Experiment set2IT057 for Sinorhizobium meliloti 1021

Compare to:

LB with D-Cycloserine 0.05 mg/ml

200 most important genes:

  gene name fitness t score description  
SMc02850 -5.5 -3.8 DNA polymerase I compare
SMc02077 -4.8 -3.1 exodeoxyribonuclease III protein compare
SMc00334 -4.6 -2.3 cytidylate kinase compare
SMc01881 -4.6 -4.5 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc00557 -4.6 -5.5 alanine racemase compare
SMc00619 -4.4 -2.7 hypothetical protein compare
SMc00483 -4.3 -7.4 glutamate racemase conserved
SM_b20307 -4.1 -1.2 dihydroxyacetone kinase compare
SMc02144 -4.1 -6.7 phosphate ABC transporter permease compare
SMc03967 -3.6 -1.9 Holliday junction resolvase compare
SMc01880 -3.5 -3.4 pantoate--beta-alanine ligase compare
SMc01850 -3.3 -3.9 hypothetical protein compare
SM_b21633 -3.1 -1.3 enoyl-CoA hydratase compare
SMc02753 -3.0 -1.6 PTS system transporter subunit IIA compare
SMc01147 -3.0 -3.6 coproporphyrinogen III oxidase compare
SMc02140 -3.0 -2.2 phosphate regulon transcriptional regulatory protein compare
SMc02147 -3.0 -7.8 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02778 -2.9 -1.2 hydroxyacid aldolase compare
SMc00712 -2.9 -2.3 hypothetical protein compare
SMc02142 -2.8 -5.0 phosphate transporter ATP-binding protein compare
SMc02495 -2.8 -1.7 translaldolase compare
SMc00640 -2.7 -9.6 phosphoserine aminotransferase compare
SMc00602 -2.5 -5.7 excinuclease ABC subunit C compare
SMc04296 -2.5 -1.1 cell division protein FtsZ compare
SMc00760 -2.5 -6.1 recombinase A compare
SMc00970 -2.5 -3.2 exodeoxyribonuclease VII small subunit compare
SMc00580 -2.4 -4.5 4-hydroxythreonine-4-phosphate dehydrogenase compare
SMc01347 -2.4 -5.2 hypothetical protein compare
SMc02071 -2.3 -3.9 hydrolase glycosidase compare
SMc02510 -2.3 -1.0 ferric uptake regulation protein compare
SM_b20039 -2.2 -8.5 transcriptional regulator conserved
SM_b20143 -2.2 -1.3 oligopeptide ABC transporter permease compare
SMc01342 -2.2 -5.4 hypothetical protein compare
SMc02833 -2.2 -2.3 penicillin-insensitive murein endopeptidase compare
SMc02114 -2.2 -3.3 hypothetical protein compare
SMc01235 -2.1 -13.0 excinuclease ABC subunit A compare
SMc02867 -2.1 -3.7 multidrug-efflux system transmembrane protein compare
SMa5033 -2.0 -1.1 hypothetical protein compare
SMc02909 -2.0 -1.7 transglycosylase transmembrane protein compare
SMc01364 -2.0 -1.2 DNA topoisomerase I compare
SMc00987 -2.0 -2.9 hypothetical protein compare
SMc01447 -2.0 -1.4 hypothetical protein compare
SMc01877 -1.9 -6.8 DNA repair protein compare
SMc00067 -1.9 -7.5 outer-membranne lipoprotein compare
SMc02234 -1.9 -2.5 hypothetical protein compare
SMc02505 -1.9 -1.0 hypothetical protein compare
SMc03773 -1.8 -6.3 hypothetical protein compare
SMa1924 -1.8 -1.0 hypothetical protein compare
SMa2289 -1.8 -1.2 hypothetical protein compare
SMc00928 -1.8 -1.2 signal peptide protein compare
SMc00963 -1.8 -4.4 hypothetical protein compare
SMc02102 -1.8 -3.5 hypothetical protein compare
SMc00914 -1.8 -3.8 oxidoreductase compare
SMc02812 -1.8 -1.8 hypothetical protein compare
SMc04174 -1.8 -1.6 signal peptide protein compare
SMa0789 -1.7 -3.6 GntR family transcriptional regulator compare
SMc03978 -1.7 -3.4 transketolase compare
SMc03242 -1.7 -2.8 GTP-binding protein compare
SMc02115 -1.7 -0.9 hypothetical protein compare
SM_b21523 -1.7 -2.8 cell division inhibitor protein compare
SMc03050 -1.7 -2.1 flagellar biosynthesis regulatory protein FlaF compare
SMc00556 -1.7 -4.3 DNA repair protein RadA compare
SMc02149 -1.7 -1.7 hypothetical protein compare
SMc03227 -1.6 -3.0 hypothetical protein compare
SMc00726 -1.6 -0.7 thiol:disulfide interchange redox-active center transmembrane protein compare
SMc02232 -1.6 -2.2 hypothetical protein compare
SMc05011 -1.6 -3.2 bacteriophage DNA-binding transcription regulator compare
SMc02046 -1.6 -1.4 hypothetical protein compare
SMc00511 -1.6 -4.5 D-ribulose-5-phosphate 3-epimerase compare
SMc03979 -1.6 -2.4 glyceraldehyde-3-phosphate dehydrogenase compare
SMc03181 -1.6 -6.2 monovalent cation/H+ antiporter subunit D compare
SMc02484 -1.6 -3.3 amino acid efflux transmembrane protein compare
SMa0112 -1.6 -3.5 hypothetical protein compare
SMc02868 -1.5 -3.9 multidrug efflux system protein compare
SMc03179 -1.5 -9.9 monovalent cation/H+ antiporter subunit A compare
SMc00815 -1.5 -1.8 inosine 5'-monophosphate dehydrogenase compare
SMc02739 -1.5 -3.7 glycine betaine transport ATP-binding ABC transporter protein compare
SMc00073 -1.5 -1.8 hypothetical protein compare
SMc00492 -1.5 -0.9 hypothetical protein compare
SMc00667 -1.5 -2.1 hypothetical protein compare
SMc03183 -1.5 -7.0 monovalent cation/H+ antiporter subunit F compare
SMc01845 -1.5 -2.2 transglycosylase transmembrane protein compare
SMc00579 -1.5 -3.2 dimethyladenosine transferase compare
SMc03180 -1.4 -3.0 monovalent cation/H+ antiporter subunit C compare
SMc00378 -1.4 -2.4 exodeoxyribonuclease VII large subunit compare
SMa1118 -1.4 -1.6 HspC2 heat shock protein compare
SMc00555 -1.4 -1.1 colicin V production transmembrane protein compare
SMc04024 -1.4 -3.4 membrane-bound lytic murein transglycosylase compare
SMc01220 -1.4 -4.4 lipopolysaccharide core biosynthesis glycosyl transferase compare
SMc01461 -1.4 -3.7 DNA helicase II protein compare
SMa0905 -1.4 -1.1 hypothetical protein compare
SMc02906 -1.3 -0.8 hypothetical protein compare
SMc00359 -1.3 -6.2 hypothetical protein compare
SM_b20055 -1.3 -1.3 transcriptional regulator compare
SMc02641 -1.3 -4.3 UDP-glucose 6-dehydrogenase compare
SMc02145 -1.3 -0.7 signal peptide protein compare
SMc02266 -1.3 -1.5 hypothetical protein compare
SMc02143 -1.3 -2.6 phosphate ABC transporter permease compare
SM_b20452 -1.3 -2.5 hypothetical protein compare
SMc02886 -1.3 -1.8 signal peptide protein compare
SM_b20040 -1.3 -3.8 hypothetical protein compare
SMc01438 -1.3 -4.3 protease precursor signal peptide protein compare
SMc02866 -1.3 -2.5 transcriptional regulator compare
SMc03140 -1.3 -3.8 transcriptional regulator compare
SMc02758 -1.3 -2.8 nucleotidyl transferase compare
SMc00691 -1.3 -2.8 site-specific tyrosine recombinase XerD compare
SMc01187 -1.2 -1.4 rare lipoprotein A compare
SMc00351 -1.2 -0.9 hypothetical protein compare
SMa0312 -1.2 -2.1 hypothetical protein compare
SMc03774 -1.2 -2.1 hypothetical protein compare
SM_b20075 -1.2 -1.5 hypothetical protein compare
SMc02724 -1.2 -1.7 hypothetical protein compare
SMa1239 -1.2 -1.6 NapD component of periplasmic nitrate reductase compare
SMc02856 -1.2 -6.8 penicillin-binding protein compare
SMc02435 -1.2 -1.9 methyltransferase compare
SMc02685 -1.2 -1.7 hypothetical protein compare
SM_b20258 -1.2 -3.1 transcriptional regulator compare
SMc01700 -1.2 -3.9 peptidyl-prolyl cis-trans isomerase A compare
SM_b21035 -1.2 -2.9 hypothetical protein compare
SM_b20823 -1.2 -5.1 cell surface saccharide synthesis protein compare
SMc03746 -1.2 -1.6 hypothetical protein compare
SMc03182 -1.1 -3.5 pH adaptation potassium efflux system E transmembrane protein compare
SMc00228 -1.1 -5.8 ATP-dependent DNA helicase RecG compare
SM_b20069 -1.1 -4.0 amino acid carrier protein compare
SMc00775 -1.1 -7.1 iron(III) permease compare
SMc03827 -1.1 -2.7 amino acid efflux transmembrane protein compare
SMc00656 -1.1 -1.2 hypothetical protein compare
SM_b21524 -1.1 -1.8 septum formation inhibitor compare
SMc01553 -1.1 -1.3 acyl carrier protein compare
SM_b20117 -1.1 -1.4 sugar transferase compare
SMc04231 -1.1 -3.9 excinuclease ABC subunit B compare
SMa1323 -1.1 -1.5 Transcription regulator compare
SMc02068 -1.1 -5.5 ABC transporter ATP-binding protein compare
SM_b20450 -1.1 -6.7 regulatory protein compare
SMc01183 -1.1 -1.2 LexA repressor compare
SMc02694 -1.1 -0.9 ATP-dependent Clp protease adaptor compare
SMc02849 -1.1 -5.3 2-hydroxyacid dehydrogenase compare
SMc03836 -1.1 -1.2 acyl-CoA thioesterase i protein compare
SMc01701 -1.1 -1.6 hypothetical protein compare
SMc04121 -1.1 -0.7 uracil phosphoribosyltransferase compare
SM_b20105 -1.1 -0.9 transcriptional regulator compare
SMc00353 -1.0 -1.2 transmembrane protein compare
SM_b21347 -1.0 -1.4 pectin degradation protein compare
SMc03127 -1.0 -1.1 ABC transporter permease compare
SMc00784 -1.0 -5.4 iron binding protein compare
SMc03935 -1.0 -5.5 hypothetical protein compare
SMc02635 -1.0 -4.1 DNA repair protein RecO compare
SMc02451 -1.0 -1.2 hypothetical protein compare
SMc03229 -1.0 -0.8 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc03124 -1.0 -2.5 periplasmic binding ABC transporter protein compare
SMa1325 -1.0 -1.4 hypothetical protein compare
SMa1053 -1.0 -1.2 hypothetical protein compare
SMc00241 -1.0 -1.1 transcriptional regulator compare
SM_b20074 -1.0 -2.3 hypothetical protein compare
SMc01204 -1.0 -5.1 transmembrane oxidoreductase compare
SM_b21580 -1.0 -1.4 hypothetical protein compare
SMc04085 -1.0 -2.9 hypothetical protein compare
SMc01361 -1.0 -3.1 dihydroorotase compare
SMc03312 -1.0 -1.5 transposase ISRM11/ISRM2011-2 compare
SM_b21359 -1.0 -2.5 LysR family transcriptional regulator compare
SMc01153 -1.0 -0.8 enoyl-CoA hydratase compare
SMc01208 -1.0 -1.4 peptidyl-prolyl cis-trans isomerase B protein compare
SMc02863 -1.0 -2.0 recombination protein F compare
SMc02307 -1.0 -3.5 histidinol dehydrogenase compare
SM_b20616 -0.9 -1.6 thiamine biosynthesis oxidoreductase compare
SMc00396 -0.9 -1.9 hypothetical protein compare
SMc03993 -0.9 -2.6 hypothetical protein compare
SMc04330 -0.9 -1.5 trimethylamine methyltransferase compare
SMc01853 -0.9 -2.9 hypothetical protein compare
SMc03763 -0.9 -1.5 cytosine-specific methyltransferase compare
SMa1092 -0.9 -1.6 hypothetical protein compare
SMc01716 -0.9 -5.0 sensor histidine kinase transmembrane protein compare
SMc02901 -0.9 -0.6 hypothetical protein compare
SM_b20901 -0.9 -4.4 transcriptional regulator compare
SMc00451 -0.9 -3.3 processing protease compare
SMc02941 -0.9 -2.8 hypothetical protein compare
SMa1894 -0.9 -1.3 methionine sulfoxide reductase B compare
SMc01360 -0.9 -1.5 aspartate carbamoyltransferase catalytic subunit compare
SMc00239 -0.9 -0.6 hypothetical protein compare
SMc00461 -0.9 -1.1 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
SMc03923 -0.9 -4.5 glucose-1-phosphate adenylyltransferase compare
SMa1052 -0.9 -1.0 hypothetical protein compare
SMc00088 -0.8 -1.1 hypothetical protein compare
SMc03060 -0.8 -3.8 transcriptional regulator compare
SMc00025 -0.8 -4.2 pyruvate phosphate dikinase compare
SMc00675 -0.8 -5.5 hypothetical protein compare
SMc00103 -0.8 -3.4 alpha-halocarboxylic acid dehalogenase compare
SMc02593 -0.8 -1.9 hypothetical protein compare
SMc02827 -0.8 -1.9 hypothetical protein compare
SMa0748 -0.8 -1.1 MucR family transcriptional regulator compare
SMc02904 -0.8 -1.0 hypothetical protein compare
SMc02780 -0.8 -3.2 succinate-semialdehyde dehydrogenase [NADP+] protein compare
SM_b20595 -0.8 -2.4 cell division protein FtsK compare
SM_b20580 -0.8 -1.5 LysR family transcriptional regulator compare
SMc02333 -0.8 -1.6 hypothetical protein compare
SMc01725 -0.8 -2.1 hypothetical protein compare
SM_b21099 -0.8 -3.4 hypothetical protein compare
SMc01974 -0.8 -1.8 transcriptional regulator compare
SMc01328 -0.8 -2.1 hypothetical protein compare
SMa1779 -0.8 -1.3 hypothetical protein compare


Specific Phenotypes

For 14 genes in this experiment

For stress D-Cycloserine in Sinorhizobium meliloti 1021

For stress D-Cycloserine across organisms