 +1.1 5.2 preprotein translocase subunit SecD/SecF compare
SMc01202 +1.1 6.7 lipoprotein compare
SMc02694 +1.1 1.5 ATP-dependent Clp protease adaptor compare
SMc00790 +1.1 6.7 peptide ABC transporter ATP-binding protein compare
SMc00588 +1.1 1.4 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
SMc03930 +1.1 1.6 sarcosine oxidase subunit gamma compare
SMc01504 +1.1 4.6 two-component response regulator compare
SMa1002 +1.1 1.7 hypothetical protein compare
SMc05015 +1.1 1.6 recombinase compare
SMc01427 +1.0 1.7 hypothetical protein compare
SMc03068 +1.0 3.7 phosphogluconate dehydratase compare
SMc00945 +1.0 3.4 xanthine-guanine phosphoribosyltransferase compare
SMc03016 +1.0 3.7 transcriptional regulator compare
SM_b20751 +1.0 1.1 3-hydroxyisobutyrate dehydrogenase compare
SMc02895 +1.0 3.8 hypothetical protein compare
SMc04441 +1.0 2.0 hypothetical protein compare
SMa1045 +1.0 3.2 hypothetical protein compare
SMc04298 +1.0 1.1 hypothetical protein compare
SMc04348 +1.0 2.9 transcriptional regulator compare
SM_b21163 +1.0 4.0 Urocanate hydratase (EC 4.2.1.49) (from data) compare
SM_b21489 +1.0 2.2 cytochrome O ubiquinol oxidase subunit III compare
SMc02234 +1.0 2.2 hypothetical protein compare
SMc04330 +1.0 2.1 trimethylamine methyltransferase compare
SM_b20314 +1.0 4.6 glycerone kinase compare
SM_b20954 +1.0 5.9 succinyltransferase compare
SMc05009 +1.0 1.7 nodulation protein NolR compare
SMc01916 +1.0 1.4 signal peptide protein compare
SMc01124 +1.0 4.9 PII uridylyl-transferase compare
SM_b20684 +1.0 7.3 hypothetical protein compare
SMc01139 +1.0 3.4 RNA polymerase factor sigma-54 compare
SM_b20611 +0.9 5.8 C4-dicarboxylate transporter DctA compare
SMc03279 +0.9 1.6 transposase number 2 for insertion sequence ISRM28 compare
SMc04327 +0.9 1.1 hypothetical protein compare
SMc01107 +0.9 4.7 hypothetical protein compare
SMc02561 +0.9 2.3 hypothetical protein compare
SMa0643 +0.9 1.7 transposase compare
SMc00656 +0.9 0.8 hypothetical protein compare
SM_b21111 +0.9 1.5 oxidoreductase, RED superfamily protein compare
SMc01842 +0.9 1.9 methyltransferase transcription regulator protein compare
SMc04246 +0.9 1.6 transmembrane signal peptide protein compare
SMc02173 +0.9 1.4 hypothetical protein compare
SMc00329 +0.9 1.8 iron response regulator protein compare
SMc04381 +0.9 5.9 hypothetical protein compare
SM_b20562 +0.9 5.7 hypothetical protein compare
SM_b20219 +0.9 1.9 response regulator protein compare
SM_b20998 +0.9 5.7 hypothetical protein compare
SMc00134 +0.9 4.8 hypothetical protein compare
SMa0545 +0.9 2.5 hypothetical protein compare
SMc02765 +0.9 6.7 tryptophan synthase subunit alpha compare
SMa0017 +0.9 1.5 hypothetical protein compare
SMc04121 +0.9 2.2 uracil phosphoribosyltransferase compare
SMc02757 +0.9 2.8 hypothetical protein compare
SMc00794 +0.9 4.6 two-component response regulator compare
SMc04166 +0.9 1.1 hypothetical protein compare
SMa1210 +0.9 1.6 nitrogen fixation protein FixH compare
SM_b21192 +0.9 6.4 fructose-1,6-bisphosphate aldolase compare
SMc03833 +0.9 2.4 hypothetical protein compare
SMc03993 +0.9 4.2 hypothetical protein compare
SM_b20612 +0.8 3.7 C4-dicarboxylate transport sensor protein compare
SMc00878 +0.8 6.0 transcriptional regulator compare
SMc00129 +0.8 4.1 sensor histidine kinase compare
SM_b21372 +0.8 5.2 LacI family transcriptional regulator compare
SMc00482 +0.8 4.3 hypothetical protein compare
SMc02904 +0.8 1.6 hypothetical protein compare
SMc04209 +0.8 1.5 hypothetical protein compare
SMa1593 +0.8 1.4 oxidoreductase, fragment compare
SMc02137 +0.8 2.8 ornithine carbamoyltransferase compare
SMc03824 +0.8 2.0 transcriptional regulator compare
SMc01244 +0.8 2.1 tRNA-Ala compare
SMc00511 +0.8 3.7 D-ribulose-5-phosphate 3-epimerase compare
SMc02517 +0.8 2.2 ABC transporter permease compare
SM_b20293 +0.8 1.0 hypothetical protein compare
SMc02520 +0.8 5.8 glycerol-3-phosphate dehydrogenase (EC 1.1.5.3) (from data) compare
SMc01716 +0.8 3.5 sensor histidine kinase transmembrane protein compare
SMa1894 +0.8 1.4 methionine sulfoxide reductase B compare
SM_b21100 +0.8 2.4 polysaccharide deacetylase compare
SM_b21454 +0.8 1.6 hypothetical protein compare
SM_b20114 +0.8 1.3 hypothetical protein compare


Specific Phenotypes

For 9 genes in this experiment