Experiment set2IT058 for Ralstonia sp. UNC404CL21Col

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Pimelic acid carbon source

200 most important genes:

  gene name fitness t score description  
ABZR87_RS13250 -7.7 -5.3 phosphoserine phosphatase SerB compare
ABZR87_RS08630 -7.3 -12.3 dihydroorotase compare
ABZR87_RS14505 -7.1 -4.9 phosphoribosylanthranilate isomerase compare
ABZR87_RS14540 -6.8 -8.1 3-isopropylmalate dehydratase large subunit compare
ABZR87_RS14500 -6.5 -11.6 tryptophan synthase subunit beta compare
ABZR87_RS02570 -6.4 -19.7 glutamate synthase-related protein compare
ABZR87_RS14535 -6.3 -4.4 3-isopropylmalate dehydratase small subunit compare
ABZR87_RS16170 -6.2 -6.1 argininosuccinate lyase compare
ABZR87_RS07360 -6.1 -16.4 threonine ammonia-lyase, biosynthetic compare
ABZR87_RS02160 -6.0 -7.1 indole-3-glycerol phosphate synthase TrpC compare
ABZR87_RS02565 -5.9 -5.8 glutamate synthase subunit beta compare
ABZR87_RS06770 -5.9 -10.6 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
ABZR87_RS13790 -5.9 -11.9 chorismate synthase compare
ABZR87_RS00200 -5.7 -5.5 phosphoadenylyl-sulfate reductase compare
ABZR87_RS02640 -5.6 -15.3 diaminopimelate decarboxylase compare
ABZR87_RS00190 -5.6 -11.3 sulfate adenylyltransferase subunit 1 compare
ABZR87_RS02145 -5.5 -3.8 aminodeoxychorismate/anthranilate synthase component II compare
ABZR87_RS00210 -5.4 -7.5 nitrite/sulfite reductase compare
ABZR87_RS09445 -5.4 -15.6 3-phosphoserine/phosphohydroxythreonine transaminase compare
ABZR87_RS14490 -5.4 -9.0 tryptophan synthase subunit alpha compare
ABZR87_RS08625 -5.4 -3.7 aspartate carbamoyltransferase catalytic subunit compare
ABZR87_RS02590 -5.2 -13.3 3-dehydroquinate synthase compare
ABZR87_RS14530 -5.0 -9.7 3-isopropylmalate dehydrogenase compare
ABZR87_RS02595 -5.0 -9.4 shikimate kinase compare
ABZR87_RS02155 -5.0 -8.7 anthranilate phosphoribosyltransferase compare
ABZR87_RS09450 -5.0 -10.1 prephenate dehydratase compare
ABZR87_RS09465 -5.0 -10.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
ABZR87_RS22970 -4.9 -11.8 cystathionine gamma-synthase family protein compare
ABZR87_RS09935 -4.8 -4.7 amino acid aminotransferase compare
ABZR87_RS02140 -4.8 -19.1 anthranilate synthase component I compare
ABZR87_RS05590 -4.8 -4.7 orotate phosphoribosyltransferase compare
ABZR87_RS04865 -4.8 -4.6 methylenetetrahydrofolate reductase [NAD(P)H] compare
ABZR87_RS01110 -4.8 -11.7 3-deoxy-7-phosphoheptulonate synthase AroG compare
ABZR87_RS00835 -4.6 -6.3 argininosuccinate synthase compare
ABZR87_RS05200 -4.6 -16.6 homoserine O-acetyltransferase compare
ABZR87_RS05170 -4.5 -3.1 acetylglutamate kinase compare
ABZR87_RS07380 -4.5 -17.5 FAD/FMN-binding oxidoreductase compare
ABZR87_RS11440 -4.5 -9.0 pyridoxal phosphate-dependent aminotransferase compare
ABZR87_RS21815 -4.4 -1.9 MarR family winged helix-turn-helix transcriptional regulator compare
ABZR87_RS00185 -4.3 -4.2 uroporphyrinogen-III C-methyltransferase compare
ABZR87_RS14950 -4.3 -4.2 acetolactate synthase small subunit compare
ABZR87_RS00435 -4.2 -13.5 ATP-dependent Clp protease ATP-binding subunit ClpA compare
ABZR87_RS12785 -4.1 -9.5 endopeptidase La compare
ABZR87_RS13415 -3.8 -9.4 IclR family transcriptional regulator compare
ABZR87_RS12790 -3.7 -7.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
ABZR87_RS01810 -3.6 -3.2 glutamate 5-kinase compare
ABZR87_RS07665 -3.6 -11.4 aminopeptidase P N-terminal domain-containing protein compare
ABZR87_RS14955 -3.4 -3.3 acetolactate synthase 3 catalytic subunit compare
ABZR87_RS05100 -3.4 -12.7 RNA polymerase-binding protein DksA compare
ABZR87_RS09100 -3.4 -11.6 acyl-CoA dehydrogenase compare
ABZR87_RS00220 -3.3 -8.8 CysB family HTH-type transcriptional regulator compare
ABZR87_RS12800 -3.3 -8.0 trigger factor compare
ABZR87_RS00285 -3.3 -2.3 acetylornithine transaminase compare
ABZR87_RS08695 -3.3 -15.7 capsular polysaccharide biosynthesis protein CapF compare
ABZR87_RS00195 -3.0 -2.9 sulfate adenylyltransferase subunit CysD compare
ABZR87_RS13175 -3.0 -2.9 tRNA-Leu compare
ABZR87_RS13475 -2.9 -10.0 PAS domain S-box protein compare
ABZR87_RS08645 -2.9 -1.8 dTDP-glucose 4,6-dehydratase compare
ABZR87_RS12795 -2.9 -6.8 ATP-dependent Clp endopeptidase proteolytic subunit ClpP compare
ABZR87_RS10780 -2.8 -5.0 PD-(D/E)XK nuclease family protein compare
ABZR87_RS05025 -2.8 -3.3 rod shape-determining protein MreC compare
ABZR87_RS16660 -2.8 -6.3 helix-turn-helix domain-containing protein compare
ABZR87_RS01615 -2.7 -3.2 RNB domain-containing ribonuclease compare
ABZR87_RS02655 -2.7 -11.0 anti-sigma factor compare
ABZR87_RS06715 -2.7 -3.3 PTS sugar transporter subunit IIA compare
ABZR87_RS14115 -2.6 -9.9 ATP-dependent zinc metalloprotease FtsH compare
ABZR87_RS08700 -2.5 -11.6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
ABZR87_RS00205 -2.5 -3.3 DUF934 domain-containing protein compare
ABZR87_RS06645 -2.5 -2.7 TlpA disulfide reductase family protein compare
ABZR87_RS11625 -2.5 -9.3 malate synthase A compare
ABZR87_RS15440 -2.4 -3.6 ribonuclease G compare
ABZR87_RS05015 -2.3 -6.2 penicillin-binding protein 2 compare
ABZR87_RS07635 -2.3 -3.1 crossover junction endodeoxyribonuclease RuvC compare
ABZR87_RS01645 -2.3 -4.1 type II 3-dehydroquinate dehydratase compare
ABZR87_RS06315 -2.3 -12.1 bifunctional isocitrate dehydrogenase kinase/phosphatase compare
ABZR87_RS11125 -2.1 -7.5 cell division protein ZapE compare
ABZR87_RS09515 -2.1 -2.0 cysteine synthase CysM compare
ABZR87_RS04785 -2.1 -8.3 phosphomethylpyrimidine synthase ThiC compare
ABZR87_RS02480 -2.0 -2.3 imidazole glycerol phosphate synthase subunit HisH compare
ABZR87_RS09895 -2.0 -2.0 DUF1841 family protein compare
ABZR87_RS20870 -1.9 -7.4 LysR family transcriptional regulator compare
ABZR87_RS23180 -1.9 -2.0 ABC transporter ATP-binding protein compare
ABZR87_RS07625 -1.9 -3.0 Holliday junction branch migration protein RuvA compare
ABZR87_RS22910 -1.9 -1.6 6-phosphogluconolactonase compare
ABZR87_RS10170 -1.9 -6.7 RseA family anti-sigma factor compare
ABZR87_RS07700 -1.8 -2.7 peptidylprolyl isomerase compare
ABZR87_RS07050 -1.8 -1.9 PTS IIA-like nitrogen regulatory protein PtsN compare
ABZR87_RS09460 -1.7 -4.4 prephenate dehydrogenase compare
ABZR87_RS16180 -1.7 -3.5 arginine/lysine/ornithine decarboxylase compare
ABZR87_RS10240 -1.7 -2.4 elongation factor P maturation arginine rhamnosyltransferase EarP compare
ABZR87_RS01605 -1.6 -8.1 shikimate dehydrogenase compare
ABZR87_RS17495 -1.6 -9.6 acyl-CoA synthetase compare
ABZR87_RS11815 -1.6 -7.8 [protein-PII] uridylyltransferase compare
ABZR87_RS04940 -1.6 -7.9 PAS domain-containing sensor histidine kinase compare
ABZR87_RS16960 -1.6 -3.8 HAMP domain-containing sensor histidine kinase compare
ABZR87_RS07705 -1.6 -4.2 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
ABZR87_RS10610 -1.6 -1.4 inositol monophosphatase family protein compare
ABZR87_RS00215 -1.6 -3.3 sulfite exporter TauE/SafE family protein compare
ABZR87_RS10550 -1.6 -1.7 outer membrane protein assembly factor BamC compare
ABZR87_RS08640 -1.6 -4.9 symmetrical bis(5'-nucleosyl)-tetraphosphatase compare
ABZR87_RS10085 -1.6 -2.4 Rne/Rng family ribonuclease compare
ABZR87_RS12585 -1.6 -5.9 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein compare
ABZR87_RS08795 -1.5 -4.5 undecaprenyl-diphosphate phosphatase compare
ABZR87_RS16185 -1.5 -2.2 dCTP deaminase compare
ABZR87_RS16080 -1.4 -2.7 P-II family nitrogen regulator compare
ABZR87_RS15240 -1.4 -2.3 YicC/YloC family endoribonuclease compare
ABZR87_RS07620 -1.4 -3.4 Holliday junction branch migration DNA helicase RuvB compare
ABZR87_RS13285 -1.4 -8.5 polyhydroxyalkanoate synthesis repressor PhaR compare
ABZR87_RS10175 -1.3 -5.8 MucB/RseB C-terminal domain-containing protein compare
ABZR87_RS21795 -1.3 -5.2 NUDIX domain-containing protein compare
ABZR87_RS05010 -1.3 -3.2 rod shape-determining protein RodA compare
ABZR87_RS03420 -1.3 -1.6 type II secretion system minor pseudopilin GspI compare
ABZR87_RS10195 -1.3 -3.9 signal peptidase I compare
ABZR87_RS08990 -1.3 -4.9 peptidoglycan-associated lipoprotein Pal compare
ABZR87_RS00385 -1.2 -1.6 response regulator transcription factor compare
ABZR87_RS01675 -1.2 -2.1 carbohydrate kinase family protein compare
ABZR87_RS03780 -1.2 -1.9 thiosulfate oxidation carrier protein SoxY compare
ABZR87_RS22300 -1.2 -1.2 flagellar biosynthesis anti-sigma factor FlgM compare
ABZR87_RS00745 -1.2 -1.9 3-hydroxyacyl-CoA dehydrogenase compare
ABZR87_RS10785 -1.2 -4.1 exodeoxyribonuclease V subunit beta compare
ABZR87_RS14575 -1.2 -3.1 GntR family transcriptional regulator compare
ABZR87_RS16125 -1.1 -4.9 heme biosynthesis protein HemY compare
ABZR87_RS08985 -1.1 -6.4 Tol-Pal system beta propeller repeat protein TolB compare
ABZR87_RS01555 -1.1 -1.3 barstar family protein compare
ABZR87_RS15505 -1.1 -1.3 DNA polymerase III subunit alpha compare
ABZR87_RS00875 -1.1 -2.6 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA compare
ABZR87_RS04210 -1.1 -5.5 ABC transporter ATP-binding protein compare
ABZR87_RS00830 -1.1 -3.0 pyrimidine/purine nucleoside phosphorylase compare
ABZR87_RS22920 -1.1 -3.8 phosphogluconate dehydratase compare
ABZR87_RS10620 -1.1 -1.3 serine O-acetyltransferase compare
ABZR87_RS18335 -1.0 -1.5 GntR family transcriptional regulator compare
ABZR87_RS14510 -1.0 -2.9 tRNA pseudouridine(38-40) synthase TruA compare
ABZR87_RS15705 -1.0 -2.4 UvrD-helicase domain-containing protein compare
ABZR87_RS10565 -1.0 -2.7 cupin domain-containing protein compare
ABZR87_RS16250 -1.0 -2.8 iron-sulfur cluster carrier protein ApbC compare
ABZR87_RS04945 -1.0 -2.7 DUF4390 domain-containing protein compare
ABZR87_RS02515 -1.0 -2.3 BolA family protein compare
ABZR87_RS00970 -1.0 -1.4 molecular chaperone DnaJ compare
ABZR87_RS11770 -1.0 -4.5 succinyldiaminopimelate transaminase compare
ABZR87_RS07020 -1.0 -6.9 dynamin-like GTPase family protein compare
ABZR87_RS23415 -1.0 -1.7 metalloregulator ArsR/SmtB family transcription factor compare
ABZR87_RS02575 -1.0 -3.7 transposase compare
ABZR87_RS07035 -1.0 -5.0 RNase adapter RapZ compare
ABZR87_RS04215 -1.0 -2.1 ABC transporter ATP-binding protein compare
ABZR87_RS14665 -1.0 -1.5 histidine phosphatase family protein compare
ABZR87_RS08655 -1.0 -3.2 glucose-1-phosphate thymidylyltransferase RfbA compare
ABZR87_RS00795 -1.0 -2.9 site-specific tyrosine recombinase XerD compare
ABZR87_RS05145 -0.9 -1.4 copper chaperone PCu(A)C compare
ABZR87_RS08970 -0.9 -4.5 protein TolQ compare
ABZR87_RS09200 -0.9 -7.3 long-chain fatty acid--CoA ligase compare
ABZR87_RS09955 -0.9 -5.1 LacI family DNA-binding transcriptional regulator compare
ABZR87_RS22690 -0.9 -1.7 XRE family transcriptional regulator compare
ABZR87_RS08585 -0.9 -2.4 chemotaxis protein CheW compare
ABZR87_RS04195 -0.9 -6.3 branched-chain amino acid ABC transporter permease compare
ABZR87_RS08800 -0.9 -1.4 NADH:flavin oxidoreductase/NADH oxidase compare
ABZR87_RS06325 -0.8 -4.4 MerR family DNA-binding transcriptional regulator compare
ABZR87_RS06395 -0.8 -3.9 response regulator compare
ABZR87_RS04640 -0.8 -2.1 hypothetical protein compare
ABZR87_RS09615 -0.8 -1.7 50S ribosomal protein L19 compare
ABZR87_RS18320 -0.8 -2.0 HEAT repeat domain-containing protein compare
ABZR87_RS14495 -0.8 -3.1 site-specific DNA-methyltransferase compare
ABZR87_RS05065 -0.8 -2.9 tyrosine recombinase XerC compare
ABZR87_RS16740 -0.8 -4.3 2-methylcitrate synthase compare
ABZR87_RS06705 -0.8 -5.8 glutamate--cysteine ligase compare
ABZR87_RS15955 -0.8 -1.4 pyrroloquinoline quinone biosynthesis peptide chaperone PqqD compare
ABZR87_RS15405 -0.8 -1.8 YebC/PmpR family DNA-binding transcriptional regulator compare
ABZR87_RS22750 -0.8 -2.0 response regulator transcription factor compare
ABZR87_RS07675 -0.8 -4.8 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU compare
ABZR87_RS11560 -0.8 -1.8 2TM domain-containing protein compare
ABZR87_RS21585 -0.8 -1.7 multidrug efflux SMR transporter compare
ABZR87_RS06495 -0.8 -2.0 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase compare
ABZR87_RS06400 -0.8 -5.7 response regulator transcription factor compare
ABZR87_RS13350 -0.8 -3.1 potassium transporter Kup compare
ABZR87_RS13300 -0.8 -3.8 class I poly(R)-hydroxyalkanoic acid synthase compare
ABZR87_RS06405 -0.8 -0.9 hypothetical protein compare
ABZR87_RS01145 -0.8 -2.1 glycolate oxidase subunit GlcE compare
ABZR87_RS06845 -0.8 -4.1 heme o synthase compare
ABZR87_RS02445 -0.8 -2.7 Sec-independent protein translocase protein TatB compare
ABZR87_RS23095 -0.8 -0.8 MarR family transcriptional regulator compare
ABZR87_RS20430 -0.8 -2.0 YfiR family protein compare
ABZR87_RS07435 -0.7 -2.7 DUF502 domain-containing protein compare
ABZR87_RS05060 -0.7 -2.1 DUF484 family protein compare
ABZR87_RS17760 -0.7 -1.5 ATP-binding cassette domain-containing protein compare
ABZR87_RS04200 -0.7 -3.7 branched-chain amino acid ABC transporter permease compare
ABZR87_RS01640 -0.7 -2.6 TlpA disulfide reductase family protein compare
ABZR87_RS20155 -0.7 -2.9 type VI secretion system-associated protein TagF compare
ABZR87_RS07335 -0.7 -2.0 hypothetical protein compare
ABZR87_RS02385 -0.7 -2.8 ubiquinol-cytochrome c reductase iron-sulfur subunit compare
ABZR87_RS07730 -0.7 -1.5 lysophospholipid acyltransferase family protein compare
ABZR87_RS03015 -0.7 -4.5 DeoR/GlpR family DNA-binding transcription regulator compare
ABZR87_RS22625 -0.7 -2.3 hypothetical protein compare
ABZR87_RS06710 -0.7 -5.5 glutathione synthase compare
ABZR87_RS05350 -0.7 -2.3 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE compare
ABZR87_RS12625 -0.7 -5.4 3-(methylthio)propionyl-CoA ligase conserved
ABZR87_RS17560 -0.7 -4.6 ABC transporter substrate-binding protein compare
ABZR87_RS16735 -0.7 -6.0 Fe/S-dependent 2-methylisocitrate dehydratase AcnD compare
ABZR87_RS01360 -0.7 -5.8 response regulator compare
ABZR87_RS17525 -0.7 -4.8 helix-turn-helix domain-containing protein compare
ABZR87_RS12260 -0.7 -2.3 (2Fe-2S)-binding protein compare
ABZR87_RS14965 -0.7 -2.2 DUF3619 family protein compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source Pimelic acid in Ralstonia sp. UNC404CL21Col

For carbon source Pimelic acid across organisms