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Experiment set2IT060 for
Sinorhizobium meliloti 1021
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200 most important genes:
gene
name
fitness
t score
description
SMc02850
-5.3
-3.6
DNA polymerase I
compare
SMc01845
-3.9
-3.0
transglycosylase transmembrane protein
compare
SMc02140
-3.8
-1.6
phosphate regulon transcriptional regulatory protein
compare
SMc02909
-3.7
-3.2
transglycosylase transmembrane protein
compare
SMc00334
-3.4
-2.6
cytidylate kinase
compare
SMc01880
-3.3
-3.2
pantoate--beta-alanine ligase
compare
SMc02144
-3.3
-5.3
phosphate ABC transporter permease
compare
SMc02147
-3.0
-9.3
phosphate regulon sensor histidine kinase transmembrane protein
compare
SMc00726
-3.0
-0.9
thiol:disulfide interchange redox-active center transmembrane protein
compare
SMc02234
-2.8
-3.6
hypothetical protein
compare
SMc03850
-2.8
-1.8
heme exporter D (cytochrome C-type biogenesis protein) transmembrane
compare
SMc02778
-2.7
-1.2
hydroxyacid aldolase
compare
SMc00914
-2.6
-5.7
oxidoreductase
compare
SMc00963
-2.6
-5.0
hypothetical protein
compare
SMc01364
-2.5
-1.4
DNA topoisomerase I
compare
SMc02115
-2.4
-1.1
hypothetical protein
compare
SMc03967
-2.4
-1.5
Holliday junction resolvase
compare
SMc01147
-2.4
-3.5
coproporphyrinogen III oxidase
compare
SMc02484
-2.4
-8.0
amino acid efflux transmembrane protein
compare
SMc04296
-2.4
-1.0
cell division protein FtsZ
compare
SMc02833
-2.3
-2.7
penicillin-insensitive murein endopeptidase
compare
SMc04121
-2.3
-2.1
uracil phosphoribosyltransferase
compare
SMc02510
-2.2
-1.0
ferric uptake regulation protein
compare
SMc01881
-2.2
-4.3
3-methyl-2-oxobutanoate hydroxymethyltransferase
compare
SMc02142
-2.2
-4.9
phosphate transporter ATP-binding protein
compare
SMc00580
-2.1
-4.2
4-hydroxythreonine-4-phosphate dehydrogenase
compare
SMc02867
-2.1
-4.0
multidrug-efflux system transmembrane protein
compare
SMc01579
-2.1
-1.3
hypothetical protein
compare
SMc02232
-2.1
-3.9
hypothetical protein
compare
SMc00492
-2.0
-1.1
hypothetical protein
compare
SMc03182
-1.9
-6.5
pH adaptation potassium efflux system E transmembrane protein
compare
SMc00579
-1.9
-6.7
dimethyladenosine transferase
compare
SMc02143
-1.9
-3.7
phosphate ABC transporter permease
compare
SMc04330
-1.8
-2.5
trimethylamine methyltransferase
compare
SMc03180
-1.8
-5.4
monovalent cation/H+ antiporter subunit C
compare
SMc01342
-1.7
-5.2
hypothetical protein
compare
SMc03878
-1.7
-2.8
acetoacetyl-CoA reductase
compare
SMc00067
-1.7
-7.0
outer-membranne lipoprotein
compare
SMc04024
-1.7
-5.3
membrane-bound lytic murein transglycosylase
compare
SMc01208
-1.7
-2.3
peptidyl-prolyl cis-trans isomerase B protein
compare
SMc02753
-1.7
-1.4
PTS system transporter subunit IIA
compare
SMc03763
-1.7
-3.1
cytosine-specific methyltransferase
compare
SMc02435
-1.7
-2.3
methyltransferase
compare
SMc02145
-1.6
-1.0
signal peptide protein
compare
SMc01361
-1.6
-4.6
dihydroorotase
compare
SMc02077
-1.6
-3.2
exodeoxyribonuclease III protein
compare
SMc00556
-1.6
-4.4
DNA repair protein RadA
compare
SMc03773
-1.6
-5.4
hypothetical protein
compare
SMc02114
-1.6
-3.6
hypothetical protein
compare
SMc01012
-1.5
-1.6
hypothetical protein
compare
SMc02683
-1.5
-1.9
hypothetical protein
compare
SM
_b20452
-1.5
-3.4
hypothetical protein
compare
SMa0789
-1.5
-3.6
GntR family transcriptional regulator
compare
SM
_b21524
-1.5
-2.2
septum formation inhibitor
compare
SMc01877
-1.5
-5.9
DNA repair protein
compare
SMc03181
-1.5
-5.9
monovalent cation/H+ antiporter subunit D
compare
SMc00496
-1.4
-1.3
hypothetical protein
compare
SMc02868
-1.4
-4.1
multidrug efflux system protein
compare
SMc00331
-1.4
-2.8
hypothetical protein
compare
SMc02582
-1.4
-3.5
hypothetical protein
compare
SMc01716
-1.3
-5.3
sensor histidine kinase transmembrane protein
compare
SMc01187
-1.3
-1.8
rare lipoprotein A
compare
SMc03100
-1.3
-1.7
hypothetical protein
compare
SMc02451
-1.3
-1.2
hypothetical protein
compare
SMc02856
-1.3
-5.5
penicillin-binding protein
compare
SMc00856
-1.3
-1.1
hypothetical protein
compare
SMc00691
-1.3
-3.0
site-specific tyrosine recombinase XerD
compare
SM
_b20413
-1.3
-1.1
hypothetical protein
compare
SMc00760
-1.3
-4.3
recombinase A
compare
SMc02719
-1.3
-0.9
transposase
compare
SM
_b20758
-1.3
-1.0
ArsR family transcriptional regulator
compare
SMc02149
-1.3
-1.6
hypothetical protein
compare
SMc02102
-1.2
-3.5
hypothetical protein
compare
SMc01700
-1.2
-3.9
peptidyl-prolyl cis-trans isomerase A
compare
SMc02641
-1.2
-4.3
UDP-glucose 6-dehydrogenase
compare
SMc03179
-1.2
-7.3
monovalent cation/H+ antiporter subunit A
compare
SMc02886
-1.2
-1.6
signal peptide protein
compare
SMc02338
-1.2
-1.7
periplasmic binding ABC transporter protein
compare
SMc02071
-1.2
-3.4
hydrolase glycosidase
compare
SMc01850
-1.2
-1.7
hypothetical protein
compare
SMc03183
-1.2
-2.9
monovalent cation/H+ antiporter subunit F
compare
SMc01577
-1.2
-1.5
hypothetical protein
compare
SMc00976
-1.2
-1.1
enoyl-CoA hydratase
compare
SMc01619
-1.2
-2.0
hypothetical protein
compare
SMc00557
-1.1
-3.3
alanine racemase
compare
SMc01929
-1.1
-2.2
hypothetical protein
compare
SMc03993
-1.1
-2.3
hypothetical protein
compare
SMc03774
-1.1
-1.8
hypothetical protein
compare
SMc04233
-1.1
-2.5
hypothetical protein
compare
SMc01438
-1.1
-3.0
protease precursor signal peptide protein
compare
SMc00987
-1.1
-2.0
hypothetical protein
compare
SMc00088
-1.1
-1.3
hypothetical protein
compare
SMc00619
-1.1
-1.3
hypothetical protein
compare
SMc01461
-1.1
-4.0
DNA helicase II protein
compare
SMc03184
-1.1
-0.9
PH adaptation potassium efflux system G transmembrane protein
compare
SMc01259
-1.1
-1.6
hypothetical protein
compare
SM
_b21096
-1.1
-1.0
amino acid transporter ABC transporter ATP-binding protein
compare
SMc01220
-1.1
-3.1
lipopolysaccharide core biosynthesis glycosyl transferase
compare
SMc03229
-1.1
-1.1
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
compare
SMc00296
-1.1
-6.3
POLY3-hydroxybutyrate polymerase
compare
SMc03128
-1.1
-3.4
ABC transporter permease
compare
SMa2299
-1.1
-1.4
hypothetical protein
compare
SMc00812
-1.1
-2.3
hypothetical protein
compare
SM
_b20509
-1.0
-2.4
transcriptional regulator
compare
SMc04090
-1.0
-1.7
sun protein
compare
SMc04391
-1.0
-1.1
3-ketoacyl-ACP reductase
compare
SMc01568
-1.0
-1.0
hypothetical protein
compare
SMc00025
-1.0
-5.7
pyruvate phosphate dikinase
compare
SMa0738
-1.0
-2.0
CspA6 cold shock protein transcriptional regulator
compare
SMc04231
-1.0
-5.9
excinuclease ABC subunit B
compare
SMc03140
-1.0
-2.3
transcriptional regulator
compare
SMa1239
-1.0
-1.5
NapD component of periplasmic nitrate reductase
compare
SM
_b20774
-1.0
-1.8
hypothetical protein
compare
SMc00451
-1.0
-4.2
processing protease
compare
SMc01183
-1.0
-1.3
LexA repressor
compare
SM
_b20889
-1.0
-3.0
hypothetical protein
compare
SMc02758
-1.0
-3.8
nucleotidyl transferase
compare
SMc03051
-1.0
-2.6
flagellar biosynthesis repressor FlbT
compare
SMc01853
-0.9
-2.5
hypothetical protein
compare
SMa0112
-0.9
-1.9
hypothetical protein
compare
SMc02280
-0.9
-1.3
hypothetical protein
compare
SMc02634
-0.9
-6.3
hypothetical protein
compare
SM
_b21523
-0.9
-1.8
cell division inhibitor protein
compare
SMc00396
-0.9
-1.7
hypothetical protein
compare
SMc02505
-0.9
-1.2
hypothetical protein
compare
SMc00353
-0.9
-1.4
transmembrane protein
compare
SMa5031
-0.9
-1.2
hypothetical protein
compare
SM
_b20370
-0.9
-2.4
ATP-binding transport protein
compare
SMc04169
-0.9
-5.7
transcriptional regulator
compare
SMc00228
-0.9
-6.1
ATP-dependent DNA helicase RecG
compare
SMc00602
-0.9
-2.9
excinuclease ABC subunit C
compare
SMc02569
-0.9
-2.4
imidazole glycerol phosphate synthase subunit HisF
compare
SMa0050
-0.9
-2.2
hypothetical protein
compare
SMc02866
-0.9
-2.5
transcriptional regulator
compare
SM
_b20896
-0.9
-3.0
LysR family transcriptional regulator
compare
SMc04340
-0.9
-5.6
oxidoreductase
compare
SMc02978
-0.9
-2.4
hypothetical protein
compare
SMc00103
-0.9
-4.3
alpha-halocarboxylic acid dehalogenase
compare
SMa1118
-0.9
-1.2
HspC2 heat shock protein
compare
SM
_b20123
-0.9
-2.1
transcriptional regulator
compare
SMc02576
-0.9
-1.2
acetyltransferase
compare
SM
_b20602
-0.9
-2.6
branched-chain amino acid ABC transporter ATP-binding protein
compare
SMc04388
-0.9
-4.1
beta alanine--pyruvate transaminase
compare
SM
_b20595
-0.9
-3.3
cell division protein FtsK
compare
SMc02724
-0.8
-2.0
hypothetical protein
compare
SMc01039
-0.8
-1.6
hypothetical protein
compare
SM
_b20450
-0.8
-5.6
regulatory protein
compare
SMc00527
-0.8
-6.0
anhydro-N-acetylmuramic acid kinase
compare
SMc01360
-0.8
-1.7
aspartate carbamoyltransferase catalytic subunit
compare
SMa0905
-0.8
-0.9
hypothetical protein
compare
SM
_b20987
-0.8
-1.3
siroheme synthase
compare
SMc00378
-0.8
-1.5
exodeoxyribonuclease VII large subunit
compare
SMc02172
-0.8
-3.6
transcriptional regulator
compare
SMc03868
-0.8
-2.4
hypothetical protein
compare
SMc00665
-0.8
-1.4
hypothetical protein
compare
SMa0360
-0.8
-2.3
transposase
compare
SMc00104
-0.8
-2.6
hypothetical protein
compare
SMc01709
-0.8
-2.3
signal peptide protein
compare
SMc01457
-0.8
-4.9
transport transmembrane protein
compare
SMc00948
-0.8
-4.5
glutamine synthetase
compare
SMc01280
-0.8
-1.2
protease
compare
SMc03060
-0.8
-5.5
transcriptional regulator
compare
SMc00876
-0.8
-3.2
ATP-binding MRP protein
compare
SM
_b20258
-0.8
-2.2
transcriptional regulator
compare
SMc00675
-0.8
-5.8
hypothetical protein
compare
SM
_b20547
-0.8
-1.1
hypothetical protein
compare
SMc03979
-0.8
-1.2
glyceraldehyde-3-phosphate dehydrogenase
compare
SMc01651
-0.8
-1.8
transcriptional regulator
compare
SM
_b20998
-0.8
-4.4
hypothetical protein
compare
SMc02979
-0.8
-2.6
hypothetical protein
compare
SMc03245
-0.8
-3.2
amidase
compare
SMc04168
-0.8
-2.4
hypothetical protein
compare
SM
_b21218
-0.8
-1.6
glucosamine-6-phosphate deaminase, isomerizing (EC 3.5.99.6)
(from data)
compare
SMa1770
-0.8
-0.8
hypothetical protein
compare
SMc03124
-0.8
-2.2
periplasmic binding ABC transporter protein
compare
SMc00970
-0.8
-1.5
exodeoxyribonuclease VII small subunit
compare
SMc03227
-0.8
-2.3
hypothetical protein
compare
SMc00255
-0.7
-4.0
hypothetical protein
compare
SM
_b20447
-0.7
-4.4
hypothetical protein
compare
SMc02362
-0.7
-1.7
cytochrome c-type biogenesis protein CcmE
compare
SMc01517
-0.7
-1.4
hypothetical protein
compare
SM
_b20822
-0.7
-3.7
cell surface polysaccharide export ABC-2 transporter permease, close relative to wzm1Y20833
compare
SM
_b20563
-0.7
-1.4
hypothetical protein
compare
SM
_b20273
-0.7
-2.0
hypothetical protein
compare
SMc04389
-0.7
-1.5
hydroxypyruvate reductase
compare
SMc02319
-0.7
-1.9
hypothetical protein
compare
SMa0323
-0.7
-3.2
hypothetical protein
compare
SMa1153
-0.7
-1.7
hypothetical protein
compare
SMc02658
-0.7
-1.3
hypothetical protein
compare
SM
_b20901
-0.7
-4.0
transcriptional regulator
compare
SMc01347
-0.7
-1.8
hypothetical protein
compare
SMc03942
-0.7
-5.1
hypothetical protein
compare
SMc02495
-0.7
-0.8
translaldolase
compare
SMa1576
-0.7
-2.4
CpaB2 pilus assembly protein
compare
SMc00689
-0.7
-2.8
lipoprotein
compare
SMc02061
-0.7
-4.2
biotin-regulated protein
compare
SMa0093
-0.7
-1.4
Branched-chain amino acid aminotransferase
compare
SMc00286
-0.7
-1.1
hemolysin-type calcium-binding protein
compare
SMa0265
-0.7
-1.4
dehydrogenase
compare
SMa1442
-0.7
-2.6
GntR family transcriptional regulator
compare
Specific Phenotypes
For 12 genes in this experiment