Experiment set2IT058 for Methanococcus maripaludis JJ

200 most detrimental genes:

gene	name	fitness	t score	description
MMJJ_RS08725		+1.3	10.0	flippase
MMJJ_RS04215		+1.3	11.7	DMT family transporter
MMJJ_RS08720		+1.3	10.7	UDP-glucose/GDP-mannose dehydrogenase family protein
MMJJ_RS04720		+1.1	1.4	IMP dehydrogenase
MMJJ_RS03205		+1.0	5.6	metallophosphoesterase
MMJJ_RS00415		+0.9	4.7	DedA family protein
MMJJ_RS08750		+0.9	7.0	glycosyltransferase
MMJJ_RS06975		+0.7	2.3	protein translocase SEC61 complex subunit gamma
MMJJ_RS09265		+0.7	2.5	hypothetical protein
MMJJ_RS01210		+0.7	2.0	hypothetical protein
MMJJ_RS06755		+0.7	5.8	diadenylate cyclase
MMJJ_RS09325		+0.7	4.1	hypothetical protein
MMJJ_RS06130		+0.7	2.8	hypothetical protein
MMJJ_RS06105		+0.7	4.5	DUF99 family protein
MMJJ_RS03185		+0.7	1.1	alanine--tRNA ligase
MMJJ_RS06585		+0.6	4.6	alanine racemase
MMJJ_RS08730		+0.6	5.1	glycosyltransferase family 4 protein
MMJJ_RS06205		+0.6	4.3	EamA family transporter
MMJJ_RS06430		+0.6	3.5	haloacid dehalogenase
MMJJ_RS06210		+0.6	4.1	hypothetical protein
MMJJ_RS01010		+0.6	5.8	right-handed parallel beta-helix repeat-containing protein
MMJJ_RS06135		+0.6	4.4	50S ribosomal protein L11 methyltransferase
MMJJ_RS06470		+0.6	3.6	tripartite tricarboxylate transporter permease
MMJJ_RS06505		+0.6	2.1	prephenate dehydratase
MMJJ_RS08760		+0.6	3.9	glycosyltransferase family 9 protein
MMJJ_RS06275		+0.6	3.1	hypothetical protein
MMJJ_RS06445		+0.5	4.6	hypothetical protein
MMJJ_RS06495		+0.5	1.9	hypothetical protein
MMJJ_RS05695		+0.5	3.8	class III signal peptide-containing protein
MMJJ_RS00480		+0.5	4.3	flippase
MMJJ_RS07610		+0.5	3.2	DUF2119 domain-containing protein
MMJJ_RS06465		+0.5	3.2	hypothetical protein
MMJJ_RS06440		+0.5	3.3	DUF4870 domain-containing protein
MMJJ_RS07030		+0.5	4.3	hypothetical protein
MMJJ_RS06450		+0.5	3.6	DUF3343 domain-containing protein
MMJJ_RS08040		+0.5	3.9	NAD(P)/FAD-dependent oxidoreductase
MMJJ_RS06555		+0.5	3.9	ATP-binding cassette domain-containing protein
MMJJ_RS06720		+0.5	3.7	mechanosensitive ion channel family protein
MMJJ_RS05870		+0.5	1.5	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMJJ_RS06460		+0.5	3.4	cytochrome c
MMJJ_RS09365		+0.5	1.7	hypothetical protein
MMJJ_RS05700		+0.5	3.2	metallophosphoesterase
MMJJ_RS09390		+0.5	1.3	hypothetical protein
MMJJ_RS03370		+0.5	1.7	hypothetical protein
MMJJ_RS07420		+0.5	3.0	protease complex subunit PrcB family protein
MMJJ_RS06120		+0.5	3.0	DUF4013 domain-containing protein
MMJJ_RS08380		+0.5	2.1	hypothetical protein
MMJJ_RS06160		+0.5	3.2	stage II sporulation protein M
MMJJ_RS06770		+0.5	3.8	hypothetical protein
MMJJ_RS07740		+0.4	2.8	DUF2334 domain-containing protein
MMJJ_RS07270		+0.4	3.0	ribonuclease HII
MMJJ_RS07210		+0.4	3.1	AmmeMemoRadiSam system protein B
MMJJ_RS06765		+0.4	3.6	hypothetical protein
MMJJ_RS05530		+0.4	2.1	roadblock/LC7 domain-containing protein
MMJJ_RS06580		+0.4	3.3	alanine dehydrogenase
MMJJ_RS06455		+0.4	3.0	YeeE/YedE family protein
MMJJ_RS06550		+0.4	3.1	ABC transporter permease
MMJJ_RS01615		+0.4	2.0	MoaD/ThiS family protein
MMJJ_RS07825		+0.4	1.4	YciI family protein
MMJJ_RS06190		+0.4	3.2	7-cyano-7-deazaguanine synthase
MMJJ_RS01125		+0.4	2.0	hypothetical protein
MMJJ_RS06115		+0.4	3.1	pyruvate kinase
MMJJ_RS08715		+0.4	2.1	NAD-dependent epimerase/dehydratase family protein
MMJJ_RS05605		+0.4	2.0	hypothetical protein
MMJJ_RS09355		+0.4	2.0	hypothetical protein
MMJJ_RS06810		+0.4	3.1	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha
MMJJ_RS05915		+0.4	1.3	multiprotein bridging factor aMBF1
MMJJ_RS06045		+0.4	2.9	hypothetical protein
MMJJ_RS04415		+0.4	1.1	hypothetical protein
MMJJ_RS07025		+0.4	2.0	tRNA (cytidine(56)-2'-O)-methyltransferase
MMJJ_RS07620		+0.4	2.7	class I SAM-dependent rRNA methyltransferase
MMJJ_RS05985		+0.4	2.4	ABC transporter substrate-binding protein
MMJJ_RS07915		+0.4	2.5	CBS domain-containing protein
MMJJ_RS04525		+0.4	1.4	hypothetical protein
MMJJ_RS06680		+0.4	2.3	DUF366 family protein
MMJJ_RS06235		+0.4	3.2	IGHMBP2 family helicase
MMJJ_RS06710		+0.4	2.9	TldD/PmbA family protein
MMJJ_RS04245		+0.4	2.3	flavoprotein
MMJJ_RS06280		+0.4	2.6	hypothetical protein
MMJJ_RS06080		+0.4	2.8	serine/threonine protein kinase
MMJJ_RS01100		+0.4	0.7	helix-turn-helix domain-containing protein
MMJJ_RS06100		+0.4	2.7	rubrerythrin
MMJJ_RS07040		+0.4	0.4	preprotein translocase subunit SecY
MMJJ_RS07255		+0.4	3.1	hypothetical protein
MMJJ_RS05980		+0.4	2.0	DUF5400 domain-containing protein
MMJJ_RS07385		+0.4	2.5	ribosomal protein S18-alanine N-acetyltransferase
MMJJ_RS06285		+0.3	2.0	YchF/TatD family DNA exonuclease
MMJJ_RS02000		+0.3	1.4	AzlD domain-containing protein
MMJJ_RS06640		+0.3	2.5	YfcE family phosphodiesterase
MMJJ_RS08025		+0.3	1.2	hypothetical protein
MMJJ_RS09010		+0.3	1.4	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
MMJJ_RS01275		+0.3	1.9	4Fe-4S dicluster domain-containing protein
MMJJ_RS09405		+0.3	1.0	hypothetical protein
MMJJ_RS07450		+0.3	1.8	hypothetical protein
MMJJ_RS07495		+0.3	1.8	4Fe-4S binding protein
MMJJ_RS06960		+0.3	2.9	CAP domain-containing protein
MMJJ_RS06515		+0.3	2.4	ribonuclease III
MMJJ_RS05505		+0.3	3.0	hypothetical protein
MMJJ_RS05525		+0.3	1.6	GTP-binding protein
MMJJ_RS05400		+0.3	1.3	CoA-binding protein
MMJJ_RS09225		+0.3	1.6	hypothetical protein
MMJJ_RS05965		+0.3	2.6	MFS transporter
MMJJ_RS07635		+0.3	1.9	response regulator transcription factor
MMJJ_RS06520		+0.3	2.1	TldD/PmbA family protein
MMJJ_RS07690		+0.3	1.9	glycosyltransferase family 4 protein
MMJJ_RS09380		+0.3	0.8	hypothetical protein
MMJJ_RS04825		+0.3	2.5	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
MMJJ_RS03410		+0.3	0.9	hypothetical protein
MMJJ_RS08400		+0.3	1.4	CoB--CoM heterodisulfide reductase subunit C
MMJJ_RS05890		+0.3	2.2	molybdate ABC transporter substrate-binding protein
MMJJ_RS07665		+0.3	2.4	formate dehydrogenase subunit alpha
MMJJ_RS05250		+0.3	1.4	HDIG domain-containing protein
MMJJ_RS03285		+0.3	1.4	gamma-glutamylcyclotransferase
MMJJ_RS07500		+0.3	2.0	hypothetical protein
MMJJ_RS07650		+0.3	2.3	formate/nitrite transporter family protein
MMJJ_RS05290		+0.3	2.4	DUF4013 domain-containing protein
MMJJ_RS05925		+0.3	1.7	DUF2099 family protein
MMJJ_RS09235		+0.3	1.2	helix-turn-helix transcriptional regulator
MMJJ_RS05510		+0.3	1.5	archaellum operon transcriptional activator EarA family protein
MMJJ_RS01770		+0.3	1.2	TOBE domain-containing protein
MMJJ_RS08370		+0.3	1.1	hypothetical protein
MMJJ_RS01110		+0.3	1.0	hypothetical protein
MMJJ_RS06295		+0.3	1.4	DUF2096 family protein
MMJJ_RS07830		+0.3	2.0	DUF1786 domain-containing protein
MMJJ_RS08325		+0.3	0.4	glycosyltransferase family 2 protein
MMJJ_RS04480		+0.3	0.6	hypothetical protein
MMJJ_RS00420		+0.3	1.3	CBS domain-containing protein
MMJJ_RS04925		+0.3	1.9	cation:proton antiporter
MMJJ_RS06055		+0.3	1.6	S-methyl-5-thioribose-1-phosphate isomerase
MMJJ_RS07365		+0.2	1.9	CatB-related O-acetyltransferase
MMJJ_RS05335		+0.2	1.2	heavy metal-binding domain-containing protein
MMJJ_RS01285		+0.2	1.5	CopG family ribbon-helix-helix protein
MMJJ_RS07480		+0.2	1.9	FAD-dependent oxidoreductase
MMJJ_RS03715		+0.2	1.7	hypothetical protein
MMJJ_RS06745		+0.2	1.6	energy-coupling factor ABC transporter permease
MMJJ_RS08705		+0.2	1.4	AEC family transporter
MMJJ_RS06740		+0.2	1.3	energy-coupling factor ABC transporter substrate-binding protein
MMJJ_RS03850		+0.2	1.0	nucleoside-diphosphate kinase
MMJJ_RS09255		+0.2	0.8	hypothetical protein
MMJJ_RS05500		+0.2	2.1	hypothetical protein
MMJJ_RS03510		+0.2	1.6	acyl-CoA dehydratase activase
MMJJ_RS08830		+0.2	0.9	hypothetical protein
MMJJ_RS05195		+0.2	0.7	hypothetical protein
MMJJ_RS05875		+0.2	2.1	hypothetical protein
MMJJ_RS07640		+0.2	2.0	cache domain-containing protein
MMJJ_RS01205		+0.2	1.5	DNA adenine methylase
MMJJ_RS06075		+0.2	1.5	DNA-binding protein Alba
MMJJ_RS02885		+0.2	0.9	NifB/NifX family molybdenum-iron cluster-binding protein
MMJJ_RS07905		+0.2	1.4	DUF89 domain-containing protein
MMJJ_RS06685		+0.2	1.9	S-layer protein
MMJJ_RS06385		+0.2	1.2	hypothetical protein
MMJJ_RS05690		+0.2	2.0	hypothetical protein
MMJJ_RS06800		+0.2	1.1	prefoldin subunit alpha
MMJJ_RS05990		+0.2	1.3	phosphatase PAP2 family protein
MMJJ_RS01920		+0.2	1.7	phosphoglycerate mutase
MMJJ_RS07820		+0.2	1.7	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMJJ_RS01515		+0.2	0.9	DUF2178 domain-containing protein
MMJJ_RS01825		+0.2	0.8	DNA repair and recombination protein RadB
MMJJ_RS07910		+0.2	1.4	CBS domain-containing protein
MMJJ_RS09295		+0.2	0.2	hypothetical protein
MMJJ_RS07795		+0.2	1.2	cupin domain-containing protein
MMJJ_RS08515		+0.2	0.8	secondary thiamine-phosphate synthase enzyme YjbQ
MMJJ_RS05970		+0.2	0.9	MJ0307 family thioredoxin
MMJJ_RS00540		+0.2	1.2	hypothetical protein
MMJJ_RS05940		+0.2	1.5	HAD family hydrolase
MMJJ_RS00440		+0.2	1.5	selenide, water dikinase SelD
MMJJ_RS07920		+0.2	1.6	6-carboxytetrahydropterin synthase QueD
MMJJ_RS05880		+0.2	1.8	hypothetical protein
MMJJ_RS00840		+0.2	0.7	hypothetical protein
MMJJ_RS05240		+0.2	1.7	type II secretion system F family protein
MMJJ_RS07670		+0.2	1.7	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain
MMJJ_RS03425		+0.2	0.6	DUF2080 family transposase-associated protein
MMJJ_RS05235		+0.2	1.8	Flp pilus assembly complex ATPase component TadA
MMJJ_RS03955		+0.2	1.3	hypothetical protein
MMJJ_RS05955		+0.2	1.5	radical SAM protein
MMJJ_RS04165		+0.2	1.5	sodium:solute symporter
MMJJ_RS05410		+0.2	1.3	RecB-family nuclease
MMJJ_RS04055		+0.2	0.9	hypothetical protein
MMJJ_RS05365		+0.2	1.0	DUF2798 domain-containing protein
MMJJ_RS05600		+0.2	1.6	sodium:solute symporter family protein
MMJJ_RS08630		+0.2	1.0	signal recognition particle subunit SRP19/SEC65 family protein
MMJJ_RS09370		+0.2	0.4	heavy-metal-associated domain-containing protein
MMJJ_RS05030		+0.2	1.5	orotate phosphoribosyltransferase-like protein
MMJJ_RS07445		+0.2	1.3	RlmF-related methyltransferase
MMJJ_RS03520		+0.2	1.3	hypothetical protein
MMJJ_RS02860		+0.2	0.4	site-specific integrase
MMJJ_RS07400		+0.2	0.8	2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMJJ_RS08365		+0.2	0.7	DsrE family protein
MMJJ_RS00525		+0.2	0.5	Dabb family protein
MMJJ_RS05495		+0.2	1.2	MinD/ParA family protein
MMJJ_RS05730		+0.2	1.4	TIM barrel protein
MMJJ_RS07645		+0.2	1.1	selenium-binding protein
MMJJ_RS08690		+0.2	1.3	phosphate ABC transporter substrate-binding protein
MMJJ_RS05435		+0.2	1.6	DUF2254 domain-containing protein
MMJJ_RS07790		+0.2	1.3	hypothetical protein
MMJJ_RS05885		+0.2	1.5	tungstate ABC transporter substrate-binding protein WtpA
MMJJ_RS03235		+0.2	0.7	hypothetical protein
MMJJ_RS04300		+0.2	1.0	hypothetical protein
MMJJ_RS04585		+0.2	1.0	phenylacetate--CoA ligase
MMJJ_RS07215		+0.2	1.4	TIGR00341 family protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis JJ in rich t2 experiments